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The map label for this gene is ccdA [H]

Identifier: 78223654

GI number: 78223654

Start: 2774253

End: 2774981

Strand: Reverse

Name: ccdA [H]

Synonym: Gmet_2451

Alternate gene names: 78223654

Gene position: 2774981-2774253 (Counterclockwise)

Preceding gene: 78223655

Following gene: 78223653

Centisome position: 69.42

GC content: 57.75

Gene sequence:

>729_bases
ATGGATTCATCCCACGTTACTTTCTTAGGCGCGTTCATTGCGGGGTTCCTCTCGTTCCTCTCTCCGTGCGTGCTGCCGCT
CATCCCCTCCTTTATCACCTACATCACGGGGCTTTCCTTCTCCGATCTCCAGGCGGAGCACCCGAGCCACAAGGTCCGGC
AGCAGACCATCGTCCATACCCTCCTCTTCATTGCCGGATTCACCACTGTCTTCGTCCTGCTGGGGGCCTCGGCAACCTTT
ATCGGCGGGTTTCTCCACGAGCACATGGACATTATCCGGAAGGTTGGAGGAATACTGATCATCATCTTCGGCATCCATGT
CACCGGTCTGGTCCCCATTCATCTGCTGCTGGGAGAGAAGCGGGTCACCGTCCACCGCAAACCGGCCGGCTATCTGGGGA
GCTTCGTTGTCGGGCTTGCCTTTGCCGCCGGGTGGACTCCCTGTATCGGCCCCATCCTCGCCTCCATCCTCATGGTGGCC
ACCACGGAGGAGACGGTTTCCCGCGGCGTTCTTCTCCTCCTGACCTATTCCATGGGGCTTGCCATTCCCTTTTTCCTCTC
GTCCCTGGCCATGCACCAGTTCCTCGTCGTTTTCAACCGCTTCAAGAAGCATATCCGGATCTTCGAGATTATTACCGGCG
TCTTCCTGATCATCGTCGGGGTCATGATTTTCAGCAACTACCTGAGTATCCTGTCGCGGTTCAGCATGAAGTGGCTCGGG
GGGGAGTGA

Upstream 100 bases:

>100_bases
ACTACCTCGCTACCTCACTACCTCACTACCTCGCTATCTCGCTATCTCGCTATCTCGCTATCTCGCTATCTCGCTATCTC
GCTATCTCGCAGAGGTCTTC

Downstream 100 bases:

>100_bases
CATCATGGCGGGGACAGGCGCCTCAATCCAGTTGACCGTCGTGGATCTGGACGCCACCGAGGCGTTCTACGCGGGTATCC
TGGAGCTTGATGTAATGAGG

Product: cytochrome c biogenesis protein, transmembrane region

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MDSSHVTFLGAFIAGFLSFLSPCVLPLIPSFITYITGLSFSDLQAEHPSHKVRQQTIVHTLLFIAGFTTVFVLLGASATF
IGGFLHEHMDIIRKVGGILIIIFGIHVTGLVPIHLLLGEKRVTVHRKPAGYLGSFVVGLAFAAGWTPCIGPILASILMVA
TTEETVSRGVLLLLTYSMGLAIPFFLSSLAMHQFLVVFNRFKKHIRIFEIITGVFLIIVGVMIFSNYLSILSRFSMKWLG
GE

Sequences:

>Translated_242_residues
MDSSHVTFLGAFIAGFLSFLSPCVLPLIPSFITYITGLSFSDLQAEHPSHKVRQQTIVHTLLFIAGFTTVFVLLGASATF
IGGFLHEHMDIIRKVGGILIIIFGIHVTGLVPIHLLLGEKRVTVHRKPAGYLGSFVVGLAFAAGWTPCIGPILASILMVA
TTEETVSRGVLLLLTYSMGLAIPFFLSSLAMHQFLVVFNRFKKHIRIFEIITGVFLIIVGVMIFSNYLSILSRFSMKWLG
GE
>Mature_242_residues
MDSSHVTFLGAFIAGFLSFLSPCVLPLIPSFITYITGLSFSDLQAEHPSHKVRQQTIVHTLLFIAGFTTVFVLLGASATF
IGGFLHEHMDIIRKVGGILIIIFGIHVTGLVPIHLLLGEKRVTVHRKPAGYLGSFVVGLAFAAGWTPCIGPILASILMVA
TTEETVSRGVLLLLTYSMGLAIPFFLSSLAMHQFLVVFNRFKKHIRIFEIITGVFLIIVGVMIFSNYLSILSRFSMKWLG
GE

Specific function: Cytochrome c oxidase activity is partially restored by mutations in bdbC or bdbD that are defective in the synthesis of disulfide bond containing proteins. The same mutations abrogate the need for CcdA in sporulation [H]

COG id: COG0785

COG function: function code O; Cytochrome c biogenesis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DsbD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834 [H]

Pfam domain/function: PF02683 DsbD [H]

EC number: NA

Molecular weight: Translated: 26523; Mature: 26523

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CC
>Mature Secondary Structure
MDSSHVTFLGAFIAGFLSFLSPCVLPLIPSFITYITGLSFSDLQAEHPSHKVRQQTIVHT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHH
LLFIAGFTTVFVLLGASATFIGGFLHEHMDIIRKVGGILIIIFGIHVTGLVPIHLLLGEK
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RVTVHRKPAGYLGSFVVGLAFAAGWTPCIGPILASILMVATTEETVSRGVLLLLTYSMGL
CEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
AIPFFLSSLAMHQFLVVFNRFKKHIRIFEIITGVFLIIVGVMIFSNYLSILSRFSMKWLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GE
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969507; 9068642; 9384377; 10781554; 11844773 [H]