Click here to switch to the map view.

The map label for this gene is hypB [H]

Identifier: 78221347

GI number: 78221347

Start: 146616

End: 147350

Strand: Reverse

Name: hypB [H]

Synonym: Gmet_0120

Alternate gene names: 78221347

Gene position: 147350-146616 (Counterclockwise)

Preceding gene: 78221355

Following gene: 78221346

Centisome position: 3.69

GC content: 63.4

Gene sequence:

>735_bases
ATGTGCACCACCTGCGGTTGCGAAACCGATACCCATCATCACCATCACCACCATCATCATGGCGAAGGGAAAGAAGCCCG
CAAGATCGCCGTTGAACTGGACATCCTCGCCCGCAACAACCGCTTTGCCGCCGAGAACCGGGCACTCTTCGCCGCCAAGG
GGATCTTCGCCCTCAATTTCGTGAGTTCACCCGGTTCGGGGAAGACCACCACCCTGGAGCGGACGTTAAAGGACTTGGCC
GGCCGGTACCGCTGCGCCGTCATCGAGGGGGACCAGCAGACCGACAATGACGCCGTCCGCATCGCCGCCACCGGCGTGCC
GGTGAAGCAGATCAACACCGGCGCCGGGTGCCACCTGGACGCCCACATGGTGGGCCACGCCGTTGAGGAATTCGACCTGG
ACGCCCTCGATCTCCTCCTGGTGGAGAACGTGGGGAACCTGGTCTGCCCCGCCTCCTTCGACCTGGGGGAGCATCACAAG
GTGGTGGTCCTGTCGGTGACCGAGGGGGAGGACAAGCCCCTTAAGTACCCGAATATGTTCCACGCCGCCGACGTGATGCT
CCTCAACAAGGTGGATCTCCTCCCCTACGTGGACTTCGACGTGGAGAAGTGCAAGGAAATGGCCCGCCGCGTGAGCCCCG
ACATCGCCATCTTCGAGATCTCCAGCCGCACCGGAGAGGGGATGGATGCCTGGTACGGCTGGCTTGCCGGCCGCATCGCC
GCCGTGAAGGGATAA

Upstream 100 bases:

>100_bases
CTTGACCTTTTGGGTCGAATACTATAGGCTCGTCGGTAACTAGCTGAGAGAAATGATGTTTTATCTTGCGAAGCAGCCAT
GGACAGGAGGAGTCTCGATC

Downstream 100 bases:

>100_bases
CGCCGCGTTTCGTCCCATGACCGATGCCAGGCGCACCAGGATAACCATTGAGGGGATTGTCCAGGGGGTCGGCTTCCGCC
CCTTCGTCTTCCGCCTCGCG

Product: hydrogenase accessory protein HypB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
MCTTCGCETDTHHHHHHHHHGEGKEARKIAVELDILARNNRFAAENRALFAAKGIFALNFVSSPGSGKTTTLERTLKDLA
GRYRCAVIEGDQQTDNDAVRIAATGVPVKQINTGAGCHLDAHMVGHAVEEFDLDALDLLLVENVGNLVCPASFDLGEHHK
VVVLSVTEGEDKPLKYPNMFHAADVMLLNKVDLLPYVDFDVEKCKEMARRVSPDIAIFEISSRTGEGMDAWYGWLAGRIA
AVKG

Sequences:

>Translated_244_residues
MCTTCGCETDTHHHHHHHHHGEGKEARKIAVELDILARNNRFAAENRALFAAKGIFALNFVSSPGSGKTTTLERTLKDLA
GRYRCAVIEGDQQTDNDAVRIAATGVPVKQINTGAGCHLDAHMVGHAVEEFDLDALDLLLVENVGNLVCPASFDLGEHHK
VVVLSVTEGEDKPLKYPNMFHAADVMLLNKVDLLPYVDFDVEKCKEMARRVSPDIAIFEISSRTGEGMDAWYGWLAGRIA
AVKG
>Mature_244_residues
MCTTCGCETDTHHHHHHHHHGEGKEARKIAVELDILARNNRFAAENRALFAAKGIFALNFVSSPGSGKTTTLERTLKDLA
GRYRCAVIEGDQQTDNDAVRIAATGVPVKQINTGAGCHLDAHMVGHAVEEFDLDALDLLLVENVGNLVCPASFDLGEHHK
VVVLSVTEGEDKPLKYPNMFHAADVMLLNKVDLLPYVDFDVEKCKEMARRVSPDIAIFEISSRTGEGMDAWYGWLAGRIA
AVKG

Specific function: Could be involved in nickel binding and accumulation [H]

COG id: COG0378

COG function: function code OK; Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypB/hupM family [H]

Homologues:

Organism=Escherichia coli, GI1789082, Length=284, Percent_Identity=53.169014084507, Blast_Score=284, Evalue=3e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003495
- InterPro:   IPR004392
- InterPro:   IPR012202 [H]

Pfam domain/function: PF02492 cobW [H]

EC number: NA

Molecular weight: Translated: 26721; Mature: 26721

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCTTCGCETDTHHHHHHHHHGEGKEARKIAVELDILARNNRFAAENRALFAAKGIFALNF
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCEEEEECCEEEEEE
VSSPGSGKTTTLERTLKDLAGRYRCAVIEGDQQTDNDAVRIAATGVPVKQINTGAGCHLD
ECCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCEEEEEECCCCHHHCCCCCCCEEH
AHMVGHAVEEFDLDALDLLLVENVGNLVCPASFDLGEHHKVVVLSVTEGEDKPLKYPNMF
HHHHHHHHHHCCCCHHHHHHHHCCCCEECCCCCCCCCCCEEEEEEEECCCCCCCCCCCCH
HAADVMLLNKVDLLPYVDFDVEKCKEMARRVSPDIAIFEISSRTGEGMDAWYGWLAGRIA
HHHHHHEEECCCCCEECCCCHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHEEE
AVKG
ECCC
>Mature Secondary Structure
MCTTCGCETDTHHHHHHHHHGEGKEARKIAVELDILARNNRFAAENRALFAAKGIFALNF
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCEEEEECCEEEEEE
VSSPGSGKTTTLERTLKDLAGRYRCAVIEGDQQTDNDAVRIAATGVPVKQINTGAGCHLD
ECCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCEEEEEECCCCHHHCCCCCCCEEH
AHMVGHAVEEFDLDALDLLLVENVGNLVCPASFDLGEHHKVVVLSVTEGEDKPLKYPNMF
HHHHHHHHHHCCCCHHHHHHHHCCCCEECCCCCCCCCCCEEEEEEEECCCCCCCCCCCCH
HAADVMLLNKVDLLPYVDFDVEKCKEMARRVSPDIAIFEISSRTGEGMDAWYGWLAGRIA
HHHHHHEEECCCCCEECCCCHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHEEE
AVKG
ECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8486288 [H]