Click here to switch to the map view.

The map label for this gene is sucD [H]

Identifier: 78223464

GI number: 78223464

Start: 2560315

End: 2561190

Strand: Reverse

Name: sucD [H]

Synonym: Gmet_2260

Alternate gene names: 78223464

Gene position: 2561190-2560315 (Counterclockwise)

Preceding gene: 78223465

Following gene: 78223463

Centisome position: 64.07

GC content: 62.9

Gene sequence:

>876_bases
ATGAGCATCCTTATCAATAAAGACACCAAAGTCATCACCCAGGGGCTCGGTGCCACCGGCCTCTTCCACGCCAACGGGGC
CCGCGAGTACGGCACCCAGATGGTCGGGGGTGTCACCCCCGGCAAAGGGGGCACCGTCATCGACGGCTTCCCCGTCTATG
ACACCGTGCGGGAAGCGGTAGCCAAGACCGGGGCCACCGCCTCCGTCATCTACGTTCCACCCCCTTTTGCTGCCGACTCC
ATCATGGAGGCGGTAGACGCGGGACTCGACCTCGTCATCTGCATCACCGAAGGGATACCGGTCCTGGACATGGTGAAAGT
AAAGCAGTACATGCAGGGGAAGAAGACCCGCCTCGTTGGCCCCAACTGCCCCGGGGTCATCACCCCCGGCCAGTGCAAGA
TCGGGATCATGCCGGGGTACATCCACAAGCCGGGGAAAGTAGGGGTTGTCTCCCGCAGTGGCACCCTCACCTACGAAGCG
GTATGGCAGCTGACCAACGTGGGGCTGGGGCAGTCCACCTGCGTCGGCATCGGGGGTGACCCGGTCAACGGCACCAACCA
CGTGGACGTACTCCGGATGTTCGAGGAAGACCCGGACACCGAGGCAGTGATCATGATCGGCGAGATCGGGGGTAACTCCG
AGGAAGAAGGGGCGCGGTTCGTCAAGGAGCACATGACCAAGCCGGTGGCGGCGTACATTGCCGGGGTCACCGCTCCTCCG
GGTAAGCGGATGGGTCATGCGGGTGCCATCATCTCTGGCGGCAAGGGGACGGCGACGGAAAAGGTGGCCATTCTGGAAGA
GTGCGGCATCAGTGTAGCCCAGAGCCCCGCCGACATGGCCAAAGCGCTCCTCAAGATCTACAAGCCGAGGAATTGA

Upstream 100 bases:

>100_bases
AAATGCTGGCCGAGAGCGGCCTCAACATAGTCGCCGCCGACGGTATGGCCGATGGCGCCCAAAAAATCGTCCAGGCCGTT
GCCTGAGGAGGGATAGACAG

Downstream 100 bases:

>100_bases
AAACAACTAATCTAGAAACGGCAGTTGAAATGTGGTCTGCAGGGAAGCGGAATGAGCGCAGGACTTCTCCAACTGCCAAA
TCTAGGACTACCGTTGGTGC

Product: succinyl-CoA synthetase (ADP-forming) subunit alpha

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha; Vegetative protein 239; VEG239 [H]

Number of amino acids: Translated: 291; Mature: 290

Protein sequence:

>291_residues
MSILINKDTKVITQGLGATGLFHANGAREYGTQMVGGVTPGKGGTVIDGFPVYDTVREAVAKTGATASVIYVPPPFAADS
IMEAVDAGLDLVICITEGIPVLDMVKVKQYMQGKKTRLVGPNCPGVITPGQCKIGIMPGYIHKPGKVGVVSRSGTLTYEA
VWQLTNVGLGQSTCVGIGGDPVNGTNHVDVLRMFEEDPDTEAVIMIGEIGGNSEEEGARFVKEHMTKPVAAYIAGVTAPP
GKRMGHAGAIISGGKGTATEKVAILEECGISVAQSPADMAKALLKIYKPRN

Sequences:

>Translated_291_residues
MSILINKDTKVITQGLGATGLFHANGAREYGTQMVGGVTPGKGGTVIDGFPVYDTVREAVAKTGATASVIYVPPPFAADS
IMEAVDAGLDLVICITEGIPVLDMVKVKQYMQGKKTRLVGPNCPGVITPGQCKIGIMPGYIHKPGKVGVVSRSGTLTYEA
VWQLTNVGLGQSTCVGIGGDPVNGTNHVDVLRMFEEDPDTEAVIMIGEIGGNSEEEGARFVKEHMTKPVAAYIAGVTAPP
GKRMGHAGAIISGGKGTATEKVAILEECGISVAQSPADMAKALLKIYKPRN
>Mature_290_residues
SILINKDTKVITQGLGATGLFHANGAREYGTQMVGGVTPGKGGTVIDGFPVYDTVREAVAKTGATASVIYVPPPFAADSI
MEAVDAGLDLVICITEGIPVLDMVKVKQYMQGKKTRLVGPNCPGVITPGQCKIGIMPGYIHKPGKVGVVSRSGTLTYEAV
WQLTNVGLGQSTCVGIGGDPVNGTNHVDVLRMFEEDPDTEAVIMIGEIGGNSEEEGARFVKEHMTKPVAAYIAGVTAPPG
KRMGHAGAIISGGKGTATEKVAILEECGISVAQSPADMAKALLKIYKPRN

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=294, Percent_Identity=60.5442176870748, Blast_Score=310, Evalue=1e-84,
Organism=Homo sapiens, GI38569423, Length=252, Percent_Identity=29.3650793650794, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI38569421, Length=252, Percent_Identity=29.3650793650794, Blast_Score=94, Evalue=2e-19,
Organism=Escherichia coli, GI1786949, Length=289, Percent_Identity=68.1660899653979, Blast_Score=399, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI17550194, Length=292, Percent_Identity=59.5890410958904, Blast_Score=324, Evalue=3e-89,
Organism=Caenorhabditis elegans, GI17553126, Length=293, Percent_Identity=56.9965870307167, Blast_Score=306, Evalue=8e-84,
Organism=Caenorhabditis elegans, GI17557344, Length=257, Percent_Identity=28.7937743190661, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17551266, Length=256, Percent_Identity=28.125, Blast_Score=84, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6324716, Length=296, Percent_Identity=49.3243243243243, Blast_Score=275, Evalue=4e-75,
Organism=Drosophila melanogaster, GI21356559, Length=290, Percent_Identity=55.5172413793103, Blast_Score=320, Evalue=7e-88,
Organism=Drosophila melanogaster, GI28574296, Length=293, Percent_Identity=58.3617747440273, Blast_Score=304, Evalue=6e-83,
Organism=Drosophila melanogaster, GI281363477, Length=251, Percent_Identity=27.4900398406374, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI281363475, Length=251, Percent_Identity=27.4900398406374, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI281363473, Length=251, Percent_Identity=27.4900398406374, Blast_Score=85, Evalue=5e-17,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 30250; Mature: 30119

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILINKDTKVITQGLGATGLFHANGAREYGTQMVGGVTPGKGGTVIDGFPVYDTVREAV
CEEEECCCHHHHHHCCCCCEEEECCCCHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHHH
AKTGATASVIYVPPPFAADSIMEAVDAGLDLVICITEGIPVLDMVKVKQYMQGKKTRLVG
HHCCCCEEEEEECCCCCHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHCCCCEEEEC
PNCPGVITPGQCKIGIMPGYIHKPGKVGVVSRSGTLTYEAVWQLTNVGLGQSTCVGIGGD
CCCCCEECCCCEEEEECCCCEECCCCEEEEECCCCEEHHHHHHHHHCCCCCCEEEECCCC
PVNGTNHVDVLRMFEEDPDTEAVIMIGEIGGNSEEEGARFVKEHMTKPVAAYIAGVTAPP
CCCCCCHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHCCCCCC
GKRMGHAGAIISGGKGTATEKVAILEECGISVAQSPADMAKALLKIYKPRN
CCCCCCCCEEEECCCCCCHHHHHHHHHCCCHHCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SILINKDTKVITQGLGATGLFHANGAREYGTQMVGGVTPGKGGTVIDGFPVYDTVREAV
EEEECCCHHHHHHCCCCCEEEECCCCHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHHH
AKTGATASVIYVPPPFAADSIMEAVDAGLDLVICITEGIPVLDMVKVKQYMQGKKTRLVG
HHCCCCEEEEEECCCCCHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHCCCCEEEEC
PNCPGVITPGQCKIGIMPGYIHKPGKVGVVSRSGTLTYEAVWQLTNVGLGQSTCVGIGGD
CCCCCEECCCCEEEEECCCCEECCCCEEEEECCCCEEHHHHHHHHHCCCCCCEEEECCCC
PVNGTNHVDVLRMFEEDPDTEAVIMIGEIGGNSEEEGARFVKEHMTKPVAAYIAGVTAPP
CCCCCCHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHCCCCCC
GKRMGHAGAIISGGKGTATEKVAILEECGISVAQSPADMAKALLKIYKPRN
CCCCCCCCEEEECCCCCCHHHHHHHHHCCCHHCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 9298659 [H]