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The map label for this gene is corA [H]

Identifier: 78221361

GI number: 78221361

Start: 162483

End: 163436

Strand: Reverse

Name: corA [H]

Synonym: Gmet_0134

Alternate gene names: 78221361

Gene position: 163436-162483 (Counterclockwise)

Preceding gene: 78221362

Following gene: 78221360

Centisome position: 4.09

GC content: 59.43

Gene sequence:

>954_bases
ATGATCAAGGCCTACCTCCGCGCGGAGGATTCATTCAGAACGGTCTCCGTTGAGCCCGATGAGCTCGTGGACCTGGATGT
CAGCTCCCTCATCTGGCTCGACCTCCTCTCCCCCTCCACGGACGAGCTCGCCACCGTGGAGCGGAGCCTGAAGATCGAGC
TCCCGACCCGCCAGGAGTCGGAGGAGATCGAGTTCAGCTCCCGGTTCTGGGAGGACGAAAGCGGCATCGACATCAATACC
TACTTCCTGGTGCGCCAGGAGGAAAAGTTCCACAACGAGACCGTCTCCTTCATTCTCCGGGGGAAGTTCGTGGTCACCAT
CCGCTTCAGCGACCACCGGATCTTCACCGAGTTTTCCCGCAAGCTGCGCCTCAGCCCCCGTTCGTTTCGGGATGGGGCCG
ATATCCTGTCGGGGATCCTCGCCATGCGGGTCGACATGGACGCCGACACCCTGGAGGCGCTCTCCCGGGGGATCGCCAGC
CTTGGCCGGCGCGGTCCCCAGACCTTCGAGAACCCGACCGAGTACCTCTCCCACATCACCGACTACGAAGACATCAACAT
CACCATCCGGGAGAACCTGACTGACAAGCACCGGGTCCTGTCGTCGCTCCTGAAGAGCGCTTCCATCTCCGAGAACCTCA
AGAAGGAGTTCAGCATGATGATGAAGGACGTGAACTCCCTCGTCATCTCGGCCAACTTCAACTTCGAGCGCCTCGACTAC
ATCCAGAACCTCTTCCTCAACCACCTGAGTGTTGAGCAGAACAAGGTCATCAAGATCTTCACCGTCATGTCGGTGATCTT
CCTGCCGCCCACCATGATCGCCAGCATCTACGGCATGAACTACAAACACATGCCCGAACTGGAATGGGTCTTCGGCTACC
CCTTCGCCCTCACGCTGATCATCCTCTCGGCCGTGCTCCCCCTCTACGTCTTCAAGAAGAAGGGGTGGCTGTAA

Upstream 100 bases:

>100_bases
GACGTTATGGGGGAAATGTTCCCTTGACCGTCCTTCCCCTTCCATCTACAATTTTTTCGATGCGCCAACGGCGCGATTTT
GAACCGGGAAATGGTGTTCC

Downstream 100 bases:

>100_bases
CATGGCCCGCAAGCCCTCCTCCCCGAAGAGAACCGCCCCCGAAACAGCGGCGGGCGGGGAGTGGTCGGTCTGCGACCTGG
CCGCCCCCGAGCTCTACCTG

Product: magnesium/cobalt transporter CorA

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MIKAYLRAEDSFRTVSVEPDELVDLDVSSLIWLDLLSPSTDELATVERSLKIELPTRQESEEIEFSSRFWEDESGIDINT
YFLVRQEEKFHNETVSFILRGKFVVTIRFSDHRIFTEFSRKLRLSPRSFRDGADILSGILAMRVDMDADTLEALSRGIAS
LGRRGPQTFENPTEYLSHITDYEDINITIRENLTDKHRVLSSLLKSASISENLKKEFSMMMKDVNSLVISANFNFERLDY
IQNLFLNHLSVEQNKVIKIFTVMSVIFLPPTMIASIYGMNYKHMPELEWVFGYPFALTLIILSAVLPLYVFKKKGWL

Sequences:

>Translated_317_residues
MIKAYLRAEDSFRTVSVEPDELVDLDVSSLIWLDLLSPSTDELATVERSLKIELPTRQESEEIEFSSRFWEDESGIDINT
YFLVRQEEKFHNETVSFILRGKFVVTIRFSDHRIFTEFSRKLRLSPRSFRDGADILSGILAMRVDMDADTLEALSRGIAS
LGRRGPQTFENPTEYLSHITDYEDINITIRENLTDKHRVLSSLLKSASISENLKKEFSMMMKDVNSLVISANFNFERLDY
IQNLFLNHLSVEQNKVIKIFTVMSVIFLPPTMIASIYGMNYKHMPELEWVFGYPFALTLIILSAVLPLYVFKKKGWL
>Mature_317_residues
MIKAYLRAEDSFRTVSVEPDELVDLDVSSLIWLDLLSPSTDELATVERSLKIELPTRQESEEIEFSSRFWEDESGIDINT
YFLVRQEEKFHNETVSFILRGKFVVTIRFSDHRIFTEFSRKLRLSPRSFRDGADILSGILAMRVDMDADTLEALSRGIAS
LGRRGPQTFENPTEYLSHITDYEDINITIRENLTDKHRVLSSLLKSASISENLKKEFSMMMKDVNSLVISANFNFERLDY
IQNLFLNHLSVEQNKVIKIFTVMSVIFLPPTMIASIYGMNYKHMPELEWVFGYPFALTLIILSAVLPLYVFKKKGWL

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=293, Percent_Identity=34.4709897610922, Blast_Score=179, Evalue=2e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 36722; Mature: 36722

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS00041 HTH_ARAC_FAMILY_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKAYLRAEDSFRTVSVEPDELVDLDVSSLIWLDLLSPSTDELATVERSLKIELPTRQES
CCEEEEECCCCCEEEECCCHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHEEEECCCCCCC
EEIEFSSRFWEDESGIDINTYFLVRQEEKFHNETVSFILRGKFVVTIRFSDHRIFTEFSR
HHHHHHHHCCCCCCCCEEEEEEEEECHHHHHHHHHHHEEECEEEEEEEECCCHHHHHHHH
KLRLSPRSFRDGADILSGILAMRVDMDADTLEALSRGIASLGRRGPQTFENPTEYLSHIT
HHCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCC
DYEDINITIRENLTDKHRVLSSLLKSASISENLKKEFSMMMKDVNSLVISANFNFERLDY
CCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHH
IQNLFLNHLSVEQNKVIKIFTVMSVIFLPPTMIASIYGMNYKHMPELEWVFGYPFALTLI
HHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCEEECCHHHHHHH
ILSAVLPLYVFKKKGWL
HHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MIKAYLRAEDSFRTVSVEPDELVDLDVSSLIWLDLLSPSTDELATVERSLKIELPTRQES
CCEEEEECCCCCEEEECCCHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHEEEECCCCCCC
EEIEFSSRFWEDESGIDINTYFLVRQEEKFHNETVSFILRGKFVVTIRFSDHRIFTEFSR
HHHHHHHHCCCCCCCCEEEEEEEEECHHHHHHHHHHHEEECEEEEEEEECCCHHHHHHHH
KLRLSPRSFRDGADILSGILAMRVDMDADTLEALSRGIASLGRRGPQTFENPTEYLSHIT
HHCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCC
DYEDINITIRENLTDKHRVLSSLLKSASISENLKKEFSMMMKDVNSLVISANFNFERLDY
CCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHH
IQNLFLNHLSVEQNKVIKIFTVMSVIFLPPTMIASIYGMNYKHMPELEWVFGYPFALTLI
HHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCEEECCHHHHHHH
ILSAVLPLYVFKKKGWL
HHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12810954 [H]