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The map label for this gene is atpA

Identifier: 78224598

GI number: 78224598

Start: 3823176

End: 3824687

Strand: Reverse

Name: atpA

Synonym: Gmet_3408

Alternate gene names: 78224598

Gene position: 3824687-3823176 (Counterclockwise)

Preceding gene: 78224599

Following gene: 78224597

Centisome position: 95.68

GC content: 61.9

Gene sequence:

>1512_bases
ATGGAAATCAGAGCCGAAGAAATCAGCGAAATTATCCGCAAGCAGATCAAGGAGTACGGCAAGGAGGTCGAGGTGGCCGA
GACCGGCACCATCATCTCCGTCGGTGACGGTATCGCCCGCATCCACGGCCTGGACAAGGCCATGGCCGGCGAGCTCCTGG
AGTTCCCCGGCGGGGTCTCCGGCATGGTTCTCAACCTCGAAGAGGACAACGTCGGTGCGGCGATCCTCGGTGAAGACAAC
GAGAACATAAAGGAAGGGACCACCGTCAAGCGGACCGGCAGGATCGTCGAGGTTCCGGTTGGCGAGGCCCTCATCGGCCG
CGTTGTCAACGCCATTGGCCAACCCATTGACGGCAAGGGCCCCATCAACACCTCCACCTTCGGTAAGGTCGAGGTGAAGG
CCCCCGGCATCGTCAAGCGGAAGTCGGTCCACCAGCCGATGCAGACCGGCCTCAAGGCCATCGACGCCATGGTTCCGGTT
GGCCGCGGCCAGCGGGAGCTCATCATCGGCGACCGCCAGACCGGCAAGACCGCCGTTGCCATCGACACCATCATCAACCA
GAAGGGTGGCGACCTCATCTGTATCTACGTGGCCATCGGCCAGAAGCGTTCCACCGTTGCCCAGGTGGTGAGCAAGCTCC
AGGAGCACGGGGCGATGGATTACACCATCATTGTTTCCGCCTCCGCCTCCGAGCCTGCACCGCTCCAGTTCATCGCCCCC
TACACCGGCGTCACCATGGGCGAGTACTTCCGGGACAACGGCAAGCATGCCCTGATCATCTACGACGACCTCTCCAAGCA
GGCCGTCGCCTATCGCCAGCTTTCCCTGCTCCTTCGCCGTCCGCCGGGGCGTGAAGCCTATCCGGGCGACGTTTTCTACC
TCCACAGCCGCCTCCTCGAGCGTGCGGCGAAGCTCTCCGACGACTGCGGCGCAGGCTCCCTTACCGCGCTCCCGATCATC
GAGACCCAGGCTGGTGACGTTTCCGCCTATATTCCGACCAACGTCATCTCCATCACCGACGGTCAGATCTATCTGGAGAG
CGACCTGTTCTACTCCGGCGTCCGCCCGGCCATCAACGTCGGCCTCTCGGTCTCCCGGGTCGGTGGTTCCGCTCAGGTGA
AGGCCATGAAGCAGGTTGCCGGTACGCTCCGTCTGAACCTCGCCCAGTATCGCGAGATGGCAGCCTTTGCCCAGTTCGGT
TCCGACCTGGACAAGGCGACCCAGATGCAGCTGGCCCGTGGCGAGCGCCTCGTGGAGATTCTCAAGCAACCCCAGTACCG
TCCGATTCCCAACGAGAAACAGGTCCTCATCATCTTCGCCGCCAACAACGGCTACGTGGATGACTACCCCGTCGCCTCCC
TGCGCCGTTACGAGAGCGAGCTCTATTCCTTCTTCGATGGAAGGAAGGCCGATATCCTCGCCGAACTGCGCGACAAGAAG
GCGATCGATGACGACCTCAAGGGCAAGATTGTTGCCGCCCTTGACGAATTCAAGAAGGAATTTACCGCGTAA

Upstream 100 bases:

>100_bases
GCGGGGTGATCACCAAGATCGGCGACAAGGTTTTTGACGGCAGCGTACGGACCCAGTTGAACAGGATTCAGGATATATTA
CAGAAGGGGTGAGAGGTTCC

Downstream 100 bases:

>100_bases
TCTAAGGACGGTTCTCCCACTATGGCAAGCCTGAAAAGCATAAAAAAGCGTATTGTCTCGGTAAAAAACACCAGACAGAT
AACCAAGGCCATGAAGATGG

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha

Number of amino acids: Translated: 503; Mature: 503

Protein sequence:

>503_residues
MEIRAEEISEIIRKQIKEYGKEVEVAETGTIISVGDGIARIHGLDKAMAGELLEFPGGVSGMVLNLEEDNVGAAILGEDN
ENIKEGTTVKRTGRIVEVPVGEALIGRVVNAIGQPIDGKGPINTSTFGKVEVKAPGIVKRKSVHQPMQTGLKAIDAMVPV
GRGQRELIIGDRQTGKTAVAIDTIINQKGGDLICIYVAIGQKRSTVAQVVSKLQEHGAMDYTIIVSASASEPAPLQFIAP
YTGVTMGEYFRDNGKHALIIYDDLSKQAVAYRQLSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSDDCGAGSLTALPII
ETQAGDVSAYIPTNVISITDGQIYLESDLFYSGVRPAINVGLSVSRVGGSAQVKAMKQVAGTLRLNLAQYREMAAFAQFG
SDLDKATQMQLARGERLVEILKQPQYRPIPNEKQVLIIFAANNGYVDDYPVASLRRYESELYSFFDGRKADILAELRDKK
AIDDDLKGKIVAALDEFKKEFTA

Sequences:

>Translated_503_residues
MEIRAEEISEIIRKQIKEYGKEVEVAETGTIISVGDGIARIHGLDKAMAGELLEFPGGVSGMVLNLEEDNVGAAILGEDN
ENIKEGTTVKRTGRIVEVPVGEALIGRVVNAIGQPIDGKGPINTSTFGKVEVKAPGIVKRKSVHQPMQTGLKAIDAMVPV
GRGQRELIIGDRQTGKTAVAIDTIINQKGGDLICIYVAIGQKRSTVAQVVSKLQEHGAMDYTIIVSASASEPAPLQFIAP
YTGVTMGEYFRDNGKHALIIYDDLSKQAVAYRQLSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSDDCGAGSLTALPII
ETQAGDVSAYIPTNVISITDGQIYLESDLFYSGVRPAINVGLSVSRVGGSAQVKAMKQVAGTLRLNLAQYREMAAFAQFG
SDLDKATQMQLARGERLVEILKQPQYRPIPNEKQVLIIFAANNGYVDDYPVASLRRYESELYSFFDGRKADILAELRDKK
AIDDDLKGKIVAALDEFKKEFTA
>Mature_503_residues
MEIRAEEISEIIRKQIKEYGKEVEVAETGTIISVGDGIARIHGLDKAMAGELLEFPGGVSGMVLNLEEDNVGAAILGEDN
ENIKEGTTVKRTGRIVEVPVGEALIGRVVNAIGQPIDGKGPINTSTFGKVEVKAPGIVKRKSVHQPMQTGLKAIDAMVPV
GRGQRELIIGDRQTGKTAVAIDTIINQKGGDLICIYVAIGQKRSTVAQVVSKLQEHGAMDYTIIVSASASEPAPLQFIAP
YTGVTMGEYFRDNGKHALIIYDDLSKQAVAYRQLSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSDDCGAGSLTALPII
ETQAGDVSAYIPTNVISITDGQIYLESDLFYSGVRPAINVGLSVSRVGGSAQVKAMKQVAGTLRLNLAQYREMAAFAQFG
SDLDKATQMQLARGERLVEILKQPQYRPIPNEKQVLIIFAANNGYVDDYPVASLRRYESELYSFFDGRKADILAELRDKK
AIDDDLKGKIVAALDEFKKEFTA

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI50345984, Length=505, Percent_Identity=63.3663366336634, Blast_Score=639, Evalue=0.0,
Organism=Homo sapiens, GI4757810, Length=505, Percent_Identity=63.3663366336634, Blast_Score=639, Evalue=0.0,
Organism=Homo sapiens, GI19913428, Length=300, Percent_Identity=30, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI19913426, Length=300, Percent_Identity=29.3333333333333, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI32189394, Length=415, Percent_Identity=24.578313253012, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI19913424, Length=245, Percent_Identity=26.530612244898, Blast_Score=80, Evalue=3e-15,
Organism=Escherichia coli, GI1790172, Length=509, Percent_Identity=57.3673870333988, Blast_Score=602, Evalue=1e-173,
Organism=Escherichia coli, GI1788251, Length=324, Percent_Identity=28.7037037037037, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1790170, Length=357, Percent_Identity=25.2100840336134, Blast_Score=114, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI71988063, Length=504, Percent_Identity=63.0952380952381, Blast_Score=638, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71988080, Length=504, Percent_Identity=63.0952380952381, Blast_Score=636, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71988074, Length=504, Percent_Identity=58.9285714285714, Blast_Score=583, Evalue=1e-167,
Organism=Caenorhabditis elegans, GI17510931, Length=364, Percent_Identity=26.0989010989011, Blast_Score=122, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI17570191, Length=324, Percent_Identity=27.4691358024691, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI25144756, Length=367, Percent_Identity=25.3405994550409, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=72, Blast_Score=86, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17565854, Length=250, Percent_Identity=27.2, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI71988068, Length=73, Percent_Identity=42.4657534246575, Blast_Score=71, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319370, Length=503, Percent_Identity=62.8230616302187, Blast_Score=650, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319603, Length=336, Percent_Identity=27.9761904761905, Blast_Score=117, Evalue=4e-27,
Organism=Saccharomyces cerevisiae, GI6322581, Length=413, Percent_Identity=25.181598062954, Blast_Score=108, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6320016, Length=154, Percent_Identity=31.1688311688312, Blast_Score=64, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24658560, Length=506, Percent_Identity=62.0553359683794, Blast_Score=628, Evalue=1e-180,
Organism=Drosophila melanogaster, GI281361666, Length=301, Percent_Identity=28.5714285714286, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24646341, Length=301, Percent_Identity=28.5714285714286, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI17136796, Length=301, Percent_Identity=28.5714285714286, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24638766, Length=367, Percent_Identity=25.0681198910082, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI28574560, Length=405, Percent_Identity=24.6913580246914, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24583992, Length=371, Percent_Identity=26.1455525606469, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24583988, Length=264, Percent_Identity=26.5151515151515, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24583986, Length=264, Percent_Identity=26.5151515151515, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24583984, Length=264, Percent_Identity=26.5151515151515, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI20129479, Length=238, Percent_Identity=27.7310924369748, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPA_GEOMG (Q39Q54)

Other databases:

- EMBL:   CP000148
- RefSeq:   YP_386345.1
- ProteinModelPortal:   Q39Q54
- SMR:   Q39Q54
- STRING:   Q39Q54
- GeneID:   3741186
- GenomeReviews:   CP000148_GR
- KEGG:   gme:Gmet_3408
- NMPDR:   fig|269799.3.peg.3383
- eggNOG:   COG0056
- HOGENOM:   HBG565875
- OMA:   EMALTLW
- PhylomeDB:   Q39Q54
- ProtClustDB:   PRK09281
- BioCyc:   GMET269799:GMET_3408-MONOMER
- HAMAP:   MF_01346
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF3
- TIGRFAMs:   TIGR00962

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 54640; Mature: 54640

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIRAEEISEIIRKQIKEYGKEVEVAETGTIISVGDGIARIHGLDKAMAGELLEFPGGVS
CCCCHHHHHHHHHHHHHHHCCEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCC
GMVLNLEEDNVGAAILGEDNENIKEGTTVKRTGRIVEVPVGEALIGRVVNAIGQPIDGKG
EEEEEEECCCCCEEEECCCCCCCCCCCEEECCCCEEEECCCHHHHHHHHHHHCCCCCCCC
PINTSTFGKVEVKAPGIVKRKSVHQPMQTGLKAIDAMVPVGRGQRELIIGDRQTGKTAVA
CCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEE
IDTIINQKGGDLICIYVAIGQKRSTVAQVVSKLQEHGAMDYTIIVSASASEPAPLQFIAP
EEHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCEEEECC
YTGVTMGEYFRDNGKHALIIYDDLSKQAVAYRQLSLLLRRPPGREAYPGDVFYLHSRLLE
CCCCCHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
RAAKLSDDCGAGSLTALPIIETQAGDVSAYIPTNVISITDGQIYLESDLFYSGVRPAINV
HHHHCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEECCCHHCCCCHHHHC
GLSVSRVGGSAQVKAMKQVAGTLRLNLAQYREMAAFAQFGSDLDKATQMQLARGERLVEI
CEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LKQPQYRPIPNEKQVLIIFAANNGYVDDYPVASLRRYESELYSFFDGRKADILAELRDKK
HHCCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
AIDDDLKGKIVAALDEFKKEFTA
CCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEIRAEEISEIIRKQIKEYGKEVEVAETGTIISVGDGIARIHGLDKAMAGELLEFPGGVS
CCCCHHHHHHHHHHHHHHHCCEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCC
GMVLNLEEDNVGAAILGEDNENIKEGTTVKRTGRIVEVPVGEALIGRVVNAIGQPIDGKG
EEEEEEECCCCCEEEECCCCCCCCCCCEEECCCCEEEECCCHHHHHHHHHHHCCCCCCCC
PINTSTFGKVEVKAPGIVKRKSVHQPMQTGLKAIDAMVPVGRGQRELIIGDRQTGKTAVA
CCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEE
IDTIINQKGGDLICIYVAIGQKRSTVAQVVSKLQEHGAMDYTIIVSASASEPAPLQFIAP
EEHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCEEEECC
YTGVTMGEYFRDNGKHALIIYDDLSKQAVAYRQLSLLLRRPPGREAYPGDVFYLHSRLLE
CCCCCHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
RAAKLSDDCGAGSLTALPIIETQAGDVSAYIPTNVISITDGQIYLESDLFYSGVRPAINV
HHHHCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEECCCHHCCCCHHHHC
GLSVSRVGGSAQVKAMKQVAGTLRLNLAQYREMAAFAQFGSDLDKATQMQLARGERLVEI
CEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LKQPQYRPIPNEKQVLIIFAANNGYVDDYPVASLRRYESELYSFFDGRKADILAELRDKK
HHCCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
AIDDDLKGKIVAALDEFKKEFTA
CCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA