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The map label for this gene is scoB [H]

Identifier: 78224488

GI number: 78224488

Start: 3710325

End: 3710981

Strand: Direct

Name: scoB [H]

Synonym: Gmet_3297

Alternate gene names: 78224488

Gene position: 3710325-3710981 (Clockwise)

Preceding gene: 78224487

Following gene: 78224489

Centisome position: 92.82

GC content: 63.32

Gene sequence:

>657_bases
ATGGCTTTGACACGGGAACAGCTGGCCCAGCGGGCAGCACAGGAGGTTGAAGACGGCTTTTACGTGAACCTGGGGATCGG
CATCCCCACCATGGTTGCGAACTACATCCCCCCTGCCTGTCACGTGGTCCTGCAGTCGGAGAACGGCCTCCTGGGGATCG
GCCCGTCCCCCCGCGAGGACGAGGTGGACCCGGAGCTGATCAATGCCGGCAAGGAGACCATCACCATGATTCCCGGCGCC
TGCATCTTCAGCAGTTCCGACTCCTTCGCCATGATCCGGGGTGGGCACATCGACCTGGCCATCCTCGGGGGGATGGAGGT
TTCGGACTCCGGCGACCTGGCGAACTGGATGATCCCCGGAAAGATGGTGAAGGGAATGGGGGGAGCCATGGACCTGGTCC
ACGGGGCGAAGAAGATCGTGGTGGTCATGGAGCACTGCAGCAAGGGGGGGCAGTCCAAGATCCTGAAGCAGTGCACCCTC
CCCCTCACCGGCAAGGGAGTAGTGAACCGGATCATCACCGACCTGGCAGTGATGGATGTCACTGGCGACGGTCTCATCCT
CCGGGAACTGGCACCGGAGGTGAGCGTCGACGATGTGGTCCGGGCAACGGAAGCGTCGCTTGCCGTGCCCGCCGACGTAG
GAACGATGGCCCTGTAA

Upstream 100 bases:

>100_bases
ACACACCCGGCGTCTATGTGCAGCGAATCGTGCTGTGTGGCAACTACGAGAAGCGGATCGAGCGGCGGACTGTCCGGGCT
TGATTGAAAGGAGAGAAACA

Downstream 100 bases:

>100_bases
CCGCGCAATCCCCGACGGGAAAGGAGCAACTCAATGAAAGCATGTCCCCTGGCCGTAATCCTTGTCCTCCTTCTCCTCGC
GGGGTGCGCGGGAAGCCGTC

Product: butyryl-CoA:acetate CoA transferase

Products: NA

Alternate protein names: OXCT B; Succinyl CoA:3-oxoacid CoA-transferase [H]

Number of amino acids: Translated: 218; Mature: 217

Protein sequence:

>218_residues
MALTREQLAQRAAQEVEDGFYVNLGIGIPTMVANYIPPACHVVLQSENGLLGIGPSPREDEVDPELINAGKETITMIPGA
CIFSSSDSFAMIRGGHIDLAILGGMEVSDSGDLANWMIPGKMVKGMGGAMDLVHGAKKIVVVMEHCSKGGQSKILKQCTL
PLTGKGVVNRIITDLAVMDVTGDGLILRELAPEVSVDDVVRATEASLAVPADVGTMAL

Sequences:

>Translated_218_residues
MALTREQLAQRAAQEVEDGFYVNLGIGIPTMVANYIPPACHVVLQSENGLLGIGPSPREDEVDPELINAGKETITMIPGA
CIFSSSDSFAMIRGGHIDLAILGGMEVSDSGDLANWMIPGKMVKGMGGAMDLVHGAKKIVVVMEHCSKGGQSKILKQCTL
PLTGKGVVNRIITDLAVMDVTGDGLILRELAPEVSVDDVVRATEASLAVPADVGTMAL
>Mature_217_residues
ALTREQLAQRAAQEVEDGFYVNLGIGIPTMVANYIPPACHVVLQSENGLLGIGPSPREDEVDPELINAGKETITMIPGAC
IFSSSDSFAMIRGGHIDLAILGGMEVSDSGDLANWMIPGKMVKGMGGAMDLVHGAKKIVVVMEHCSKGGQSKILKQCTLP
LTGKGVVNRIITDLAVMDVTGDGLILRELAPEVSVDDVVRATEASLAVPADVGTMAL

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG2057

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit B family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=207, Percent_Identity=63.2850241545894, Blast_Score=262, Evalue=2e-70,
Organism=Homo sapiens, GI11545841, Length=214, Percent_Identity=57.9439252336449, Blast_Score=253, Evalue=1e-67,
Organism=Escherichia coli, GI1788552, Length=211, Percent_Identity=50.2369668246445, Blast_Score=223, Evalue=5e-60,
Organism=Caenorhabditis elegans, GI17531517, Length=215, Percent_Identity=56.2790697674419, Blast_Score=244, Evalue=4e-65,
Organism=Drosophila melanogaster, GI21358325, Length=214, Percent_Identity=57.9439252336449, Blast_Score=255, Evalue=2e-68,
Organism=Drosophila melanogaster, GI24655794, Length=214, Percent_Identity=57.9439252336449, Blast_Score=254, Evalue=2e-68,

Paralogues:

None

Copy number: 369 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012791
- InterPro:   IPR004165
- InterPro:   IPR004164 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.5 [H]

Molecular weight: Translated: 22838; Mature: 22707

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: PS01274 COA_TRANSF_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALTREQLAQRAAQEVEDGFYVNLGIGIPTMVANYIPPACHVVLQSENGLLGIGPSPRED
CCCCHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHCCCEEEEEEECCCCEEECCCCCCCC
EVDPELINAGKETITMIPGACIFSSSDSFAMIRGGHIDLAILGGMEVSDSGDLANWMIPG
CCCHHHHHCCCCEEEECCCEEEECCCCCEEEEECCCEEEEEECCEEECCCCCCEEEECCH
KMVKGMGGAMDLVHGAKKIVVVMEHCSKGGQSKILKQCTLPLTGKGVVNRIITDLAVMDV
HHHHCCCCHHHHHHCHHHHEEEEHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHEEE
TGDGLILRELAPEVSVDDVVRATEASLAVPADVGTMAL
CCCCEEHHHHCCCCCHHHHHHHHHCCEECCCCCCCCCC
>Mature Secondary Structure 
ALTREQLAQRAAQEVEDGFYVNLGIGIPTMVANYIPPACHVVLQSENGLLGIGPSPRED
CCCHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHCCCEEEEEEECCCCEEECCCCCCCC
EVDPELINAGKETITMIPGACIFSSSDSFAMIRGGHIDLAILGGMEVSDSGDLANWMIPG
CCCHHHHHCCCCEEEECCCEEEECCCCCEEEEECCCEEEEEECCEEECCCCCCEEEECCH
KMVKGMGGAMDLVHGAKKIVVVMEHCSKGGQSKILKQCTLPLTGKGVVNRIITDLAVMDV
HHHHCCCCHHHHHHCHHHHEEEEHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHEEE
TGDGLILRELAPEVSVDDVVRATEASLAVPADVGTMAL
CCCCEEHHHHCCCCCHHHHHHHHHCCEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]