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The map label for this gene is glmM [H]

Identifier: 78221362

GI number: 78221362

Start: 163535

End: 164944

Strand: Reverse

Name: glmM [H]

Synonym: Gmet_0135

Alternate gene names: 78221362

Gene position: 164944-163535 (Counterclockwise)

Preceding gene: 78221366

Following gene: 78221361

Centisome position: 4.13

GC content: 67.59

Gene sequence:

>1410_bases
GTGCAGATAAAGTTCGGAACTGACGGCTGGCGCGGGGTTATTGCCCGGGATTTCACCTTCGACAACCTCTCCCGGGTGGC
CCAGGCTACCATGGAGTACCTCATCCGCGAAGGACTCGCTCCCCGGGGGCTCGTGATCGGCTACGACCGCCGCTTCCTTT
CCCGGGAGTTTGCCGAGCGGGTGGCGGAGATCGCCGCCGGCAACGGCATCCGGGTCTGGCTCACCGCAGGCTACGCCCCG
ACCCCGGCGGTCTCCTGGGCGGTCCACGAGCTGGGGGCCGGCGGCGGCGTCATGATCACCGCAAGCCACAACCCCCCCGC
TTACAACGGCTTCAAGGTGAAGGAGTCCTTTGGCGGCTCGGCCCGCCCCTCCACCACGAAGATCCTGGAGGAGATGGTGG
CCGCCAACGACGCCGCCGGCCGCGAGATCAAGGCCCGCCCCCTGGCCGAAGCCCTGGCCGACGGGAGTGTCGCCACCTTT
GACCCCAAAGGGGGGTATTTCCGGCAGCTGGCCCGTTATGTGGATCTGGAGGCGATCCGGAAGGCGAACCTCCCCGTGGT
CGTGGACCCTATGTTTGGTGCCGGCGCCGGCTTCGTGCCGGAGCTCCTCCCCGGGGTCCGGGAGATTCACGGCGACGAGA
ACCCTTCCTTCGGGGGACAGCCTCCGGAGCCCACTGAAGAGCACCTGACGGAGCTGGCGGCCCTGGTGGCAAGCGGCCGG
TACCGCATCGGCCTGGCCCTGGACGGCGACGCCGACCGGATCGGCGCCGTGGACGAGACCGGCGAGTTCTTCTCCTCCCA
CCGGATCTTCACGGTGATCCTCCGGCACCTGGTGGAGCGCAAGGGGCTCACCGGCGGGGTGGTGAAGACTGTCTCCACCA
CCCGCATGGTGGATCTTCTGGCCGAGAAGTTCGGCCTCCCCCTCCACGAGACCCCCATCGGCTTCAAGCATATCTGCGAG
CTGATGCTCGACCACGACATCCTCATGGGGGGCGAGGAGTCGGGGGGGCTCGGCGTCAAGGGGCACATCCCGGAGCGGGA
CGGCATCCTCATGGGGCTCCTCCTCCTGGAGGCCATGGCCGTGAGCGGCAAGGGAGTCCGGCAGCTTCTCGACGAGACCA
TGGACGAGATCGGCCGCTTTTGCTACCGCCGCATTGACCTCCCCATCGCCGACGCCGCCAAGGAGCTCCTCATCGCCCGG
CTGAAGCAGGGAGGGATTGCCTCTATTGCGGGTCGTAACGTGGCACGGGAGAATTTCCGCGACGGCTTCAAGTTCATTTT
TGAGGATGGCTCCTGGCTCCTGATCCGTCCGTCGGGGACCGAGCCGGTGCTCAGGCTCTACAGCGAGGCCGGCGATGCGC
AGACGGTGGAGGAACTCCTGGCCGCGGCCCGGGAGATCGCCGGGCTGTGA

Upstream 100 bases:

>100_bases
GAAAGAAATAAACAAAAGGTTGACTTGACGGGCGATAGTGCGGAAAATTGTCTAGTTTTACGTACGATTACCCATGAACT
GACATTCAGGAGGAGAGACG

Downstream 100 bases:

>100_bases
CGTTATGGGGGAAATGTTCCCTTGACCGTCCTTCCCCTTCCATCTACAATTTTTTCGATGCGCCAACGGCGCGATTTTGA
ACCGGGAAATGGTGTTCCAT

Product: phosphoglucomutase/phosphomannomutase alpha/beta/subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 469; Mature: 469

Protein sequence:

>469_residues
MQIKFGTDGWRGVIARDFTFDNLSRVAQATMEYLIREGLAPRGLVIGYDRRFLSREFAERVAEIAAGNGIRVWLTAGYAP
TPAVSWAVHELGAGGGVMITASHNPPAYNGFKVKESFGGSARPSTTKILEEMVAANDAAGREIKARPLAEALADGSVATF
DPKGGYFRQLARYVDLEAIRKANLPVVVDPMFGAGAGFVPELLPGVREIHGDENPSFGGQPPEPTEEHLTELAALVASGR
YRIGLALDGDADRIGAVDETGEFFSSHRIFTVILRHLVERKGLTGGVVKTVSTTRMVDLLAEKFGLPLHETPIGFKHICE
LMLDHDILMGGEESGGLGVKGHIPERDGILMGLLLLEAMAVSGKGVRQLLDETMDEIGRFCYRRIDLPIADAAKELLIAR
LKQGGIASIAGRNVARENFRDGFKFIFEDGSWLLIRPSGTEPVLRLYSEAGDAQTVEELLAAAREIAGL

Sequences:

>Translated_469_residues
MQIKFGTDGWRGVIARDFTFDNLSRVAQATMEYLIREGLAPRGLVIGYDRRFLSREFAERVAEIAAGNGIRVWLTAGYAP
TPAVSWAVHELGAGGGVMITASHNPPAYNGFKVKESFGGSARPSTTKILEEMVAANDAAGREIKARPLAEALADGSVATF
DPKGGYFRQLARYVDLEAIRKANLPVVVDPMFGAGAGFVPELLPGVREIHGDENPSFGGQPPEPTEEHLTELAALVASGR
YRIGLALDGDADRIGAVDETGEFFSSHRIFTVILRHLVERKGLTGGVVKTVSTTRMVDLLAEKFGLPLHETPIGFKHICE
LMLDHDILMGGEESGGLGVKGHIPERDGILMGLLLLEAMAVSGKGVRQLLDETMDEIGRFCYRRIDLPIADAAKELLIAR
LKQGGIASIAGRNVARENFRDGFKFIFEDGSWLLIRPSGTEPVLRLYSEAGDAQTVEELLAAAREIAGL
>Mature_469_residues
MQIKFGTDGWRGVIARDFTFDNLSRVAQATMEYLIREGLAPRGLVIGYDRRFLSREFAERVAEIAAGNGIRVWLTAGYAP
TPAVSWAVHELGAGGGVMITASHNPPAYNGFKVKESFGGSARPSTTKILEEMVAANDAAGREIKARPLAEALADGSVATF
DPKGGYFRQLARYVDLEAIRKANLPVVVDPMFGAGAGFVPELLPGVREIHGDENPSFGGQPPEPTEEHLTELAALVASGR
YRIGLALDGDADRIGAVDETGEFFSSHRIFTVILRHLVERKGLTGGVVKTVSTTRMVDLLAEKFGLPLHETPIGFKHICE
LMLDHDILMGGEESGGLGVKGHIPERDGILMGLLLLEAMAVSGKGVRQLLDETMDEIGRFCYRRIDLPIADAAKELLIAR
LKQGGIASIAGRNVARENFRDGFKFIFEDGSWLLIRPSGTEPVLRLYSEAGDAQTVEELLAAAREIAGL

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate [H]

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI133922562, Length=489, Percent_Identity=26.7893660531697, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI21361621, Length=468, Percent_Identity=27.7777777777778, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI290463102, Length=473, Percent_Identity=27.2727272727273, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI31377548, Length=537, Percent_Identity=26.2569832402235, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI63055049, Length=528, Percent_Identity=25.5681818181818, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI290463104, Length=305, Percent_Identity=26.2295081967213, Blast_Score=83, Evalue=5e-16,
Organism=Escherichia coli, GI1786904, Length=501, Percent_Identity=30.5389221556886, Blast_Score=151, Evalue=1e-37,
Organism=Escherichia coli, GI1789566, Length=465, Percent_Identity=26.8817204301075, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1788361, Length=459, Percent_Identity=24.1830065359477, Blast_Score=85, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17535441, Length=493, Percent_Identity=27.3833671399594, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI71993870, Length=515, Percent_Identity=26.7961165048544, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71993878, Length=283, Percent_Identity=30.0353356890459, Blast_Score=78, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6323752, Length=430, Percent_Identity=26.9767441860465, Blast_Score=107, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6322722, Length=408, Percent_Identity=27.9411764705882, Blast_Score=104, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6323934, Length=409, Percent_Identity=25.9168704156479, Blast_Score=74, Evalue=4e-14,
Organism=Drosophila melanogaster, GI17864244, Length=521, Percent_Identity=28.0230326295585, Blast_Score=150, Evalue=2e-36,
Organism=Drosophila melanogaster, GI20129809, Length=524, Percent_Identity=26.7175572519084, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24651977, Length=386, Percent_Identity=27.979274611399, Blast_Score=112, Evalue=8e-25,
Organism=Drosophila melanogaster, GI24653722, Length=420, Percent_Identity=24.2857142857143, Blast_Score=76, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.10 [H]

Molecular weight: Translated: 50706; Mature: 50706

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIKFGTDGWRGVIARDFTFDNLSRVAQATMEYLIREGLAPRGLVIGYDRRFLSREFAER
CEEECCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHH
VAEIAAGNGIRVWLTAGYAPTPAVSWAVHELGAGGGVMITASHNPPAYNGFKVKESFGGS
HHHHHCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCEEEHHCCCCC
ARPSTTKILEEMVAANDAAGREIKARPLAEALADGSVATFDPKGGYFRQLARYVDLEAIR
CCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHH
KANLPVVVDPMFGAGAGFVPELLPGVREIHGDENPSFGGQPPEPTEEHLTELAALVASGR
HCCCCEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
YRIGLALDGDADRIGAVDETGEFFSSHRIFTVILRHLVERKGLTGGVVKTVSTTRMVDLL
EEEEEEECCCCHHCCCCCHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
AEKFGLPLHETPIGFKHICELMLDHDILMGGEESGGLGVKGHIPERDGILMGLLLLEAMA
HHHHCCCCCCCCCCHHHHHHHHHCCHHEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
VSGKGVRQLLDETMDEIGRFCYRRIDLPIADAAKELLIARLKQGGIASIAGRNVARENFR
HCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHH
DGFKFIFEDGSWLLIRPSGTEPVLRLYSEAGDAQTVEELLAAAREIAGL
HHHHEEEECCCEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQIKFGTDGWRGVIARDFTFDNLSRVAQATMEYLIREGLAPRGLVIGYDRRFLSREFAER
CEEECCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHH
VAEIAAGNGIRVWLTAGYAPTPAVSWAVHELGAGGGVMITASHNPPAYNGFKVKESFGGS
HHHHHCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCEEEHHCCCCC
ARPSTTKILEEMVAANDAAGREIKARPLAEALADGSVATFDPKGGYFRQLARYVDLEAIR
CCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHH
KANLPVVVDPMFGAGAGFVPELLPGVREIHGDENPSFGGQPPEPTEEHLTELAALVASGR
HCCCCEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
YRIGLALDGDADRIGAVDETGEFFSSHRIFTVILRHLVERKGLTGGVVKTVSTTRMVDLL
EEEEEEECCCCHHCCCCCHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
AEKFGLPLHETPIGFKHICELMLDHDILMGGEESGGLGVKGHIPERDGILMGLLLLEAMA
HHHHCCCCCCCCCCHHHHHHHHHCCHHEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
VSGKGVRQLLDETMDEIGRFCYRRIDLPIADAAKELLIARLKQGGIASIAGRNVARENFR
HCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHH
DGFKFIFEDGSWLLIRPSGTEPVLRLYSEAGDAQTVEELLAAAREIAGL
HHHHEEEECCCEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]