Click here to switch to the map view.

The map label for this gene is nrdR

Identifier: 78222832

GI number: 78222832

Start: 1821039

End: 1821491

Strand: Direct

Name: nrdR

Synonym: Gmet_1623

Alternate gene names: 78222832

Gene position: 1821039-1821491 (Clockwise)

Preceding gene: 78222831

Following gene: 78222833

Centisome position: 45.56

GC content: 61.37

Gene sequence:

>453_bases
GTGAAATGCCCCTTTTGCGCCCATCCTGACAGCAAGGTCGTTGACTCCCGCCCCGACAAGGGTGGGGCTGCTATCCGGCG
TCGCCGCGAGTGCGAATCCTGCGCCAAGCGCTTTACGACCCATGAGCGGATTGAGGAGACTCTTCCCCTGGTTCTCAAGA
AGGACGGCCGCCGGGAGCCCTTCGACCGGATGAAGATCGTGGGCGGCATCCTGAAGGCGTGTGAGAAGCGCCAGGTGTCG
CGGGAGACCGTCGACCGTCTCGTGGACCGGCTCGAAGGACGGCTCCAGGAGTGGAGCGAGAAGGAAGTACCCAGTACCAC
CATCGGCGAGTGGGTCATGACCGAACTCCATGACATCGACGAGGTGGCCTATGTCCGTTTTGCCTCCGTCTACCGCTCCT
TCAAGGACGTGAACGAGTTCATGGCCGAACTGCAGGACCTCCTGAAGAAGTAA

Upstream 100 bases:

>100_bases
TTGTCTACGAAGAGGGCTACTCGGACGAACTGGCCCGGGAGATGATCGGCGAATCGGGGGTCGTGGTGGAAAAATTTGGT
GATATAAGGGGGGAAACCCC

Downstream 100 bases:

>100_bases
CCCATGGATGTGTCTCCCGAAAAGATCATGAAGCGTGCTCTGGCGCTGGCAAGGCGGGGCAAGGGCAAAACGTCTCCGAA
TCCGGCGGTGGGGTGCGTCA

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 150; Mature: 150

Protein sequence:

>150_residues
MKCPFCAHPDSKVVDSRPDKGGAAIRRRRECESCAKRFTTHERIEETLPLVLKKDGRREPFDRMKIVGGILKACEKRQVS
RETVDRLVDRLEGRLQEWSEKEVPSTTIGEWVMTELHDIDEVAYVRFASVYRSFKDVNEFMAELQDLLKK

Sequences:

>Translated_150_residues
MKCPFCAHPDSKVVDSRPDKGGAAIRRRRECESCAKRFTTHERIEETLPLVLKKDGRREPFDRMKIVGGILKACEKRQVS
RETVDRLVDRLEGRLQEWSEKEVPSTTIGEWVMTELHDIDEVAYVRFASVYRSFKDVNEFMAELQDLLKK
>Mature_150_residues
MKCPFCAHPDSKVVDSRPDKGGAAIRRRRECESCAKRFTTHERIEETLPLVLKKDGRREPFDRMKIVGGILKACEKRQVS
RETVDRLVDRLEGRLQEWSEKEVPSTTIGEWVMTELHDIDEVAYVRFASVYRSFKDVNEFMAELQDLLKK

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=147, Percent_Identity=47.6190476190476, Blast_Score=143, Evalue=5e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR_GEOMG (Q39V70)

Other databases:

- EMBL:   CP000148
- RefSeq:   YP_384579.1
- STRING:   Q39V70
- GeneID:   3739362
- GenomeReviews:   CP000148_GR
- KEGG:   gme:Gmet_1623
- NMPDR:   fig|269799.3.peg.1075
- eggNOG:   COG1327
- HOGENOM:   HBG351755
- OMA:   FASVYRD
- PhylomeDB:   Q39V70
- ProtClustDB:   PRK00464
- BioCyc:   GMET269799:GMET_1623-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 17500; Mature: 17500

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKCPFCAHPDSKVVDSRPDKGGAAIRRRRECESCAKRFTTHERIEETLPLVLKKDGRREP
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
FDRMKIVGGILKACEKRQVSRETVDRLVDRLEGRLQEWSEKEVPSTTIGEWVMTELHDID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
EVAYVRFASVYRSFKDVNEFMAELQDLLKK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKCPFCAHPDSKVVDSRPDKGGAAIRRRRECESCAKRFTTHERIEETLPLVLKKDGRREP
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
FDRMKIVGGILKACEKRQVSRETVDRLVDRLEGRLQEWSEKEVPSTTIGEWVMTELHDID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
EVAYVRFASVYRSFKDVNEFMAELQDLLKK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA