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The map label for this gene is hybB [C]

Identifier: 78222279

GI number: 78222279

Start: 1181143

End: 1182348

Strand: Direct

Name: hybB [C]

Synonym: Gmet_1061

Alternate gene names: 78222279

Gene position: 1181143-1182348 (Clockwise)

Preceding gene: 78222278

Following gene: 78222280

Centisome position: 29.55

GC content: 62.44

Gene sequence:

>1206_bases
ATGACCGCGGCACGCATTGTCATGAATGAAATCAAAGGGTACCATCGCTTCATCAAGTTTCTGATGGTCCTCGTGGGGGG
GGCGGCTTTGGCCTCCGCTGTCCGCTTCATCTTCGGCCTCGGGGCCACCACCAACCTGAATGACCTCTACCCGTGGGGAC
TCTGGATCTCCTTCGACGTGGTCACCGCCGTCCCCCTGGCGGCCGGCGCCTTCACTATCGGCATCGTGGCCCACGTCTTC
CACATCAAGAAGCTGGAGCCCCTGGTCCGGCCGGCCATCGTCACCGGCTTCCTGGGCTACTCCCTGGTCTGCGTGGGCCT
GCTCCTCGACCTGGGGCAGCCCCAGCGGGGCCCCTACGTCCTCTTCAACTGGAACGTCCACTCCCCCATGTTCGAGGTCT
CCATGTGTGTCATGGCGTACACCACGGTCCTCTTCCTGGAGTTCCTCCACCCGGTGAGCGAGCGGTTTGGCTGGCACATC
CCGCTGCGGCTCCTCCGGACCCTGGAGCTGCCGTTCGCCATCCTGGCGGCCATGATCTCCACGCTCCACCAGTCGACCCT
GGGGACCTTCTTCCTCATCGCCGTCGACAAGCTCCACAACCTCTGGTACAATCCGCTCCTGCCGCTTCAGTTCTGGCTTT
CCGCCATCTTCACCGGCCTCTCCATCGTTATCTTCGAGGCGAGCCTCGTGCACAAGTACATGGGGCAGCCCGACGAGTCC
GACCTGCTGGCCACGCTGACGAAGATCATCCCCTGGATCATGGGGGTCTACATGCTGGTGAAGGTCTATGCCCTGGCGTC
CCTCTCCCACGGACCCCTCTTCGACCGACCGGTCCTGACGGCCCTCTTTGCGGTTGAGGTGATCGTGGGGCTCCTGATTC
CGTTCGGCATGTTCCTCACGAAACGGATCAGGACCGACAAGCAGATGCAGCTTCGGGCCGCTTCCTTTGTCATCGCCGGC
CTCGTGCTGAACCGCTTCAACGTCTCCATGTTCGCCATGCACCAGCCCGGCCAGCCGGCATATTTCCCGAATTTCATCGA
ATCGGTGGTAACCATCGGCATCATCGCGGCCCACATCCTCTTCTTCGTGCTCGTGGCCAAGTACTTCCCCATCTTCGAGC
ACCACCCCGAGGCCACCGACTACACCATCCCCGACCGCTTCCGCAAGATCGAGAAGCATGGGCATGGGGTGGCGAGCGAG
GCGTAG

Upstream 100 bases:

>100_bases
CCGTTGGCGGCACCCTGTCGCTGGTCACCTGGTTCCAGCACCGCAAGGACCGGGTGAGGCGCGAGGAAGAGGAACGGAAC
AGCCGGAAGGAGGGGAACCA

Downstream 100 bases:

>100_bases
GTTTCCATGAAAACCATCCACATCTACACCAACGGCCGTTTCGAAGAAAAACAGTCGGGCATCGTCCGGGAATTCCCCCT
GGTGCTCCACGTGAACGGCC

Product: polysulphide reductase, NrfD

Products: NA

Alternate protein names: HMC operon ORF 3 [H]

Number of amino acids: Translated: 401; Mature: 400

Protein sequence:

