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The map label for this gene is dksA [H]

Identifier: 78224469

GI number: 78224469

Start: 3687740

End: 3688096

Strand: Direct

Name: dksA [H]

Synonym: Gmet_3278

Alternate gene names: 78224469

Gene position: 3687740-3688096 (Clockwise)

Preceding gene: 78224468

Following gene: 78224470

Centisome position: 92.25

GC content: 58.82

Gene sequence:

>357_bases
ATGGACAAGGAGAAGCTCGAATATTTCAGATCGATCCTCAACGATGAGATCCGATCGCTCCAGGAAGAGGCGGGAAAAAC
CGTCTCGGAAATGACCGTCGACTCCACCAGCTTCCCCGACCCCACCGACCGGGCAACCCAGGAGTCAGACCGCAACTTCG
AGCTCCGCATCAGGGATCGGGAGCGCAAGCTCATCAACAAGATCCGGGAGGCCCTCGAACGGATCGAGGACGGCAGCTTC
GGCACCTGCGAGGTCTGTGGAGAGGATATCAGCGAGGCGCGCCTCAAGGCCCGTCCGGTCACCACCCTCTGCATTGACTG
CAAAATGGAGCAGGAGCGGAAAGAAAAACACCCGTAA

Upstream 100 bases:

>100_bases
CCTCTCCCCATTACCGGCGTCACATACTTTTTACTTTACTTGACCGCACAATCCCTTTATTATCTGTACGATTAAGCGTC
ATAAAGGGGAGACACGCGGC

Downstream 100 bases:

>100_bases
TCTTATCCTTTCGTCCCGCTTACTCCCCGTAGCATCTACCCGTGCCCCGGAGTCCGGATGGCTGCTCAGAATCAATTCAA
GATAGCCAGCAATGCGATTC

Product: TraR/DksA family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 118; Mature: 118

Protein sequence:

>118_residues
MDKEKLEYFRSILNDEIRSLQEEAGKTVSEMTVDSTSFPDPTDRATQESDRNFELRIRDRERKLINKIREALERIEDGSF
GTCEVCGEDISEARLKARPVTTLCIDCKMEQERKEKHP

Sequences:

>Translated_118_residues
MDKEKLEYFRSILNDEIRSLQEEAGKTVSEMTVDSTSFPDPTDRATQESDRNFELRIRDRERKLINKIREALERIEDGSF
GTCEVCGEDISEARLKARPVTTLCIDCKMEQERKEKHP
>Mature_118_residues
MDKEKLEYFRSILNDEIRSLQEEAGKTVSEMTVDSTSFPDPTDRATQESDRNFELRIRDRERKLINKIREALERIEDGSF
GTCEVCGEDISEARLKARPVTTLCIDCKMEQERKEKHP

Specific function: Dosage-Dependent Suppressor Of A Dnak Deletion Mutation. It Suppressed Not Only The Temperature-Sensitive Growth But Also The Filamentous Phenotype Of The Dnak Deletion Strain, While The Defect Of Lambda Growth Is Not Suppressed. [C]

COG id: COG1734

COG function: function code T; DnaK suppressor protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 dksA C4-type zinc finger [H]

Homologues:

Organism=Escherichia coli, GI1786338, Length=117, Percent_Identity=48.7179487179487, Blast_Score=112, Evalue=9e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012784
- InterPro:   IPR000962
- InterPro:   IPR020458 [H]

Pfam domain/function: PF01258 zf-dskA_traR [H]

EC number: NA

Molecular weight: Translated: 13784; Mature: 13784

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS01102 ZF_DKSA_1 ; PS51128 ZF_DKSA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKEKLEYFRSILNDEIRSLQEEAGKTVSEMTVDSTSFPDPTDRATQESDRNFELRIRDR
CCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECHH
ERKLINKIREALERIEDGSFGTCEVCGEDISEARLKARPVTTLCIDCKMEQERKEKHP
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHEEEECCCHHHHHCCCC
>Mature Secondary Structure
MDKEKLEYFRSILNDEIRSLQEEAGKTVSEMTVDSTSFPDPTDRATQESDRNFELRIRDR
CCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECHH
ERKLINKIREALERIEDGSFGTCEVCGEDISEARLKARPVTTLCIDCKMEQERKEKHP
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHEEEECCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 8063112 [H]