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The map label for this gene is dppA [H]

Identifier: 78355322

GI number: 78355322

Start: 265905

End: 267692

Strand: Reverse

Name: dppA [H]

Synonym: Dde_0275

Alternate gene names: 78355322

Gene position: 267692-265905 (Counterclockwise)

Preceding gene: 78355323

Following gene: 78355321

Centisome position: 7.18

GC content: 56.94

Gene sequence:

>1788_bases
GTGACATATCAATGGCATTTGAAGCGAAAAGCCCTTGACGGCGGCGGCGTTGCTCGGTTTAGATGGGGCGATTTTTCATC
GGCAGCCCCTTATCCCCGTACCGGCGACTGCGGAAGTGCGCCGGCAAAGCAGGGCACCGCTTTTATGCAAAATTTCATTT
GGAGGTACTGGATGAAGCGCGTCTTGAAACTCATGCTGCTTGCACTGGTTGCAAGTCTGGCATTCGGCTGCAGCGCCGAG
CCGGAAGAAAAAAAGGCTGAATCGGCCCCCGCCGAAAAGGCCGCCGAAGCGCCCAAGGCAGAAAAAAAGGTTCTGCACCT
TGCCATGGATGCCGACCCTGTGTCTCTGGACCCCCATGTGCAGCTTTCCGGCGGCATGCTGCAGTATTCGCATCTGGTGT
TCGACCCCCTCGTCCGCTGGACGCAGGATATGGCCTTTGAACCCCGCCTTGCCGAAAAGTACGAGCGCATAGACCCCCTG
ACCATGCGCTTTCACCTGCGCAAGGGCGTCAAGTTCCACAGCGGCAATGAATTTACCGCCAAAGACGTGGTGTGGACGCT
GGCCCGTCTGAAAAAATCGCAGGACTACAAAGCCCTGTTCGAGCCTTTTGCCGAGCCCAAGATCATCGACGACTACACCA
TCGATCTGATCACCCACAAGCCCTACCCCCTGATGCTGAACATGGCCACCTACATCTTCCCCATGGACAGCAAGTTCTAC
AGCGGAAACGATGAAAACGGCCAGCCCAAGGACGCCATCGTAAAGACCGGCCCCTCCTTTGCCAACGTCAACGAATCCGG
CACCGGTCCCTTTACCGTGGAATCCCGCGAACAGGGCGTGCGCATGGTATTCAAGGCATTTCCCGGATACTGGGGCCCCC
GCGGCAACGTGGAAGAAATCGACCTGAAGCCCATCAAGAACGACGCCACCCGCGTGGCATCCATTCTGTCCGGCGATGTT
GATTTCATCATGCCTGTTCCGCCTCAGGACTACGACCGTCTGGCCAACCACGAAACTGTCAAGCTGATCACCATGGCCGG
TTCGCGCCTGATCACCCTGCAGATGAACCAGAACCGCGTGGAAGCCTTCAAGGATCCCCGCGTGCGTCAGGCCGTTGTAT
ACGCCACCGACAATCAGGGCATTGCCGAAAAAATCATGAAAGGCCGCGCCACCGCAGCCGGTCAGCAGAGCCCCGAAGGC
TTCTACAGCTACGTGCCCGAACTGGCACCCCGCTATGACCTGGAAAAGGCCAAGCAGCTCATGAAGGAAGCCGGCTACGA
AAAGGGCTTTGAAGTTACCATGATCGCCCCCAACAACCGCTACGTGAACGATGAAAAGGTCGCCGAAGCGTTTGTTTCCA
TGATGGCCAAAATCGGCATCACCGTGAACCTGAAGACCATGCCCAAGGCTCAGTACTGGGATGAGTTTGACGCACAGGTG
GCCGACATCCAGATGGTGGGCTGGCACCCCGATACCGAAGACTCCGCCAACTACACCGAGTTTCTGCTGATGTGCCCCAA
TAAGGAAACCGGCTACGGCCAGTACAACAGCGGCAACTACTGCAACAAAAAGGTGGACGAGCTGACCATCGCCTCGCAGA
GCGAGACCGACAAGGCAAAGCGCACCGCACTGCTGCAGGAAGCTGAAAAAATCATCTACGAAGAGGCCGCCTACATTCCC
CTGCACTGGCAGCACCTTTCGTGGGCAGTGGGCCCCGGCGTGAAGAATGCAAAGGAAATCGTCAACGTGATGGACTTCCC
GTACTTTGGCGACCTTGTAATAGAATAA

Upstream 100 bases:

>100_bases
TAGGCACCGCCGCCCCGGCAGACACCATGCCCGGCCGCCGCCCCCGCAGCGCACCCGGCCGAAATAGCATGGGAATCAAA
CATGTTACAAAAATGTCATT

Downstream 100 bases:

>100_bases
ACCGTCCATGTCGCGGAGCGGGCCGTCAGGTCCGCTCCGCTTTGTGCAAAGACGCTTTGTAGGGAAGGCAAACAACTCCT
GCTTGTTGTCCCCGCAAAGC

Product: oligopeptide/dipeptide ABC transporter periplasmic oligopeptide/dipeptide-binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 595; Mature: 594

Protein sequence:

>595_residues
MTYQWHLKRKALDGGGVARFRWGDFSSAAPYPRTGDCGSAPAKQGTAFMQNFIWRYWMKRVLKLMLLALVASLAFGCSAE
PEEKKAESAPAEKAAEAPKAEKKVLHLAMDADPVSLDPHVQLSGGMLQYSHLVFDPLVRWTQDMAFEPRLAEKYERIDPL
TMRFHLRKGVKFHSGNEFTAKDVVWTLARLKKSQDYKALFEPFAEPKIIDDYTIDLITHKPYPLMLNMATYIFPMDSKFY
SGNDENGQPKDAIVKTGPSFANVNESGTGPFTVESREQGVRMVFKAFPGYWGPRGNVEEIDLKPIKNDATRVASILSGDV
DFIMPVPPQDYDRLANHETVKLITMAGSRLITLQMNQNRVEAFKDPRVRQAVVYATDNQGIAEKIMKGRATAAGQQSPEG
FYSYVPELAPRYDLEKAKQLMKEAGYEKGFEVTMIAPNNRYVNDEKVAEAFVSMMAKIGITVNLKTMPKAQYWDEFDAQV
ADIQMVGWHPDTEDSANYTEFLLMCPNKETGYGQYNSGNYCNKKVDELTIASQSETDKAKRTALLQEAEKIIYEEAAYIP
LHWQHLSWAVGPGVKNAKEIVNVMDFPYFGDLVIE

Sequences:

>Translated_595_residues
MTYQWHLKRKALDGGGVARFRWGDFSSAAPYPRTGDCGSAPAKQGTAFMQNFIWRYWMKRVLKLMLLALVASLAFGCSAE
PEEKKAESAPAEKAAEAPKAEKKVLHLAMDADPVSLDPHVQLSGGMLQYSHLVFDPLVRWTQDMAFEPRLAEKYERIDPL
TMRFHLRKGVKFHSGNEFTAKDVVWTLARLKKSQDYKALFEPFAEPKIIDDYTIDLITHKPYPLMLNMATYIFPMDSKFY
SGNDENGQPKDAIVKTGPSFANVNESGTGPFTVESREQGVRMVFKAFPGYWGPRGNVEEIDLKPIKNDATRVASILSGDV
DFIMPVPPQDYDRLANHETVKLITMAGSRLITLQMNQNRVEAFKDPRVRQAVVYATDNQGIAEKIMKGRATAAGQQSPEG
FYSYVPELAPRYDLEKAKQLMKEAGYEKGFEVTMIAPNNRYVNDEKVAEAFVSMMAKIGITVNLKTMPKAQYWDEFDAQV
ADIQMVGWHPDTEDSANYTEFLLMCPNKETGYGQYNSGNYCNKKVDELTIASQSETDKAKRTALLQEAEKIIYEEAAYIP
LHWQHLSWAVGPGVKNAKEIVNVMDFPYFGDLVIE
>Mature_594_residues
TYQWHLKRKALDGGGVARFRWGDFSSAAPYPRTGDCGSAPAKQGTAFMQNFIWRYWMKRVLKLMLLALVASLAFGCSAEP
EEKKAESAPAEKAAEAPKAEKKVLHLAMDADPVSLDPHVQLSGGMLQYSHLVFDPLVRWTQDMAFEPRLAEKYERIDPLT
MRFHLRKGVKFHSGNEFTAKDVVWTLARLKKSQDYKALFEPFAEPKIIDDYTIDLITHKPYPLMLNMATYIFPMDSKFYS
GNDENGQPKDAIVKTGPSFANVNESGTGPFTVESREQGVRMVFKAFPGYWGPRGNVEEIDLKPIKNDATRVASILSGDVD
FIMPVPPQDYDRLANHETVKLITMAGSRLITLQMNQNRVEAFKDPRVRQAVVYATDNQGIAEKIMKGRATAAGQQSPEGF
YSYVPELAPRYDLEKAKQLMKEAGYEKGFEVTMIAPNNRYVNDEKVAEAFVSMMAKIGITVNLKTMPKAQYWDEFDAQVA
DIQMVGWHPDTEDSANYTEFLLMCPNKETGYGQYNSGNYCNKKVDELTIASQSETDKAKRTALLQEAEKIIYEEAAYIPL
HWQHLSWAVGPGVKNAKEIVNVMDFPYFGDLVIE

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=490, Percent_Identity=28.5714285714286, Blast_Score=170, Evalue=2e-43,
Organism=Escherichia coli, GI1787052, Length=468, Percent_Identity=25.2136752136752, Blast_Score=135, Evalue=7e-33,
Organism=Escherichia coli, GI1787762, Length=533, Percent_Identity=25.703564727955, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI1789397, Length=538, Percent_Identity=24.7211895910781, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI87081878, Length=523, Percent_Identity=22.3709369024857, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787495, Length=503, Percent_Identity=24.2544731610338, Blast_Score=96, Evalue=7e-21,
Organism=Escherichia coli, GI1787551, Length=439, Percent_Identity=21.6400911161731, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1789887, Length=551, Percent_Identity=22.1415607985481, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 67148; Mature: 67017

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: PS01040 SBP_BACTERIAL_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYQWHLKRKALDGGGVARFRWGDFSSAAPYPRTGDCGSAPAKQGTAFMQNFIWRYWMKR
CCEEEEEHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
VLKLMLLALVASLAFGCSAEPEEKKAESAPAEKAAEAPKAEKKVLHLAMDADPVSLDPHV
HHHHHHHHHHHHHHCCCCCCCHHHHHHCCCHHHHHCCCCHHHHEEEEEECCCCCCCCCCE
QLSGGMLQYSHLVFDPLVRWTQDMAFEPRLAEKYERIDPLTMRFHLRKGVKFHSGNEFTA
EECCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHEEHHHHCCCEECCCCCCCH
KDVVWTLARLKKSQDYKALFEPFAEPKIIDDYTIDLITHKPYPLMLNMATYIFPMDSKFY
HHHHHHHHHHHCCCCHHHHHHHCCCCEEECCEEEEEEECCCCCEEEEEEHHEEECCCCEE
SGNDENGQPKDAIVKTGPSFANVNESGTGPFTVESREQGVRMVFKAFPGYWGPRGNVEEI
CCCCCCCCCCHHHEECCCCCCCCCCCCCCCEEECCHHHHHHHHHHHCCCCCCCCCCCCEE
DLKPIKNDATRVASILSGDVDFIMPVPPQDYDRLANHETVKLITMAGSRLITLQMNQNRV
ECCCCCCHHHHHHHHHCCCCCEEECCCCCHHHHHCCCCEEEEEEECCCEEEEEEECCCHH
EAFKDPRVRQAVVYATDNQGIAEKIMKGRATAAGQQSPEGFYSYVPELAPRYDLEKAKQL
HHHCCCCCEEEEEEEECCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHH
MKEAGYEKGFEVTMIAPNNRYVNDEKVAEAFVSMMAKIGITVNLKTMPKAQYWDEFDAQV
HHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHCCEE
ADIQMVGWHPDTEDSANYTEFLLMCPNKETGYGQYNSGNYCNKKVDELTIASQSETDKAK
EEEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHEEECCCCCHHHHH
RTALLQEAEKIIYEEAAYIPLHWQHLSWAVGPGVKNAKEIVNVMDFPYFGDLVIE
HHHHHHHHHHHHHHCCCCCEEEEHHCCEECCCCCCCHHHHHHHHCCCCCCCEEEC
>Mature Secondary Structure 
TYQWHLKRKALDGGGVARFRWGDFSSAAPYPRTGDCGSAPAKQGTAFMQNFIWRYWMKR
CEEEEEHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
VLKLMLLALVASLAFGCSAEPEEKKAESAPAEKAAEAPKAEKKVLHLAMDADPVSLDPHV
HHHHHHHHHHHHHHCCCCCCCHHHHHHCCCHHHHHCCCCHHHHEEEEEECCCCCCCCCCE
QLSGGMLQYSHLVFDPLVRWTQDMAFEPRLAEKYERIDPLTMRFHLRKGVKFHSGNEFTA
EECCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHEEHHHHCCCEECCCCCCCH
KDVVWTLARLKKSQDYKALFEPFAEPKIIDDYTIDLITHKPYPLMLNMATYIFPMDSKFY
HHHHHHHHHHHCCCCHHHHHHHCCCCEEECCEEEEEEECCCCCEEEEEEHHEEECCCCEE
SGNDENGQPKDAIVKTGPSFANVNESGTGPFTVESREQGVRMVFKAFPGYWGPRGNVEEI
CCCCCCCCCCHHHEECCCCCCCCCCCCCCCEEECCHHHHHHHHHHHCCCCCCCCCCCCEE
DLKPIKNDATRVASILSGDVDFIMPVPPQDYDRLANHETVKLITMAGSRLITLQMNQNRV
ECCCCCCHHHHHHHHHCCCCCEEECCCCCHHHHHCCCCEEEEEEECCCEEEEEEECCCHH
EAFKDPRVRQAVVYATDNQGIAEKIMKGRATAAGQQSPEGFYSYVPELAPRYDLEKAKQL
HHHCCCCCEEEEEEEECCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHH
MKEAGYEKGFEVTMIAPNNRYVNDEKVAEAFVSMMAKIGITVNLKTMPKAQYWDEFDAQV
HHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHCCEE
ADIQMVGWHPDTEDSANYTEFLLMCPNKETGYGQYNSGNYCNKKVDELTIASQSETDKAK
EEEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHEEECCCCCHHHHH
RTALLQEAEKIIYEEAAYIPLHWQHLSWAVGPGVKNAKEIVNVMDFPYFGDLVIE
HHHHHHHHHHHHHHCCCCCEEEEHHCCEECCCCCCCHHHHHHHHCCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]