>401_residues
MTAARIVMNEIKGYHRFIKFLMVLVGGAALASAVRFIFGLGATTNLNDLYPWGLWISFDVVTAVPLAAGAFTIGIVAHVF
HIKKLEPLVRPAIVTGFLGYSLVCVGLLLDLGQPQRGPYVLFNWNVHSPMFEVSMCVMAYTTVLFLEFLHPVSERFGWHI
PLRLLRTLELPFAILAAMISTLHQSTLGTFFLIAVDKLHNLWYNPLLPLQFWLSAIFTGLSIVIFEASLVHKYMGQPDES
DLLATLTKIIPWIMGVYMLVKVYALASLSHGPLFDRPVLTALFAVEVIVGLLIPFGMFLTKRIRTDKQMQLRAASFVIAG
LVLNRFNVSMFAMHQPGQPAYFPNFIESVVTIGIIAAHILFFVLVAKYFPIFEHHPEATDYTIPDRFRKIEKHGHGVASE
A

Sequences:

>Translated_401_residues
MTAARIVMNEIKGYHRFIKFLMVLVGGAALASAVRFIFGLGATTNLNDLYPWGLWISFDVVTAVPLAAGAFTIGIVAHVF
HIKKLEPLVRPAIVTGFLGYSLVCVGLLLDLGQPQRGPYVLFNWNVHSPMFEVSMCVMAYTTVLFLEFLHPVSERFGWHI
PLRLLRTLELPFAILAAMISTLHQSTLGTFFLIAVDKLHNLWYNPLLPLQFWLSAIFTGLSIVIFEASLVHKYMGQPDES
DLLATLTKIIPWIMGVYMLVKVYALASLSHGPLFDRPVLTALFAVEVIVGLLIPFGMFLTKRIRTDKQMQLRAASFVIAG
LVLNRFNVSMFAMHQPGQPAYFPNFIESVVTIGIIAAHILFFVLVAKYFPIFEHHPEATDYTIPDRFRKIEKHGHGVASE
A
>Mature_400_residues
TAARIVMNEIKGYHRFIKFLMVLVGGAALASAVRFIFGLGATTNLNDLYPWGLWISFDVVTAVPLAAGAFTIGIVAHVFH
IKKLEPLVRPAIVTGFLGYSLVCVGLLLDLGQPQRGPYVLFNWNVHSPMFEVSMCVMAYTTVLFLEFLHPVSERFGWHIP
LRLLRTLELPFAILAAMISTLHQSTLGTFFLIAVDKLHNLWYNPLLPLQFWLSAIFTGLSIVIFEASLVHKYMGQPDESD
LLATLTKIIPWIMGVYMLVKVYALASLSHGPLFDRPVLTALFAVEVIVGLLIPFGMFLTKRIRTDKQMQLRAASFVIAGL
VLNRFNVSMFAMHQPGQPAYFPNFIESVVTIGIIAAHILFFVLVAKYFPIFEHHPEATDYTIPDRFRKIEKHGHGVASEA

Specific function: HMWC (high-molecular-weight cytochrome c), ORF2, ORF3, ORF4, ORF5 and ORF6 in the HMC operon form a transmembrane protein complex that allows electron flow from the periplasmic hydrogenase to the cytoplasmic enzymes that catalyze reduction of sulfates [H]

COG id: COG5557

COG function: function code C; Polysulphide reductase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nrfD family [H]

Homologues:

Organism=Escherichia coli, GI2367183, Length=343, Percent_Identity=32.3615160349854, Blast_Score=184, Evalue=1e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005614 [H]

Pfam domain/function: PF03916 NrfD [H]

EC number: NA

Molecular weight: Translated: 44889; Mature: 44758

Theoretical pI: Translated: 9.18; Mature: 9.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TAARIVMNEIKGYHRFIKFLMVLVGGAALASAVRFIFGLGATTNLNDLYPWGLWISFDV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHH
VTAVPLAAGAFTIGIVAHVFHIKKLEPLVRPAIVTGFLGYSLVCVGLLLDLGQPQRGPYV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEE
LFNWNVHSPMFEVSMCVMAYTTVLFLEFLHPVSERFGWHIPLRLLRTLELPFAILAAMIS
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHH
TLHQSTLGTFFLIAVDKLHNLWYNPLLPLQFWLSAIFTGLSIVIFEASLVHKYMGQPDES
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
DLLATLTKIIPWIMGVYMLVKVYALASLSHGPLFDRPVLTALFAVEVIVGLLIPFGMFLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KRIRTDKQMQLRAASFVIAGLVLNRFNVSMFAMHQPGQPAYFPNFIESVVTIGIIAAHIL
HHHCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHH
FFVLVAKYFPIFEHHPEATDYTIPDRFRKIEKHGHGVASEA
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8335628 [H]