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The map label for this gene is surA [H]

Identifier: 78224732

GI number: 78224732

Start: 3983876

End: 3984877

Strand: Direct

Name: surA [H]

Synonym: Gmet_3549

Alternate gene names: 78224732

Gene position: 3983876-3984877 (Clockwise)

Preceding gene: 78224731

Following gene: 78224734

Centisome position: 99.66

GC content: 60.58

Gene sequence:

>1002_bases
ATGATCAAAACCCTCATCACAGCCACCCTTGTCCTTATCGCCACCCTTCCCTCACCGTCACACGCAGAGGTGGTCAACCG
GATTCTTGCCGTCGTCAACGACGAAATCATCACCTCCTACGCGGTCGAGAAGGAAAAGGCCACTATCCTCAAAGAGGCTG
AGCGCCAGCAGCCTCCGCCCCCCCCTGAATCCCTCGTCCATCTGGACGAGACGGCCCTTAACCGCCTCATCGACAAGAAG
CTCGTGGAGCAGAAAGTCCGGGAGCTGGACATCAAGGTAAGCGAAGAGGAAGTCCGGCAGGCCATCGAGGACGTGAAGCG
GCAGAACAAGCTCTCCCAGGAGTCCCTCGTATCGGCCCTGGCCAATCAGGGGCTCTCCTTCGACCAGTACAAGGTCCAGA
TCCGCGAACAGCTGGAGCGGCTGCGCCTTGTAAGCCAGGAGGTGCGGTCGAAGATCCAGGTCGGTGAACGGGAGATGCGG
GAGTACTACGAGGCGAACCCCGGCCGGTTTGGCGGCGAGGAGAACTTCCGGGCCCGCAACATCTACTTCAAGCTCGATGA
AAAGATGCCGGCCGACCAGGTGAAGAAGATCATGACCACCGCCCTGACCGTCCTCCACGAGGCCCGTGACGGCAAGGACT
TTGCCGAACTGGCCCGCCAGCACTCAGACGACCCTGCGGCAAAGAATACCGGTGGCGATCTGGGAACCTTCCGCAAGGGG
GACATCCTCCCCGAATTCGAGGAGAGCCTCATAAAGATGAAGCCGGGCGAGGTGAGCGACCTCATCTATGTCTCGGGGGG
GCTCCACATCGTCAAGCTGGAGGCACGCTTCGCCGGCACACCGAAACCCTTCGAACAGGTCAAGGCCGAAGTGGAGGACA
TCCTCTACCGGAAAAAGTCGGAAGAGCGCTTCAACCAGTGGGTGGCCGACCTCCGCAAGGGGGCGGCCATAGAGATTAGA
CAGGAAACGGGGACCGGGGACCGGGGACCAGCAAAACCGTAA

Upstream 100 bases:

>100_bases
CCCCGAGAGCACTCCGGCAAAGAAAGCGGAAACGAAGTAAGCGCACCGGGGCTGCCGGCAGCAACGTCGGCAGCCCCGTG
CCCCCTCCCCAACGGAAACC

Downstream 100 bases:

>100_bases
ACCAACCTCCACCCGCTTCTCGCCGACTTTTGGTTCGGATGCTCTTGACGTTTTTCTTCGCTTTTACCGATCCCTGGTCC
CCGGTCCCGGCCTTTACAGC

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase surA; PPIase surA; Rotamase surA [H]

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MIKTLITATLVLIATLPSPSHAEVVNRILAVVNDEIITSYAVEKEKATILKEAERQQPPPPPESLVHLDETALNRLIDKK
LVEQKVRELDIKVSEEEVRQAIEDVKRQNKLSQESLVSALANQGLSFDQYKVQIREQLERLRLVSQEVRSKIQVGEREMR
EYYEANPGRFGGEENFRARNIYFKLDEKMPADQVKKIMTTALTVLHEARDGKDFAELARQHSDDPAAKNTGGDLGTFRKG
DILPEFEESLIKMKPGEVSDLIYVSGGLHIVKLEARFAGTPKPFEQVKAEVEDILYRKKSEERFNQWVADLRKGAAIEIR
QETGTGDRGPAKP

Sequences:

>Translated_333_residues
MIKTLITATLVLIATLPSPSHAEVVNRILAVVNDEIITSYAVEKEKATILKEAERQQPPPPPESLVHLDETALNRLIDKK
LVEQKVRELDIKVSEEEVRQAIEDVKRQNKLSQESLVSALANQGLSFDQYKVQIREQLERLRLVSQEVRSKIQVGEREMR
EYYEANPGRFGGEENFRARNIYFKLDEKMPADQVKKIMTTALTVLHEARDGKDFAELARQHSDDPAAKNTGGDLGTFRKG
DILPEFEESLIKMKPGEVSDLIYVSGGLHIVKLEARFAGTPKPFEQVKAEVEDILYRKKSEERFNQWVADLRKGAAIEIR
QETGTGDRGPAKP
>Mature_333_residues
MIKTLITATLVLIATLPSPSHAEVVNRILAVVNDEIITSYAVEKEKATILKEAERQQPPPPPESLVHLDETALNRLIDKK
LVEQKVRELDIKVSEEEVRQAIEDVKRQNKLSQESLVSALANQGLSFDQYKVQIREQLERLRLVSQEVRSKIQVGEREMR
EYYEANPGRFGGEENFRARNIYFKLDEKMPADQVKKIMTTALTVLHEARDGKDFAELARQHSDDPAAKNTGGDLGTFRKG
DILPEFEESLIKMKPGEVSDLIYVSGGLHIVKLEARFAGTPKPFEQVKAEVEDILYRKKSEERFNQWVADLRKGAAIEIR
QETGTGDRGPAKP

Specific function: Chaperone involved in the correct folding and assembly of outer membrane proteins. It recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasm. Note=Is capable of associating with the outer membrane (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PpiC domains [H]

Homologues:

Organism=Escherichia coli, GI1786238, Length=301, Percent_Identity=27.2425249169435, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1786645, Length=306, Percent_Identity=28.4313725490196, Blast_Score=79, Evalue=4e-16,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR023034
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 37696; Mature: 37696

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKTLITATLVLIATLPSPSHAEVVNRILAVVNDEIITSYAVEKEKATILKEAERQQPPP
CHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PPESLVHLDETALNRLIDKKLVEQKVRELDIKVSEEEVRQAIEDVKRQNKLSQESLVSAL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHH
ANQGLSFDQYKVQIREQLERLRLVSQEVRSKIQVGEREMREYYEANPGRFGGEENFRARN
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEE
IYFKLDEKMPADQVKKIMTTALTVLHEARDGKDFAELARQHSDDPAAKNTGGDLGTFRKG
EEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
DILPEFEESLIKMKPGEVSDLIYVSGGLHIVKLEARFAGTPKPFEQVKAEVEDILYRKKS
CCCCHHHHHHHHCCCCCCCCEEEEECCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHH
EERFNQWVADLRKGAAIEIRQETGTGDRGPAKP
HHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MIKTLITATLVLIATLPSPSHAEVVNRILAVVNDEIITSYAVEKEKATILKEAERQQPPP
CHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PPESLVHLDETALNRLIDKKLVEQKVRELDIKVSEEEVRQAIEDVKRQNKLSQESLVSAL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHH
ANQGLSFDQYKVQIREQLERLRLVSQEVRSKIQVGEREMREYYEANPGRFGGEENFRARN
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEE
IYFKLDEKMPADQVKKIMTTALTVLHEARDGKDFAELARQHSDDPAAKNTGGDLGTFRKG
EEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
DILPEFEESLIKMKPGEVSDLIYVSGGLHIVKLEARFAGTPKPFEQVKAEVEDILYRKKS
CCCCHHHHHHHHCCCCCCCCEEEEECCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHH
EERFNQWVADLRKGAAIEIRQETGTGDRGPAKP
HHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA