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The map label for this gene is map [H]

Identifier: 78189786

GI number: 78189786

Start: 2348495

End: 2349277

Strand: Reverse

Name: map [H]

Synonym: Cag_1830

Alternate gene names: 78189786

Gene position: 2349277-2348495 (Counterclockwise)

Preceding gene: 78189787

Following gene: 78189785

Centisome position: 91.34

GC content: 42.4

Gene sequence:

>783_bases
ATGATTACCATTAAAAGCGACCGTGAAATTGAGCTAATGCGCGAAGCAGGTGCTTTAGTTTCGCAAGTACTTGACCTGAT
AGAGCATACGGTTCAAGCTGGAATGACCACAAAGCAGTTAGACGTTTTAGCCGAAGAGTATATACGTTCTCACAATGCAG
TTCCAAGCTTTTTGAACTATGTTCCTAAAAGTGATCCACATGTAACGCCATATCCAGCAACGCTCTGTGTTTCTATTAAT
GAAGAGGTGGTTCATGGAGTGCCAAGCAAAAAACGTGTGATTAAAGAAGGGGATATTGTTTCAGTTGATTGTGGGGTTTA
TAAAGGTGGCTACCATGGTGATTCAGCTCGAACCTACATTATAGGTTCAGTTGATTGTAAGGTTCAGGAATTGGTAGATG
TAACACGAGAGTCGTTAGTTAAGGGTATTGCAATGGCTGTTGATGGTAATCGGTTGCACGATATTTCCTCGGCAATTGAA
ACCTACGCACGCTCATTTGGCTTTAGTGTTATTGAGAATATGGTTGGGCATGGCATTGGTAGCGAATTGCATGAAGATCC
ACCAGTACCAAACTTTGGTCGTCCGCATACTGGCGCTAAGTTACGTTCAGGTATGACTCTTGCCATTGAGCCAATGATTG
CAATGGGGCGTTCAAAAAAAGCTGTAAGCCGTAGAGGTGGTTGGGTAGCTGTTACTGAAGACGGAAAACCCTCAGCCCAT
TTTGAGCATACCATTGTTGTTCGTCCAAAGAAAGCTGAAATTTTAACGATCAGTAAAAATTAA

Upstream 100 bases:

>100_bases
ATACGTTACAGCAAGTTGAAAGCCATCTCTTAATGCGCCATTACGATGGTTTTATGAAGTCGGGGAAAACCCGTGGTCGT
CAAGGGAGATAGTACACTTC

Downstream 100 bases:

>100_bases
GCGGCATCTTATTAGCTGCCATGTATAAGTAGTTGTAAACGAGGAGAAAGACGTTGGCGAAAGAAGAATCTATTGAAATT
GAAGGTGTTATTGTTGATGC

Product: peptidase M24A

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MITIKSDREIELMREAGALVSQVLDLIEHTVQAGMTTKQLDVLAEEYIRSHNAVPSFLNYVPKSDPHVTPYPATLCVSIN
EEVVHGVPSKKRVIKEGDIVSVDCGVYKGGYHGDSARTYIIGSVDCKVQELVDVTRESLVKGIAMAVDGNRLHDISSAIE
TYARSFGFSVIENMVGHGIGSELHEDPPVPNFGRPHTGAKLRSGMTLAIEPMIAMGRSKKAVSRRGGWVAVTEDGKPSAH
FEHTIVVRPKKAEILTISKN

Sequences:

