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The map label for this gene is groES

Identifier: 78221256

GI number: 78221256

Start: 34354

End: 34641

Strand: Direct

Name: groES

Synonym: Gmet_0028

Alternate gene names: 78221256

Gene position: 34354-34641 (Clockwise)

Preceding gene: 78221255

Following gene: 78221257

Centisome position: 0.86

GC content: 59.03

Gene sequence:

>288_bases
ATGAAACTCAGACCGTTGCAGGACCGCATCCTCGTGAAGAGAATCGAGGAGGAGCAAGTTACCGCCGGAGGGATCTTCAT
CCCCGACACCGCCAAGGAGAAGCCCCAGCGCGGCGAGATCGTGGCCGTCGGCAATGGCAAGAAGACCGAAGACGGCAAGG
TGATCCCCATCGACCTGAAGGTGGGCGACAAGGTGCTCTTCGGCAAGTACGCCGGCACCGACATCAAGGTCGAGGGCGAA
GACTTCCTGATTATGAGGGAAGACGACATCCTCGGCGTCATCGAATAG

Upstream 100 bases:

>100_bases
TGACTATAGTTACTTCGCGTTAGCACTCAGCTGTATCGAGTGCTAATTTTTTTCGATGAAATCACGTGAGCATACTCATG
AAAGAAAGGAGAAGCTGCAG

Downstream 100 bases:

>100_bases
AGTGGCCGGCTTCGCCGAAGGTCCATCCGGAGCCTTTGGCCGTGCCATGAAACAGCATAGATAACAACATACGAAGACGA
AGATTAAATAGGGAGGAACG

Product: co-chaperonin GroES

Products: NA

Alternate protein names: GroES protein; Protein Cpn10

Number of amino acids: Translated: 95; Mature: 95

Protein sequence:

>95_residues
MKLRPLQDRILVKRIEEEQVTAGGIFIPDTAKEKPQRGEIVAVGNGKKTEDGKVIPIDLKVGDKVLFGKYAGTDIKVEGE
DFLIMREDDILGVIE

Sequences:

>Translated_95_residues
MKLRPLQDRILVKRIEEEQVTAGGIFIPDTAKEKPQRGEIVAVGNGKKTEDGKVIPIDLKVGDKVLFGKYAGTDIKVEGE
DFLIMREDDILGVIE
>Mature_95_residues
MKLRPLQDRILVKRIEEEQVTAGGIFIPDTAKEKPQRGEIVAVGNGKKTEDGKVIPIDLKVGDKVLFGKYAGTDIKVEGE
DFLIMREDDILGVIE

Specific function: Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter

COG id: COG0234

COG function: function code O; Co-chaperonin GroES (HSP10)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GroES chaperonin family

Homologues:

Organism=Homo sapiens, GI4504523, Length=91, Percent_Identity=43.956043956044, Blast_Score=71, Evalue=2e-13,
Organism=Homo sapiens, GI169210012, Length=91, Percent_Identity=41.7582417582418, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1790585, Length=96, Percent_Identity=48.9583333333333, Blast_Score=92, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17555568, Length=93, Percent_Identity=38.7096774193548, Blast_Score=78, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6324594, Length=92, Percent_Identity=42.3913043478261, Blast_Score=66, Evalue=9e-13,
Organism=Drosophila melanogaster, GI21356029, Length=97, Percent_Identity=40.2061855670103, Blast_Score=67, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21358317, Length=96, Percent_Identity=38.5416666666667, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: 980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5720 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 1274 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): CH10_GEOMG (Q39ZP6)

Other databases:

- EMBL:   CP000148
- RefSeq:   YP_383003.1
- ProteinModelPortal:   Q39ZP6
- SMR:   Q39ZP6
- STRING:   Q39ZP6
- GeneID:   3739605
- GenomeReviews:   CP000148_GR
- KEGG:   gme:Gmet_0028
- NMPDR:   fig|269799.3.peg.92
- eggNOG:   COG0234
- HOGENOM:   HBG703377
- OMA:   RIVIQQV
- PhylomeDB:   Q39ZP6
- ProtClustDB:   PRK00364
- BioCyc:   GMET269799:GMET_0028-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00580
- InterPro:   IPR020818
- InterPro:   IPR018369
- InterPro:   IPR011032
- Gene3D:   G3DSA:2.30.33.40
- PANTHER:   PTHR10772
- PRINTS:   PR00297
- SMART:   SM00883

Pfam domain/function: PF00166 Cpn10; SSF50129 GroES_like

EC number: NA

Molecular weight: Translated: 10535; Mature: 10535

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS00681 CHAPERONINS_CPN10

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLRPLQDRILVKRIEEEQVTAGGIFIPDTAKEKPQRGEIVAVGNGKKTEDGKVIPIDLK
CCCCCCCHHHHHHHCCCCCEEECCEECCCCCCCCCCCCCEEEECCCCCCCCCCEEEEEEC
VGDKVLFGKYAGTDIKVEGEDFLIMREDDILGVIE
CCCEEEEEEECCCEEEECCCCEEEEECCCEEEEEC
>Mature Secondary Structure
MKLRPLQDRILVKRIEEEQVTAGGIFIPDTAKEKPQRGEIVAVGNGKKTEDGKVIPIDLK
CCCCCCCHHHHHHHCCCCCEEECCEECCCCCCCCCCCCCEEEECCCCCCCCCCEEEEEEC
VGDKVLFGKYAGTDIKVEGEDFLIMREDDILGVIE
CCCEEEEEEECCCEEEECCCCEEEEECCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA