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The map label for this gene is nuoG2 [H]

Identifier: 78224215

GI number: 78224215

Start: 3404238

End: 3406733

Strand: Reverse

Name: nuoG2 [H]

Synonym: Gmet_3022

Alternate gene names: 78224215

Gene position: 3406733-3404238 (Counterclockwise)

Preceding gene: 78224216

Following gene: 78224205

Centisome position: 85.22

GC content: 62.3

Gene sequence:

>2496_bases
ATGGTCAGTCTTACAATCGACGGGAAGGACATCTCGGTAGCCAAGGGGAGCACCATCCTTGACGCGGCGGCGCAGCTTGG
CATCACGATACCGACTCTCTGCTGGCTCAAGAAGGTATCGCCAACAGGCGCGTGCCGCGTCTGCGCGGTGGAGGTGGAGG
GTGTCGACCGCCCCATGACCGCCTGCAACACGCCGGTCAAGGAGGGAATCAAGGTAACGACCCAGTCGGAGAAGCTCTCC
CGGATCCGTCAGAAGATCATGGAGCTGATGCTGGTCAACCACCCCCTCGACTGCCCCGTCTGCGACGCCGGCGGCGAGTG
TGATCTTCAGAACTCCTGCTACGGTCTGGGGGCATCACGCCAGGAATACTCGGCGCTCCTGGAACGGCGGGAGATCCGCT
ACAACTGGCCCCTCATCGAGAGCGATCCGAACCGCTGCATTCTCTGCGAGAAGTGCGTCAAGGTCGACCACGAGGTCGTG
GGATGCGATGCCATTGCCGTGGTGAACCGGGGCGAGGCGACGATCATCGATACCATTGACGGCAAGCCCCTCAACTGCGA
ATTCTGCGGCAACTGTGTCGGTGCCTGCCCCACCGGTACCCTCATCAGCAAGCCTTTTAAATTCCGTGGCCGTCCCTGGG
CCTTTACCGTAACCAAGAGCGTCTGTGCCTTTTGCTCCACCGGATGCCAGATCGAGTATCACACCCGCAACGGCCGCGTC
GAAAGGGTCACGAGCGACGACGATAACTTCAACAGCGGCAATCTCTGCATCAACGGCCGTTTCGGGTACAGCTACATCAA
TTCCTCCGACCGCCTGACACAGCCCCTGGTGCGGGGCGAGAAGGTGGACTGGAACGCCGCCATGGGGACTGCCGCGACGG
GGCTCAAGGAGATCGTCGCCAATTATGGTCCTGACGCAGTGGCTGGTTTCGGTTCGCCGCGGGTCACCAACGAGGAGAGC
TACCTCTTCCAGAAACTCTTCCGGAACGCCTTGGGGAGTGGCAACATCGATTCCGAGGCGCGGCTTGGCTTTGCCCAGGC
CCAGAAGGCGCTCCGTGAGCGGTTGGGCCTTCGGGGCGCCAGCGCCACCATCGACGCCATTGACAGGGCCGGTGCAATTC
TTGTCTTCGGTTGCGATCTGAACGCCGAGGCAACCGGCATAGAGTATCGGGTAATCAAGGCTGCCACCAAGAACGACGCA
AAGCTGGTCCTCGCGAACATGCGGGACGTGAAACTGAAGAAGTTTGCCAACAGCCACCTCAAGTACCGGCCGGGGAGCGA
GCTGGCCCTCATCAATGCCCTCACACGGGTCGTGCTCGACGAAGGTCTGCAGGACAACGATTTTGCCTCAGCCCGCATTG
CCAACCTGGCCGAACTGACTGCAGCCCTCGGCACCGTATCGGTTGCCGATGCCGCAGCTGCCGTCGGTCTGTCCGAGGCC
GAGCTTCGCGCTGCCGCCCGGCTGCTCGGCAAGAAAAAGAGCGTGGCCGTTCTCTTCGGCGCCGATCTTATGCGGAGTAG
CGGAGCCGATGAAGCCGTGAATGCTCTCGCGAATCTTGCCATCGTCCTGGGTGCCCTCGGCAAGGAAACGGGGGGCCTTT
TCCCTGTCTATGAAAAGACCAATATCCGCGGTCTCCTCGACATGGGCGTTGCACCTGACATGCTTCCGGGGTACGCGGCA
CCGGCGGTTGCGGGCAAGGATCTCTGGCAGATCGTCGAGGGGATCGAGCAGGGAAGCGTCAAGGCCCTCTATCTCCTCGG
GTGTGATCCCGTCGCCTCCTTCCCCGAGGGCGAGAGGATTCGGGCAGCCCTCGGCAAGCTGGAGCTTCTCATCGTCCAGG
ACCCGTTCCCCGGCGAGTCGGCGAAGCAGGCCCATATTGTCCTCCCCTCTTCGGTGGCGGCAGAAAAGAGCGGAACCTTC
ACCACCATTGACGGCCGAGTCCAGTCCATTGCCAAGGCAGCCAACCCTCCTGGCGAGGCCCGCGAGGACTGGGACATTCT
GACCGAACTCTGTAACCGGCTGACGGGTGAGAGCCGTCCGGCGTCCCCGGCATCGATCATGGCCGAGATTACGGCACTCG
TTCCAGGGTACGGGGCCGATGTGGTACTGCCGGCGGGCTTCCCTTCCGCTGGGCCGGTTTCCCTCGCCGTTTCGAAGGAT
GTACGTCCGGTTCAGTCTCAGCAGGCCCCTCTGCTTCTTGCTGGCGCTATCCTTTACCATAGCGGCACCACCACCACCTG
GTCGAAGAACAACCTTGAGATTGTGCCGGCCGGCTACGTGGAGATCCACCCCGACGACGCCGCCAGGCTGGGCGTGTCGG
ACGGTTCCTCGCTTCGTATCTCTGCGGGTGCTGTGAGTGTAAACGCCCCCGCGCGGGTTTCGGGTAAGGTACAGGCTGGT
CTCCTCTTCGCGCCTTCCCATTTCCGCGCCATGAACGTCAATGCCCTCCTCGGGAAAGGGGCCGGTGTGGTGCCGGTAAA
GGTGGAAAAGGCGTAA

Upstream 100 bases:

>100_bases
CTTCGGCCCAAGGCCGGGGCCATGGCGGCCCGGGAGTCGGTGACGACCCCGGGCGCTGGTGTGTCCCGGGTCTGGGCCGC
TTTCCAGGGGTGAAACGGAT

Downstream 100 bases:

>100_bases
CCGGCCTTTTGCCCGAGAAAAAAGCACGAAACCCCGCCGTACGAAACGGCGGGGTTTTTTGTTTTTGGAGGCGCGCGAAC
ACTATTGCTGACAGGCCGGT

Product: Fe(III) reductase subunit alpha

Products: NA

Alternate protein names: NADH dehydrogenase I subunit G 2; NDH-1 subunit G 2 [H]

Number of amino acids: Translated: 831; Mature: 831

Protein sequence:

>831_residues
MVSLTIDGKDISVAKGSTILDAAAQLGITIPTLCWLKKVSPTGACRVCAVEVEGVDRPMTACNTPVKEGIKVTTQSEKLS
RIRQKIMELMLVNHPLDCPVCDAGGECDLQNSCYGLGASRQEYSALLERREIRYNWPLIESDPNRCILCEKCVKVDHEVV
GCDAIAVVNRGEATIIDTIDGKPLNCEFCGNCVGACPTGTLISKPFKFRGRPWAFTVTKSVCAFCSTGCQIEYHTRNGRV
ERVTSDDDNFNSGNLCINGRFGYSYINSSDRLTQPLVRGEKVDWNAAMGTAATGLKEIVANYGPDAVAGFGSPRVTNEES
YLFQKLFRNALGSGNIDSEARLGFAQAQKALRERLGLRGASATIDAIDRAGAILVFGCDLNAEATGIEYRVIKAATKNDA
KLVLANMRDVKLKKFANSHLKYRPGSELALINALTRVVLDEGLQDNDFASARIANLAELTAALGTVSVADAAAAVGLSEA
ELRAAARLLGKKKSVAVLFGADLMRSSGADEAVNALANLAIVLGALGKETGGLFPVYEKTNIRGLLDMGVAPDMLPGYAA
PAVAGKDLWQIVEGIEQGSVKALYLLGCDPVASFPEGERIRAALGKLELLIVQDPFPGESAKQAHIVLPSSVAAEKSGTF
TTIDGRVQSIAKAANPPGEAREDWDILTELCNRLTGESRPASPASIMAEITALVPGYGADVVLPAGFPSAGPVSLAVSKD
VRPVQSQQAPLLLAGAILYHSGTTTTWSKNNLEIVPAGYVEIHPDDAARLGVSDGSSLRISAGAVSVNAPARVSGKVQAG
LLFAPSHFRAMNVNALLGKGAGVVPVKVEKA

