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The map label for this gene is bioD

Identifier: 78067746

GI number: 78067746

Start: 3439274

End: 3439993

Strand: Direct

Name: bioD

Synonym: Bcep18194_A6277

Alternate gene names: 78067746

Gene position: 3439274-3439993 (Clockwise)

Preceding gene: 78067745

Following gene: 78067747

Centisome position: 93.1

GC content: 71.25

Gene sequence:

>720_bases
ATGACCGCTCCGCTCTCGCTGTTCGTCACCGGCACCGACACCGAAATCGGCAAGACCTTCGTGTCGGCCGCGCTGCTGCA
CGGCTTCGCGCGCCACGGCCTGCGCGCAGCCGCGCTGAAACCTGTCGCAGCCGGCGCGTATGAACGCGACGGCGTGTGGC
GCAACGAAGATGCCGACCAGCTCGACGCGGCCGCGAACGTCGTGCTGCCGCCCGAGCTGCGCACGCCGTTCCTGCTGAAA
GCACCGGCCGCGCCGCATATCGTCGCCGCGCAGGAAGGCGTGACGCTCGACATCGACACGATCGTCGCGTGCCATCGCGA
AGCGCTGACGCGCGCGGATGTCGTCGTCGTCGAAGGCGCCGGCGGCTTCCGCGTACCGATGAACGACACGCAGGACCTGG
CCGATCTCGCAGTCGCGCTCGGCGTGCCGGTCGTGCTCGTGGTCGGCGTGCGGCTCGGCTGCATCAACCACGCGCTGCTC
ACCGCCGATGCGATCGCCGCGCGCGGCCTCAAGCTCGCCGGCTGGGTCGCGAACCACGTCGACCCGGCGATGTCGTTCCC
CGACGAGAACATCGCGACGATGCGCGACTGGCTCGCCCGCGAGCACGGCGCACCGCTGCTCGGCCGCATTCCGCACATGA
GCCCGGCCGCCCCCGAATCCGCCGCGGCGATGCTCGACATCGCCGCGCTCGTCGAGACGCTGCGCACCGCGCAGCCTTGA

Upstream 100 bases:

>100_bases
GCGTGTCGCTGTCGGCCGCGCATTCGTTCGACGATCTCGCGCGGCTCGAAGCCGCGCTGATCGAAGCCAGCGAAGCGCAG
GCCGTGCAGAAGGCCGCCGC

Downstream 100 bases:

>100_bases
CCCAACAGAAACAGATCCCCCGATCCCTCATCCCCGACCAGGACAGGAAAACGATATGACCCAAGCCCAGACTGCCGCCA
CCGTGCAACCCGACGCGATT

Product: dithiobiotin synthetase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase [H]

Number of amino acids: Translated: 239; Mature: 238

Protein sequence:

>239_residues
MTAPLSLFVTGTDTEIGKTFVSAALLHGFARHGLRAAALKPVAAGAYERDGVWRNEDADQLDAAANVVLPPELRTPFLLK
APAAPHIVAAQEGVTLDIDTIVACHREALTRADVVVVEGAGGFRVPMNDTQDLADLAVALGVPVVLVVGVRLGCINHALL
TADAIAARGLKLAGWVANHVDPAMSFPDENIATMRDWLAREHGAPLLGRIPHMSPAAPESAAAMLDIAALVETLRTAQP

Sequences:

>Translated_239_residues
MTAPLSLFVTGTDTEIGKTFVSAALLHGFARHGLRAAALKPVAAGAYERDGVWRNEDADQLDAAANVVLPPELRTPFLLK
APAAPHIVAAQEGVTLDIDTIVACHREALTRADVVVVEGAGGFRVPMNDTQDLADLAVALGVPVVLVVGVRLGCINHALL
TADAIAARGLKLAGWVANHVDPAMSFPDENIATMRDWLAREHGAPLLGRIPHMSPAAPESAAAMLDIAALVETLRTAQP
>Mature_238_residues
TAPLSLFVTGTDTEIGKTFVSAALLHGFARHGLRAAALKPVAAGAYERDGVWRNEDADQLDAAANVVLPPELRTPFLLKA
PAAPHIVAAQEGVTLDIDTIVACHREALTRADVVVVEGAGGFRVPMNDTQDLADLAVALGVPVVLVVGVRLGCINHALLT
ADAIAARGLKLAGWVANHVDPAMSFPDENIATMRDWLAREHGAPLLGRIPHMSPAAPESAAAMLDIAALVETLRTAQP

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786995, Length=215, Percent_Identity=45.5813953488372, Blast_Score=163, Evalue=1e-41,
Organism=Escherichia coli, GI87081944, Length=228, Percent_Identity=38.5964912280702, Blast_Score=143, Evalue=9e-36,
Organism=Saccharomyces cerevisiae, GI6324385, Length=172, Percent_Identity=36.046511627907, Blast_Score=79, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004472
- InterPro:   IPR002586 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: =6.3.3.3 [H]

Molecular weight: Translated: 25011; Mature: 24880

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAPLSLFVTGTDTEIGKTFVSAALLHGFARHGLRAAALKPVAAGAYERDGVWRNEDADQ
CCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCHHHHHCHHHCCCCCCCCCCCCCCHHH
LDAAANVVLPPELRTPFLLKAPAAPHIVAAQEGVTLDIDTIVACHREALTRADVVVVEGA
HHHHCCEEECCCCCCCEEEECCCCCCEEEECCCCEEEHHHHHHHHHHHHHHCCEEEEECC
GGFRVPMNDTQDLADLAVALGVPVVLVVGVRLGCINHALLTADAIAARGLKLAGWVANHV
CCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHC
DPAMSFPDENIATMRDWLAREHGAPLLGRIPHMSPAAPESAAAMLDIAALVETLRTAQP
CHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TAPLSLFVTGTDTEIGKTFVSAALLHGFARHGLRAAALKPVAAGAYERDGVWRNEDADQ
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCHHHHHCHHHCCCCCCCCCCCCCCHHH
LDAAANVVLPPELRTPFLLKAPAAPHIVAAQEGVTLDIDTIVACHREALTRADVVVVEGA
HHHHCCEEECCCCCCCEEEECCCCCCEEEECCCCEEEHHHHHHHHHHHHHHCCEEEEECC
GGFRVPMNDTQDLADLAVALGVPVVLVVGVRLGCINHALLTADAIAARGLKLAGWVANHV
CCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHC
DPAMSFPDENIATMRDWLAREHGAPLLGRIPHMSPAAPESAAAMLDIAALVETLRTAQP
CHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA