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The map label for this gene is gmhB [H]

Identifier: 78222143

GI number: 78222143

Start: 1018089

End: 1018667

Strand: Direct

Name: gmhB [H]

Synonym: Gmet_0923

Alternate gene names: 78222143

Gene position: 1018089-1018667 (Clockwise)

Preceding gene: 78222142

Following gene: 78222144

Centisome position: 25.47

GC content: 66.67

Gene sequence:

>579_bases
ATGGTGAGGAGTGAGGAGGGCCGCGCGGCCGTCTTTCTTGACCGGGACGGCACCATCAACGTGGAGAAGGAGTACCTCCA
CCGGGCCGAGGAGTTCGAGTTCGTCCCCGGGGCGCCGGAAGCGATCCGGCTCCTGAATGAAGCCGGATTTCTGGTGGTGG
TGGTGACCAACCAGTCGGGGGTTGCCCGCGGCTACTACGACGAGGCGGCGGTCCACCGTCTCCACCGCTTCGTGGACAAC
GAGCTGGCAAAGGCCGGCGCCTCCATCGACGCCTACTATCTCTGCCCCCATCATCCCCGCCACGGCATCGGCCCATACCT
CACCGAGTGTGCCTGCCGTAAGCCCCTTCCCGGCATGCTCCTCGCCGCGGCACGGGATCTGGGCATAGACCTTGCCCGCT
CCTGGATCGTCGGCGACAAGGCGGCCGACGTGGAAGCGGGTATCGCCGCCGGCTGCCGCCCCCTGCTGGTCAGGACCGGC
TACGGTATTTCGGAGGCTGGACAGGTCCCCTCTGACGTGACGGTCTGCGACGACCTCCTTGCCGCGGCCCGGGTGATTCT
GGCAAGAACCCAAGAATGA

Upstream 100 bases:

>100_bases
GGGAAGGATGTGGTGGAGTCCTACGGCGGCAGGGTCGAGCTCGTGACCTTCGTGGATGGCCGCTCCACCACGAACATCAT
CGATAAGATTCTGAGGGCCT

Downstream 100 bases:

>100_bases
TGGACAGCCCCAGAAGGGGGGAGTTACGGTTTGACGCTCTTTTCCCTGCTGTGCTATAACCGCTTGTCAGAAGGACCATT
TTGATTCAATCCCCGGTATG

Product: D-alpha,beta-D-heptose 1,7-bisphosphate phosphatase

Products: NA

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [H]

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MVRSEEGRAAVFLDRDGTINVEKEYLHRAEEFEFVPGAPEAIRLLNEAGFLVVVVTNQSGVARGYYDEAAVHRLHRFVDN
ELAKAGASIDAYYLCPHHPRHGIGPYLTECACRKPLPGMLLAAARDLGIDLARSWIVGDKAADVEAGIAAGCRPLLVRTG
YGISEAGQVPSDVTVCDDLLAAARVILARTQE

Sequences:

>Translated_192_residues
MVRSEEGRAAVFLDRDGTINVEKEYLHRAEEFEFVPGAPEAIRLLNEAGFLVVVVTNQSGVARGYYDEAAVHRLHRFVDN
ELAKAGASIDAYYLCPHHPRHGIGPYLTECACRKPLPGMLLAAARDLGIDLARSWIVGDKAADVEAGIAAGCRPLLVRTG
YGISEAGQVPSDVTVCDDLLAAARVILARTQE
>Mature_192_residues
MVRSEEGRAAVFLDRDGTINVEKEYLHRAEEFEFVPGAPEAIRLLNEAGFLVVVVTNQSGVARGYYDEAAVHRLHRFVDN
ELAKAGASIDAYYLCPHHPRHGIGPYLTECACRKPLPGMLLAAARDLGIDLARSWIVGDKAADVEAGIAAGCRPLLVRTG
YGISEAGQVPSDVTVCDDLLAAARVILARTQE

Specific function: Converts the D-glycero-alpha-D-manno-heptose 1,7- bisphosphate intermediate into D-glycero-alpha-D-manno-heptose 1- phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=164, Percent_Identity=46.9512195121951, Blast_Score=154, Evalue=3e-39,
Organism=Escherichia coli, GI87082027, Length=138, Percent_Identity=28.9855072463768, Blast_Score=73, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR004446
- InterPro:   IPR006543
- InterPro:   IPR013954 [H]

Pfam domain/function: PF08645 PNK3P [H]

EC number: NA

Molecular weight: Translated: 20770; Mature: 20770

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRSEEGRAAVFLDRDGTINVEKEYLHRAEEFEFVPGAPEAIRLLNEAGFLVVVVTNQSG
CCCCCCCCEEEEEECCCCEECCHHHHHHHHHCCCCCCCHHHHHHHHCCCEEEEEEECCCC
VARGYYDEAAVHRLHRFVDNELAKAGASIDAYYLCPHHPRHGIGPYLTECACRKPLPGML
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHCCCCCHHH
LAAARDLGIDLARSWIVGDKAADVEAGIAAGCRPLLVRTGYGISEAGQVPSDVTVCDDLL
HHHHHHHCHHHHHHHHCCCCCCCCHHHHHHCCCEEEEECCCCCCCCCCCCCCHHHHHHHH
AAARVILARTQE
HHHHHHHHHCCC
>Mature Secondary Structure
MVRSEEGRAAVFLDRDGTINVEKEYLHRAEEFEFVPGAPEAIRLLNEAGFLVVVVTNQSG
CCCCCCCCEEEEEECCCCEECCHHHHHHHHHCCCCCCCHHHHHHHHCCCEEEEEEECCCC
VARGYYDEAAVHRLHRFVDNELAKAGASIDAYYLCPHHPRHGIGPYLTECACRKPLPGML
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHCCCCCHHH
LAAARDLGIDLARSWIVGDKAADVEAGIAAGCRPLLVRTGYGISEAGQVPSDVTVCDDLL
HHHHHHHCHHHHHHHHCCCCCCCCHHHHHHCCCEEEEECCCCCCCCCCCCCCHHHHHHHH
AAARVILARTQE
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11466286; 12101286 [H]