Click here to switch to the map view.

The map label for this gene is scoA [H]

Identifier: 78224487

GI number: 78224487

Start: 3709618

End: 3710307

Strand: Direct

Name: scoA [H]

Synonym: Gmet_3296

Alternate gene names: 78224487

Gene position: 3709618-3710307 (Clockwise)

Preceding gene: 78224486

Following gene: 78224488

Centisome position: 92.8

GC content: 61.88

Gene sequence:

>690_bases
ATGAAAGTTCAATCGTCCATAGAAAAGGCCCTGGAGGGGATCCAGGACGGGGCAACCCTCATGGTCGGCGGGTTCGGCCT
GGTGGGAATCCCCGAGAAGCTGATCCTCGGGCTCCGGGAAAAGGGGGTGAAGAATTTGACCGTCATCTCCAACAACTGCG
GGGTGGATGACTTCGGCTTGGGAATTCTGCTCCAGAACCGGCAAATCAGGAAGATGGTCTCCTCCTACGTGGGGGAAAAC
AAGGAATTCGAGCGCCAGTTCCTCTCCGGCGAGCTGGAGGTGGAGCTTACCCCCCAGGGGACTCTAGCGGAACGGATCAG
GGCCGGCGGCGCGGGAATCCCGGCTTTCTACACCCCGGCCGGCGTCGGCACCCCCCTGGCCGAGGGGCGCGAGGTGCGGA
GCTTCAACGGCCGGGAGTACCTCCTGGAGACAGGCCTTGTGGCCGACTTCGCCCTGGTGAAGGCGTGGAAGGGGGACTGG
ATGGGGAACCTCATCTACAACAAGACCTCCCGCAACTTCAATCCCATGATGGCCACGGCGGCAAAGGTCACCATCGCCGA
GGTTGAGGATCTTCTGGACCCCGGAGAGTTGGACCCGGCTTTCATTCACACACCCGGCGTCTATGTGCAGCGAATCGTGC
TGTGTGGCAACTACGAGAAGCGGATCGAGCGGCGGACTGTCCGGGCTTGA

Upstream 100 bases:

>100_bases
CCTGCCCCCCCGACCCGCACCCCGACTATTTCTGGTGTGCCTGGGAATTTACCCTGCGGGAGTCATAACGAAGTCCTCCG
GGAGAAAGGGAGAACGTGCA

Downstream 100 bases:

>100_bases
TTGAAAGGAGAGAAACAATGGCTTTGACACGGGAACAGCTGGCCCAGCGGGCAGCACAGGAGGTTGAAGACGGCTTTTAC
GTGAACCTGGGGATCGGCAT

Product: 3-oxoacid CoA-transferase subunit A

Products: NA

Alternate protein names: Succinyl CoA:3-oxoacid CoA-transferase; OXCT A [H]

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MKVQSSIEKALEGIQDGATLMVGGFGLVGIPEKLILGLREKGVKNLTVISNNCGVDDFGLGILLQNRQIRKMVSSYVGEN
KEFERQFLSGELEVELTPQGTLAERIRAGGAGIPAFYTPAGVGTPLAEGREVRSFNGREYLLETGLVADFALVKAWKGDW
MGNLIYNKTSRNFNPMMATAAKVTIAEVEDLLDPGELDPAFIHTPGVYVQRIVLCGNYEKRIERRTVRA

Sequences:

>Translated_229_residues
MKVQSSIEKALEGIQDGATLMVGGFGLVGIPEKLILGLREKGVKNLTVISNNCGVDDFGLGILLQNRQIRKMVSSYVGEN
KEFERQFLSGELEVELTPQGTLAERIRAGGAGIPAFYTPAGVGTPLAEGREVRSFNGREYLLETGLVADFALVKAWKGDW
MGNLIYNKTSRNFNPMMATAAKVTIAEVEDLLDPGELDPAFIHTPGVYVQRIVLCGNYEKRIERRTVRA
>Mature_229_residues
MKVQSSIEKALEGIQDGATLMVGGFGLVGIPEKLILGLREKGVKNLTVISNNCGVDDFGLGILLQNRQIRKMVSSYVGEN
KEFERQFLSGELEVELTPQGTLAERIRAGGAGIPAFYTPAGVGTPLAEGREVRSFNGREYLLETGLVADFALVKAWKGDW
MGNLIYNKTSRNFNPMMATAAKVTIAEVEDLLDPGELDPAFIHTPGVYVQRIVLCGNYEKRIERRTVRA

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=238, Percent_Identity=58.4033613445378, Blast_Score=282, Evalue=2e-76,
Organism=Homo sapiens, GI11545841, Length=235, Percent_Identity=54.8936170212766, Blast_Score=247, Evalue=7e-66,
Organism=Escherichia coli, GI1788551, Length=209, Percent_Identity=44.4976076555024, Blast_Score=196, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI17531517, Length=243, Percent_Identity=53.0864197530864, Blast_Score=261, Evalue=1e-70,
Organism=Drosophila melanogaster, GI21358325, Length=241, Percent_Identity=53.1120331950208, Blast_Score=263, Evalue=9e-71,
Organism=Drosophila melanogaster, GI24655794, Length=241, Percent_Identity=53.1120331950208, Blast_Score=262, Evalue=1e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.5 [H]

Molecular weight: Translated: 25077; Mature: 25077

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: PS01273 COA_TRANSF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVQSSIEKALEGIQDGATLMVGGFGLVGIPEKLILGLREKGVKNLTVISNNCGVDDFGL
CCCHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCC
GILLQNRQIRKMVSSYVGENKEFERQFLSGELEVELTPQGTLAERIRAGGAGIPAFYTPA
EEEECCHHHHHHHHHHHCCCHHHHHHHHCCCEEEEECCCCHHHHHHHCCCCCCCCEECCC
GVGTPLAEGREVRSFNGREYLLETGLVADFALVKAWKGDWMGNLIYNKTSRNFNPMMATA
CCCCCCCCCCHHHCCCCCHHHHHHCHHHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHH
AKVTIAEVEDLLDPGELDPAFIHTPGVYVQRIVLCGNYEKRIERRTVRA
HHHHHHHHHHHCCCCCCCCCEEECCCHHHHHHHHCCCHHHHHHHHHCCC
>Mature Secondary Structure
MKVQSSIEKALEGIQDGATLMVGGFGLVGIPEKLILGLREKGVKNLTVISNNCGVDDFGL
CCCHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCC
GILLQNRQIRKMVSSYVGENKEFERQFLSGELEVELTPQGTLAERIRAGGAGIPAFYTPA
EEEECCHHHHHHHHHHHCCCHHHHHHHHCCCEEEEECCCCHHHHHHHCCCCCCCCEECCC
GVGTPLAEGREVRSFNGREYLLETGLVADFALVKAWKGDWMGNLIYNKTSRNFNPMMATA
CCCCCCCCCCHHHCCCCCHHHHHHCHHHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHH
AKVTIAEVEDLLDPGELDPAFIHTPGVYVQRIVLCGNYEKRIERRTVRA
HHHHHHHHHHHCCCCCCCCCEEECCCHHHHHHHHCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969509; 9384377 [H]