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The map label for this gene is atpH

Identifier: 78224599

GI number: 78224599

Start: 3824696

End: 3825238

Strand: Reverse

Name: atpH

Synonym: Gmet_3409

Alternate gene names: 78224599

Gene position: 3825238-3824696 (Counterclockwise)

Preceding gene: 78224600

Following gene: 78224598

Centisome position: 95.69

GC content: 58.93

Gene sequence:

>543_bases
TTGATCTCGAACGCTATTGCACGTCGCTACGCCAAGGCGCTGGTGCAGCTCGGGGCCGAGGAAGACGCGGTCGACCGGTT
CGGTGCCGAGTTGGGGCAGTTCGCAGCCCTGCTTGAAGGAAACGCCGACATCGATTCCGTCTTGAAAAGCCCTGCGTACC
GCATTGAAGCCAAGAGGGAAATTCTCAAGGACGTTCTTGCGAAGTTGAGCCTCTCCGGCACGGTCTCCAACTTTCTCCAG
GTTCTCCTCGACCGGGGGAGAATCAGTTTCCTTCCCCAGATTGCCCACAGCTATGCCGCATTCGCCGACGAGCTTTCCGG
CGTCATTCGCCCGGTGCTCACTTCGGCTTTCCCTCTTGAGGATGCCCAGGTGGAGAGCATGAAGGGCGCGCTGGTCAAGG
CAACGGGGAAGAAGGTGCAGCTGTCGGTCCAGGTGGAGCCCTCGCTCATCGGCGGGGTGATCACCAAGATCGGCGACAAG
GTTTTTGACGGCAGCGTACGGACCCAGTTGAACAGGATTCAGGATATATTACAGAAGGGGTGA

Upstream 100 bases:

>100_bases
TTGCCGTTCAGATGGCTGAGCAGTCACTGCGCGAGAACATCAAGAAAGACGACCAGGATCGGCTGGTTAACGACTATCTT
ACGAAGGTGGAGAACTTACA

Downstream 100 bases:

>100_bases
GAGGTTCCATGGAAATCAGAGCCGAAGAAATCAGCGAAATTATCCGCAAGCAGATCAAGGAGTACGGCAAGGAGGTCGAG
GTGGCCGAGACCGGCACCAT

Product: F0F1 ATP synthase subunit delta

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F(1) sector subunit delta; F-type ATPase subunit delta; F-ATPase subunit delta

Number of amino acids: Translated: 180; Mature: 180

Protein sequence:

>180_residues
MISNAIARRYAKALVQLGAEEDAVDRFGAELGQFAALLEGNADIDSVLKSPAYRIEAKREILKDVLAKLSLSGTVSNFLQ
VLLDRGRISFLPQIAHSYAAFADELSGVIRPVLTSAFPLEDAQVESMKGALVKATGKKVQLSVQVEPSLIGGVITKIGDK
VFDGSVRTQLNRIQDILQKG

Sequences:

>Translated_180_residues
MISNAIARRYAKALVQLGAEEDAVDRFGAELGQFAALLEGNADIDSVLKSPAYRIEAKREILKDVLAKLSLSGTVSNFLQ
VLLDRGRISFLPQIAHSYAAFADELSGVIRPVLTSAFPLEDAQVESMKGALVKATGKKVQLSVQVEPSLIGGVITKIGDK
VFDGSVRTQLNRIQDILQKG
>Mature_180_residues
MISNAIARRYAKALVQLGAEEDAVDRFGAELGQFAALLEGNADIDSVLKSPAYRIEAKREILKDVLAKLSLSGTVSNFLQ
VLLDRGRISFLPQIAHSYAAFADELSGVIRPVLTSAFPLEDAQVESMKGALVKATGKKVQLSVQVEPSLIGGVITKIGDK
VFDGSVRTQLNRIQDILQKG

Specific function: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction

COG id: COG0712

COG function: function code C; F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase delta chain family

Homologues:

Organism=Homo sapiens, GI4502303, Length=167, Percent_Identity=28.7425149700599, Blast_Score=76, Evalue=1e-14,
Organism=Escherichia coli, GI1790173, Length=173, Percent_Identity=30.635838150289, Blast_Score=72, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71984710, Length=171, Percent_Identity=26.3157894736842, Blast_Score=77, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71984717, Length=171, Percent_Identity=26.3157894736842, Blast_Score=77, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6320504, Length=174, Percent_Identity=26.4367816091954, Blast_Score=76, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24647054, Length=172, Percent_Identity=26.7441860465116, Blast_Score=70, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATPD_GEOMG (Q39Q53)

Other databases:

- EMBL:   CP000148
- RefSeq:   YP_386346.1
- ProteinModelPortal:   Q39Q53
- SMR:   Q39Q53
- STRING:   Q39Q53
- GeneID:   3741187
- GenomeReviews:   CP000148_GR
- KEGG:   gme:Gmet_3409
- NMPDR:   fig|269799.3.peg.3384
- eggNOG:   COG0712
- HOGENOM:   HBG668108
- OMA:   FIAICGE
- PhylomeDB:   Q39Q53
- ProtClustDB:   PRK13429
- BioCyc:   GMET269799:GMET_3409-MONOMER
- HAMAP:   MF_01416
- InterPro:   IPR000711
- Gene3D:   G3DSA:1.10.520.20
- PANTHER:   PTHR11910
- PRINTS:   PR00125
- TIGRFAMs:   TIGR01145

Pfam domain/function: PF00213 OSCP; SSF47928 ATPsynt_OSCP

EC number: 3.6.3.14

Molecular weight: Translated: 19381; Mature: 19381

Theoretical pI: Translated: 8.90; Mature: 8.90

Prosite motif: PS00389 ATPASE_DELTA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISNAIARRYAKALVQLGAEEDAVDRFGAELGQFAALLEGNADIDSVLKSPAYRIEAKRE
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHH
ILKDVLAKLSLSGTVSNFLQVLLDRGRISFLPQIAHSYAAFADELSGVIRPVLTSAFPLE
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DAQVESMKGALVKATGKKVQLSVQVEPSLIGGVITKIGDKVFDGSVRTQLNRIQDILQKG
HHHHHHHHHHHHEECCCEEEEEEEECHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MISNAIARRYAKALVQLGAEEDAVDRFGAELGQFAALLEGNADIDSVLKSPAYRIEAKRE
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHH
ILKDVLAKLSLSGTVSNFLQVLLDRGRISFLPQIAHSYAAFADELSGVIRPVLTSAFPLE
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DAQVESMKGALVKATGKKVQLSVQVEPSLIGGVITKIGDKVFDGSVRTQLNRIQDILQKG
HHHHHHHHHHHHEECCCEEEEEEEECHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA