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The map label for this gene is etfA [H]

Identifier: 78222738

GI number: 78222738

Start: 1728687

End: 1729574

Strand: Direct

Name: etfA [H]

Synonym: Gmet_1526

Alternate gene names: 78222738

Gene position: 1728687-1729574 (Clockwise)

Preceding gene: 78222737

Following gene: 78222739

Centisome position: 43.25

GC content: 62.05

Gene sequence:

>888_bases
ATGAAAACGCTGATCATCGAAACGGCCAATGCCAAGATCCTTGGGGAACTGGTAACCGTAAGCAGGCTGTTCGGCCAGGC
CCCGGATGTTGTCGTGCTGGGCAGCGGGGAGTTGCAGGGGAGCTACGGCAAGGCCTACCGGCTTTCCGATACCCTTGGGG
CGAACCTCGGCTCCTCCCTCTCCGACCTGATCAAGAGGGAAAGGTACGAGCTGATTCTTCTCAGCACGACTGCCATCGGC
AGCGGCTTGGCCGGCCCCCTGGCGGTGAGCCTCGGCGCGCCGATTCTGTCCGAGGTTACCGCCATAAGTCCTGACCTGAC
AATCGAGCGGTCCCTCTACGGCTCCAAGGCTGTTGCCCGTTACAAGCTGGAGTCCGGGCCGCTGGTTCTGACAATCAAGC
GTAAATACTTCGAAGCGGCCACGTTGGAAGGAACGACGGCAACCGAAGAATTACCGGTCGGACCGCAGAAAATAACACTT
CTGGAAGAGATCGAGGAGGAGCGCACCGGTATTCCGCTGGAGGACGCCGAGGTCGTGGTGACCGGCGGGCGGGGGATCGG
CAGCGGCGACAACTTCTCCATCCTGAAGGAGATAGCCGGAATGCTGAACGGCGCGGTAGGGGCGTCCCGGGGGGCGGTGG
ACGAGGGGTGGATGCCGCCCGGCGCCCAGATCGGCCAGACCGGCAAAATCGTCGCGCCCACCGTCTATTTCGCGGTCGGG
GTGTCCGGCGCCAGCCAGCATCTGGCGGGGATTTCCAACGCCAAATGCGTCATAGCCATCAACAAGGACAACGAGGCGAA
CATCTTCAAACGGGCCAGGTTCGGCATCGTCGGTGACTACAAAAAGGCGGTCCCGGCCCTGATCAACGCCCTCAAGGAGA
ACGCCTGA

Upstream 100 bases:

>100_bases
GCATCCCCAAGGTCGAGTCCAACTGTGAACTTATACCGGCCGAGGATATGGACGATGCTGTTCGTGTTCTCTTGAGAAGG
CTCAAGGAGGAACGGTACCT

Downstream 100 bases:

>100_bases
CATGGAACGGATCCCCTACTGGAATATCAGCTATGGCCTCCTGATCGACCTCCTCTCCATCCCGGCAATGGCCGTGTTCG
GGTACGGGATCTACCGCCAC

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MKTLIIETANAKILGELVTVSRLFGQAPDVVVLGSGELQGSYGKAYRLSDTLGANLGSSLSDLIKRERYELILLSTTAIG
SGLAGPLAVSLGAPILSEVTAISPDLTIERSLYGSKAVARYKLESGPLVLTIKRKYFEAATLEGTTATEELPVGPQKITL
LEEIEEERTGIPLEDAEVVVTGGRGIGSGDNFSILKEIAGMLNGAVGASRGAVDEGWMPPGAQIGQTGKIVAPTVYFAVG
VSGASQHLAGISNAKCVIAINKDNEANIFKRARFGIVGDYKKAVPALINALKENA

Sequences:

>Translated_295_residues
MKTLIIETANAKILGELVTVSRLFGQAPDVVVLGSGELQGSYGKAYRLSDTLGANLGSSLSDLIKRERYELILLSTTAIG
SGLAGPLAVSLGAPILSEVTAISPDLTIERSLYGSKAVARYKLESGPLVLTIKRKYFEAATLEGTTATEELPVGPQKITL
LEEIEEERTGIPLEDAEVVVTGGRGIGSGDNFSILKEIAGMLNGAVGASRGAVDEGWMPPGAQIGQTGKIVAPTVYFAVG
VSGASQHLAGISNAKCVIAINKDNEANIFKRARFGIVGDYKKAVPALINALKENA
>Mature_295_residues
MKTLIIETANAKILGELVTVSRLFGQAPDVVVLGSGELQGSYGKAYRLSDTLGANLGSSLSDLIKRERYELILLSTTAIG
SGLAGPLAVSLGAPILSEVTAISPDLTIERSLYGSKAVARYKLESGPLVLTIKRKYFEAATLEGTTATEELPVGPQKITL
LEEIEEERTGIPLEDAEVVVTGGRGIGSGDNFSILKEIAGMLNGAVGASRGAVDEGWMPPGAQIGQTGKIVAPTVYFAVG
VSGASQHLAGISNAKCVIAINKDNEANIFKRARFGIVGDYKKAVPALINALKENA

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=234, Percent_Identity=41.4529914529915, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI189181759, Length=234, Percent_Identity=41.4529914529915, Blast_Score=166, Evalue=2e-41,
Organism=Escherichia coli, GI1787990, Length=307, Percent_Identity=31.5960912052117, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1786226, Length=270, Percent_Identity=30.7407407407407, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI87082157, Length=249, Percent_Identity=29.3172690763052, Blast_Score=94, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17506929, Length=230, Percent_Identity=41.7391304347826, Blast_Score=161, Evalue=3e-40,
Organism=Saccharomyces cerevisiae, GI6325261, Length=254, Percent_Identity=33.0708661417323, Blast_Score=130, Evalue=2e-31,
Organism=Drosophila melanogaster, GI17136898, Length=228, Percent_Identity=43.421052631579, Blast_Score=168, Evalue=5e-42,
Organism=Drosophila melanogaster, GI24652801, Length=228, Percent_Identity=43.421052631579, Blast_Score=168, Evalue=5e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 30783; Mature: 30783

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLIIETANAKILGELVTVSRLFGQAPDVVVLGSGELQGSYGKAYRLSDTLGANLGSSL
CCEEEEEECCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCEEEECHHHCCCCCHHH
SDLIKRERYELILLSTTAIGSGLAGPLAVSLGAPILSEVTAISPDLTIERSLYGSKAVAR
HHHHHHCCEEEEEEEECCCCCCCCCHHHHHHCCHHHHHHHHCCCCCEEEHHHCCCCCEEE
YKLESGPLVLTIKRKYFEAATLEGTTATEELPVGPQKITLLEEIEEERTGIPLEDAEVVV
EEECCCCEEEEEEHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEE
TGGRGIGSGDNFSILKEIAGMLNGAVGASRGAVDEGWMPPGAQIGQTGKIVAPTVYFAVG
ECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEECCEEEEEEE
VSGASQHLAGISNAKCVIAINKDNEANIFKRARFGIVGDYKKAVPALINALKENA
CCCCHHHHCCCCCCEEEEEECCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKTLIIETANAKILGELVTVSRLFGQAPDVVVLGSGELQGSYGKAYRLSDTLGANLGSSL
CCEEEEEECCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCEEEECHHHCCCCCHHH
SDLIKRERYELILLSTTAIGSGLAGPLAVSLGAPILSEVTAISPDLTIERSLYGSKAVAR
HHHHHHCCEEEEEEEECCCCCCCCCHHHHHHCCHHHHHHHHCCCCCEEEHHHCCCCCEEE
YKLESGPLVLTIKRKYFEAATLEGTTATEELPVGPQKITLLEEIEEERTGIPLEDAEVVV
EEECCCCEEEEEEHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEE
TGGRGIGSGDNFSILKEIAGMLNGAVGASRGAVDEGWMPPGAQIGQTGKIVAPTVYFAVG
ECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEECCEEEEEEE
VSGASQHLAGISNAKCVIAINKDNEANIFKRARFGIVGDYKKAVPALINALKENA
CCCCHHHHCCCCCCEEEEEECCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]