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The map label for this gene is resA [H]

Identifier: 78223655

GI number: 78223655

Start: 2775127

End: 2775639

Strand: Reverse

Name: resA [H]

Synonym: Gmet_2452

Alternate gene names: 78223655

Gene position: 2775639-2775127 (Counterclockwise)

Preceding gene: 78223656

Following gene: 78223654

Centisome position: 69.44

GC content: 58.87

Gene sequence:

>513_bases
ATGAGAAAGATTTTCCTGATTCTGCCGATCTTGTTCCTGTTGGCCCTTACGGGATGCTCAAAAGAGTCGAAGCCTCCCGT
CGAGGAGAACCCTGCCCCCGATTTCACCCTGAACACCCTGAACGGCGAGGTGGTGAAGCTCTCCGACCTGAAAGGCCAGG
TGGTGATCGTGAACTTCTGGGCCACCTGGTGCCCCCCCTGCCGCGAGGAGATTCCCTCCATGATGCGGCTCAACGCGGCC
ATGGCCGGGAAACCGTTCCGGATGCTCTGCGTCTCCATCGATGAGGGGGGGAAGGTGGCGGTGGAGGAGTTCTTCCGCAA
GACCGGTTTCACTCTGCCGGTGCTTCTGGATGCCGACAAGCGGGTCGGCAAACTCTACGGCACAACGGGTGTCCCCGAGA
CTTTTGTCATCGACCGCCATGGTGTTATACTCAAAAAGGTCGTCGGCGCCATGGAGTGGGACCACCCCGAGGTGATCGCC
TTCCTGAACAACGAACTTAGCAAAGCGAGATAG

Upstream 100 bases:

>100_bases
ACTGGAACCAGAGTTCGGCGGCGCGCTTTCTGCGCATACCGCGTCATACCCTCATCTACCGCATGGAGAAATACTCCATC
ACAACGCCGGAGAGAAAAAA

Downstream 100 bases:

>100_bases
CAAGTAGCAAGTAGCAAGTAGTCAAAATAGCTACTTCACTACTTCACTACCTCGCTACCTCACTACCTCACTACCTCGCT
ATCTCGCTATCTCGCTATCT

Product: thioredoxin family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 170; Mature: 170

Protein sequence:

>170_residues
MRKIFLILPILFLLALTGCSKESKPPVEENPAPDFTLNTLNGEVVKLSDLKGQVVIVNFWATWCPPCREEIPSMMRLNAA
MAGKPFRMLCVSIDEGGKVAVEEFFRKTGFTLPVLLDADKRVGKLYGTTGVPETFVIDRHGVILKKVVGAMEWDHPEVIA
FLNNELSKAR

Sequences:

>Translated_170_residues
MRKIFLILPILFLLALTGCSKESKPPVEENPAPDFTLNTLNGEVVKLSDLKGQVVIVNFWATWCPPCREEIPSMMRLNAA
MAGKPFRMLCVSIDEGGKVAVEEFFRKTGFTLPVLLDADKRVGKLYGTTGVPETFVIDRHGVILKKVVGAMEWDHPEVIA
FLNNELSKAR
>Mature_170_residues
MRKIFLILPILFLLALTGCSKESKPPVEENPAPDFTLNTLNGEVVKLSDLKGQVVIVNFWATWCPPCREEIPSMMRLNAA
MAGKPFRMLCVSIDEGGKVAVEEFFRKTGFTLPVLLDADKRVGKLYGTTGVPETFVIDRHGVILKKVVGAMEWDHPEVIA
FLNNELSKAR

Specific function: Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c; following this reduction heme can be covalent

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein. Note=The thioredoxin-like motif is exposed on the outside of the membrane [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1788523, Length=168, Percent_Identity=27.3809523809524, Blast_Score=65, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00578 AhpC-TSA [H]

EC number: NA

Molecular weight: Translated: 18931; Mature: 18931

Theoretical pI: Translated: 7.94; Mature: 7.94

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKIFLILPILFLLALTGCSKESKPPVEENPAPDFTLNTLNGEVVKLSDLKGQVVIVNFW
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCEEEEECCCCCEEEEEEC
ATWCPPCREEIPSMMRLNAAMAGKPFRMLCVSIDEGGKVAVEEFFRKTGFTLPVLLDADK
CCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHCCCEEEEEECCCC
RVGKLYGTTGVPETFVIDRHGVILKKVVGAMEWDHPEVIAFLNNELSKAR
HHHHHHCCCCCCCEEEEECCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MRKIFLILPILFLLALTGCSKESKPPVEENPAPDFTLNTLNGEVVKLSDLKGQVVIVNFW
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCEEEEECCCCCEEEEEEC
ATWCPPCREEIPSMMRLNAAMAGKPFRMLCVSIDEGGKVAVEEFFRKTGFTLPVLLDADK
CCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHCCCEEEEEECCCC
RVGKLYGTTGVPETFVIDRHGVILKKVVGAMEWDHPEVIAFLNNELSKAR
HHHHHHCCCCCCCEEEEECCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715; 12637552 [H]