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The map label for this gene is hflX [H]

Identifier: 78355423

GI number: 78355423

Start: 370684

End: 372156

Strand: Reverse

Name: hflX [H]

Synonym: Dde_0376

Alternate gene names: 78355423

Gene position: 372156-370684 (Counterclockwise)

Preceding gene: 78355424

Following gene: 78355422

Centisome position: 9.98

GC content: 61.98

Gene sequence:

>1473_bases
ATGCTCGACAGACAGGGCAGGGTTTCTCTGGTTATTGTGGGCGATACGGGCTCCATCTATATTCCCGAGCTTCCCCGCGC
CCGAACGGGCGCGGGCAGGCTGCGGGGGCTCAGGCTGCTGCACACCCACCTGACTGACTCCCTGCTTTCGCAGGAAGACC
TCATGGACATGCTGTTTCTGCGTCTTGACGACGTGGGCGTGCTCACCGTGGACCAGCACGGCGGGCCGGCCAGCTTTCAG
CATGCGCATCTGCTGCCCGGCGGCACACAGCCCTACATGGTGCACGACCCGCAGGGGTGGGACAGGGTAATAACAGATTT
CACCGCACAGGCGCAGGCGCTGGAAGAAGAACTTTCGCGCATCACCGCCGATGCCCGCGAAACCGGCAGCGAATCCGGCA
GGGCAGTGCTGGTGAGTGTTTCTCCCGACCCGCGTTCCGTGCAGGAATCGTCGCTGGCCGAACTGGCCGAACTGGCCGAT
ACCGCCGGGCTGACCGTGGCGGGCACCATGGTGCAGCGCGTACGGCAGCTCAACTACAAATTCATTCTGGGCAAGGGCAA
ACTGGCCGAACTTGAAGTGCTTGCGCTTACGGCAAACGCCGGAGTCATCCTTTTTGACGGAGAACTGTCGCCCGCGCAGC
TGCACAACCTTGCCGATATCACCGAACGCAAGGTTATAGACCGCACCCAGCTTATTCTGGATATTTTCGCCCAGCGCGCT
TCCACGCGTGCGGGCAAACTGCAGGTGGAACTGGCCCAGCTGCAATACACACAGCCCCGCCTGACCGGAAAAAACCGCGC
CATGGACAGGCTGGCAGGCGGCATTGGCGGCCGCGGCCCCGGTGAAACCAAACTGGAAACCGACCGCCGCAAGGTGCGCG
AACGCATAGCCCGCATCAAGCAGGACCTCAAAGCTCTGCGCACCCAGCGCGGTTTCACCCGCGGCCGCAGAGCCAAGGCG
CGTGTGCCTGTGGCATCGCTGGTGGGGTACACCAACGCGGGCAAATCAACGCTGCTCAACACTCTGACCAATGCAGACGT
GCTGGCCGAAGACAAGCTGTTTGCCACGCTGGACACCACCACCCGCAGACTGCGCTTTCCGCAGGAACGCGAACTCATCG
TCACCGACACGGTGGGTTTCATCCGCTCGCTGCCCAAGGAACTCAAAGAGGCATTCCGGGCCACTCTTGAAGAACTGGAA
GCCGCTGATCTGCTGCTGCATGTGGCCGATGCCGGACACCCCGAGCTGGAAATGCAGCTGCGCGCGGTGGAAGAGATTCT
GGACGAGCTGGAACTGCAGGATATTCCGCGGCTTCTGGTGCTCAACAAATGGGAAACGCTGGACGATGAAACCCGTCTGG
CCCTTGCCGCCCTGTACCCTGCCGCCATCCGCGTTTCCGCCAGAACACGGCTTGGCCTTGATGACCTCACCGCAGAAATC
ATCAGACGCATAGACTGGGAGCGGATGCTGTAG

Upstream 100 bases:

>100_bases
TCTGTACACACGCCGCTACCCTGCCGAGGGCGGCTACACCACGGAACAGGCAAGAGAACTGGCCGCCCTGAGCCGCAGCA
TAGGCCGTCAGATAGGGCTG

Downstream 100 bases:

>100_bases
CCGGCCCCTGCAGCCTCCGCGTATTAACCGCCGCACACAACCGTAAGCCGGGGCCTGCACGGCAGAACACGCTGCGGCCT
ATTCCGCACAGGCCGCAGGC

Product: GTP-binding protein HflX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 490; Mature: 490

Protein sequence:

>490_residues
MLDRQGRVSLVIVGDTGSIYIPELPRARTGAGRLRGLRLLHTHLTDSLLSQEDLMDMLFLRLDDVGVLTVDQHGGPASFQ
HAHLLPGGTQPYMVHDPQGWDRVITDFTAQAQALEEELSRITADARETGSESGRAVLVSVSPDPRSVQESSLAELAELAD
TAGLTVAGTMVQRVRQLNYKFILGKGKLAELEVLALTANAGVILFDGELSPAQLHNLADITERKVIDRTQLILDIFAQRA
STRAGKLQVELAQLQYTQPRLTGKNRAMDRLAGGIGGRGPGETKLETDRRKVRERIARIKQDLKALRTQRGFTRGRRAKA
RVPVASLVGYTNAGKSTLLNTLTNADVLAEDKLFATLDTTTRRLRFPQERELIVTDTVGFIRSLPKELKEAFRATLEELE
AADLLLHVADAGHPELEMQLRAVEEILDELELQDIPRLLVLNKWETLDDETRLALAALYPAAIRVSARTRLGLDDLTAEI
IRRIDWERML

Sequences:

>Translated_490_residues
MLDRQGRVSLVIVGDTGSIYIPELPRARTGAGRLRGLRLLHTHLTDSLLSQEDLMDMLFLRLDDVGVLTVDQHGGPASFQ
HAHLLPGGTQPYMVHDPQGWDRVITDFTAQAQALEEELSRITADARETGSESGRAVLVSVSPDPRSVQESSLAELAELAD
TAGLTVAGTMVQRVRQLNYKFILGKGKLAELEVLALTANAGVILFDGELSPAQLHNLADITERKVIDRTQLILDIFAQRA
STRAGKLQVELAQLQYTQPRLTGKNRAMDRLAGGIGGRGPGETKLETDRRKVRERIARIKQDLKALRTQRGFTRGRRAKA
RVPVASLVGYTNAGKSTLLNTLTNADVLAEDKLFATLDTTTRRLRFPQERELIVTDTVGFIRSLPKELKEAFRATLEELE
AADLLLHVADAGHPELEMQLRAVEEILDELELQDIPRLLVLNKWETLDDETRLALAALYPAAIRVSARTRLGLDDLTAEI
IRRIDWERML
>Mature_490_residues
MLDRQGRVSLVIVGDTGSIYIPELPRARTGAGRLRGLRLLHTHLTDSLLSQEDLMDMLFLRLDDVGVLTVDQHGGPASFQ
HAHLLPGGTQPYMVHDPQGWDRVITDFTAQAQALEEELSRITADARETGSESGRAVLVSVSPDPRSVQESSLAELAELAD
TAGLTVAGTMVQRVRQLNYKFILGKGKLAELEVLALTANAGVILFDGELSPAQLHNLADITERKVIDRTQLILDIFAQRA
STRAGKLQVELAQLQYTQPRLTGKNRAMDRLAGGIGGRGPGETKLETDRRKVRERIARIKQDLKALRTQRGFTRGRRAKA
RVPVASLVGYTNAGKSTLLNTLTNADVLAEDKLFATLDTTTRRLRFPQERELIVTDTVGFIRSLPKELKEAFRATLEELE
AADLLLHVADAGHPELEMQLRAVEEILDELELQDIPRLLVLNKWETLDDETRLALAALYPAAIRVSARTRLGLDDLTAEI
IRRIDWERML

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133118, Length=232, Percent_Identity=37.5, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI310133116, Length=224, Percent_Identity=37.5, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI310124269, Length=207, Percent_Identity=38.6473429951691, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI310124267, Length=207, Percent_Identity=38.6473429951691, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI310124171, Length=207, Percent_Identity=38.6473429951691, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI310124169, Length=207, Percent_Identity=38.6473429951691, Blast_Score=124, Evalue=2e-28,
Organism=Escherichia coli, GI1790615, Length=338, Percent_Identity=46.4497041420118, Blast_Score=260, Evalue=2e-70,
Organism=Caenorhabditis elegans, GI17561038, Length=275, Percent_Identity=29.8181818181818, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24650079, Length=353, Percent_Identity=31.728045325779, Blast_Score=117, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 54346; Mature: 54346

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDRQGRVSLVIVGDTGSIYIPELPRARTGAGRLRGLRLLHTHLTDSLLSQEDLMDMLFL
CCCCCCCEEEEEEECCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLDDVGVLTVDQHGGPASFQHAHLLPGGTQPYMVHDPQGWDRVITDFTAQAQALEEELSR
HHCCCEEEEEECCCCCCCCCCEEECCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHH
ITADARETGSESGRAVLVSVSPDPRSVQESSLAELAELADTAGLTVAGTMVQRVRQLNYK
HHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCE
FILGKGKLAELEVLALTANAGVILFDGELSPAQLHNLADITERKVIDRTQLILDIFAQRA
EEECCCCCCEEEEEEEEECCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
STRAGKLQVELAQLQYTQPRLTGKNRAMDRLAGGIGGRGPGETKLETDRRKVRERIARIK
CCCCCEEEEEEEHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHH
QDLKALRTQRGFTRGRRAKARVPVASLVGYTNAGKSTLLNTLTNADVLAEDKLFATLDTT
HHHHHHHHHHCCCCCCCCCCCCCHHHHHCCCCCCHHHHHHHHCCCCCEECCCEEEEEHHH
TRRLRFPQERELIVTDTVGFIRSLPKELKEAFRATLEELEAADLLLHVADAGHPELEMQL
HHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
RAVEEILDELELQDIPRLLVLNKWETLDDETRLALAALYPAAIRVSARTRLGLDDLTAEI
HHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHHHEEEHHHHCCHHHHHHHH
IRRIDWERML
HHHHHHHHCC
>Mature Secondary Structure
MLDRQGRVSLVIVGDTGSIYIPELPRARTGAGRLRGLRLLHTHLTDSLLSQEDLMDMLFL
CCCCCCCEEEEEEECCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLDDVGVLTVDQHGGPASFQHAHLLPGGTQPYMVHDPQGWDRVITDFTAQAQALEEELSR
HHCCCEEEEEECCCCCCCCCCEEECCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHH
ITADARETGSESGRAVLVSVSPDPRSVQESSLAELAELADTAGLTVAGTMVQRVRQLNYK
HHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCE
FILGKGKLAELEVLALTANAGVILFDGELSPAQLHNLADITERKVIDRTQLILDIFAQRA
EEECCCCCCEEEEEEEEECCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
STRAGKLQVELAQLQYTQPRLTGKNRAMDRLAGGIGGRGPGETKLETDRRKVRERIARIK
CCCCCEEEEEEEHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHH
QDLKALRTQRGFTRGRRAKARVPVASLVGYTNAGKSTLLNTLTNADVLAEDKLFATLDTT
HHHHHHHHHHCCCCCCCCCCCCCHHHHHCCCCCCHHHHHHHHCCCCCEECCCEEEEEHHH
TRRLRFPQERELIVTDTVGFIRSLPKELKEAFRATLEELEAADLLLHVADAGHPELEMQL
HHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
RAVEEILDELELQDIPRLLVLNKWETLDDETRLALAALYPAAIRVSARTRLGLDDLTAEI
HHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHHHEEEHHHHCCHHHHHHHH
IRRIDWERML
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]