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The map label for this gene is fdhD [H]

Identifier: 78222280

GI number: 78222280

Start: 1182355

End: 1183794

Strand: Direct

Name: fdhD [H]

Synonym: Gmet_1062

Alternate gene names: 78222280

Gene position: 1182355-1183794 (Clockwise)

Preceding gene: 78222279

Following gene: 78222281

Centisome position: 29.58

GC content: 66.11

Gene sequence:

>1440_bases
ATGAAAACCATCCACATCTACACCAACGGCCGTTTCGAAGAAAAACAGTCGGGCATCGTCCGGGAATTCCCCCTGGTGCT
CCACGTGAACGGCCGGGAGATCGCGACGCTGATCTCTTCTCCCCACGATCTCCGGTTTCTCGTTGCAGGGTTCCTTCGCA
ACCAGGGGTTCGTGGAGCGGGCCGAGGATTTCCACATGCTGGCCGTCTGCGACGACTTCGGCATCGCCAACGCGCGGATC
AGGGGCGAGCTGCCGGAGCGGCTGAAGCCGGTCCTCACCAGCGGCTGCGGCACGGGGGTCACCTTTACCCTGGAGACCCC
GAAAATCCCTCCTCCCCTGGCCCTGCCTGCTATCACCACCGACGCCGTGTTTCGCCTCATGGAGGAGCTGGCGCGGCGGG
CCGACAACTACCGGAGCCACGGCGGCATCCACTCCGCGGCCGTGGGGGACGGGGAGGGGAACCTCCTCCTCTTCGCCGAG
GACATCGGCCGCCACAACACCCTTGACCGGATCGCCGGCGAGGCCCTCTTCAAGGGGATCGACCTGGCCGGGACAATCCT
TGTCACCTCGGGGCGGGTCTCCACCGAAATGGCTGCCAAGTGCGCCAGGCTCGGAATAGCGCTCATCGCCTCCCGCACCT
CCGCCACCGACATGGCGGTGAAGATGTGCGACGAGGCGGGGATTCCCCTCATCGGTTATGTCCGGGGAGGGAAGTTCACG
GTGTATGCCCACCACGAGCGGCTGGCGATGGCGCCACCCGTGGGGGCGATTCATGAACTGCCCCTACCTGCGTCCGCACA
GGGGAGGCGCATTCCCGGCATCACCGGCGTCATCCTCGCCGGCGGGCAGTCGCGCCGCATGGGGAGCAACAAGGCGCTCC
TTCCCTACAAGGGGGGGCGCTTCATCGAGGCCATCCATCGGCAGCTGGCCGAGATCTTCGACGAGGTGCTCCTCGTCACC
AACAACCCGGAGCAGTATGATTTTCTCCCCTGCCGGAAAGTGGCCGACATCCACCCGGGGATGGGGGCACTGGCCGGCAT
CCATGCGGGGCTGCACCACGCCGCCAACCCTGCCGCCTTCATGGTCGCCTGCGACATGCCGTACCTGAACAGCGACCTGA
TCCGGCATCTGGCCACCCTGGCCGACCCGGGCGGGGTCCTCATTCCCGAAAGCCCGGCGGGGCTGGAACCGCTCCATGCG
GTCTACGGCAAAGGGTGCCTTGCCGCCATCGAGACAACGCTCCTGTCGGGCGAACGGCGGATTGTTTCGTTCTTCGGCCG
GACCAACGTCAACCGGGTCAACGCCGAGCAGGTGGCCCTCTTCGATCCGGACTACGCCACCTTCAGCAACATCAATACCC
CCGTGGACTATTACCGGCTTCGGGATGGCGAGCGGGACGAACTCGACGCCGCTCTCGGCGCCGACCGCATCGCGGGGTGA

Upstream 100 bases:

>100_bases
CTTCGAGCACCACCCCGAGGCCACCGACTACACCATCCCCGACCGCTTCCGCAAGATCGAGAAGCATGGGCATGGGGTGG
CGAGCGAGGCGTAGGTTTCC

Downstream 100 bases:

>100_bases
TACAATACTCTGCGTCGATACTCTAATTTGCCACTAAAGGAGATTCACCCATGTTCGGATTCGGAATGCCAGAAATGATA
ATCGTCCTCGTCATTGCCCT

Product: formate dehydrogenase subunit FdhD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 479; Mature: 479

Protein sequence:

>479_residues
MKTIHIYTNGRFEEKQSGIVREFPLVLHVNGREIATLISSPHDLRFLVAGFLRNQGFVERAEDFHMLAVCDDFGIANARI
RGELPERLKPVLTSGCGTGVTFTLETPKIPPPLALPAITTDAVFRLMEELARRADNYRSHGGIHSAAVGDGEGNLLLFAE
DIGRHNTLDRIAGEALFKGIDLAGTILVTSGRVSTEMAAKCARLGIALIASRTSATDMAVKMCDEAGIPLIGYVRGGKFT
VYAHHERLAMAPPVGAIHELPLPASAQGRRIPGITGVILAGGQSRRMGSNKALLPYKGGRFIEAIHRQLAEIFDEVLLVT
NNPEQYDFLPCRKVADIHPGMGALAGIHAGLHHAANPAAFMVACDMPYLNSDLIRHLATLADPGGVLIPESPAGLEPLHA
VYGKGCLAAIETTLLSGERRIVSFFGRTNVNRVNAEQVALFDPDYATFSNINTPVDYYRLRDGERDELDAALGADRIAG

Sequences:

>Translated_479_residues
MKTIHIYTNGRFEEKQSGIVREFPLVLHVNGREIATLISSPHDLRFLVAGFLRNQGFVERAEDFHMLAVCDDFGIANARI
RGELPERLKPVLTSGCGTGVTFTLETPKIPPPLALPAITTDAVFRLMEELARRADNYRSHGGIHSAAVGDGEGNLLLFAE
DIGRHNTLDRIAGEALFKGIDLAGTILVTSGRVSTEMAAKCARLGIALIASRTSATDMAVKMCDEAGIPLIGYVRGGKFT
VYAHHERLAMAPPVGAIHELPLPASAQGRRIPGITGVILAGGQSRRMGSNKALLPYKGGRFIEAIHRQLAEIFDEVLLVT
NNPEQYDFLPCRKVADIHPGMGALAGIHAGLHHAANPAAFMVACDMPYLNSDLIRHLATLADPGGVLIPESPAGLEPLHA
VYGKGCLAAIETTLLSGERRIVSFFGRTNVNRVNAEQVALFDPDYATFSNINTPVDYYRLRDGERDELDAALGADRIAG
>Mature_479_residues
MKTIHIYTNGRFEEKQSGIVREFPLVLHVNGREIATLISSPHDLRFLVAGFLRNQGFVERAEDFHMLAVCDDFGIANARI
RGELPERLKPVLTSGCGTGVTFTLETPKIPPPLALPAITTDAVFRLMEELARRADNYRSHGGIHSAAVGDGEGNLLLFAE
DIGRHNTLDRIAGEALFKGIDLAGTILVTSGRVSTEMAAKCARLGIALIASRTSATDMAVKMCDEAGIPLIGYVRGGKFT
VYAHHERLAMAPPVGAIHELPLPASAQGRRIPGITGVILAGGQSRRMGSNKALLPYKGGRFIEAIHRQLAEIFDEVLLVT
NNPEQYDFLPCRKVADIHPGMGALAGIHAGLHHAANPAAFMVACDMPYLNSDLIRHLATLADPGGVLIPESPAGLEPLHA
VYGKGCLAAIETTLLSGERRIVSFFGRTNVNRVNAEQVALFDPDYATFSNINTPVDYYRLRDGERDELDAALGADRIAG

Specific function: Necessary for formate dehydrogenase activity [H]

COG id: COG1526

COG function: function code C; Uncharacterized protein required for formate dehydrogenase activity

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fdhD family [H]

Homologues:

Organism=Escherichia coli, GI1790329, Length=242, Percent_Identity=26.8595041322314, Blast_Score=89, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003786 [H]

Pfam domain/function: PF02634 FdhD-NarQ [H]

EC number: NA

Molecular weight: Translated: 51661; Mature: 51661

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTIHIYTNGRFEEKQSGIVREFPLVLHVNGREIATLISSPHDLRFLVAGFLRNQGFVER
CCEEEEEECCCCCHHHCCCEEECCEEEEECCHHHHHHHCCCCHHHHHHHHHHHCCCCHHH
AEDFHMLAVCDDFGIANARIRGELPERLKPVLTSGCGTGVTFTLETPKIPPPLALPAITT
CCCCEEEEEECCCCCCCCEECCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCH
DAVFRLMEELARRADNYRSHGGIHSAAVGDGEGNLLLFAEDIGRHNTLDRIAGEALFKGI
HHHHHHHHHHHHHHHCHHHCCCEEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHCC
DLAGTILVTSGRVSTEMAAKCARLGIALIASRTSATDMAVKMCDEAGIPLIGYVRGGKFT
CCEEEEEEECCCCHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHCCCCEEEEEECCEEE
VYAHHERLAMAPPVGAIHELPLPASAQGRRIPGITGVILAGGQSRRMGSNKALLPYKGGR
EEEECCCEEECCCCCCHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCEEECCCCCH
FIEAIHRQLAEIFDEVLLVTNNPEQYDFLPCRKVADIHPGMGALAGIHAGLHHAANPAAF
HHHHHHHHHHHHHHHEEEEECCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHCCCCEEE
MVACDMPYLNSDLIRHLATLADPGGVLIPESPAGLEPLHAVYGKGCLAAIETTLLSGERR
EEEECCCCCCHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHCCHHHHHHHHHHHCCCHH
IVSFFGRTNVNRVNAEQVALFDPDYATFSNINTPVDYYRLRDGERDELDAALGADRIAG
HHHHHCCCCCCEECCCEEEEECCCCHHHCCCCCCHHHHEECCCCHHHHHHHHCCHHCCC
>Mature Secondary Structure
MKTIHIYTNGRFEEKQSGIVREFPLVLHVNGREIATLISSPHDLRFLVAGFLRNQGFVER
CCEEEEEECCCCCHHHCCCEEECCEEEEECCHHHHHHHCCCCHHHHHHHHHHHCCCCHHH
AEDFHMLAVCDDFGIANARIRGELPERLKPVLTSGCGTGVTFTLETPKIPPPLALPAITT
CCCCEEEEEECCCCCCCCEECCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCH
DAVFRLMEELARRADNYRSHGGIHSAAVGDGEGNLLLFAEDIGRHNTLDRIAGEALFKGI
HHHHHHHHHHHHHHHCHHHCCCEEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHCC
DLAGTILVTSGRVSTEMAAKCARLGIALIASRTSATDMAVKMCDEAGIPLIGYVRGGKFT
CCEEEEEEECCCCHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHCCCCEEEEEECCEEE
VYAHHERLAMAPPVGAIHELPLPASAQGRRIPGITGVILAGGQSRRMGSNKALLPYKGGR
EEEECCCEEECCCCCCHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCEEECCCCCH
FIEAIHRQLAEIFDEVLLVTNNPEQYDFLPCRKVADIHPGMGALAGIHAGLHHAANPAAF
HHHHHHHHHHHHHHHEEEEECCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHCCCCEEE
MVACDMPYLNSDLIRHLATLADPGGVLIPESPAGLEPLHAVYGKGCLAAIETTLLSGERR
EEEECCCCCCHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHCCHHHHHHHHHHHCCCHH
IVSFFGRTNVNRVNAEQVALFDPDYATFSNINTPVDYYRLRDGERDELDAALGADRIAG
HHHHHCCCCCCEECCCEEEEECCCCHHHCCCCCCHHHHEECCCCHHHHHHHHCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA