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The map label for this gene is gltD [H]

Identifier: 78224216

GI number: 78224216

Start: 3406855

End: 3408873

Strand: Reverse

Name: gltD [H]

Synonym: Gmet_3023

Alternate gene names: 78224216

Gene position: 3408873-3406855 (Counterclockwise)

Preceding gene: 78224220

Following gene: 78224215

Centisome position: 85.28

GC content: 60.13

Gene sequence:

>2019_bases
GTGGCACAGGTGGTTTTTTCGAGCTGGGGAGGGACTGTCGTCGATAATCGCGCGGGTAGCGAGGCGAAGGACGCAAGCTT
CAGGCTCCCGACTACCCTGGACGGTGACCGGGCGTTGGCCGCCTTTATGGGGTGGGACGGCATCATTGTTTTCGATAAGG
GTGTCGATGTGCCGGCCATGGCCGCGGAATACATGAAGAGGGTGCAGACCCTGTACTGTTGCGGTAAGTGCACTCCGGGC
AAGAAGGGGACCCGTGTCCTTATGGACGCATTGGCCGCCATCGTCGAGGGGAGAGGGACTGAAGCCCAGCTGGATACTAT
TGCCGATCTGGGTGATCTCCTGGCAAACTGCAAGTGTACCCTCTGCCAATCGTCCACGGTGCCGGTCATTGATGCGGTAA
AGCATTTCCGCGATGACTTCCTTGCCTACGTCAATGGCGCCAAAAAGCCCACGGCAAGCCATCGCTATATCGAGAAGTAC
ACCGCCCCGTGCATGGACCGCTGTCCCGCCCATATCGACATCCCTGCGTACATCGAGGCCATCAAGGAATACCGCTTCGA
CGAATCGCTTCACGTCATCCGCGATAATATGCCTCTTCCCTCTGTCTGTGGACGGGTTTGCCCCCATCCGTGCGAAACCC
ACTGTCGTCGCAAAAACGTGGATGATTCGATCAATATCATGGTACTCAAGCGCTCTGCGTCCGACTATGAGTGGATGCAT
AATGTTGCGCCTCCCATGAAGCCGAAGCCCCGCAAGAATAAGACGGTTGCCATTGTCGGGGCCGGGCCTGCCGGCCTTGC
CTGTGCCTATTACCTGGCCCTGGAAGGATATCCCTGCACCATCTACGAAGCTCTTCCCGAAGGGTATGGCGGCGGCATGA
TCGCCGTGGGTATCCCCCCCTACCGGCAACCGCGGCATCTGCTGCAGCGGGACATCGATATTATCGCCTCCATGGGAGTT
GAGATCATCTACAACACCCGCATCGGCGTTGATATCTCCCTCGAAGAACTCAAGAGCAAGTACAATGCTGTCTTTCTCGC
TCCCGGCGCCCACCGCTCGAAGCCCATGGGGGTCGAGGGTGAGGACAAGGGGTACAAGGGGTTCCTCAGGGGAGGGATCG
ATTTCCTCCGTGAGGCCTATATGGGGCGCCCTACCGGCATGGGTAAGAAAGTGGTTGTCGTGGGCGGCGGTAACACTGCC
ATCGACTGCGTCCGTGTTGCTCTGCGTGAAGGGGCCGAGGAGTCGATCCTCCTTTATCGCCGCTCCAGGAAGGAGATGCC
GGCCGACGTGTGGGAGGTGGATGGCGCCGACGAGGAGGGGGTACGCTTCGAGTTTCAGGTGCTTCCCACCAAAATCATCG
TCGACCAGAACGAACAGGTTACTGGCGTCGAGTGTGTCCGGATGGCCCTCGGAGAGCCCGACGCCTCAGGGCGCCGTCGT
CCCGAACCGGTTCCCGGCAGCGAGTTCGTGGTTGAGTGCGATACGGTCATCCCGGCCATCGGTCAGGACCCGGACCTCTC
GTTCATTCCCGAGAACATGGGGATCGACATCACCAAATGGAATACCGTGGTCACCAAGTACATTCCCCTCAAGGACGCAG
CGGGCAAGGATCTGAAGGATGGTATGGGGAACCCCCTCGTCCGGACCCTCATTACCGACCTGGACGGCGTCTTTGCCGGT
GGTGACGCCGAGATCGGTCCGCTGACCGTCGTTGCCTGCATCGGCAATGCCCACCGGGCGGCACGGGTCATCCAGCGCTG
GCTGGAGGAGGGAAAGGTGTACCTGACCGACGACGAGTTCATGGAGGACATCCTTACCAACCTGCCGGTCTACGACAAGG
GTGAAGCGGTGCCGTGGCTCGACTCGGTTGAGAGGGCGCACCAGGCCGAAGTTCATGGCCGGGAGCGGGCCAGCAAGGGG
AACTACCAGGAAGTCGAGCTCGGTTTTGCCGACAGTCAGGCGATCCGCGAAGCAGAGCGTTGTCTGCGTTGCTACCGCGT
CGCTATGGCTGCGGTCTAA

Upstream 100 bases:

>100_bases
ATTGCATACTGTATACAATTGTGGCTAGCTAAAACAATTAATAAATATAAGTGGTTAAGTGATATAGATCCTGTCTGTGA
AGGTCTGAACGGAGGCGTGC

Downstream 100 bases:

>100_bases
TCCACACAAGTCAGCATGTCACTTCGGCCCAAGGCCGGGGCCATGGCGGCCCGGGAGTCGGTGACGACCCCGGGCGCTGG
TGTGTCCCGGGTCTGGGCCG

Product: FAD-dependent pyridine nucleotide-disulphide oxidoreductase

Products: NA

Alternate protein names: Glutamate synthase subunit beta; GLTS beta chain; NADPH-GOGAT [H]

Number of amino acids: Translated: 672; Mature: 671

Protein sequence:

>672_residues
MAQVVFSSWGGTVVDNRAGSEAKDASFRLPTTLDGDRALAAFMGWDGIIVFDKGVDVPAMAAEYMKRVQTLYCCGKCTPG
KKGTRVLMDALAAIVEGRGTEAQLDTIADLGDLLANCKCTLCQSSTVPVIDAVKHFRDDFLAYVNGAKKPTASHRYIEKY
TAPCMDRCPAHIDIPAYIEAIKEYRFDESLHVIRDNMPLPSVCGRVCPHPCETHCRRKNVDDSINIMVLKRSASDYEWMH
NVAPPMKPKPRKNKTVAIVGAGPAGLACAYYLALEGYPCTIYEALPEGYGGGMIAVGIPPYRQPRHLLQRDIDIIASMGV
EIIYNTRIGVDISLEELKSKYNAVFLAPGAHRSKPMGVEGEDKGYKGFLRGGIDFLREAYMGRPTGMGKKVVVVGGGNTA
IDCVRVALREGAEESILLYRRSRKEMPADVWEVDGADEEGVRFEFQVLPTKIIVDQNEQVTGVECVRMALGEPDASGRRR
PEPVPGSEFVVECDTVIPAIGQDPDLSFIPENMGIDITKWNTVVTKYIPLKDAAGKDLKDGMGNPLVRTLITDLDGVFAG
GDAEIGPLTVVACIGNAHRAARVIQRWLEEGKVYLTDDEFMEDILTNLPVYDKGEAVPWLDSVERAHQAEVHGRERASKG
NYQEVELGFADSQAIREAERCLRCYRVAMAAV

Sequences:

>Translated_672_residues
MAQVVFSSWGGTVVDNRAGSEAKDASFRLPTTLDGDRALAAFMGWDGIIVFDKGVDVPAMAAEYMKRVQTLYCCGKCTPG
KKGTRVLMDALAAIVEGRGTEAQLDTIADLGDLLANCKCTLCQSSTVPVIDAVKHFRDDFLAYVNGAKKPTASHRYIEKY
TAPCMDRCPAHIDIPAYIEAIKEYRFDESLHVIRDNMPLPSVCGRVCPHPCETHCRRKNVDDSINIMVLKRSASDYEWMH
NVAPPMKPKPRKNKTVAIVGAGPAGLACAYYLALEGYPCTIYEALPEGYGGGMIAVGIPPYRQPRHLLQRDIDIIASMGV
EIIYNTRIGVDISLEELKSKYNAVFLAPGAHRSKPMGVEGEDKGYKGFLRGGIDFLREAYMGRPTGMGKKVVVVGGGNTA
IDCVRVALREGAEESILLYRRSRKEMPADVWEVDGADEEGVRFEFQVLPTKIIVDQNEQVTGVECVRMALGEPDASGRRR
PEPVPGSEFVVECDTVIPAIGQDPDLSFIPENMGIDITKWNTVVTKYIPLKDAAGKDLKDGMGNPLVRTLITDLDGVFAG
GDAEIGPLTVVACIGNAHRAARVIQRWLEEGKVYLTDDEFMEDILTNLPVYDKGEAVPWLDSVERAHQAEVHGRERASKG
NYQEVELGFADSQAIREAERCLRCYRVAMAAV
>Mature_671_residues
AQVVFSSWGGTVVDNRAGSEAKDASFRLPTTLDGDRALAAFMGWDGIIVFDKGVDVPAMAAEYMKRVQTLYCCGKCTPGK
KGTRVLMDALAAIVEGRGTEAQLDTIADLGDLLANCKCTLCQSSTVPVIDAVKHFRDDFLAYVNGAKKPTASHRYIEKYT
APCMDRCPAHIDIPAYIEAIKEYRFDESLHVIRDNMPLPSVCGRVCPHPCETHCRRKNVDDSINIMVLKRSASDYEWMHN
VAPPMKPKPRKNKTVAIVGAGPAGLACAYYLALEGYPCTIYEALPEGYGGGMIAVGIPPYRQPRHLLQRDIDIIASMGVE
IIYNTRIGVDISLEELKSKYNAVFLAPGAHRSKPMGVEGEDKGYKGFLRGGIDFLREAYMGRPTGMGKKVVVVGGGNTAI
DCVRVALREGAEESILLYRRSRKEMPADVWEVDGADEEGVRFEFQVLPTKIIVDQNEQVTGVECVRMALGEPDASGRRRP
EPVPGSEFVVECDTVIPAIGQDPDLSFIPENMGIDITKWNTVVTKYIPLKDAAGKDLKDGMGNPLVRTLITDLDGVFAGG
DAEIGPLTVVACIGNAHRAARVIQRWLEEGKVYLTDDEFMEDILTNLPVYDKGEAVPWLDSVERAHQAEVHGRERASKGN
YQEVELGFADSQAIREAERCLRCYRVAMAAV

Specific function: NITROGEN METABOLISM, GLUTAMATE BIOSYNTHESIS. THE CATALYZED REACTION BRINGS TOGETHER THE NITROGEN AND CARBON METABOLISM. [C]

COG id: COG0493

COG function: function code ER; NADPH-dependent glutamate synthase beta chain and related oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI119943098, Length=462, Percent_Identity=27.0562770562771, Blast_Score=125, Evalue=9e-29,
Organism=Escherichia coli, GI1789606, Length=440, Percent_Identity=37.2727272727273, Blast_Score=246, Evalue=3e-66,
Organism=Escherichia coli, GI1788811, Length=437, Percent_Identity=36.3844393592677, Blast_Score=245, Evalue=5e-66,
Organism=Escherichia coli, GI87082180, Length=437, Percent_Identity=34.5537757437071, Blast_Score=229, Evalue=4e-61,
Organism=Escherichia coli, GI1789243, Length=432, Percent_Identity=36.1111111111111, Blast_Score=213, Evalue=3e-56,
Organism=Escherichia coli, GI1788468, Length=441, Percent_Identity=28.5714285714286, Blast_Score=148, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17570289, Length=472, Percent_Identity=25.2118644067797, Blast_Score=122, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI71984108, Length=462, Percent_Identity=27.9220779220779, Blast_Score=111, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17543860, Length=170, Percent_Identity=31.1764705882353, Blast_Score=72, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320030, Length=500, Percent_Identity=27.6, Blast_Score=162, Evalue=2e-40,
Organism=Drosophila melanogaster, GI28574881, Length=446, Percent_Identity=27.1300448430493, Blast_Score=146, Evalue=4e-35,
Organism=Drosophila melanogaster, GI24665539, Length=446, Percent_Identity=27.1300448430493, Blast_Score=146, Evalue=4e-35,
Organism=Drosophila melanogaster, GI24665547, Length=446, Percent_Identity=27.1300448430493, Blast_Score=146, Evalue=4e-35,
Organism=Drosophila melanogaster, GI24665543, Length=446, Percent_Identity=27.1300448430493, Blast_Score=146, Evalue=4e-35,
Organism=Drosophila melanogaster, GI24640763, Length=341, Percent_Identity=31.6715542521994, Blast_Score=121, Evalue=2e-27,
Organism=Drosophila melanogaster, GI18858217, Length=341, Percent_Identity=31.6715542521994, Blast_Score=121, Evalue=2e-27,

Paralogues:

None

Copy number: 620 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 180 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR013027
- InterPro:   IPR012285
- InterPro:   IPR006006
- InterPro:   IPR009051
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.4.1.13 [H]

Molecular weight: Translated: 73748; Mature: 73617

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQVVFSSWGGTVVDNRAGSEAKDASFRLPTTLDGDRALAAFMGWDGIIVFDKGVDVPAM
CCEEEEECCCCEEEECCCCCCCCCCCEECCCCCCCCHHHHHHCCCCEEEEEECCCCCHHH
AAEYMKRVQTLYCCGKCTPGKKGTRVLMDALAAIVEGRGTEAQLDTIADLGDLLANCKCT
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCEEE
LCQSSTVPVIDAVKHFRDDFLAYVNGAKKPTASHRYIEKYTAPCMDRCPAHIDIPAYIEA
EECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHCCCCCCHHHHHHH
IKEYRFDESLHVIRDNMPLPSVCGRVCPHPCETHCRRKNVDDSINIMVLKRSASDYEWMH
HHHHCCCCCHHHHCCCCCCHHHHHHHCCCCHHHHHHHCCCCCCEEEEEEECCCCCHHHHH
NVAPPMKPKPRKNKTVAIVGAGPAGLACAYYLALEGYPCTIYEALPEGYGGGMIAVGIPP
HCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCEEHHHHCCCCCCCCEEEECCCC
YRQPRHLLQRDIDIIASMGVEIIYNTRIGVDISLEELKSKYNAVFLAPGAHRSKPMGVEG
CCCHHHHHHHHHHHHHHCCEEEEEECCCCCEEEHHHHHHHCCEEEECCCCCCCCCCCCCC
EDKGYKGFLRGGIDFLREAYMGRPTGMGKKVVVVGGGNTAIDCVRVALREGAEESILLYR
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCHHHHHHH
RSRKEMPADVWEVDGADEEGVRFEFQVLPTKIIVDQNEQVTGVECVRMALGEPDASGRRR
HHHHCCCCCCEECCCCCCCCCEEEEEEECEEEEECCCCCCHHHHHHHHHHCCCCCCCCCC
PEPVPGSEFVVECDTVIPAIGQDPDLSFIPENMGIDITKWNTVVTKYIPLKDAAGKDLKD
CCCCCCCCEEEEECHHCCCCCCCCCCCCCCCCCCEEEEECCEEEEEEECCCCCCCCCHHH
GMGNPLVRTLITDLDGVFAGGDAEIGPLTVVACIGNAHRAARVIQRWLEEGKVYLTDDEF
CCCCHHHHHHHHHHCCEEECCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCEEEECHHH
MEDILTNLPVYDKGEAVPWLDSVERAHQAEVHGRERASKGNYQEVELGFADSQAIREAER
HHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHH
CLRCYRVAMAAV
HHHHHHHHHHCC
>Mature Secondary Structure 
AQVVFSSWGGTVVDNRAGSEAKDASFRLPTTLDGDRALAAFMGWDGIIVFDKGVDVPAM
CEEEEECCCCEEEECCCCCCCCCCCEECCCCCCCCHHHHHHCCCCEEEEEECCCCCHHH
AAEYMKRVQTLYCCGKCTPGKKGTRVLMDALAAIVEGRGTEAQLDTIADLGDLLANCKCT
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCEEE
LCQSSTVPVIDAVKHFRDDFLAYVNGAKKPTASHRYIEKYTAPCMDRCPAHIDIPAYIEA
EECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHCCCCCCHHHHHHH
IKEYRFDESLHVIRDNMPLPSVCGRVCPHPCETHCRRKNVDDSINIMVLKRSASDYEWMH
HHHHCCCCCHHHHCCCCCCHHHHHHHCCCCHHHHHHHCCCCCCEEEEEEECCCCCHHHHH
NVAPPMKPKPRKNKTVAIVGAGPAGLACAYYLALEGYPCTIYEALPEGYGGGMIAVGIPP
HCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCEEHHHHCCCCCCCCEEEECCCC
YRQPRHLLQRDIDIIASMGVEIIYNTRIGVDISLEELKSKYNAVFLAPGAHRSKPMGVEG
CCCHHHHHHHHHHHHHHCCEEEEEECCCCCEEEHHHHHHHCCEEEECCCCCCCCCCCCCC
EDKGYKGFLRGGIDFLREAYMGRPTGMGKKVVVVGGGNTAIDCVRVALREGAEESILLYR
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCHHHHHHH
RSRKEMPADVWEVDGADEEGVRFEFQVLPTKIIVDQNEQVTGVECVRMALGEPDASGRRR
HHHHCCCCCCEECCCCCCCCCEEEEEEECEEEEECCCCCCHHHHHHHHHHCCCCCCCCCC
PEPVPGSEFVVECDTVIPAIGQDPDLSFIPENMGIDITKWNTVVTKYIPLKDAAGKDLKD
CCCCCCCCEEEEECHHCCCCCCCCCCCCCCCCCCEEEEECCEEEEEEECCCCCCCCCHHH
GMGNPLVRTLITDLDGVFAGGDAEIGPLTVVACIGNAHRAARVIQRWLEEGKVYLTDDEF
CCCCHHHHHHHHHHCCEEECCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCEEEECHHH
MEDILTNLPVYDKGEAVPWLDSVERAHQAEVHGRERASKGNYQEVELGFADSQAIREAER
HHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHH
CLRCYRVAMAAV
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3326786; 9278503; 9298646; 9600841; 2643092 [H]