Sequences:

>Translated_831_residues
MVSLTIDGKDISVAKGSTILDAAAQLGITIPTLCWLKKVSPTGACRVCAVEVEGVDRPMTACNTPVKEGIKVTTQSEKLS
RIRQKIMELMLVNHPLDCPVCDAGGECDLQNSCYGLGASRQEYSALLERREIRYNWPLIESDPNRCILCEKCVKVDHEVV
GCDAIAVVNRGEATIIDTIDGKPLNCEFCGNCVGACPTGTLISKPFKFRGRPWAFTVTKSVCAFCSTGCQIEYHTRNGRV
ERVTSDDDNFNSGNLCINGRFGYSYINSSDRLTQPLVRGEKVDWNAAMGTAATGLKEIVANYGPDAVAGFGSPRVTNEES
YLFQKLFRNALGSGNIDSEARLGFAQAQKALRERLGLRGASATIDAIDRAGAILVFGCDLNAEATGIEYRVIKAATKNDA
KLVLANMRDVKLKKFANSHLKYRPGSELALINALTRVVLDEGLQDNDFASARIANLAELTAALGTVSVADAAAAVGLSEA
ELRAAARLLGKKKSVAVLFGADLMRSSGADEAVNALANLAIVLGALGKETGGLFPVYEKTNIRGLLDMGVAPDMLPGYAA
PAVAGKDLWQIVEGIEQGSVKALYLLGCDPVASFPEGERIRAALGKLELLIVQDPFPGESAKQAHIVLPSSVAAEKSGTF
TTIDGRVQSIAKAANPPGEAREDWDILTELCNRLTGESRPASPASIMAEITALVPGYGADVVLPAGFPSAGPVSLAVSKD
VRPVQSQQAPLLLAGAILYHSGTTTTWSKNNLEIVPAGYVEIHPDDAARLGVSDGSSLRISAGAVSVNAPARVSGKVQAG
LLFAPSHFRAMNVNALLGKGAGVVPVKVEKA
>Mature_831_residues
MVSLTIDGKDISVAKGSTILDAAAQLGITIPTLCWLKKVSPTGACRVCAVEVEGVDRPMTACNTPVKEGIKVTTQSEKLS
RIRQKIMELMLVNHPLDCPVCDAGGECDLQNSCYGLGASRQEYSALLERREIRYNWPLIESDPNRCILCEKCVKVDHEVV
GCDAIAVVNRGEATIIDTIDGKPLNCEFCGNCVGACPTGTLISKPFKFRGRPWAFTVTKSVCAFCSTGCQIEYHTRNGRV
ERVTSDDDNFNSGNLCINGRFGYSYINSSDRLTQPLVRGEKVDWNAAMGTAATGLKEIVANYGPDAVAGFGSPRVTNEES
YLFQKLFRNALGSGNIDSEARLGFAQAQKALRERLGLRGASATIDAIDRAGAILVFGCDLNAEATGIEYRVIKAATKNDA
KLVLANMRDVKLKKFANSHLKYRPGSELALINALTRVVLDEGLQDNDFASARIANLAELTAALGTVSVADAAAAVGLSEA
ELRAAARLLGKKKSVAVLFGADLMRSSGADEAVNALANLAIVLGALGKETGGLFPVYEKTNIRGLLDMGVAPDMLPGYAA
PAVAGKDLWQIVEGIEQGSVKALYLLGCDPVASFPEGERIRAALGKLELLIVQDPFPGESAKQAHIVLPSSVAAEKSGTF
TTIDGRVQSIAKAANPPGEAREDWDILTELCNRLTGESRPASPASIMAEITALVPGYGADVVLPAGFPSAGPVSLAVSKD
VRPVQSQQAPLLLAGAILYHSGTTTTWSKNNLEIVPAGYVEIHPDDAARLGVSDGSSLRISAGAVSVNAPARVSGKVQAG
LLFAPSHFRAMNVNALLGKGAGVVPVKVEKA

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG3383

COG function: function code R; Uncharacterized anaerobic dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Homo sapiens, GI33519475, Length=410, Percent_Identity=31.9512195121951, Blast_Score=221, Evalue=3e-57,
Organism=Escherichia coli, GI3868721, Length=661, Percent_Identity=27.3827534039334, Blast_Score=271, Evalue=1e-73,
Organism=Escherichia coli, GI145693161, Length=679, Percent_Identity=28.4241531664212, Blast_Score=216, Evalue=4e-57,
Organism=Escherichia coli, GI1788534, Length=552, Percent_Identity=22.6449275362319, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1787870, Length=473, Percent_Identity=24.1014799154334, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI87081797, Length=542, Percent_Identity=21.0332103321033, Blast_Score=68, Evalue=3e-12,
Organism=Escherichia coli, GI3868720, Length=261, Percent_Identity=24.904214559387, Blast_Score=64, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17565758, Length=691, Percent_Identity=29.0882778581766, Blast_Score=251, Evalue=1e-66,
Organism=Caenorhabditis elegans, GI32566231, Length=675, Percent_Identity=28.4444444444444, Blast_Score=228, Evalue=8e-60,
Organism=Caenorhabditis elegans, GI193209088, Length=245, Percent_Identity=38.7755102040816, Blast_Score=180, Evalue=3e-45,
Organism=Drosophila melanogaster, GI24640559, Length=414, Percent_Identity=31.6425120772947, Blast_Score=208, Evalue=2e-53,
Organism=Drosophila melanogaster, GI24640557, Length=414, Percent_Identity=31.6425120772947, Blast_Score=208, Evalue=2e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR009010
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006963
- InterPro:   IPR006655
- InterPro:   IPR000283
- InterPro:   IPR019574 [H]

Pfam domain/function: PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF01568 Molydop_binding; PF10588 NADH-G_4Fe-4S_3 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 87782; Mature: 87782

