Click here to switch to the map view.

The map label for this gene is sucC [H]

Identifier: 78223465

GI number: 78223465

Start: 2561205

End: 2562365

Strand: Reverse

Name: sucC [H]

Synonym: Gmet_2261

Alternate gene names: 78223465

Gene position: 2562365-2561205 (Counterclockwise)

Preceding gene: 78223466

Following gene: 78223464

Centisome position: 64.1

GC content: 61.67

Gene sequence:

>1161_bases
ATGAACATTCACGAGTATCAGGCAAAGGCGATACTAAGGAATTTCGGCGTACCTGTCCCGGACGGGCATGTGTGCTACAA
CGGGGCGAGCGCGCGGGAGTGGGCGAAGCGGCTGGGGGATGGCCCCTGGGTGGTGAAGGCCCAGATCCATGCCGGTGGGC
GCGGCAAGGGCGGAGGGGTCAAACTGGCCCGCACCAACCAGGAAGTCCAGCAAATAGCCCGGGACATGCTGGGGATGACG
CTCAGGACCCATCAGACCGGGCCGGAAGGGAAAGTGGTCACCCGGGTCCTGGTGGAAAACGGCTGCAACATCGACCGGGA
ACTGTACGTGAGCCTTCTGGTGGACCGGGCCACCTCCCGGGTCACCGTCATGGCCTCCACCGAAGGGGGAATGGACATCG
AAGAGGTGGCGGCAAAGACCCCGGAGAAGATCTTCCGGGAGGCGATCGATCCCCTGGTGGGGCTCACCCCGTTCCAGAGC
CGCAACCTCGCCTTCAGCCTGGGGCTGACGGGGAAGCTCACCCCCAAGGCGGTCAACCTGCTGGAAGGGCTCTACACCAC
CTTTCTCGCCTGTGACTGTTCCCTTCTGGAGATCAACCCCCTGGTGGTCACCAAGGAAGGAGACCTCCTCGCCCTGGATG
CCAAATTCGGCTTCGACGACAATGCTGTCTTCAAACATCCGGGGATAGCGGATTTCAGGGATTACAACGAAGAAGACCCC
AACGAGGTGGAAGCGTCCCAGCACGACCTCTCCTACGTATCCCTGAACGGCAACATCGGCTGCCTGGTCAACGGCGCCGG
TCTGGCCATGGCCACCATGGACATCATCAAATTCTCCGGCGGCGAGCCGGCCAACTTCCTGGACGTGGGAGGCGGGGCCA
CCATTGAGCGGGTCACCGAGGCGTTCAAGATCATCCTTTCCGACAAGAACGTCAAAGGAATCTTCGTCAACATCTTCGGC
GGCATCATGAAGTGCGACGTCATCGCCACCGGGGTCATCGAGGCGGCCCGGCAGGTATCGCTCCAGGTGCCTTTGGTGGT
ACGTCTCGAAGGGACCAACGTGGAAATCGGCAAGAAAATGCTGGCCGAGAGCGGCCTCAACATAGTCGCCGCCGACGGTA
TGGCCGATGGCGCCCAAAAAATCGTCCAGGCCGTTGCCTGA

Upstream 100 bases:

>100_bases
TTCCCGCCCTGACGGCGAAACTGTAATTCTAAAAAACAAGTTTTTTGAGTGTGATAGTTGGTAAACGGAGCAGTTACTAT
TTTATTGATTGGAGCTAACG

Downstream 100 bases:

>100_bases
GGAGGGATAGACAGATGAGCATCCTTATCAATAAAGACACCAAAGTCATCACCCAGGGGCTCGGTGCCACCGGCCTCTTC
CACGCCAACGGGGCCCGCGA

Product: succinyl-CoA synthetase (ADP-forming) beta subunit

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MNIHEYQAKAILRNFGVPVPDGHVCYNGASAREWAKRLGDGPWVVKAQIHAGGRGKGGGVKLARTNQEVQQIARDMLGMT
LRTHQTGPEGKVVTRVLVENGCNIDRELYVSLLVDRATSRVTVMASTEGGMDIEEVAAKTPEKIFREAIDPLVGLTPFQS
RNLAFSLGLTGKLTPKAVNLLEGLYTTFLACDCSLLEINPLVVTKEGDLLALDAKFGFDDNAVFKHPGIADFRDYNEEDP
NEVEASQHDLSYVSLNGNIGCLVNGAGLAMATMDIIKFSGGEPANFLDVGGGATIERVTEAFKIILSDKNVKGIFVNIFG
GIMKCDVIATGVIEAARQVSLQVPLVVRLEGTNVEIGKKMLAESGLNIVAADGMADGAQKIVQAVA

Sequences:

>Translated_386_residues
MNIHEYQAKAILRNFGVPVPDGHVCYNGASAREWAKRLGDGPWVVKAQIHAGGRGKGGGVKLARTNQEVQQIARDMLGMT
LRTHQTGPEGKVVTRVLVENGCNIDRELYVSLLVDRATSRVTVMASTEGGMDIEEVAAKTPEKIFREAIDPLVGLTPFQS
RNLAFSLGLTGKLTPKAVNLLEGLYTTFLACDCSLLEINPLVVTKEGDLLALDAKFGFDDNAVFKHPGIADFRDYNEEDP
NEVEASQHDLSYVSLNGNIGCLVNGAGLAMATMDIIKFSGGEPANFLDVGGGATIERVTEAFKIILSDKNVKGIFVNIFG
GIMKCDVIATGVIEAARQVSLQVPLVVRLEGTNVEIGKKMLAESGLNIVAADGMADGAQKIVQAVA
>Mature_386_residues
MNIHEYQAKAILRNFGVPVPDGHVCYNGASAREWAKRLGDGPWVVKAQIHAGGRGKGGGVKLARTNQEVQQIARDMLGMT
LRTHQTGPEGKVVTRVLVENGCNIDRELYVSLLVDRATSRVTVMASTEGGMDIEEVAAKTPEKIFREAIDPLVGLTPFQS
RNLAFSLGLTGKLTPKAVNLLEGLYTTFLACDCSLLEINPLVVTKEGDLLALDAKFGFDDNAVFKHPGIADFRDYNEEDP
NEVEASQHDLSYVSLNGNIGCLVNGAGLAMATMDIIKFSGGEPANFLDVGGGATIERVTEAFKIILSDKNVKGIFVNIFG
GIMKCDVIATGVIEAARQVSLQVPLVVRLEGTNVEIGKKMLAESGLNIVAADGMADGAQKIVQAVA

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=390, Percent_Identity=44.3589743589744, Blast_Score=344, Evalue=9e-95,
Organism=Homo sapiens, GI157779135, Length=383, Percent_Identity=46.2140992167102, Blast_Score=332, Evalue=3e-91,
Organism=Homo sapiens, GI294862256, Length=362, Percent_Identity=46.4088397790055, Blast_Score=317, Evalue=9e-87,
Organism=Escherichia coli, GI1786948, Length=385, Percent_Identity=56.3636363636364, Blast_Score=441, Evalue=1e-125,
Organism=Caenorhabditis elegans, GI17567829, Length=389, Percent_Identity=46.5295629820051, Blast_Score=340, Evalue=5e-94,
Organism=Caenorhabditis elegans, GI17539378, Length=394, Percent_Identity=45.6852791878173, Blast_Score=340, Evalue=7e-94,
Organism=Saccharomyces cerevisiae, GI6321683, Length=393, Percent_Identity=44.7837150127226, Blast_Score=356, Evalue=3e-99,
Organism=Drosophila melanogaster, GI161078106, Length=395, Percent_Identity=45.3164556962025, Blast_Score=328, Evalue=4e-90,
Organism=Drosophila melanogaster, GI24645208, Length=395, Percent_Identity=45.3164556962025, Blast_Score=328, Evalue=4e-90,
Organism=Drosophila melanogaster, GI281361397, Length=396, Percent_Identity=45.4545454545455, Blast_Score=326, Evalue=2e-89,
Organism=Drosophila melanogaster, GI281361395, Length=396, Percent_Identity=45.4545454545455, Blast_Score=326, Evalue=2e-89,
Organism=Drosophila melanogaster, GI21356231, Length=396, Percent_Identity=45.4545454545455, Blast_Score=321, Evalue=5e-88,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 41268; Mature: 41268

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS50975 ATP_GRASP ; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIHEYQAKAILRNFGVPVPDGHVCYNGASAREWAKRLGDGPWVVKAQIHAGGRGKGGGV
CCCHHHHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHCCCCCEEEEEEEECCCCCCCCCE
KLARTNQEVQQIARDMLGMTLRTHQTGPEGKVVTRVLVENGCNIDRELYVSLLVDRATSR
EEEECCHHHHHHHHHHHCCEEEECCCCCCCHHHHHEEHHCCCCCCHHHHHHHHHHCCCCE
VTVMASTEGGMDIEEVAAKTPEKIFREAIDPLVGLTPFQSRNLAFSLGLTGKLTPKAVNL
EEEEEECCCCCCHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCHHHHHH
LEGLYTTFLACDCSLLEINPLVVTKEGDLLALDAKFGFDDNAVFKHPGIADFRDYNEEDP
HHHHHHHHHHCCCEEEEECEEEEECCCCEEEEEECCCCCCCCEECCCCCCHHHCCCCCCC
NEVEASQHDLSYVSLNGNIGCLVNGAGLAMATMDIIKFSGGEPANFLDVGGGATIERVTE
CHHCCCCCCCEEEEECCCEEEEEECCCHHHHHHHHHEECCCCCCCEEECCCCCHHHHHHH
AFKIILSDKNVKGIFVNIFGGIMKCDVIATGVIEAARQVSLQVPLVVRLEGTNVEIGKKM
HHHEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCEEECCEEEEEECCCCHHHHHH
LAESGLNIVAADGMADGAQKIVQAVA
HHHCCCCEEEECCCCHHHHHHHHHCC
>Mature Secondary Structure
MNIHEYQAKAILRNFGVPVPDGHVCYNGASAREWAKRLGDGPWVVKAQIHAGGRGKGGGV
CCCHHHHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHCCCCCEEEEEEEECCCCCCCCCE
KLARTNQEVQQIARDMLGMTLRTHQTGPEGKVVTRVLVENGCNIDRELYVSLLVDRATSR
EEEECCHHHHHHHHHHHCCEEEECCCCCCCHHHHHEEHHCCCCCCHHHHHHHHHHCCCCE
VTVMASTEGGMDIEEVAAKTPEKIFREAIDPLVGLTPFQSRNLAFSLGLTGKLTPKAVNL
EEEEEECCCCCCHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCHHHHHH
LEGLYTTFLACDCSLLEINPLVVTKEGDLLALDAKFGFDDNAVFKHPGIADFRDYNEEDP
HHHHHHHHHHCCCEEEEECEEEEECCCCEEEEEECCCCCCCCEECCCCCCHHHCCCCCCC
NEVEASQHDLSYVSLNGNIGCLVNGAGLAMATMDIIKFSGGEPANFLDVGGGATIERVTE
CHHCCCCCCCEEEEECCCEEEEEECCCHHHHHHHHHEECCCCCCCEEECCCCCHHHHHHH
AFKIILSDKNVKGIFVNIFGGIMKCDVIATGVIEAARQVSLQVPLVVRLEGTNVEIGKKM
HHHEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCEEECCEEEEEECCCCHHHHHH
LAESGLNIVAADGMADGAQKIVQAVA
HHHCCCCEEEECCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA