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The map label for this gene is frc [H]

Identifier: 78222734

GI number: 78222734

Start: 1724614

End: 1725843

Strand: Direct

Name: frc [H]

Synonym: Gmet_1522

Alternate gene names: 78222734

Gene position: 1724614-1725843 (Clockwise)

Preceding gene: 78222733

Following gene: 78222735

Centisome position: 43.14

GC content: 60.16

Gene sequence:

>1230_bases
ATGTTGCCAAATCTTAAAAAGGCCCTTGATGGGATCGTGGTGTGCGACTTTTCCTGGGTGGGGGCCGGTCCGATTGCCAC
GAACGTCCTCGGCCAGTGCGGTGCCGAGGTTATCAAGATTGAAAGCAAAAGCCGGCCGGACTTACTTCGGACCGGCGGCC
CGTTCAAGGACGGGATCAATGAGGGGCTGGAACGGAGCGGCTATTTTGCCAACCGCAATCCCAACAAGAAAGGGATCGCG
CTGGACATGAGCCATCCCAAGGCACGGGCCGTTGCGGTTCGCCTGATCAGGAAAAGCGACATCGTCATCAATAACTTCCG
TGTTGGGCAGATGGAGAAGTGGGGGCTCGGGTGGGAGGACGTCCGGAAGATTAATCCGCGGATCATCTACGTCACCATGA
GCCTGCAGGGGGAAACCGGACCGCAGAAGAGCTACATGGGGTTCGGGGTCAATCTTAACGCCCTGTGTGGTCTGACGGCC
CAGGCATGTTTTCCCGGCGAGCGCCCCTTCGGCACCGGCACGAATTATACCGACCACGTCATGGCCCCGAGCCATACCCT
CTTTGGCATCATGGCAGCCTTACTTGAACGGGAGCAGACCGGAGAAGGGCAGACCGTGGCCATCTCCCAGCTGAAATCCG
CCATCAGCATGGCTCCGACGAGTGCCATGACCTATGCGGCAAACGGCGACACGCTGGGGCCGGCGGGACTTAGTGATCCG
AATGCTGCGCCCCACGGCCTGTTCACGACACTCGGCTACCGGAGATGGATTGCCATTGCCGTGTTCAGCGAGGACGAATG
GCGGGCGCTCAAGAAGGTTATGGGCAACCCCGCTTGGGCCGAGGATGGGAAGTTCGGCTCGTTGCAAAGTCGTAAGGAAA
ACGAGGCGGAGTTGAATGAGCATATGGAGGCGTGGACCAGCCGGCAGCACGCGGACAAGATCATGGACGAGCTGCTGCGC
AACGGCGTCAGAGCGGGCGTGGTCAACGATGCCCGGGGCGCCATCGAGGATGATCACTTGAGGGAGCGGGAGTTCTGGTC
GTACCTGGACCATCCGGTAATGGGGCGCACCCTCTACAACCGGGCGCCGATCCGCCTTTCCAAAACCCCGCTCCGGATGG
AAACCGCGGCCCCGTTGCTGGGTCAGCACACCAGGGATGTGCTGAAGGGGATGCTGGACTATACGGATGAAGAAATCGCG
ATGCTCAGCGAGGAAAAGGTGCTTGTGTAG

Upstream 100 bases:

>100_bases
GATTTTGCTCCCACCTTTGGCCAGCATACCGCCGAGGTGCTGGGCGAATGCGGCTATAGCCGCAGTGAAATCGATGCGCT
TGACAGGGAGGGAGTTGTTC

Downstream 100 bases:

>100_bases
CTGCCTTTCAATACTACCACCAGGAGAAAGAGAATGGATTTCAGCATACCCGAAGAATACATGATGCTCAAAGAGTCGAT
GCGCGAGTTCGTCAAGCGCG

Product: L-carnitine dehydratase/bile acid-inducible protein F

Products: NA

Alternate protein names: Formyl-CoA transferase [H]

Number of amino acids: Translated: 409; Mature: 409

Protein sequence:

>409_residues
MLPNLKKALDGIVVCDFSWVGAGPIATNVLGQCGAEVIKIESKSRPDLLRTGGPFKDGINEGLERSGYFANRNPNKKGIA
LDMSHPKARAVAVRLIRKSDIVINNFRVGQMEKWGLGWEDVRKINPRIIYVTMSLQGETGPQKSYMGFGVNLNALCGLTA
QACFPGERPFGTGTNYTDHVMAPSHTLFGIMAALLEREQTGEGQTVAISQLKSAISMAPTSAMTYAANGDTLGPAGLSDP
NAAPHGLFTTLGYRRWIAIAVFSEDEWRALKKVMGNPAWAEDGKFGSLQSRKENEAELNEHMEAWTSRQHADKIMDELLR
NGVRAGVVNDARGAIEDDHLREREFWSYLDHPVMGRTLYNRAPIRLSKTPLRMETAAPLLGQHTRDVLKGMLDYTDEEIA
MLSEEKVLV

Sequences:

>Translated_409_residues
MLPNLKKALDGIVVCDFSWVGAGPIATNVLGQCGAEVIKIESKSRPDLLRTGGPFKDGINEGLERSGYFANRNPNKKGIA
LDMSHPKARAVAVRLIRKSDIVINNFRVGQMEKWGLGWEDVRKINPRIIYVTMSLQGETGPQKSYMGFGVNLNALCGLTA
QACFPGERPFGTGTNYTDHVMAPSHTLFGIMAALLEREQTGEGQTVAISQLKSAISMAPTSAMTYAANGDTLGPAGLSDP
NAAPHGLFTTLGYRRWIAIAVFSEDEWRALKKVMGNPAWAEDGKFGSLQSRKENEAELNEHMEAWTSRQHADKIMDELLR
NGVRAGVVNDARGAIEDDHLREREFWSYLDHPVMGRTLYNRAPIRLSKTPLRMETAAPLLGQHTRDVLKGMLDYTDEEIA
MLSEEKVLV
>Mature_409_residues
MLPNLKKALDGIVVCDFSWVGAGPIATNVLGQCGAEVIKIESKSRPDLLRTGGPFKDGINEGLERSGYFANRNPNKKGIA
LDMSHPKARAVAVRLIRKSDIVINNFRVGQMEKWGLGWEDVRKINPRIIYVTMSLQGETGPQKSYMGFGVNLNALCGLTA
QACFPGERPFGTGTNYTDHVMAPSHTLFGIMAALLEREQTGEGQTVAISQLKSAISMAPTSAMTYAANGDTLGPAGLSDP
NAAPHGLFTTLGYRRWIAIAVFSEDEWRALKKVMGNPAWAEDGKFGSLQSRKENEAELNEHMEAWTSRQHADKIMDELLR
NGVRAGVVNDARGAIEDDHLREREFWSYLDHPVMGRTLYNRAPIRLSKTPLRMETAAPLLGQHTRDVLKGMLDYTDEEIA
MLSEEKVLV

Specific function: Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate [H]

COG id: COG1804

COG function: function code C; Predicted acyl-CoA transferases/carnitine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CaiB/BaiF CoA-transferase family [H]

Homologues:

Organism=Homo sapiens, GI300863128, Length=403, Percent_Identity=27.7915632754342, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI300863124, Length=429, Percent_Identity=26.8065268065268, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI300863126, Length=396, Percent_Identity=24.7474747474747, Blast_Score=125, Evalue=6e-29,
Organism=Homo sapiens, GI266456254, Length=423, Percent_Identity=25.531914893617, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI42794625, Length=423, Percent_Identity=25.531914893617, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI13376042, Length=429, Percent_Identity=24.2424242424242, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI266458397, Length=200, Percent_Identity=31.5, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI266458393, Length=200, Percent_Identity=31.5, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI266458395, Length=151, Percent_Identity=33.112582781457, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI42822893, Length=151, Percent_Identity=33.112582781457, Blast_Score=76, Evalue=6e-14,
Organism=Escherichia coli, GI87082093, Length=318, Percent_Identity=29.559748427673, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1788717, Length=430, Percent_Identity=26.9767441860465, Blast_Score=119, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24648431, Length=408, Percent_Identity=29.4117647058824, Blast_Score=152, Evalue=5e-37,
Organism=Drosophila melanogaster, GI24585488, Length=210, Percent_Identity=29.5238095238095, Blast_Score=86, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003673
- InterPro:   IPR017659 [H]

Pfam domain/function: PF02515 CoA_transf_3 [H]

EC number: =2.8.3.16 [H]

Molecular weight: Translated: 45070; Mature: 45070

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPNLKKALDGIVVCDFSWVGAGPIATNVLGQCGAEVIKIESKSRPDLLRTGGPFKDGIN
CCCCHHHHHCCEEEEECCCCCCCHHHHHHHHHCCCEEEEECCCCCCCHHHCCCCCHHHHH
EGLERSGYFANRNPNKKGIALDMSHPKARAVAVRLIRKSDIVINNFRVGQMEKWGLGWED
HHHHHCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHCCEEEECEECCCCHHCCCCHHH
VRKINPRIIYVTMSLQGETGPQKSYMGFGVNLNALCGLTAQACFPGERPFGTGTNYTDHV
HHHCCCEEEEEEEEECCCCCCCCCCEECCCCHHHHHCCHHHHCCCCCCCCCCCCCCCCCC
MAPSHTLFGIMAALLEREQTGEGQTVAISQLKSAISMAPTSAMTYAANGDTLGPAGLSDP
CCCCHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHCCCHHEEEECCCCCCCCCCCCCC
NAAPHGLFTTLGYRRWIAIAVFSEDEWRALKKVMGNPAWAEDGKFGSLQSRKENEAELNE
CCCCCHHHHHHHHEEEEEEEEECCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHH
HMEAWTSRQHADKIMDELLRNGVRAGVVNDARGAIEDDHLREREFWSYLDHPVMGRTLYN
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHCHHHHC
RAPIRLSKTPLRMETAAPLLGQHTRDVLKGMLDYTDEEIAMLSEEKVLV
CCCCEECCCCCCHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCC
>Mature Secondary Structure
MLPNLKKALDGIVVCDFSWVGAGPIATNVLGQCGAEVIKIESKSRPDLLRTGGPFKDGIN
CCCCHHHHHCCEEEEECCCCCCCHHHHHHHHHCCCEEEEECCCCCCCHHHCCCCCHHHHH
EGLERSGYFANRNPNKKGIALDMSHPKARAVAVRLIRKSDIVINNFRVGQMEKWGLGWED
HHHHHCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHCCEEEECEECCCCHHCCCCHHH
VRKINPRIIYVTMSLQGETGPQKSYMGFGVNLNALCGLTAQACFPGERPFGTGTNYTDHV
HHHCCCEEEEEEEEECCCCCCCCCCEECCCCHHHHHCCHHHHCCCCCCCCCCCCCCCCCC
MAPSHTLFGIMAALLEREQTGEGQTVAISQLKSAISMAPTSAMTYAANGDTLGPAGLSDP
CCCCHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHCCCHHEEEECCCCCCCCCCCCCC
NAAPHGLFTTLGYRRWIAIAVFSEDEWRALKKVMGNPAWAEDGKFGSLQSRKENEAELNE
CCCCCHHHHHHHHEEEEEEEEECCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHH
HMEAWTSRQHADKIMDELLRNGVRAGVVNDARGAIEDDHLREREFWSYLDHPVMGRTLYN
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHCHHHHC
RAPIRLSKTPLRMETAAPLLGQHTRDVLKGMLDYTDEEIAMLSEEKVLV
CCCCEECCCCCCHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]