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS00641 COMPLEX1_75K_1 ; PS00642 COMPLEX1_75K_2 ; PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSLTIDGKDISVAKGSTILDAAAQLGITIPTLCWLKKVSPTGACRVCAVEVEGVDRPMT
CEEEEECCCEEEEECCCHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEEEEEECCCCCCHH
ACNTPVKEGIKVTTQSEKLSRIRQKIMELMLVNHPLDCPVCDAGGECDLQNSCYGLGASR
HCCCCHHCCEEEEECHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCH
QEYSALLERREIRYNWPLIESDPNRCILCEKCVKVDHEVVGCDAIAVVNRGEATIIDTID
HHHHHHHHHHHCEECCCEEECCCCCEEEEHHHHHCCCCEECCCEEEEEECCCEEEEECCC
GKPLNCEFCGNCVGACPTGTLISKPFKFRGRPWAFTVTKSVCAFCSTGCQIEYHTRNGRV
CCCCCHHHHCCCCCCCCCCHHHCCCCCCCCCCEEEEHHHHHHHHHCCCCEEEEECCCCEE
ERVTSDDDNFNSGNLCINGRFGYSYINSSDRLTQPLVRGEKVDWNAAMGTAATGLKEIVA
EEEECCCCCCCCCCEEEECCCCCCEECCCCHHHHHHHCCCCCCCCHHCCHHHHHHHHHHH
NYGPDAVAGFGSPRVTNEESYLFQKLFRNALGSGNIDSEARLGFAQAQKALRERLGLRGA
CCCCCHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHCCHHHHHHHHHHHHCCCCC
SATIDAIDRAGAILVFGCDLNAEATGIEYRVIKAATKNDAKLVLANMRDVKLKKFANSHL
CCHHHHHHCCCEEEEEECCCCCCCCCEEEEEEEECCCCCCEEEEECCCHHHHHHHHCCCC
KYRPGSELALINALTRVVLDEGLQDNDFASARIANLAELTAALGTVSVADAAAAVGLSEA
EECCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
ELRAAARLLGKKKSVAVLFGADLMRSSGADEAVNALANLAIVLGALGKETGGLFPVYEKT
HHHHHHHHHCCCCCEEEEECHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECC
NIRGLLDMGVAPDMLPGYAAPAVAGKDLWQIVEGIEQGSVKALYLLGCDPVASFPEGERI
CCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCHHH
RAALGKLELLIVQDPFPGESAKQAHIVLPSSVAAEKSGTFTTIDGRVQSIAKAANPPGEA
HHHHCCEEEEEEECCCCCCCCCCEEEECCCHHHHCCCCCEEEECHHHHHHHHHCCCCCCC
REDWDILTELCNRLTGESRPASPASIMAEITALVPGYGADVVLPAGFPSAGPVSLAVSKD
CHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCEEEECCCCCCCCEEEEECCC
VRPVQSQQAPLLLAGAILYHSGTTTTWSKNNLEIVPAGYVEIHPDDAARLGVSDGSSLRI
CCCCCCCCCCEEEEEEEEEECCCCCEECCCCEEEEECCEEEECCCCCCEEECCCCCEEEE
SAGAVSVNAPARVSGKVQAGLLFAPSHFRAMNVNALLGKGAGVVPVKVEKA
EECEEEECCCCCCCCCEEEEEEECCCCCEEEECCEEECCCCCEEEEEEECC
>Mature Secondary Structure
MVSLTIDGKDISVAKGSTILDAAAQLGITIPTLCWLKKVSPTGACRVCAVEVEGVDRPMT
CEEEEECCCEEEEECCCHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEEEEEECCCCCCHH
ACNTPVKEGIKVTTQSEKLSRIRQKIMELMLVNHPLDCPVCDAGGECDLQNSCYGLGASR
HCCCCHHCCEEEEECHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCH
QEYSALLERREIRYNWPLIESDPNRCILCEKCVKVDHEVVGCDAIAVVNRGEATIIDTID
HHHHHHHHHHHCEECCCEEECCCCCEEEEHHHHHCCCCEECCCEEEEEECCCEEEEECCC
GKPLNCEFCGNCVGACPTGTLISKPFKFRGRPWAFTVTKSVCAFCSTGCQIEYHTRNGRV
CCCCCHHHHCCCCCCCCCCHHHCCCCCCCCCCEEEEHHHHHHHHHCCCCEEEEECCCCEE
ERVTSDDDNFNSGNLCINGRFGYSYINSSDRLTQPLVRGEKVDWNAAMGTAATGLKEIVA
EEEECCCCCCCCCCEEEECCCCCCEECCCCHHHHHHHCCCCCCCCHHCCHHHHHHHHHHH
NYGPDAVAGFGSPRVTNEESYLFQKLFRNALGSGNIDSEARLGFAQAQKALRERLGLRGA
CCCCCHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHCCHHHHHHHHHHHHCCCCC
SATIDAIDRAGAILVFGCDLNAEATGIEYRVIKAATKNDAKLVLANMRDVKLKKFANSHL
CCHHHHHHCCCEEEEEECCCCCCCCCEEEEEEEECCCCCCEEEEECCCHHHHHHHHCCCC
KYRPGSELALINALTRVVLDEGLQDNDFASARIANLAELTAALGTVSVADAAAAVGLSEA
EECCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
ELRAAARLLGKKKSVAVLFGADLMRSSGADEAVNALANLAIVLGALGKETGGLFPVYEKT
HHHHHHHHHCCCCCEEEEECHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECC
NIRGLLDMGVAPDMLPGYAAPAVAGKDLWQIVEGIEQGSVKALYLLGCDPVASFPEGERI
CCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCHHH
RAALGKLELLIVQDPFPGESAKQAHIVLPSSVAAEKSGTFTTIDGRVQSIAKAANPPGEA
HHHHCCEEEEEEECCCCCCCCCCEEEECCCHHHHCCCCCEEEECHHHHHHHHHCCCCCCC
REDWDILTELCNRLTGESRPASPASIMAEITALVPGYGADVVLPAGFPSAGPVSLAVSKD
CHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCEEEECCCCCCCCEEEEECCC
VRPVQSQQAPLLLAGAILYHSGTTTTWSKNNLEIVPAGYVEIHPDDAARLGVSDGSSLRI
CCCCCCCCCCEEEEEEEEEECCCCCEECCCCEEEEECCEEEECCCCCCEEECCCCCEEEE
SAGAVSVNAPARVSGKVQAGLLFAPSHFRAMNVNALLGKGAGVVPVKVEKA
EECEEEECCCCCCCCCEEEEEEECCCCCEEEECCEEECCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481432 [H]