>Translated_260_residues
MITIKSDREIELMREAGALVSQVLDLIEHTVQAGMTTKQLDVLAEEYIRSHNAVPSFLNYVPKSDPHVTPYPATLCVSIN
EEVVHGVPSKKRVIKEGDIVSVDCGVYKGGYHGDSARTYIIGSVDCKVQELVDVTRESLVKGIAMAVDGNRLHDISSAIE
TYARSFGFSVIENMVGHGIGSELHEDPPVPNFGRPHTGAKLRSGMTLAIEPMIAMGRSKKAVSRRGGWVAVTEDGKPSAH
FEHTIVVRPKKAEILTISKN
>Mature_260_residues
MITIKSDREIELMREAGALVSQVLDLIEHTVQAGMTTKQLDVLAEEYIRSHNAVPSFLNYVPKSDPHVTPYPATLCVSIN
EEVVHGVPSKKRVIKEGDIVSVDCGVYKGGYHGDSARTYIIGSVDCKVQELVDVTRESLVKGIAMAVDGNRLHDISSAIE
TYARSFGFSVIENMVGHGIGSELHEDPPVPNFGRPHTGAKLRSGMTLAIEPMIAMGRSKKAVSRRGGWVAVTEDGKPSAH
FEHTIVVRPKKAEILTISKN

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI164420681, Length=255, Percent_Identity=37.2549019607843, Blast_Score=171, Evalue=4e-43,
Organism=Homo sapiens, GI40385867, Length=255, Percent_Identity=34.1176470588235, Blast_Score=151, Evalue=6e-37,
Organism=Escherichia coli, GI1786364, Length=260, Percent_Identity=39.2307692307692, Blast_Score=191, Evalue=5e-50,
Organism=Escherichia coli, GI1788728, Length=259, Percent_Identity=24.3243243243243, Blast_Score=61, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI71996291, Length=257, Percent_Identity=33.0739299610895, Blast_Score=147, Evalue=5e-36,
Organism=Saccharomyces cerevisiae, GI6323273, Length=256, Percent_Identity=35.9375, Blast_Score=159, Evalue=5e-40,
Organism=Drosophila melanogaster, GI21355531, Length=255, Percent_Identity=38.0392156862745, Blast_Score=169, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24583427, Length=253, Percent_Identity=35.5731225296443, Blast_Score=158, Evalue=4e-39,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 28325; Mature: 28325

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITIKSDREIELMREAGALVSQVLDLIEHTVQAGMTTKQLDVLAEEYIRSHNAVPSFLNY
CEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHH
VPKSDPHVTPYPATLCVSINEEVVHGVPSKKRVIKEGDIVSVDCGVYKGGYHGDSARTYI
CCCCCCCCCCCCCEEEEECCHHHHHCCCCHHHHHCCCCEEEEECCEECCCCCCCCCCEEE
IGSVDCKVQELVDVTRESLVKGIAMAVDGNRLHDISSAIETYARSFGFSVIENMVGHGIG
EEECCCHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHCHHHHHHHHCCCCC
SELHEDPPVPNFGRPHTGAKLRSGMTLAIEPMIAMGRSKKAVSRRGGWVAVTEDGKPSAH
CHHHCCCCCCCCCCCCCCHHHHCCCEEEECHHHHCCCCHHHHHHCCCEEEEECCCCCCCC
FEHTIVVRPKKAEILTISKN
CCEEEEECCCCCEEEEEECC
>Mature Secondary Structure
MITIKSDREIELMREAGALVSQVLDLIEHTVQAGMTTKQLDVLAEEYIRSHNAVPSFLNY
CEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHH
VPKSDPHVTPYPATLCVSINEEVVHGVPSKKRVIKEGDIVSVDCGVYKGGYHGDSARTYI
CCCCCCCCCCCCCEEEEECCHHHHHCCCCHHHHHCCCCEEEEECCEECCCCCCCCCCEEE
IGSVDCKVQELVDVTRESLVKGIAMAVDGNRLHDISSAIETYARSFGFSVIENMVGHGIG
EEECCCHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHCHHHHHHHHCCCCC
SELHEDPPVPNFGRPHTGAKLRSGMTLAIEPMIAMGRSKKAVSRRGGWVAVTEDGKPSAH
CHHHCCCCCCCCCCCCCCHHHHCCCEEEECHHHHCCCCHHHHHHCCCEEEEECCCCCCCC
FEHTIVVRPKKAEILTISKN
CCEEEEECCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]