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The map label for this gene is 78221821

Identifier: 78221821

GI number: 78221821

Start: 669424

End: 671562

Strand: Direct

Name: 78221821

Synonym: Gmet_0600

Alternate gene names: NA

Gene position: 669424-671562 (Clockwise)

Preceding gene: 304570575

Following gene: 78221822

Centisome position: 16.75

GC content: 61.01

Gene sequence:

>2139_bases
ATGAAGACTGAAGATGGCTCTGAAAGGGGGCGCCTGACCGTTTTTGCGCTGCTGGCACTGTTCCTGTTCGTGCCGATTAT
GCAGCCCGAGGCCCATGCGCTTGTTGAGAACAATTGCAGGGGGTGTCATAACGATGCGCAGGGGAAAACCGCGGACCGGC
ACCATGCGCTGCTCAGTCTAGGAAAGCAATGTCTTGACTGCCACCAGATGGTTGGTCCGTCCGGAAGTCAGACTCCTGTT
GTGGTTCGCGATTGCATTGCATGTCATGGCGACCTGATTCACCAGGGACGACACCATCAACTGATCGCTGAGCGCGGTAA
ACAATGCCTTGACTGTCACCAGATAGTTGTGGACGCTTCCGGCGCCAATACGCCCGTTGTGGTCCGGGACTGCAGTGTCT
GTCATGCGACCATGAACCCCAAGACCAATCACAATAATGCCATGGCCGATGTCAGTTGCGCCCAGTGCCATAACCTTGGT
GTGGTGAACGAGCATCTTTCCCGCACGTCCACCTGCTATACCTGTCACAGCAGCGTTAATGTCACGGTGCAACAGACTAT
ACTTTCCGCAAAGACAGGGGTCGTGGTCACCTGTACTTCCTGCCACGTTGGTTTTGATCACGTAGCCCAGCACAACATGG
TGGTAACGCCTGCGGACTGCGCAGGGTGCCACACTCAGGGAGTGGTTTACGAGCACACGAACCGGACCTCCACCTGCGCC
ACCTGCCACCAGAGCACCAACGCCACCGTTCAGAAAACGATCACCGACGGTCGGAACAATATCCAGGTATCCTGCGCCAA
CTGCCACGGCACGGTGAACCACATTGCCCAGCACGACATGGCCCAGACCGCGGCCGAGTGCGCCCAGTGCCACACCAAGA
GTGTCCTTGACGAGCACCTGACCCGGACTTCCACCTGCGCCACCTGCCACTCCAGCTCCCGGGTTGAAGTCCAGAACGCC
ATCACCGCCGGCCGTGCCGGCACGGTGGTCAACTGCGTCACCTGCCACGGCCAGTACAACCATCCCACGGCCCACACCGG
CAAGGTCAGCGCTCCCTACGCCGACTGCAACACCTGCCACATCACCAACCTGACCGACCTGCACGCCCAGCGGGGCTTCC
AGTGCGCCGCCTGCCACGCCAGCACCAACACGGCCATAACCGCGGCTGTTCAGAAAGGTCTCGGTGGCCAACCGGTTGTC
TGTGCCGACTGCCACAACGCCATCGGCGGCTTCGGCAACCATGCGAAGCAGCACGACATGGTCACCCTCAACAGCACCAC
CGGCTTCATCGCCGCCCATGAAGAGAAAATGGTTTACTGCTTCACCTGTCACAACAACACTAACGCCGGCTACCAGAAAG
CCATCAACGATGGCATGGCCGGCATACCGCAGACCTGCACCTCCTGCCACGCCGCTTACGGCAACCAGCCTCCGGTGGCC
AACGCCGGCGCCAATGTGACCACCACCGTCAACAAGGCAGTGACCCTCTCCGGGGCCGCTTCCAGCGACCCGGACGGCAC
CATCGTATCGTACGCCTGGACCTTCGGCGACGGCACCACCGGCAGTGGCGTCTCCGTCACCAAGACCTACGCCACGGCCG
GCACCTACACCGTGACCCTGACCGTCACCGACAACGCCGGCGCCAGCGCCAGCGCCACCACCATCGTCACCGTCCAGGCG
GCCCCGACCAGCAGCTCGGTCTTTGCCGACCAGGTTCTGTCCATGCAGCGGCTCTACTCCGTCACCTCCTCGGACAGCAA
CAGCAGCGACGTCACCGCCAACTTCCGCGACGGCAACACTACCGACCGCTACCTGCTGCAGTATGGCAGCAGCGGCAGCA
ACTACGTCATCGCCATGAAACTGAACCGCGATGCCCTGACCGCCACCAAGGTGGTGCTGCGGGTGTATGTCTCCTCCATC
AGTTCCTCGCGGACCTTGAGGATCTACCCGTACCAGTCCAACGGAACCTCGGTGAACACCCGCTACTACACGAGCTACAG
CACGAGCAGCACCGGGTGGAAGGATATCGACGTCACTTCCATCGCCCAGCAGATGAACGGCTACGGCTGGATGAAGTTCC
GTGTCACCCCCACTTCGAACAGCCTCTACGTTGCCGAGGGTGCCTTCCAGGTACAGTAA

Upstream 100 bases:

>100_bases
TGTGTCACAAATAACTAATATTCGTTAATCAATGGTTGGGGCTTGATTCTTCTCGTTGGTCGTGTAAAAGGCTGTGTCAC
GGAGTTGAAAGGGGAAAAAG

Downstream 100 bases:

>100_bases
CGTAGTGAGACTAATCAGAGTCCAGGAACTGAAAGGAGAAACGAAATGAAGCGCATCGGGATCACATTCATCGCGCTCCT
CGCTTTGGCCGCTCCGGCCA

Product: PKD

Products: NA

Alternate protein names: API; Lysyl endopeptidase; Protease I [H]

Number of amino acids: Translated: 712; Mature: 712

Protein sequence:

>712_residues
MKTEDGSERGRLTVFALLALFLFVPIMQPEAHALVENNCRGCHNDAQGKTADRHHALLSLGKQCLDCHQMVGPSGSQTPV
VVRDCIACHGDLIHQGRHHQLIAERGKQCLDCHQIVVDASGANTPVVVRDCSVCHATMNPKTNHNNAMADVSCAQCHNLG
VVNEHLSRTSTCYTCHSSVNVTVQQTILSAKTGVVVTCTSCHVGFDHVAQHNMVVTPADCAGCHTQGVVYEHTNRTSTCA
TCHQSTNATVQKTITDGRNNIQVSCANCHGTVNHIAQHDMAQTAAECAQCHTKSVLDEHLTRTSTCATCHSSSRVEVQNA
ITAGRAGTVVNCVTCHGQYNHPTAHTGKVSAPYADCNTCHITNLTDLHAQRGFQCAACHASTNTAITAAVQKGLGGQPVV
CADCHNAIGGFGNHAKQHDMVTLNSTTGFIAAHEEKMVYCFTCHNNTNAGYQKAINDGMAGIPQTCTSCHAAYGNQPPVA
NAGANVTTTVNKAVTLSGAASSDPDGTIVSYAWTFGDGTTGSGVSVTKTYATAGTYTVTLTVTDNAGASASATTIVTVQA
APTSSSVFADQVLSMQRLYSVTSSDSNSSDVTANFRDGNTTDRYLLQYGSSGSNYVIAMKLNRDALTATKVVLRVYVSSI
SSSRTLRIYPYQSNGTSVNTRYYTSYSTSSTGWKDIDVTSIAQQMNGYGWMKFRVTPTSNSLYVAEGAFQVQ

Sequences:

>Translated_712_residues
MKTEDGSERGRLTVFALLALFLFVPIMQPEAHALVENNCRGCHNDAQGKTADRHHALLSLGKQCLDCHQMVGPSGSQTPV
VVRDCIACHGDLIHQGRHHQLIAERGKQCLDCHQIVVDASGANTPVVVRDCSVCHATMNPKTNHNNAMADVSCAQCHNLG
VVNEHLSRTSTCYTCHSSVNVTVQQTILSAKTGVVVTCTSCHVGFDHVAQHNMVVTPADCAGCHTQGVVYEHTNRTSTCA
TCHQSTNATVQKTITDGRNNIQVSCANCHGTVNHIAQHDMAQTAAECAQCHTKSVLDEHLTRTSTCATCHSSSRVEVQNA
ITAGRAGTVVNCVTCHGQYNHPTAHTGKVSAPYADCNTCHITNLTDLHAQRGFQCAACHASTNTAITAAVQKGLGGQPVV
CADCHNAIGGFGNHAKQHDMVTLNSTTGFIAAHEEKMVYCFTCHNNTNAGYQKAINDGMAGIPQTCTSCHAAYGNQPPVA
NAGANVTTTVNKAVTLSGAASSDPDGTIVSYAWTFGDGTTGSGVSVTKTYATAGTYTVTLTVTDNAGASASATTIVTVQA
APTSSSVFADQVLSMQRLYSVTSSDSNSSDVTANFRDGNTTDRYLLQYGSSGSNYVIAMKLNRDALTATKVVLRVYVSSI
SSSRTLRIYPYQSNGTSVNTRYYTSYSTSSTGWKDIDVTSIAQQMNGYGWMKFRVTPTSNSLYVAEGAFQVQ
>Mature_712_residues
MKTEDGSERGRLTVFALLALFLFVPIMQPEAHALVENNCRGCHNDAQGKTADRHHALLSLGKQCLDCHQMVGPSGSQTPV
VVRDCIACHGDLIHQGRHHQLIAERGKQCLDCHQIVVDASGANTPVVVRDCSVCHATMNPKTNHNNAMADVSCAQCHNLG
VVNEHLSRTSTCYTCHSSVNVTVQQTILSAKTGVVVTCTSCHVGFDHVAQHNMVVTPADCAGCHTQGVVYEHTNRTSTCA
TCHQSTNATVQKTITDGRNNIQVSCANCHGTVNHIAQHDMAQTAAECAQCHTKSVLDEHLTRTSTCATCHSSSRVEVQNA
ITAGRAGTVVNCVTCHGQYNHPTAHTGKVSAPYADCNTCHITNLTDLHAQRGFQCAACHASTNTAITAAVQKGLGGQPVV
CADCHNAIGGFGNHAKQHDMVTLNSTTGFIAAHEEKMVYCFTCHNNTNAGYQKAINDGMAGIPQTCTSCHAAYGNQPPVA
NAGANVTTTVNKAVTLSGAASSDPDGTIVSYAWTFGDGTTGSGVSVTKTYATAGTYTVTLTVTDNAGASASATTIVTVQA
APTSSSVFADQVLSMQRLYSVTSSDSNSSDVTANFRDGNTTDRYLLQYGSSGSNYVIAMKLNRDALTATKVVLRVYVSSI
SSSRTLRIYPYQSNGTSVNTRYYTSYSTSSTGWKDIDVTSIAQQMNGYGWMKFRVTPTSNSLYVAEGAFQVQ

Specific function: Unknown

COG id: COG3291

COG function: function code R; FOG: PKD repeat

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PKD domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008979
- InterPro:   IPR017323
- InterPro:   IPR009003
- InterPro:   IPR022409
- InterPro:   IPR000601
- InterPro:   IPR002884 [H]

Pfam domain/function: PF01483 P_proprotein; PF00801 PKD [H]

EC number: =3.4.21.50 [H]

Molecular weight: Translated: 75579; Mature: 75579

Theoretical pI: Translated: 7.37; Mature: 7.37

Prosite motif: PS50093 PKD ; PS51008 MULTIHEME_CYTC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
5.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTEDGSERGRLTVFALLALFLFVPIMQPEAHALVENNCRGCHNDAQGKTADRHHALLSL
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHH
GKQCLDCHQMVGPSGSQTPVVVRDCIACHGDLIHQGRHHQLIAERGKQCLDCHQIVVDAS
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHCCEEEEEECC
GANTPVVVRDCSVCHATMNPKTNHNNAMADVSCAQCHNLGVVNEHLSRTSTCYTCHSSVN
CCCCCEEEEECCEEEEECCCCCCCCCCEECCHHHHHHCCCCHHHHHHCCCEEEEECCCCE
VTVQQTILSAKTGVVVTCTSCHVGFDHVAQHNMVVTPADCAGCHTQGVVYEHTNRTSTCA
EEEEHHHHHCCCCEEEEEEECCCCHHHHHCCCEEEECCCCCCCCCCCEEEECCCCCCHHH
TCHQSTNATVQKTITDGRNNIQVSCANCHGTVNHIAQHDMAQTAAECAQCHTKSVLDEHL
HHHCCCCCEEEEEECCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TRTSTCATCHSSSRVEVQNAITAGRAGTVVNCVTCHGQYNHPTAHTGKVSAPYADCNTCH
HCCCHHHCCCCCCCEEEHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEE
ITNLTDLHAQRGFQCAACHASTNTAITAAVQKGLGGQPVVCADCHNAIGGFGNHAKQHDM
ECCCHHHHHHCCCEEEEEECCCCCEEHHHHHHCCCCCCEEEECHHHHHCCCCCCCCCCCE
VTLNSTTGFIAAHEEKMVYCFTCHNNTNAGYQKAINDGMAGIPQTCTSCHAAYGNQPPVA
EEEECCCCEEEECCCCEEEEEEEECCCCCHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCC
NAGANVTTTVNKAVTLSGAASSDPDGTIVSYAWTFGDGTTGSGVSVTKTYATAGTYTVTL
CCCCCEEEEECEEEEEECCCCCCCCCCEEEEEEEECCCCCCCCEEEEEEEECCCEEEEEE
TVTDNAGASASATTIVTVQAAPTSSSVFADQVLSMQRLYSVTSSDSNSSDVTANFRDGNT
EEECCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCC
TDRYLLQYGSSGSNYVIAMKLNRDALTATKVVLRVYVSSISSSRTLRIYPYQSNGTSVNT
CCHHHEEECCCCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEE
RYYTSYSTSSTGWKDIDVTSIAQQMNGYGWMKFRVTPTSNSLYVAEGAFQVQ
EEEEEECCCCCCCCCCHHHHHHHHHCCCEEEEEEEECCCCCEEEECCCEEEC
>Mature Secondary Structure
MKTEDGSERGRLTVFALLALFLFVPIMQPEAHALVENNCRGCHNDAQGKTADRHHALLSL
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHH
GKQCLDCHQMVGPSGSQTPVVVRDCIACHGDLIHQGRHHQLIAERGKQCLDCHQIVVDAS
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHCCEEEEEECC
GANTPVVVRDCSVCHATMNPKTNHNNAMADVSCAQCHNLGVVNEHLSRTSTCYTCHSSVN
CCCCCEEEEECCEEEEECCCCCCCCCCEECCHHHHHHCCCCHHHHHHCCCEEEEECCCCE
VTVQQTILSAKTGVVVTCTSCHVGFDHVAQHNMVVTPADCAGCHTQGVVYEHTNRTSTCA
EEEEHHHHHCCCCEEEEEEECCCCHHHHHCCCEEEECCCCCCCCCCCEEEECCCCCCHHH
TCHQSTNATVQKTITDGRNNIQVSCANCHGTVNHIAQHDMAQTAAECAQCHTKSVLDEHL
HHHCCCCCEEEEEECCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TRTSTCATCHSSSRVEVQNAITAGRAGTVVNCVTCHGQYNHPTAHTGKVSAPYADCNTCH
HCCCHHHCCCCCCCEEEHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEE
ITNLTDLHAQRGFQCAACHASTNTAITAAVQKGLGGQPVVCADCHNAIGGFGNHAKQHDM
ECCCHHHHHHCCCEEEEEECCCCCEEHHHHHHCCCCCCEEEECHHHHHCCCCCCCCCCCE
VTLNSTTGFIAAHEEKMVYCFTCHNNTNAGYQKAINDGMAGIPQTCTSCHAAYGNQPPVA
EEEECCCCEEEECCCCEEEEEEEECCCCCHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCC
NAGANVTTTVNKAVTLSGAASSDPDGTIVSYAWTFGDGTTGSGVSVTKTYATAGTYTVTL
CCCCCEEEEECEEEEEECCCCCCCCCCEEEEEEEECCCCCCCCEEEEEEEECCCEEEEEE
TVTDNAGASASATTIVTVQAAPTSSSVFADQVLSMQRLYSVTSSDSNSSDVTANFRDGNT
EEECCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCC
TDRYLLQYGSSGSNYVIAMKLNRDALTATKVVLRVYVSSISSSRTLRIYPYQSNGTSVNT
CCHHHEEECCCCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEE
RYYTSYSTSSTGWKDIDVTSIAQQMNGYGWMKFRVTPTSNSLYVAEGAFQVQ
EEEEEECCCCCCCCCCHHHHHHHHHCCCEEEEEEEECCCCCEEEECCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2684982; 2492988 [H]