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The map label for this gene is vanR [H]

Identifier: 78222725

GI number: 78222725

Start: 1713807

End: 1714547

Strand: Direct

Name: vanR [H]

Synonym: Gmet_1513

Alternate gene names: 78222725

Gene position: 1713807-1714547 (Clockwise)

Preceding gene: 78222718

Following gene: 78222733

Centisome position: 42.87

GC content: 53.04

Gene sequence:

>741_bases
ATGGAGTGGCTATCACGGAGGGAGGCGGTGAGGCTGCTGGAGCTGATAGATGCATCCAGAAGCTGTGCCGATATGGAAAG
GCTCAAACGGCTGTTCCATTCGCTCAACGATCTTCTATCTTTTGATATGGCCGTTTGTGGTACCGCACGCTTTGACGGAG
CCGGGACCATGAATGCCCAGCAGATCATCAACATATCTTACCCCGAGGAGTGGCTCAGTCTTTATGCTGAACATGATTTT
GCCGCGGTAGACCCAGTGGTACGCGCACATATAGCAGATTTCTCGGCTAAGCCTTGGAGCGAAGCATACCTCAAGTGGGG
ACGTCCGCAGCCATTTCTTTCCCTGGCGGAGGATTTCGGAATCCGCAAGGGTTATAGTTTCGGGGTCTTGTCATCAAACG
ACAGGACAGCAAGCATCTTCTCCCTTTGCGTCAGCGAGAAATACCCAGTGCATACCCCCCAAATACTCGACATCCTGGCC
CCGTATTTTCACGAGGCCCTGCGACGAACCGTGCAGACCGATCTGCCGTCCGCCTGTCTCGCCACCCTTACACCGCGTGA
AATCGAGGTGATTAGCTGGCTGGCCAACGGCAAGAACTACTGGGAAATATCGGTCATACTCGGAATCAGCGAACGGACCG
TAAAGTTCCATACTTCAACCATTGTGCAGAAGCTCGGAGCAGCAAACAGATCTCACGCTGTGGCTATAGCCATATCAACC
GGTTTGATATCTCTGGCTTGA

Upstream 100 bases:

>100_bases
GCATTTCGGTACGGCCAATCATTTGCCGGAATGATGCACTATATGTTAATGTCCCCTAAAAATCACCTGTCCATTGGGAC
AGTGACAATGAGGTATATAG

Downstream 100 bases:

>100_bases
TGTTGGGAGGGGAATACTCTTGCAGTGAAAAAGTTGTGTGCCGGTGTCACCATTGAGATTGCTCATGACTCCCTCCCAAA
TGTTCGGATGCACAGGCCAA

Product: LuxR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MEWLSRREAVRLLELIDASRSCADMERLKRLFHSLNDLLSFDMAVCGTARFDGAGTMNAQQIINISYPEEWLSLYAEHDF
AAVDPVVRAHIADFSAKPWSEAYLKWGRPQPFLSLAEDFGIRKGYSFGVLSSNDRTASIFSLCVSEKYPVHTPQILDILA
PYFHEALRRTVQTDLPSACLATLTPREIEVISWLANGKNYWEISVILGISERTVKFHTSTIVQKLGAANRSHAVAIAIST
GLISLA

Sequences:

>Translated_246_residues
MEWLSRREAVRLLELIDASRSCADMERLKRLFHSLNDLLSFDMAVCGTARFDGAGTMNAQQIINISYPEEWLSLYAEHDF
AAVDPVVRAHIADFSAKPWSEAYLKWGRPQPFLSLAEDFGIRKGYSFGVLSSNDRTASIFSLCVSEKYPVHTPQILDILA
PYFHEALRRTVQTDLPSACLATLTPREIEVISWLANGKNYWEISVILGISERTVKFHTSTIVQKLGAANRSHAVAIAIST
GLISLA
>Mature_246_residues
MEWLSRREAVRLLELIDASRSCADMERLKRLFHSLNDLLSFDMAVCGTARFDGAGTMNAQQIINISYPEEWLSLYAEHDF
AAVDPVVRAHIADFSAKPWSEAYLKWGRPQPFLSLAEDFGIRKGYSFGVLSSNDRTASIFSLCVSEKYPVHTPQILDILA
PYFHEALRRTVQTDLPSACLATLTPREIEVISWLANGKNYWEISVILGISERTVKFHTSTIVQKLGAANRSHAVAIAIST
GLISLA

Specific function: Probable transcriptional activator. Binds to autoinducer molecule ODHL [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH luxR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788224, Length=187, Percent_Identity=29.4117647058824, Blast_Score=85, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016032
- InterPro:   IPR005143
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF03472 Autoind_bind; PF00196 GerE [H]

EC number: NA

Molecular weight: Translated: 27505; Mature: 27505

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEWLSRREAVRLLELIDASRSCADMERLKRLFHSLNDLLSFDMAVCGTARFDGAGTMNAQ
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
QIINISYPEEWLSLYAEHDFAAVDPVVRAHIADFSAKPWSEAYLKWGRPQPFLSLAEDFG
HEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCHHHHHHHHCC
IRKGYSFGVLSSNDRTASIFSLCVSEKYPVHTPQILDILAPYFHEALRRTVQTDLPSACL
CCCCCCEEEECCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHH
ATLTPREIEVISWLANGKNYWEISVILGISERTVKFHTSTIVQKLGAANRSHAVAIAIST
HHCCCCHHHHHHHHHCCCCEEEEEEEEECCCHHEEHHHHHHHHHHCCCCCCCEEEEEEEC
GLISLA
CCCCCC
>Mature Secondary Structure
MEWLSRREAVRLLELIDASRSCADMERLKRLFHSLNDLLSFDMAVCGTARFDGAGTMNAQ
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
QIINISYPEEWLSLYAEHDFAAVDPVVRAHIADFSAKPWSEAYLKWGRPQPFLSLAEDFG
HEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCHHHHHHHHCC
IRKGYSFGVLSSNDRTASIFSLCVSEKYPVHTPQILDILAPYFHEALRRTVQTDLPSACL
CCCCCCEEEECCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHH
ATLTPREIEVISWLANGKNYWEISVILGISERTVKFHTSTIVQKLGAANRSHAVAIAIST
HHCCCCHHHHHHHHHCCCCEEEEEEEEECCCHHEEHHHHHHHHHHCCCCCCCEEEEEEEC
GLISLA
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9139920 [H]