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The map label for this gene is accD [H]

Identifier: 78223679

GI number: 78223679

Start: 2816816

End: 2817658

Strand: Reverse

Name: accD [H]

Synonym: Gmet_2476

Alternate gene names: 78223679

Gene position: 2817658-2816816 (Counterclockwise)

Preceding gene: 78223680

Following gene: 78223678

Centisome position: 70.49

GC content: 61.68

Gene sequence:

>843_bases
ATGGCGTGGTTCAAACGCGACAAGGCGCCGGGCGCGGCAGACAAGAAGGTGAAGGTTCCCGAGGGGCTGCTTACCAAGTG
CGTGAGCTGCAAGGCTAACCTCCTAACGAAGGATCTGGAGAAAAACATCAATGTCTGCCCCCAGTGCGGCCACCACTACC
GGATCTCGGCCCGGCAGCGGATCGATCTGCTCATGGATCCGGGGAGTTTTGCGGAGCACGACGCCGGCATGACGTCGGTG
GACGTCCTCAACTTCAAGGATTCCAAGAGCTATCAGGACCGCATCCAGCAGGCGGTTGCCAAGGGGGGCTCCCGTGACGC
CGTTGTCTGCGGCGAGGGGGCGATTGACGCTGTCCCGGTGCAGCTGGCTGTCTTCGACTTCTCCTTCATGGGGGGAAGCA
TGGGGAGCGTGGTGGGGGAGAAGATCACCCGCGCCATCGAGCGGGGGATTGAGAAGCGGACCCCGGTCATCATCATCTCC
GCCTCGGGCGGCGCTCGGATGCAGGAAAGCATTCTGTCGCTGATGCAGATGGCGAAGACCTCGGCAGCCCTGGCGAAGCT
GAAGGATCTGGGGCTTCCCTACATTTCGATCCTCACCGATCCCACCACCGGCGGCGTAACGGCAAGTTTTTCCATGCTGG
GCGATGTCAATATGGCCGAGCCCAAGGCCCTGATCGGTTTTGCCGGACCGCGCGTCATCGAGCAGACCATCCGGCAGAAA
CTTCCCGAGGGATTCCAGCGTGCCGAGTACCTCCTGGACCACGGCATGGTGGATTTGATCGTGGAGCGTAAGGATATGCG
GGCAAGGCTGGCCCAGATCCTTTCGATGCTCTACCGCCGCTGA

Upstream 100 bases:

>100_bases
AAGATACGACAATTGACTTTGTCGTCGATTTCTGGTACCAGAGGACTTCATTTTTACTAAAAATATCCGGGGCGTTGCTT
GTCCCGACGGAGTGAAAGAT

Downstream 100 bases:

>100_bases
AGCGGAGAGGTGGCGAGCGATTGACCGGCAGGGGCGGAGGTGTTCTCTCCGCCCCTGTTGCTTTCGTGGGTCAAAGCGGT
GGATTTTCCCCCTCTCTTCC

Product: acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha

Products: NA

Alternate protein names: ACCase subunit beta; Acetyl-CoA carboxylase carboxyltransferase subunit beta [H]

Number of amino acids: Translated: 280; Mature: 279

Protein sequence:

>280_residues
MAWFKRDKAPGAADKKVKVPEGLLTKCVSCKANLLTKDLEKNINVCPQCGHHYRISARQRIDLLMDPGSFAEHDAGMTSV
DVLNFKDSKSYQDRIQQAVAKGGSRDAVVCGEGAIDAVPVQLAVFDFSFMGGSMGSVVGEKITRAIERGIEKRTPVIIIS
ASGGARMQESILSLMQMAKTSAALAKLKDLGLPYISILTDPTTGGVTASFSMLGDVNMAEPKALIGFAGPRVIEQTIRQK
LPEGFQRAEYLLDHGMVDLIVERKDMRARLAQILSMLYRR

Sequences:

>Translated_280_residues
MAWFKRDKAPGAADKKVKVPEGLLTKCVSCKANLLTKDLEKNINVCPQCGHHYRISARQRIDLLMDPGSFAEHDAGMTSV
DVLNFKDSKSYQDRIQQAVAKGGSRDAVVCGEGAIDAVPVQLAVFDFSFMGGSMGSVVGEKITRAIERGIEKRTPVIIIS
ASGGARMQESILSLMQMAKTSAALAKLKDLGLPYISILTDPTTGGVTASFSMLGDVNMAEPKALIGFAGPRVIEQTIRQK
LPEGFQRAEYLLDHGMVDLIVERKDMRARLAQILSMLYRR
>Mature_279_residues
AWFKRDKAPGAADKKVKVPEGLLTKCVSCKANLLTKDLEKNINVCPQCGHHYRISARQRIDLLMDPGSFAEHDAGMTSVD
VLNFKDSKSYQDRIQQAVAKGGSRDAVVCGEGAIDAVPVQLAVFDFSFMGGSMGSVVGEKITRAIERGIEKRTPVIIISA
SGGARMQESILSLMQMAKTSAALAKLKDLGLPYISILTDPTTGGVTASFSMLGDVNMAEPKALIGFAGPRVIEQTIRQKL
PEGFQRAEYLLDHGMVDLIVERKDMRARLAQILSMLYRR

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA [H

COG id: COG0777

COG function: function code I; Acetyl-CoA carboxylase beta subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccD/PCCB family [H]

Homologues:

Organism=Homo sapiens, GI119943100, Length=191, Percent_Identity=29.8429319371728, Blast_Score=75, Evalue=6e-14,
Organism=Escherichia coli, GI1788655, Length=277, Percent_Identity=56.3176895306859, Blast_Score=336, Evalue=1e-93,
Organism=Caenorhabditis elegans, GI25147362, Length=190, Percent_Identity=27.8947368421053, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI25147359, Length=190, Percent_Identity=27.8947368421053, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011762 [H]

Pfam domain/function: PF01039 Carboxyl_trans [H]

EC number: =6.4.1.2 [H]

Molecular weight: Translated: 30504; Mature: 30373

Theoretical pI: Translated: 9.42; Mature: 9.42

Prosite motif: PS50980 COA_CT_NTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAWFKRDKAPGAADKKVKVPEGLLTKCVSCKANLLTKDLEKNINVCPQCGHHYRISARQR
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECHHHC
IDLLMDPGSFAEHDAGMTSVDVLNFKDSKSYQDRIQQAVAKGGSRDAVVCGEGAIDAVPV
EEEEECCCCCHHHCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCHHHH
QLAVFDFSFMGGSMGSVVGEKITRAIERGIEKRTPVIIISASGGARMQESILSLMQMAKT
HHEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHH
SAALAKLKDLGLPYISILTDPTTGGVTASFSMLGDVNMAEPKALIGFAGPRVIEQTIRQK
HHHHHHHHHCCCCEEEEEECCCCCCCEEHHHHHCCCCCCCCCHHHCCCCHHHHHHHHHHH
LPEGFQRAEYLLDHGMVDLIVERKDMRARLAQILSMLYRR
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AWFKRDKAPGAADKKVKVPEGLLTKCVSCKANLLTKDLEKNINVCPQCGHHYRISARQR
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECHHHC
IDLLMDPGSFAEHDAGMTSVDVLNFKDSKSYQDRIQQAVAKGGSRDAVVCGEGAIDAVPV
EEEEECCCCCHHHCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCHHHH
QLAVFDFSFMGGSMGSVVGEKITRAIERGIEKRTPVIIISASGGARMQESILSLMQMAKT
HHEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHH
SAALAKLKDLGLPYISILTDPTTGGVTASFSMLGDVNMAEPKALIGFAGPRVIEQTIRQK
HHHHHHHHHCCCCEEEEEECCCCCCCEEHHHHHCCCCCCCCCHHHCCCCHHHHHHHHHHH
LPEGFQRAEYLLDHGMVDLIVERKDMRARLAQILSMLYRR
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA