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The map label for this gene is lpxK [H]

Identifier: 78223549

GI number: 78223549

Start: 2653194

End: 2653382

Strand: Reverse

Name: lpxK [H]

Synonym: Gmet_2346

Alternate gene names: 78223549

Gene position: 2653382-2653194 (Counterclockwise)

Preceding gene: 78223550

Following gene: 78223548

Centisome position: 66.38

GC content: 55.03

Gene sequence:

>189_bases
ATGGCATTATCAAGCGAATTGCTCAAGATTCTGGCCTGTCCTCAGTGCAAGGGGGAAGTAGTCTTCCAGGACGACGAGGT
GGGGCTTGTCTGCGATTCATGTCGGCTCGTCTACCCCGTGCGGGACGGAATTCCGGTCATGCTGGTGGACGAAGCGGAAA
AAATTGGAGAAGCGGGGAAACGCGATTAG

Upstream 100 bases:

>100_bases
GCTGGGGATTGTCTATGCGGCGGTGCTGGAGATGAGCCTTATGGATCCGAAACCCCTCGAAACAGCCATCGACAAAGTGC
TTTAAAAGGAGATGCCCTCT

Downstream 100 bases:

>100_bases
TGACCGACAGCATATCGGCTCTCGATAAATCGGCTATACGCACCATTCTCGTCCGGGCGGTGAACTGGCTCGGCGATGCG
GTCATGACCACGCCTGCTCT

Product: hypothetical protein

Products: NA

Alternate protein names: Lipid A 4'-kinase [H]

Number of amino acids: Translated: 62; Mature: 61

Protein sequence:

>62_residues
MALSSELLKILACPQCKGEVVFQDDEVGLVCDSCRLVYPVRDGIPVMLVDEAEKIGEAGKRD

Sequences:

>Translated_62_residues
MALSSELLKILACPQCKGEVVFQDDEVGLVCDSCRLVYPVRDGIPVMLVDEAEKIGEAGKRD
>Mature_61_residues
ALSSELLKILACPQCKGEVVFQDDEVGLVCDSCRLVYPVRDGIPVMLVDEAEKIGEAGKRD

Specific function: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) [H]

COG id: COG2835

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the UPF0434 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003758
- InterPro:   IPR005651 [H]

Pfam domain/function: PF02606 LpxK; PF03966 Trm112p [H]

EC number: =2.7.1.130 [H]

Molecular weight: Translated: 6753; Mature: 6622

Theoretical pI: Translated: 4.18; Mature: 4.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

6.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
9.7 %Cys+Met (Translated Protein)
6.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
8.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALSSELLKILACPQCKGEVVFQDDEVGLVCDSCRLVYPVRDGIPVMLVDEAEKIGEAGK
CCCHHHHHHHHCCCCCCCCEEEECCCCCEEECCCEEEEEECCCCCEEEECCCHHHCCCCC
RD
CC
>Mature Secondary Structure 
ALSSELLKILACPQCKGEVVFQDDEVGLVCDSCRLVYPVRDGIPVMLVDEAEKIGEAGK
CCHHHHHHHHCCCCCCCCEEEECCCCCEEECCCEEEEEECCCCCEEEECCCHHHCCCCC
RD
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA