Click here to switch to the map view.

The map label for this gene is ccrA [H]

Identifier: 78222724

GI number: 78222724

Start: 1712792

End: 1713688

Strand: Reverse

Name: ccrA [H]

Synonym: Gmet_1512

Alternate gene names: 78222724

Gene position: 1713688-1712792 (Counterclockwise)

Preceding gene: 78222726

Following gene: 78222723

Centisome position: 42.87

GC content: 60.65

Gene sequence:

>897_bases
ATGAAAAGGCACTTCCTGCTGTTTCCAATCCTGGTCCTGATGCTGGCAACACCGGCTTTGGCCGATCTCACCAAAATCAG
CGACAACGTATACTCCTACGTGGGGGCGACGGATGCCTCGCCAACTCACAGCTTTGCCGCCAACGCCGGGATCGTCATCG
GCCGCGACGGCGTGCTGGTTGTGGATACCCTGCTCTCAGCCAAGGAGGGGGAGCGGTTCCTCGCCGACATCCGCAAGGTC
ACGACCAAGCCGATCCGCTATGTGGTCGACACCCACATCCACCTGGACCATGCCTTGGGCAACTGCGTCTTTGCCAGGGA
AGGCGCTACCATCATCTCCCATGAAGCCGAGCGGTCCTCGCTGGCCCAAAACGGGGCCGAGATTCTCAGAAAAGCCGGCG
ACTATGGGCTGAAACCGGAAGACATGGTCGGCACCGAGATCGTCCTGCCGTCGCTGACGTTCAGCGACCGACTGACCATC
GACCTGGGGGGCGAGACGGTGGAACTGCTCCGTATCGCCCCTTCCCATACCGCGGGGAGCACCATTGTCTACCTGCCGGC
ACAGAAACTCCTCTTCAGCGGCGATATCCTCTTCACCGATTTCCACCCCTTCTTTGCCGACGGCGACCTCCCCAACTGGG
CAAAGACCCTCGACGCCATTCTCGCCATGGACGTGGAGCGAATCGTCCCGGGTCACGGCCCCCTTTCGACGAAAAAGGAT
CTGCAGGAGATGAAGGAATACTTGCGGCTTTTCGACGCCAAGGCACGGGATCTGGTGGCAACGGGCAAGGATGTCGACAC
CGTTGCTGCGCAGCTCGCGAAGGTGCTGCCCAAGCGGACTCTGGCGGAGTGGATGATTCCCGCCAATCTGAAGGCCCGCT
ACCTGCATAAACAGTGA

Upstream 100 bases:

>100_bases
CTGTCCCAATGGACAGGTGATTTTTAGGGGACATTAACATATAGTGCATCATTCCGGCAAATGATTGGCCGTACCGAAAT
GCTCGAGAGGAGAACCATTG

Downstream 100 bases:

>100_bases
GAAGCACACATGTCTGCGAGAGTAACGGATTGGATGACTACCTTGTCGAGACTCCTCGTGCTACTCGTGCTCGCAACGAA
TATCTTCGGCTGTTCCCTAA

Product: Beta-lactamase-like

Products: NA

Alternate protein names: Cephalosporinase; Imipenem-cefoxitin hydrolyzing enzyme; Penicillinase [H]

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MKRHFLLFPILVLMLATPALADLTKISDNVYSYVGATDASPTHSFAANAGIVIGRDGVLVVDTLLSAKEGERFLADIRKV
TTKPIRYVVDTHIHLDHALGNCVFAREGATIISHEAERSSLAQNGAEILRKAGDYGLKPEDMVGTEIVLPSLTFSDRLTI
DLGGETVELLRIAPSHTAGSTIVYLPAQKLLFSGDILFTDFHPFFADGDLPNWAKTLDAILAMDVERIVPGHGPLSTKKD
LQEMKEYLRLFDAKARDLVATGKDVDTVAAQLAKVLPKRTLAEWMIPANLKARYLHKQ

Sequences:

>Translated_298_residues
MKRHFLLFPILVLMLATPALADLTKISDNVYSYVGATDASPTHSFAANAGIVIGRDGVLVVDTLLSAKEGERFLADIRKV
TTKPIRYVVDTHIHLDHALGNCVFAREGATIISHEAERSSLAQNGAEILRKAGDYGLKPEDMVGTEIVLPSLTFSDRLTI
DLGGETVELLRIAPSHTAGSTIVYLPAQKLLFSGDILFTDFHPFFADGDLPNWAKTLDAILAMDVERIVPGHGPLSTKKD
LQEMKEYLRLFDAKARDLVATGKDVDTVAAQLAKVLPKRTLAEWMIPANLKARYLHKQ
>Mature_298_residues
MKRHFLLFPILVLMLATPALADLTKISDNVYSYVGATDASPTHSFAANAGIVIGRDGVLVVDTLLSAKEGERFLADIRKV
TTKPIRYVVDTHIHLDHALGNCVFAREGATIISHEAERSSLAQNGAEILRKAGDYGLKPEDMVGTEIVLPSLTFSDRLTI
DLGGETVELLRIAPSHTAGSTIVYLPAQKLLFSGDILFTDFHPFFADGDLPNWAKTLDAILAMDVERIVPGHGPLSTKKD
LQEMKEYLRLFDAKARDLVATGKDVDTVAAQLAKVLPKRTLAEWMIPANLKARYLHKQ

Specific function: Can hydrolyze carbapenem compounds [H]

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-B beta-lactamase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001018
- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: =3.5.2.6 [H]

Molecular weight: Translated: 32654; Mature: 32654

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS01137 TATD_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRHFLLFPILVLMLATPALADLTKISDNVYSYVGATDASPTHSFAANAGIVIGRDGVLV
CCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCEEECCCCEEE
VDTLLSAKEGERFLADIRKVTTKPIRYVVDTHIHLDHALGNCVFAREGATIISHEAERSS
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEEEHHHHCCEEEECCCCEEEECHHHHHH
LAQNGAEILRKAGDYGLKPEDMVGTEIVLPSLTFSDRLTIDLGGETVELLRIAPSHTAGS
HHHHHHHHHHHCCCCCCCCCHHCCCEEEECCCCCCCEEEEEECCCEEEEEEECCCCCCCC
TIVYLPAQKLLFSGDILFTDFHPFFADGDLPNWAKTLDAILAMDVERIVPGHGPLSTKKD
EEEEECHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
LQEMKEYLRLFDAKARDLVATGKDVDTVAAQLAKVLPKRTLAEWMIPANLKARYLHKQ
HHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCC
>Mature Secondary Structure
MKRHFLLFPILVLMLATPALADLTKISDNVYSYVGATDASPTHSFAANAGIVIGRDGVLV
CCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCEEECCCCEEE
VDTLLSAKEGERFLADIRKVTTKPIRYVVDTHIHLDHALGNCVFAREGATIISHEAERSS
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEEEHHHHCCEEEECCCCEEEECHHHHHH
LAQNGAEILRKAGDYGLKPEDMVGTEIVLPSLTFSDRLTIDLGGETVELLRIAPSHTAGS
HHHHHHHHHHHCCCCCCCCCHHCCCEEEECCCCCCCEEEEEECCCEEEEEEECCCCCCCC
TIVYLPAQKLLFSGDILFTDFHPFFADGDLPNWAKTLDAILAMDVERIVPGHGPLSTKKD
EEEEECHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
LQEMKEYLRLFDAKARDLVATGKDVDTVAAQLAKVLPKRTLAEWMIPANLKARYLHKQ
HHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2121094; 1956298; 2110145; 8805566; 9416622; 9578564; 10210203 [H]