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The map label for this gene is nreC [H]

Identifier: 78223365

GI number: 78223365

Start: 2431425

End: 2432057

Strand: Reverse

Name: nreC [H]

Synonym: Gmet_2158

Alternate gene names: 78223365

Gene position: 2432057-2431425 (Counterclockwise)

Preceding gene: 78223366

Following gene: 78223364

Centisome position: 60.84

GC content: 54.5

Gene sequence:

>633_bases
ATGAGCACCAGGATACTTGTAGCCGATGATCACGCAATCTTCAGGGAAGGGCTCAAGCAGGTTATTGGCACCACGGTGGA
CATGAGCGTTGTCGACGAAGCGGTCGACGGCAAGGAGTTGCTGAACAAGATACAGGCCAATGATTACGACATGGTGATCC
TCGATATCACCATGCCGGGCAGAAACGGACTCGATGTCCTGACGGAGATGAAAAGCATCAAACCGAAACTGCCGGTCCTC
GTCATGAGCATGCACCCCGAGGAGCAGTACGCGCTCCGTGCGTATAAATCGGGGGCAGCGGGCTACCTGAACAAGGGAAG
CGCTTCCAATGAACTGCTCGATGCCCTGCATAAGATTTCCATGGGGAAAAAATATGTGAGCTCGGCCCTGGCGGAGTCTC
TGGTATCCGGTCTCAGTGATCATAACCAGCAGGATCTCCTCCAGAGTCTCTCCAACAGGGAGTATCAGGTGATGAGCATG
ATCGCCTCAGGCAAGACGGTCGGCAAGATCGCCACCGAGCTTTCCCTGAGCGTGAAGACCGTCAGTACCTACCGGGCCCA
CATCCTGCGCAAGCTGAACATGAAAAACAACGCGGAACTGACCCGCTTCGTCATCGAGAACAAGTTGATCTGA

Upstream 100 bases:

>100_bases
CGGGCGGAGGCGTTTGGAGGGAGACTGAGGATATGCGGCTCTTCGCGCCAGGGGACCACAGTGGTTGCACGGATTCCATT
AGCCAGGGAAGGAGACGTTG

Downstream 100 bases:

>100_bases
TGGGTTCATGGGAAAGGTCTGGCGATGTCACTGGCCCAATCCATAGTTGTTGTTGCCGAACCGAGCCATTCCGATCTGTA
TGACTTGCTGGCAGTCGGCA

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: Nitrogen regulation protein C [H]

Number of amino acids: Translated: 210; Mature: 209

Protein sequence:

>210_residues
MSTRILVADDHAIFREGLKQVIGTTVDMSVVDEAVDGKELLNKIQANDYDMVILDITMPGRNGLDVLTEMKSIKPKLPVL
VMSMHPEEQYALRAYKSGAAGYLNKGSASNELLDALHKISMGKKYVSSALAESLVSGLSDHNQQDLLQSLSNREYQVMSM
IASGKTVGKIATELSLSVKTVSTYRAHILRKLNMKNNAELTRFVIENKLI

Sequences:

>Translated_210_residues
MSTRILVADDHAIFREGLKQVIGTTVDMSVVDEAVDGKELLNKIQANDYDMVILDITMPGRNGLDVLTEMKSIKPKLPVL
VMSMHPEEQYALRAYKSGAAGYLNKGSASNELLDALHKISMGKKYVSSALAESLVSGLSDHNQQDLLQSLSNREYQVMSM
IASGKTVGKIATELSLSVKTVSTYRAHILRKLNMKNNAELTRFVIENKLI
>Mature_209_residues
STRILVADDHAIFREGLKQVIGTTVDMSVVDEAVDGKELLNKIQANDYDMVILDITMPGRNGLDVLTEMKSIKPKLPVLV
MSMHPEEQYALRAYKSGAAGYLNKGSASNELLDALHKISMGKKYVSSALAESLVSGLSDHNQQDLLQSLSNREYQVMSMI
ASGKTVGKIATELSLSVKTVSTYRAHILRKLNMKNNAELTRFVIENKLI

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. Phosphorylated nreC binds to a GC-rich palindromic sequence at the promoters of the nitrate (narGHJI) and nit

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=207, Percent_Identity=31.8840579710145, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI1790102, Length=200, Percent_Identity=34.5, Blast_Score=120, Evalue=8e-29,
Organism=Escherichia coli, GI1786747, Length=201, Percent_Identity=28.3582089552239, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1788521, Length=207, Percent_Identity=28.5024154589372, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1788712, Length=204, Percent_Identity=27.9411764705882, Blast_Score=87, Evalue=7e-19,
Organism=Escherichia coli, GI1787473, Length=189, Percent_Identity=35.4497354497354, Blast_Score=86, Evalue=1e-18,
Organism=Escherichia coli, GI1788546, Length=203, Percent_Identity=28.0788177339901, Blast_Score=76, Evalue=1e-15,
Organism=Escherichia coli, GI1788191, Length=118, Percent_Identity=32.2033898305085, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23156; Mature: 23025

Theoretical pI: Translated: 8.75; Mature: 8.75

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTRILVADDHAIFREGLKQVIGTTVDMSVVDEAVDGKELLNKIQANDYDMVILDITMPG
CCCEEEEECCHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHCCCCCCEEEEEEECCC
RNGLDVLTEMKSIKPKLPVLVMSMHPEEQYALRAYKSGAAGYLNKGSASNELLDALHKIS
CCCHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHH
MGKKYVSSALAESLVSGLSDHNQQDLLQSLSNREYQVMSMIASGKTVGKIATELSLSVKT
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHH
VSTYRAHILRKLNMKNNAELTRFVIENKLI
HHHHHHHHHHHHCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
STRILVADDHAIFREGLKQVIGTTVDMSVVDEAVDGKELLNKIQANDYDMVILDITMPG
CCEEEEECCHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHCCCCCCEEEEEEECCC
RNGLDVLTEMKSIKPKLPVLVMSMHPEEQYALRAYKSGAAGYLNKGSASNELLDALHKIS
CCCHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHH
MGKKYVSSALAESLVSGLSDHNQQDLLQSLSNREYQVMSMIASGKTVGKIATELSLSVKT
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHH
VSTYRAHILRKLNMKNNAELTRFVIENKLI
HHHHHHHHHHHHCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA