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The map label for this gene is kipA [H]

Identifier: 78067753

GI number: 78067753

Start: 3445699

End: 3446694

Strand: Direct

Name: kipA [H]

Synonym: Bcep18194_A6284

Alternate gene names: 78067753

Gene position: 3445699-3446694 (Clockwise)

Preceding gene: 78067752

Following gene: 78067754

Centisome position: 93.28

GC content: 70.48

Gene sequence:

>996_bases
ATGCAAACTGACGCGCACAACCTGATCGAAGTCGTGAAACCCGGCCTCGCGACGTCGGTCCAGGACATGGGCCGGCAAGG
CTATTACCACGTCGGCATTCCGCCGTCGGGCTCGCTCGACCAGTACGCGTCGCGCGCGGCGAACCTGCTGGTCGGCAATC
CCGAAGACGCGGCCGTGCTCGAATGCACGCTGCTCGGCCCCGAGCTGATGTTCCATACGGACGCGCTGATCGCCGTCACC
GGCGCCGAGATGACACCGAAGATCGACGGTGTCGGACAGCGCTGCAACGTCGCGCTGTGGATCCGCGCGGGCAGCGTGCT
GTCGTTCAATTACGTGAAGGCGGGCGCGCGCGCGTATCTCGCCGTCGCGGGCGGCATCGACGTGCCGGTCGTGCTCGGCA
GCCGCTCGACCTACACGCTCGGCGCGATCGGCGGCCACGCGGGCCGGCGCCTGCAGAAAGGCGACCGGCTGCCGATCGGC
ATCCCCGTCGGCACGCACCGCGAAGGGCGCGAGCTGCCGGCGGCCGTGAGCCGGCCGCTCGACAACCAGGTCGAGCTGCG
CGTGCTGACGGGCCTGTACCACTACCGGCTCACCGACGATTCGGCGCGCACCTTCTTCGACGACGAATGGACGGTCGCGC
CCGAAGCCGACCGCATCGGCTACCGCTACAAGAACGGCCGCGCGCTGCAGTTCCGGCCGCGCGAGCAGCCGTTCGGCGCG
GGCGCCGATCCGTCGAACATCGTCGATGCGTGCTACCCGATCGGCTCGATCCAGGTGCCGGCCGGGCTCGAGCCGATCAT
CCTGCACCGCGACGCGGTGTCGGGCGGCGGCTACGCGACGATCGGCACGGTCATCAGCGCCGACATGGACCTGATCGGCC
AGATGCAGCCCAACCACCGTGCGCGCTTCGTGCGCGTGACGATGGCCGACGCGCTCGCCGCGCGCCGCGAGTATCAGCGG
CGCCTCGCGCTGCTGCGCGCCGTGCTGCGGGACTGA

Upstream 100 bases:

>100_bases
GCCGGCACCTTCTCGCTGCGCGTGCGCCCGGTGAAATTCTCGCTCGACGCATTCCTGCGCGATCCCGATGCGGTCAACCG
CTCTCTCGTCGAGGTGCTGC

Downstream 100 bases:

>100_bases
GCACCGGGCGCCCGGCCCGCGTGCCGGGCGTCGTTCGCCACCACCCTTTTTTCGCTGTCGTTTCCCGCCCGCACGGCTGT
GCGCCGCGCGGCGGGGACGC

Product: allophanate hydrolase

Products: NA

Alternate protein names: Protein kipA [H]

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MQTDAHNLIEVVKPGLATSVQDMGRQGYYHVGIPPSGSLDQYASRAANLLVGNPEDAAVLECTLLGPELMFHTDALIAVT
GAEMTPKIDGVGQRCNVALWIRAGSVLSFNYVKAGARAYLAVAGGIDVPVVLGSRSTYTLGAIGGHAGRRLQKGDRLPIG
IPVGTHREGRELPAAVSRPLDNQVELRVLTGLYHYRLTDDSARTFFDDEWTVAPEADRIGYRYKNGRALQFRPREQPFGA
GADPSNIVDACYPIGSIQVPAGLEPIILHRDAVSGGGYATIGTVISADMDLIGQMQPNHRARFVRVTMADALAARREYQR
RLALLRAVLRD

Sequences:

>Translated_331_residues
MQTDAHNLIEVVKPGLATSVQDMGRQGYYHVGIPPSGSLDQYASRAANLLVGNPEDAAVLECTLLGPELMFHTDALIAVT
GAEMTPKIDGVGQRCNVALWIRAGSVLSFNYVKAGARAYLAVAGGIDVPVVLGSRSTYTLGAIGGHAGRRLQKGDRLPIG
IPVGTHREGRELPAAVSRPLDNQVELRVLTGLYHYRLTDDSARTFFDDEWTVAPEADRIGYRYKNGRALQFRPREQPFGA
GADPSNIVDACYPIGSIQVPAGLEPIILHRDAVSGGGYATIGTVISADMDLIGQMQPNHRARFVRVTMADALAARREYQR
RLALLRAVLRD
>Mature_331_residues
MQTDAHNLIEVVKPGLATSVQDMGRQGYYHVGIPPSGSLDQYASRAANLLVGNPEDAAVLECTLLGPELMFHTDALIAVT
GAEMTPKIDGVGQRCNVALWIRAGSVLSFNYVKAGARAYLAVAGGIDVPVVLGSRSTYTLGAIGGHAGRRLQKGDRLPIG
IPVGTHREGRELPAAVSRPLDNQVELRVLTGLYHYRLTDDSARTFFDDEWTVAPEADRIGYRYKNGRALQFRPREQPFGA
GADPSNIVDACYPIGSIQVPAGLEPIILHRDAVSGGGYATIGTVISADMDLIGQMQPNHRARFVRVTMADALAARREYQR
RLALLRAVLRD

Specific function: Counteracts the inhibitory action of kipI on sporulation. May bind to kipI, preventing its function as an inhibitor of kinase A [H]

COG id: COG1984

COG function: function code E; Allophanate hydrolase subunit 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786930, Length=318, Percent_Identity=35.8490566037736, Blast_Score=172, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6319685, Length=309, Percent_Identity=35.5987055016181, Blast_Score=171, Evalue=2e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003778 [H]

Pfam domain/function: PF02626 AHS2 [H]

EC number: NA

Molecular weight: Translated: 35767; Mature: 35767

Theoretical pI: Translated: 8.09; Mature: 8.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTDAHNLIEVVKPGLATSVQDMGRQGYYHVGIPPSGSLDQYASRAANLLVGNPEDAAVL
CCCCHHHHHHHHCCCHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHEEECCCCCCEEE
ECTLLGPELMFHTDALIAVTGAEMTPKIDGVGQRCNVALWIRAGSVLSFNYVKAGARAYL
EEEEECCHHEEECCEEEEEECCCCCCCCCCCCCCCCEEEEEECCCEEEEHHHHCCCEEEE
AVAGGIDVPVVLGSRSTYTLGAIGGHAGRRLQKGDRLPIGIPVGTHREGRELPAAVSRPL
EEECCCCEEEEECCCCEEEEEECCCCCCCHHHCCCCCEEECCCCCCCCCCCCCHHHCCCC
DNQVELRVLTGLYHYRLTDDSARTFFDDEWTVAPEADRIGYRYKNGRALQFRPREQPFGA
CCCEEEEEEEEEEEEEECCCCCCEEECCCEEECCCHHHCCEEECCCCEEEECCCCCCCCC
GADPSNIVDACYPIGSIQVPAGLEPIILHRDAVSGGGYATIGTVISADMDLIGQMQPNHR
CCCHHHHHHHHCCCCCEECCCCCCEEEEEECCCCCCCEEEEHHHHHHCHHHHCCCCCCCC
ARFVRVTMADALAARREYQRRLALLRAVLRD
EEEEEEEHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQTDAHNLIEVVKPGLATSVQDMGRQGYYHVGIPPSGSLDQYASRAANLLVGNPEDAAVL
CCCCHHHHHHHHCCCHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHEEECCCCCCEEE
ECTLLGPELMFHTDALIAVTGAEMTPKIDGVGQRCNVALWIRAGSVLSFNYVKAGARAYL
EEEEECCHHEEECCEEEEEECCCCCCCCCCCCCCCCEEEEEECCCEEEEHHHHCCCEEEE
AVAGGIDVPVVLGSRSTYTLGAIGGHAGRRLQKGDRLPIGIPVGTHREGRELPAAVSRPL
EEECCCCEEEEECCCCEEEEEECCCCCCCHHHCCCCCEEECCCCCCCCCCCCCHHHCCCC
DNQVELRVLTGLYHYRLTDDSARTFFDDEWTVAPEADRIGYRYKNGRALQFRPREQPFGA
CCCEEEEEEEEEEEEEECCCCCCEEECCCEEECCCHHHCCEEECCCCEEEECCCCCCCCC
GADPSNIVDACYPIGSIQVPAGLEPIILHRDAVSGGGYATIGTVISADMDLIGQMQPNHR
CCCHHHHHHHHCCCCCEECCCCCCEEEEEECCCCCCCEEEEHHHHHHCHHHHCCCCCCCC
ARFVRVTMADALAARREYQRRLALLRAVLRD
EEEEEEEHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 10568751 [H]