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The map label for this gene is frc [H]

Identifier: 78222733

GI number: 78222733

Start: 1723392

End: 1724630

Strand: Direct

Name: frc [H]

Synonym: Gmet_1521

Alternate gene names: 78222733

Gene position: 1723392-1724630 (Clockwise)

Preceding gene: 78222725

Following gene: 78222734

Centisome position: 43.11

GC content: 52.06

Gene sequence:

>1239_bases
ATGAGTAATACCGGATCGTTATCATATCTGCGGATATTGGATTTTACTGGTGAGATTGGACCTTATGCAGCAAAACTATA
TGCAGGCCTAGGCGCTGACGTTATTCACATAGAGCCAATTGCAGGAGATACATTACGTTCAACAGGTCCGTTCTTTGGGA
ACCGTCCCGGCAAAGAAAGAAGTATGCAATTCATTTATTACAATGCAGGCAAAAGAGGGTTGGTGTTGGATCTGAAAAAA
GAAAAAGGAAAAGAAGTTTTTGTCGACCTGTGTAAGGGCGCTGACATTTTGTTTGAGAGTTTTACACCCGGTTATCTTGA
TGAACTTGGCCTTTCTTTTGATGTGTTGAGTGCGGCAAACCCCAAATTGGTACAAACATCCATTACACCATTCGGTAGCT
TCGGACCATACAGTACGTATCCCGGTTCCGACCTGACTTGTTCTGCCCTCGGCGGTTTTTTGTATCTGGCCGGTATCGAT
AACGACAAACCGGTAAGGGCTTGTGACAATCAGGCGTACCGGATGGCAGAGGTATACGCAGCAGTCGGGAGTTCGATCGC
ACTCTTGTTCGCTCAAAAAACCGGGGTGGGCCAATTTGTTGATGTCTCCTGCATGGAGGCAGTCGGCATGGCCTTGGAGA
CTGCCGCTCAATGCTGGGACCTCGAAGGGACGCTGAGAAGGGGGCGGGGCAAGGAGGCGGGTTCGGCCACGATCCATCCA
TGTAAGGACGGGTTTATCGCTATCGTCGCCATCGTAGGTAGAAACAAGACGATGTGGACACCTTTTGTCCAGTGGATGAA
GGAGGAAGGTGTTGAAGAATGGGAACTGTTCGACAACGACAACTGGATCAACGCGTCCTACCGGGAGTCCAAGGCTGGAT
ACGAACTGTTCTGCCGCATCTTCGAACGGTTTACCATGAAGCACACCAAGCAATACCTCTATGACGCCGGTCAGGCCCAC
CGGGTCGCCGTCAGCCCGGTCAGCAACGGCAAAGACCTTCTGGAAAACCCCCAGCTGAACCATCACGACTTCTGGCAGCG
GCTGTATCACGAACCGGTCGGCGCCGAGGTGGTCTGTCCGGGAGCTCCCTACGAGTTCGGGCACCTCAAGTGGCGCCTGG
GTGATTTTGCTCCCACCTTTGGCCAGCATACCGCCGAGGTGCTGGGCGAATGCGGCTATAGCCGCAGTGAAATCGATGCG
CTTGACAGGGAGGGAGTTGTTCATGTTGCCAAATCTTAA

Upstream 100 bases:

>100_bases
GTGAAAACTACCTTCTCTTACATTCTAGTTTAGGTTTTTGTGAGAGAAACGGTAAGTAACTGGCATTACATTAACCATGC
AGCTGACTGGAGATAATCAA

Downstream 100 bases:

>100_bases
AAAGGCCCTTGATGGGATCGTGGTGTGCGACTTTTCCTGGGTGGGGGCCGGTCCGATTGCCACGAACGTCCTCGGCCAGT
GCGGTGCCGAGGTTATCAAG

Product: L-carnitine dehydratase/bile acid-inducible protein F

Products: NA

Alternate protein names: Formyl-CoA transferase [H]

Number of amino acids: Translated: 412; Mature: 411

Protein sequence:

>412_residues
MSNTGSLSYLRILDFTGEIGPYAAKLYAGLGADVIHIEPIAGDTLRSTGPFFGNRPGKERSMQFIYYNAGKRGLVLDLKK
EKGKEVFVDLCKGADILFESFTPGYLDELGLSFDVLSAANPKLVQTSITPFGSFGPYSTYPGSDLTCSALGGFLYLAGID
NDKPVRACDNQAYRMAEVYAAVGSSIALLFAQKTGVGQFVDVSCMEAVGMALETAAQCWDLEGTLRRGRGKEAGSATIHP
CKDGFIAIVAIVGRNKTMWTPFVQWMKEEGVEEWELFDNDNWINASYRESKAGYELFCRIFERFTMKHTKQYLYDAGQAH
RVAVSPVSNGKDLLENPQLNHHDFWQRLYHEPVGAEVVCPGAPYEFGHLKWRLGDFAPTFGQHTAEVLGECGYSRSEIDA
LDREGVVHVAKS

Sequences:

>Translated_412_residues
MSNTGSLSYLRILDFTGEIGPYAAKLYAGLGADVIHIEPIAGDTLRSTGPFFGNRPGKERSMQFIYYNAGKRGLVLDLKK
EKGKEVFVDLCKGADILFESFTPGYLDELGLSFDVLSAANPKLVQTSITPFGSFGPYSTYPGSDLTCSALGGFLYLAGID
NDKPVRACDNQAYRMAEVYAAVGSSIALLFAQKTGVGQFVDVSCMEAVGMALETAAQCWDLEGTLRRGRGKEAGSATIHP
CKDGFIAIVAIVGRNKTMWTPFVQWMKEEGVEEWELFDNDNWINASYRESKAGYELFCRIFERFTMKHTKQYLYDAGQAH
RVAVSPVSNGKDLLENPQLNHHDFWQRLYHEPVGAEVVCPGAPYEFGHLKWRLGDFAPTFGQHTAEVLGECGYSRSEIDA
LDREGVVHVAKS
>Mature_411_residues
SNTGSLSYLRILDFTGEIGPYAAKLYAGLGADVIHIEPIAGDTLRSTGPFFGNRPGKERSMQFIYYNAGKRGLVLDLKKE
KGKEVFVDLCKGADILFESFTPGYLDELGLSFDVLSAANPKLVQTSITPFGSFGPYSTYPGSDLTCSALGGFLYLAGIDN
DKPVRACDNQAYRMAEVYAAVGSSIALLFAQKTGVGQFVDVSCMEAVGMALETAAQCWDLEGTLRRGRGKEAGSATIHPC
KDGFIAIVAIVGRNKTMWTPFVQWMKEEGVEEWELFDNDNWINASYRESKAGYELFCRIFERFTMKHTKQYLYDAGQAHR
VAVSPVSNGKDLLENPQLNHHDFWQRLYHEPVGAEVVCPGAPYEFGHLKWRLGDFAPTFGQHTAEVLGECGYSRSEIDAL
DREGVVHVAKS

Specific function: Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate [H]

COG id: COG1804

COG function: function code C; Predicted acyl-CoA transferases/carnitine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CaiB/BaiF CoA-transferase family [H]

Homologues:

Organism=Homo sapiens, GI300863128, Length=413, Percent_Identity=28.8135593220339, Blast_Score=143, Evalue=2e-34,
Organism=Homo sapiens, GI300863124, Length=438, Percent_Identity=27.6255707762557, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI300863126, Length=413, Percent_Identity=27.6029055690073, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI266456254, Length=428, Percent_Identity=24.5327102803738, Blast_Score=96, Evalue=9e-20,
Organism=Homo sapiens, GI42794625, Length=427, Percent_Identity=24.5901639344262, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI13376042, Length=438, Percent_Identity=25.7990867579909, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI266458393, Length=203, Percent_Identity=29.064039408867, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI266458397, Length=203, Percent_Identity=29.064039408867, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI42822893, Length=133, Percent_Identity=32.3308270676692, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI266458395, Length=148, Percent_Identity=30.4054054054054, Blast_Score=75, Evalue=2e-13,
Organism=Escherichia coli, GI87082093, Length=211, Percent_Identity=33.175355450237, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1788717, Length=421, Percent_Identity=25.8907363420428, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1786222, Length=432, Percent_Identity=25.462962962963, Blast_Score=81, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24648431, Length=407, Percent_Identity=28.2555282555283, Blast_Score=128, Evalue=8e-30,
Organism=Drosophila melanogaster, GI24585488, Length=202, Percent_Identity=31.1881188118812, Blast_Score=94, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003673
- InterPro:   IPR017659 [H]

Pfam domain/function: PF02515 CoA_transf_3 [H]

EC number: =2.8.3.16 [H]

Molecular weight: Translated: 45452; Mature: 45321

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNTGSLSYLRILDFTGEIGPYAAKLYAGLGADVIHIEPIAGDTLRSTGPFFGNRPGKER
CCCCCCEEEEEEEECCCCCCHHHHHHHHCCCCCEEEEECCCCCCHHCCCCCCCCCCCCCC
SMQFIYYNAGKRGLVLDLKKEKGKEVFVDLCKGADILFESFTPGYLDELGLSFDVLSAAN
CEEEEEEECCCCCEEEEECCCCCHHHHHHHHCCCHHHHHCCCCCHHHHHCCCEEECCCCC
PKLVQTSITPFGSFGPYSTYPGSDLTCSALGGFLYLAGIDNDKPVRACDNQAYRMAEVYA
CCEEEEECCCCCCCCCCCCCCCCCCCHHHHCCEEEEEECCCCCCCHHHCCHHHHHHHHHH
AVGSSIALLFAQKTGVGQFVDVSCMEAVGMALETAAQCWDLEGTLRRGRGKEAGSATIHP
HHCCCEEEEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCC
CKDGFIAIVAIVGRNKTMWTPFVQWMKEEGVEEWELFDNDNWINASYRESKAGYELFCRI
CCCCEEEEEEEECCCCCCHHHHHHHHHHCCCCEEEEECCCCEECCCHHCCCCHHHHHHHH
FERFTMKHTKQYLYDAGQAHRVAVSPVSNGKDLLENPQLNHHDFWQRLYHEPVGAEVVCP
HHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHCCCCCCHHHHHHHHHCCCCCCEEECC
GAPYEFGHLKWRLGDFAPTFGQHTAEVLGECGYSRSEIDALDREGVVHVAKS
CCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCEEEEECC
>Mature Secondary Structure 
SNTGSLSYLRILDFTGEIGPYAAKLYAGLGADVIHIEPIAGDTLRSTGPFFGNRPGKER
CCCCCEEEEEEEECCCCCCHHHHHHHHCCCCCEEEEECCCCCCHHCCCCCCCCCCCCCC
SMQFIYYNAGKRGLVLDLKKEKGKEVFVDLCKGADILFESFTPGYLDELGLSFDVLSAAN
CEEEEEEECCCCCEEEEECCCCCHHHHHHHHCCCHHHHHCCCCCHHHHHCCCEEECCCCC
PKLVQTSITPFGSFGPYSTYPGSDLTCSALGGFLYLAGIDNDKPVRACDNQAYRMAEVYA
CCEEEEECCCCCCCCCCCCCCCCCCCHHHHCCEEEEEECCCCCCCHHHCCHHHHHHHHHH
AVGSSIALLFAQKTGVGQFVDVSCMEAVGMALETAAQCWDLEGTLRRGRGKEAGSATIHP
HHCCCEEEEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCC
CKDGFIAIVAIVGRNKTMWTPFVQWMKEEGVEEWELFDNDNWINASYRESKAGYELFCRI
CCCCEEEEEEEECCCCCCHHHHHHHHHHCCCCEEEEECCCCEECCCHHCCCCHHHHHHHH
FERFTMKHTKQYLYDAGQAHRVAVSPVSNGKDLLENPQLNHHDFWQRLYHEPVGAEVVCP
HHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHCCCCCCHHHHHHHHHCCCCCCEEECC
GAPYEFGHLKWRLGDFAPTFGQHTAEVLGECGYSRSEIDALDREGVVHVAKS
CCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]