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The map label for this gene is crt [H]

Identifier: 78224475

GI number: 78224475

Start: 3694109

End: 3694927

Strand: Direct

Name: crt [H]

Synonym: Gmet_3284

Alternate gene names: 78224475

Gene position: 3694109-3694927 (Clockwise)

Preceding gene: 78224470

Following gene: 78224476

Centisome position: 92.41

GC content: 58.24

Gene sequence:

>819_bases
ATGACAATGGCAATGCCACAACTGACCGATGCGACCCTTGAACTTTCAGAGCGAGTGGCGCTCCTTACTTTTTGCCGTAA
CGACGTGCGCAACGCCCTGACGGGAACCACCCTGGTGGATGACATCCTAGCGACCCTCGATTGGGCCAACCGGACACCGG
AGGTATCGGTGCTGGTAATGACCGGCGAGGGAGCAGCATTTTCTAGCGGTGGCAACGTGAAGGAGATGAGGGACCGGCAG
GGAATCTTCAGCGGCTCTTCCATGACCATCCAGGATCAATACCGTCGCGGGATCCAGCGGATTCCTCTGGCCATGGAACG
GGCAGAGATTCCCCTTATTGCGTCGGTGAACGGCCCCGCCATTGGCGCAGGATTCGATCTCGCCTGCATGTGCGACATTC
GCATCGGCTCATCGGAAGCAGTTGTCGGTGAGACCTTCATCAATCTAGGTATCATCCCCGGCGACGGGGGGGCTTGGTTC
CTCCAACGGCTTGTGGGGTATCAGCGGGCAGCTGAACTTACCTTTACAGGGCGTCTAGTGGATGCCACAGAAGCGCTGAA
GCTTGGGATATTTCTGGAGGTGACCGAACCGACCCAGCTCATACCACGGTCTCATGAGCTGGCGAGCCGCATCGCCAGCA
AATCCCCCCATGCCGTACGCATGACCAAGCGGCTTATGAAACATGCCCAGCGGGGAGATCTGGCCGATTTCCTCGATCTG
TGCGCCTGTTTCCAAGGGATGGCGCACCATACCGACGATCACCGAGAGGCCATCAATGCCTTCCTCGAAAAAAGGGCTCC
CGTCTATGCAGGCAGGTGA

Upstream 100 bases:

>100_bases
ATGGCGGCTTTATTTGTGACATCATCTGCAACCGGGAAGTCGACAACAAATTCGGCCACTCGACCGACGAACTTGTCAAG
GAATTCCAGCAGGGAGAAGA

Downstream 100 bases:

>100_bases
ACCTCGAAACGGAAAACAGGTTGTCATGGATCAAGAGGAAATAATGGAGAGAAACGGCGCTTCTGAAAATATGCACAAAA
AGGCCGGGGAGGCTGGAATT

Product: enoyl-CoA hydratase/isomerase

Products: NA

Alternate protein names: Crotonase [H]

Number of amino acids: Translated: 272; Mature: 271

Protein sequence:

>272_residues
MTMAMPQLTDATLELSERVALLTFCRNDVRNALTGTTLVDDILATLDWANRTPEVSVLVMTGEGAAFSSGGNVKEMRDRQ
GIFSGSSMTIQDQYRRGIQRIPLAMERAEIPLIASVNGPAIGAGFDLACMCDIRIGSSEAVVGETFINLGIIPGDGGAWF
LQRLVGYQRAAELTFTGRLVDATEALKLGIFLEVTEPTQLIPRSHELASRIASKSPHAVRMTKRLMKHAQRGDLADFLDL
CACFQGMAHHTDDHREAINAFLEKRAPVYAGR

Sequences:

>Translated_272_residues
MTMAMPQLTDATLELSERVALLTFCRNDVRNALTGTTLVDDILATLDWANRTPEVSVLVMTGEGAAFSSGGNVKEMRDRQ
GIFSGSSMTIQDQYRRGIQRIPLAMERAEIPLIASVNGPAIGAGFDLACMCDIRIGSSEAVVGETFINLGIIPGDGGAWF
LQRLVGYQRAAELTFTGRLVDATEALKLGIFLEVTEPTQLIPRSHELASRIASKSPHAVRMTKRLMKHAQRGDLADFLDL
CACFQGMAHHTDDHREAINAFLEKRAPVYAGR
>Mature_271_residues
TMAMPQLTDATLELSERVALLTFCRNDVRNALTGTTLVDDILATLDWANRTPEVSVLVMTGEGAAFSSGGNVKEMRDRQG
IFSGSSMTIQDQYRRGIQRIPLAMERAEIPLIASVNGPAIGAGFDLACMCDIRIGSSEAVVGETFINLGIIPGDGGAWFL
QRLVGYQRAAELTFTGRLVDATEALKLGIFLEVTEPTQLIPRSHELASRIASKSPHAVRMTKRLMKHAQRGDLADFLDLC
ACFQGMAHHTDDHREAINAFLEKRAPVYAGR

Specific function: Could Possibly Oxidizes Fatty Acids Using Specific Components (By Similarity). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=247, Percent_Identity=31.5789473684211, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI31542718, Length=239, Percent_Identity=30.5439330543933, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI68989263, Length=202, Percent_Identity=29.7029702970297, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI4502327, Length=258, Percent_Identity=29.0697674418605, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI70995211, Length=246, Percent_Identity=27.2357723577236, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI20127408, Length=154, Percent_Identity=29.2207792207792, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI150378541, Length=252, Percent_Identity=28.1746031746032, Blast_Score=69, Evalue=5e-12,
Organism=Escherichia coli, GI1787659, Length=256, Percent_Identity=32.421875, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1788597, Length=259, Percent_Identity=30.1158301158301, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI87082183, Length=270, Percent_Identity=28.5185185185185, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1787660, Length=228, Percent_Identity=30.2631578947368, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI221142681, Length=174, Percent_Identity=30.4597701149425, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1788682, Length=114, Percent_Identity=35.9649122807018, Blast_Score=66, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25145438, Length=256, Percent_Identity=32.8125, Blast_Score=116, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17554946, Length=260, Percent_Identity=32.3076923076923, Blast_Score=114, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17540714, Length=227, Percent_Identity=29.9559471365639, Blast_Score=101, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17536985, Length=229, Percent_Identity=28.3842794759825, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17558304, Length=174, Percent_Identity=28.735632183908, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17534483, Length=224, Percent_Identity=26.7857142857143, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17560910, Length=195, Percent_Identity=25.1282051282051, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17535521, Length=257, Percent_Identity=23.3463035019455, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI25144276, Length=182, Percent_Identity=25.8241758241758, Blast_Score=64, Evalue=9e-11,
Organism=Drosophila melanogaster, GI20129971, Length=253, Percent_Identity=32.4110671936759, Blast_Score=118, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24653477, Length=253, Percent_Identity=32.4110671936759, Blast_Score=118, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24653139, Length=211, Percent_Identity=32.2274881516588, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI19920382, Length=243, Percent_Identity=27.9835390946502, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21357171, Length=205, Percent_Identity=27.8048780487805, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.55 [H]

Molecular weight: Translated: 29680; Mature: 29548

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMAMPQLTDATLELSERVALLTFCRNDVRNALTGTTLVDDILATLDWANRTPEVSVLVM
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
TGEGAAFSSGGNVKEMRDRQGIFSGSSMTIQDQYRRGIQRIPLAMERAEIPLIASVNGPA
ECCCCEECCCCCHHHHHHHCCCCCCCCEEEHHHHHHHHHHCCHHHHHCCCCEEEECCCCE
IGAGFDLACMCDIRIGSSEAVVGETFINLGIIPGDGGAWFLQRLVGYQRAAELTFTGRLV
ECCCCCEEEEEEEEECCCCCHHHHHHEEEEEEECCCHHHHHHHHHHHHHHHCEEEECEEE
DATEALKLGIFLEVTEPTQLIPRSHELASRIASKSPHAVRMTKRLMKHAQRGDLADFLDL
CHHHHHEEEEEEEECCCHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHH
CACFQGMAHHTDDHREAINAFLEKRAPVYAGR
HHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TMAMPQLTDATLELSERVALLTFCRNDVRNALTGTTLVDDILATLDWANRTPEVSVLVM
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
TGEGAAFSSGGNVKEMRDRQGIFSGSSMTIQDQYRRGIQRIPLAMERAEIPLIASVNGPA
ECCCCEECCCCCHHHHHHHCCCCCCCCEEEHHHHHHHHHHCCHHHHHCCCCEEEECCCCE
IGAGFDLACMCDIRIGSSEAVVGETFINLGIIPGDGGAWFLQRLVGYQRAAELTFTGRLV
ECCCCCEEEEEEEEECCCCCHHHHHHEEEEEEECCCHHHHHHHHHHHHHHHCEEEECEEE
DATEALKLGIFLEVTEPTQLIPRSHELASRIASKSPHAVRMTKRLMKHAQRGDLADFLDL
CHHHHHEEEEEEEECCCHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHH
CACFQGMAHHTDDHREAINAFLEKRAPVYAGR
HHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]