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The map label for this gene is 78189375

Identifier: 78189375

GI number: 78189375

Start: 1880924

End: 1882228

Strand: Reverse

Name: 78189375

Synonym: Cag_1412

Alternate gene names: NA

Gene position: 1882228-1880924 (Counterclockwise)

Preceding gene: 78189376

Following gene: 78189374

Centisome position: 73.18

GC content: 44.21

Gene sequence:

>1305_bases
ATGCTATCAAGGGATTTAGCTGAAGCGCCATCACAAACCAGAGTTATTATTTATTCTGGTAAAGGTGGTACGGGTAAAAC
CACCATTTCATCCTCAACCGCTGTGGCGTTAGCGCGCCAAAATAAGCGCGTGCTGATTATGTCGTCCGATCCAGCACACT
CGCTTTCCGATGTGTTTAATACCCGTATTAGCCGCAACGATCCCCAACAAATTGAAGGCTCACTCTATGGCTTAGAGGTT
GATACCATTTACGAGCTGAAAAAAAATATGGCTGGTTTTCAAAAATTTGTTTCCAGCTCCTATAAAAATCGTGGCATTGA
TAGCGGCATGGCTTCCGAACTTACCACGCAGCCCGGTCTCGATGAAATTTTTGCCCTCAGCCGTTTGCTTGATGAAGCGC
AATCGGGCAAATGGGATACCGTTGTGCTTGATACATCGCCCACCGGCAACACCTTACGCTTGCTTGCTTACCCCGAAATT
ATTATTGGTGGCAATATGGGCAAGCAGTTCTTTAAGCTCTACAAAAGCATGTCCTCCATTGCCCGTCCTTTAAATAGCAG
CAAATCACTACCCGATGATGAATTTTTTGAGGAAATTAATGTGCTCCTCAAACAAATGGAGGATATCAACAAATTTATCC
TAAGCCCTGAAGTTACCTTCCGCTTAGTACTCAATCCTGAAAAGCTCTCAATTCTTGAAACCAAGCGAGCCTACACCTTT
GTGCATCTTTACGGGATTAACATTGATGGCATTGTTATCAATAAAATTTTACCCGAATCAACTACTGTTGGCGAATACTT
TGAGTTTTGGTCAAACCTGCATAGCAAATATTTAATGGAAATTGACCAATCCTTTTACCCAACCCCCGTGTTCCGTTGCC
ACTTGCAACGCACAGAGCCTATTGGCACCGATGCGCTGCACGACATCAGCAAAATGGTTTTTGGCGAACAAAGTTCCGAT
AAGATTTTTTACACAGGTAAGAACTTTTGGATTGAAAGCCGCAAAAACGAAGCTTCTGACGACTTACACGAAGTGCTTTG
CATTCGCATTCCCTTTTTACAAGATGCCGAAGAGGTTAATGTGGAACGCATGGGCACCGATATTGTTGTAACGGTTGACC
GAGCACAACGCATTATTACCTTGCCACGGGCGCTCTACAATCTTGAAATGGAAAAATTTGTGCGCGAGGATAATTGCTTG
CGCGTTATGTTCCGTGAGCTGCATCCCGAAAAAGAGGAAAGCGAGCTGAACGTCAATAAAAACGTGCTTGAAAAGCTCCG
CTCCATGCGTCGCATGAAGTTGTAA

Upstream 100 bases:

>100_bases
CGCTACCGATGGGAAAAATTGTACCTTTAGCGCTTTGCGGCATTCAATCAAGAATTGGTTTCAATTTAAACGAGCATTTT
TTAATAGGATAACCTCTACT

Downstream 100 bases:

>100_bases
GAGGAATGAGAAATAAATTCCTTTTACTATATTTTTAGGTTTTCAGTTGAAAACCGTATCTTGAACACTTACAGTCCCCC
GACGACAAGGGAATTATCCC

Product: anion-transporting ATPase

Products: NA

Alternate protein names: Arsenical resistance ATPase; Arsenite-translocating ATPase; Arsenite-transporting ATPase [H]

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MLSRDLAEAPSQTRVIIYSGKGGTGKTTISSSTAVALARQNKRVLIMSSDPAHSLSDVFNTRISRNDPQQIEGSLYGLEV
DTIYELKKNMAGFQKFVSSSYKNRGIDSGMASELTTQPGLDEIFALSRLLDEAQSGKWDTVVLDTSPTGNTLRLLAYPEI
IIGGNMGKQFFKLYKSMSSIARPLNSSKSLPDDEFFEEINVLLKQMEDINKFILSPEVTFRLVLNPEKLSILETKRAYTF
VHLYGINIDGIVINKILPESTTVGEYFEFWSNLHSKYLMEIDQSFYPTPVFRCHLQRTEPIGTDALHDISKMVFGEQSSD
KIFYTGKNFWIESRKNEASDDLHEVLCIRIPFLQDAEEVNVERMGTDIVVTVDRAQRIITLPRALYNLEMEKFVREDNCL
RVMFRELHPEKEESELNVNKNVLEKLRSMRRMKL

Sequences:

>Translated_434_residues
MLSRDLAEAPSQTRVIIYSGKGGTGKTTISSSTAVALARQNKRVLIMSSDPAHSLSDVFNTRISRNDPQQIEGSLYGLEV
DTIYELKKNMAGFQKFVSSSYKNRGIDSGMASELTTQPGLDEIFALSRLLDEAQSGKWDTVVLDTSPTGNTLRLLAYPEI
IIGGNMGKQFFKLYKSMSSIARPLNSSKSLPDDEFFEEINVLLKQMEDINKFILSPEVTFRLVLNPEKLSILETKRAYTF
VHLYGINIDGIVINKILPESTTVGEYFEFWSNLHSKYLMEIDQSFYPTPVFRCHLQRTEPIGTDALHDISKMVFGEQSSD
KIFYTGKNFWIESRKNEASDDLHEVLCIRIPFLQDAEEVNVERMGTDIVVTVDRAQRIITLPRALYNLEMEKFVREDNCL
RVMFRELHPEKEESELNVNKNVLEKLRSMRRMKL
>Mature_434_residues
MLSRDLAEAPSQTRVIIYSGKGGTGKTTISSSTAVALARQNKRVLIMSSDPAHSLSDVFNTRISRNDPQQIEGSLYGLEV
DTIYELKKNMAGFQKFVSSSYKNRGIDSGMASELTTQPGLDEIFALSRLLDEAQSGKWDTVVLDTSPTGNTLRLLAYPEI
IIGGNMGKQFFKLYKSMSSIARPLNSSKSLPDDEFFEEINVLLKQMEDINKFILSPEVTFRLVLNPEKLSILETKRAYTF
VHLYGINIDGIVINKILPESTTVGEYFEFWSNLHSKYLMEIDQSFYPTPVFRCHLQRTEPIGTDALHDISKMVFGEQSSD
KIFYTGKNFWIESRKNEASDDLHEVLCIRIPFLQDAEEVNVERMGTDIVVTVDRAQRIITLPRALYNLEMEKFVREDNCL
RVMFRELHPEKEESELNVNKNVLEKLRSMRRMKL

Specific function: Anion-transporting ATPase. Catalyzes the extrusion of arsenite [H]

COG id: COG0003

COG function: function code P; Oxyanion-translocating ATPase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arsA ATPase family [H]

Homologues:

Organism=Homo sapiens, GI50428938, Length=296, Percent_Identity=25.6756756756757, Blast_Score=90, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17557003, Length=306, Percent_Identity=26.4705882352941, Blast_Score=99, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6320103, Length=308, Percent_Identity=25.974025974026, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24586297, Length=239, Percent_Identity=27.6150627615063, Blast_Score=96, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003348 [H]

Pfam domain/function: NA

EC number: =3.6.3.16 [H]

Molecular weight: Translated: 49531; Mature: 49531

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSRDLAEAPSQTRVIIYSGKGGTGKTTISSSTAVALARQNKRVLIMSSDPAHSLSDVFN
CCCCCHHCCCCCCEEEEEECCCCCCCEEECCCCEEEEEECCCEEEEEECCCCHHHHHHHH
TRISRNDPQQIEGSLYGLEVDTIYELKKNMAGFQKFVSSSYKNRGIDSGMASELTTQPGL
HHCCCCCCHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCH
DEIFALSRLLDEAQSGKWDTVVLDTSPTGNTLRLLAYPEIIIGGNMGKQFFKLYKSMSSI
HHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEECCCEEEECCCCHHHHHHHHHHHHH
ARPLNSSKSLPDDEFFEEINVLLKQMEDINKFILSPEVTFRLVLNPEKLSILETKRAYTF
HHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHCCEEEE
VHLYGINIDGIVINKILPESTTVGEYFEFWSNLHSKYLMEIDQSFYPTPVFRCHLQRTEP
EEEEECCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCC
IGTDALHDISKMVFGEQSSDKIFYTGKNFWIESRKNEASDDLHEVLCIRIPFLQDAEEVN
CCCHHHHHHHHHHCCCCCCCEEEECCCCEEEECCCCCCHHHHHHHHHHCCCCCCCHHHCC
VERMGTDIVVTVDRAQRIITLPRALYNLEMEKFVREDNCLRVMFRELHPEKEESELNVNK
HHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHCCCCH
NVLEKLRSMRRMKL
HHHHHHHHHHHCCC
>Mature Secondary Structure
MLSRDLAEAPSQTRVIIYSGKGGTGKTTISSSTAVALARQNKRVLIMSSDPAHSLSDVFN
CCCCCHHCCCCCCEEEEEECCCCCCCEEECCCCEEEEEECCCEEEEEECCCCHHHHHHHH
TRISRNDPQQIEGSLYGLEVDTIYELKKNMAGFQKFVSSSYKNRGIDSGMASELTTQPGL
HHCCCCCCHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCH
DEIFALSRLLDEAQSGKWDTVVLDTSPTGNTLRLLAYPEIIIGGNMGKQFFKLYKSMSSI
HHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEECCCEEEECCCCHHHHHHHHHHHHH
ARPLNSSKSLPDDEFFEEINVLLKQMEDINKFILSPEVTFRLVLNPEKLSILETKRAYTF
HHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHCCEEEE
VHLYGINIDGIVINKILPESTTVGEYFEFWSNLHSKYLMEIDQSFYPTPVFRCHLQRTEP
EEEEECCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCC
IGTDALHDISKMVFGEQSSDKIFYTGKNFWIESRKNEASDDLHEVLCIRIPFLQDAEEVN
CCCHHHHHHHHHHCCCCCCCEEEECCCCEEEECCCCCCHHHHHHHHHHCCCCCCCHHHCC
VERMGTDIVVTVDRAQRIITLPRALYNLEMEKFVREDNCLRVMFRELHPEKEESELNVNK
HHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHCCCCH
NVLEKLRSMRRMKL
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12093901 [H]