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The map label for this gene is ribD [H]

Identifier: 78222833

GI number: 78222833

Start: 1821495

End: 1822607

Strand: Direct

Name: ribD [H]

Synonym: Gmet_1624

Alternate gene names: 78222833

Gene position: 1821495-1822607 (Clockwise)

Preceding gene: 78222832

Following gene: 78222834

Centisome position: 45.57

GC content: 63.16

Gene sequence:

>1113_bases
ATGGATGTGTCTCCCGAAAAGATCATGAAGCGTGCTCTGGCGCTGGCAAGGCGGGGCAAGGGCAAAACGTCTCCGAATCC
GGCGGTGGGGTGCGTCATCGTGCGGGACGGTGCAATCGTCGGCGAAGGGTGGCACCGGAAGGCCGGCACCCCCCATGCCG
AGGTCCATGCCCTGCGGCAGGCCGGCGAGCTGGCCCGGGGCGCCGATGTCTACGTGACTCTGGAGCCCTGCTCCCACTTC
GGCAAGACTCCCCCGTGTGCCGATGCGCTGGTCGAGGCAGGGGTGGGGCGCGTGTTCGTCGGCATGGTGGACCCGAATCC
GAAGGTTTCCGGGCGCGGCATCGAGCGGCTTCGGGTTGCCGGCATCGAGGTGGTTACCGGGATACGGGAGGCGGAGTGCC
GCCGGCTTAACGAGCCATTCGTGAAACACGTGACCACCGGGCTTCCCTTTGTGATCCTCAAGTCGGCCATGACCATGGAC
GGCAAGACCGCTACCGCTTCGGGCGATTCGCGCTGGATAACCAACGAAAAATCAAGGCGCTACGTTCATAAACTTCGATC
AATGGTCGATGCGATAATGGTCGGTGTCGGCACTGTCTTGGCCGATGACCCCCAGCTTACGGCGCGAATCCCGCGGGGGA
AGGATCCTGTCCGGGTTGTGGTGGACAGTTCCCTCAGAATCCCCTCTGGTGCCCGGATGCTCCACCAGGAGTCCCCGGCA
ACAACCGTCGTTGCCACCGTCTCGGAAGACCGAAACCGGATCGTGAAGCTGGAATCTGCAGGTGCCGAAGTGCTCCGTTG
CCATGCCGTCATGGGGCGCATTGATCTGCGCGATCTCCTTGCCCGCCTCGGTGCCCGTGGGGTGCAATCGATCCTCCTCG
AAGGGGGGAGCGAACTGGCCGGCGAAGCACTCCGTGCCGGGCTCATCGACAAATGTGTCCTCTTCTACGCCCCCAAGTTT
TTGGGGGGAGCCGCCGGTCTGGGGCTCTTTGGCGGGCCGTCGGCCGAAAGAATGGATGGATGCTGCCGGCTGAAGGATGT
AAGCGTGCGGCGTTTCGGCGATGACGTGATGATCGAGGCTTATCCGGAGGATTTATGTTTACCGGGCTCATAG

Upstream 100 bases:

>100_bases
CGACGAGGTGGCCTATGTCCGTTTTGCCTCCGTCTACCGCTCCTTCAAGGACGTGAACGAGTTCATGGCCGAACTGCAGG
ACCTCCTGAAGAAGTAACCC

Downstream 100 bases:

>100_bases
AAGACGTAGGATCGGTAAGAAGGCTTGAACGGGCAGGGGGGGCGGCACGGCTCACCACCGCCACAAAAATTCCGCTGGAT
TCCATTGCCCTCGGTGACTC

Product: 5-amino-6-(5-phosphoribosylamino)uracil reductase/diaminohydroxyphosphoribosylaminopyrimidine deaminase

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 370; Mature: 370

Protein sequence:

>370_residues
MDVSPEKIMKRALALARRGKGKTSPNPAVGCVIVRDGAIVGEGWHRKAGTPHAEVHALRQAGELARGADVYVTLEPCSHF
GKTPPCADALVEAGVGRVFVGMVDPNPKVSGRGIERLRVAGIEVVTGIREAECRRLNEPFVKHVTTGLPFVILKSAMTMD
GKTATASGDSRWITNEKSRRYVHKLRSMVDAIMVGVGTVLADDPQLTARIPRGKDPVRVVVDSSLRIPSGARMLHQESPA
TTVVATVSEDRNRIVKLESAGAEVLRCHAVMGRIDLRDLLARLGARGVQSILLEGGSELAGEALRAGLIDKCVLFYAPKF
LGGAAGLGLFGGPSAERMDGCCRLKDVSVRRFGDDVMIEAYPEDLCLPGS

Sequences:

>Translated_370_residues
MDVSPEKIMKRALALARRGKGKTSPNPAVGCVIVRDGAIVGEGWHRKAGTPHAEVHALRQAGELARGADVYVTLEPCSHF
GKTPPCADALVEAGVGRVFVGMVDPNPKVSGRGIERLRVAGIEVVTGIREAECRRLNEPFVKHVTTGLPFVILKSAMTMD
GKTATASGDSRWITNEKSRRYVHKLRSMVDAIMVGVGTVLADDPQLTARIPRGKDPVRVVVDSSLRIPSGARMLHQESPA
TTVVATVSEDRNRIVKLESAGAEVLRCHAVMGRIDLRDLLARLGARGVQSILLEGGSELAGEALRAGLIDKCVLFYAPKF
LGGAAGLGLFGGPSAERMDGCCRLKDVSVRRFGDDVMIEAYPEDLCLPGS
>Mature_370_residues
MDVSPEKIMKRALALARRGKGKTSPNPAVGCVIVRDGAIVGEGWHRKAGTPHAEVHALRQAGELARGADVYVTLEPCSHF
GKTPPCADALVEAGVGRVFVGMVDPNPKVSGRGIERLRVAGIEVVTGIREAECRRLNEPFVKHVTTGLPFVILKSAMTMD
GKTATASGDSRWITNEKSRRYVHKLRSMVDAIMVGVGTVLADDPQLTARIPRGKDPVRVVVDSSLRIPSGARMLHQESPA
TTVVATVSEDRNRIVKLESAGAEVLRCHAVMGRIDLRDLLARLGARGVQSILLEGGSELAGEALRAGLIDKCVLFYAPKF
LGGAAGLGLFGGPSAERMDGCCRLKDVSVRRFGDDVMIEAYPEDLCLPGS

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG0117

COG function: function code H; Pyrimidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=367, Percent_Identity=46.0490463215259, Blast_Score=308, Evalue=5e-85,
Organism=Escherichia coli, GI145693172, Length=155, Percent_Identity=34.1935483870968, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 39527; Mature: 39527

Theoretical pI: Translated: 9.17; Mature: 9.17

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVSPEKIMKRALALARRGKGKTSPNPAVGCVIVRDGAIVGEGWHRKAGTPHAEVHALRQ
CCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCEEECCCCCCCCCCCHHHHHHHHH
AGELARGADVYVTLEPCSHFGKTPPCADALVEAGVGRVFVGMVDPNPKVSGRGIERLRVA
HHHHCCCCEEEEEECCHHHCCCCCCHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHH
GIEVVTGIREAECRRLNEPFVKHVTTGLPFVILKSAMTMDGKTATASGDSRWITNEKSRR
HHHHHHCCHHHHHHHCCCHHHHHHHCCCCHHHHHHHHCCCCCEEECCCCCCCCCCHHHHH
YVHKLRSMVDAIMVGVGTVLADDPQLTARIPRGKDPVRVVVDSSLRIPSGARMLHQESPA
HHHHHHHHHHHHHHHHHHHEECCCCCEEECCCCCCCEEEEECCCCCCCCCHHHHHCCCCC
TTVVATVSEDRNRIVKLESAGAEVLRCHAVMGRIDLRDLLARLGARGVQSILLEGGSELA
EEEEEEECCCCCEEEEEECCCHHHHHHHHHHCCCCHHHHHHHHCHHHHHHHHHCCCHHHH
GEALRAGLIDKCVLFYAPKFLGGAAGLGLFGGPSAERMDGCCRLKDVSVRRFGDDVMIEA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCCEECCCHHHHCCCCEEEEE
YPEDLCLPGS
CCCCCCCCCC
>Mature Secondary Structure
MDVSPEKIMKRALALARRGKGKTSPNPAVGCVIVRDGAIVGEGWHRKAGTPHAEVHALRQ
CCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCEEECCCCCCCCCCCHHHHHHHHH
AGELARGADVYVTLEPCSHFGKTPPCADALVEAGVGRVFVGMVDPNPKVSGRGIERLRVA
HHHHCCCCEEEEEECCHHHCCCCCCHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHH
GIEVVTGIREAECRRLNEPFVKHVTTGLPFVILKSAMTMDGKTATASGDSRWITNEKSRR
HHHHHHCCHHHHHHHCCCHHHHHHHCCCCHHHHHHHHCCCCCEEECCCCCCCCCCHHHHH
YVHKLRSMVDAIMVGVGTVLADDPQLTARIPRGKDPVRVVVDSSLRIPSGARMLHQESPA
HHHHHHHHHHHHHHHHHHHEECCCCCEEECCCCCCCEEEEECCCCCCCCCHHHHHCCCCC
TTVVATVSEDRNRIVKLESAGAEVLRCHAVMGRIDLRDLLARLGARGVQSILLEGGSELA
EEEEEEECCCCCEEEEEECCCHHHHHHHHHHCCCCHHHHHHHHCHHHHHHHHHCCCHHHH
GEALRAGLIDKCVLFYAPKFLGGAAGLGLFGGPSAERMDGCCRLKDVSVRRFGDDVMIEA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCCEECCCHHHHCCCCEEEEE
YPEDLCLPGS
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8522537 [H]