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The map label for this gene is qseC [H]

Identifier: 78067450

GI number: 78067450

Start: 3110914

End: 3112461

Strand: Direct

Name: qseC [H]

Synonym: Bcep18194_A5981

Alternate gene names: 78067450

Gene position: 3110914-3112461 (Clockwise)

Preceding gene: 78067449

Following gene: 78067451

Centisome position: 84.21

GC content: 71.32

Gene sequence:

>1548_bases
ATGGCCACGCCGGCCCATCCCCGCCACCCGACCGGCGCGCCGTCGTCGGCCGCCGACGAGGCGCGCGACGCGCGCTACGA
GAACCCGTTCGCGCCGCCCGACGAAACCGATGCGCCCGAGGCACCGCGCCCGCGCTCGCTGTTCGGCGAGATCCTCGACT
GGATGCTCGCCCCGCTGCTGCTGCTGTGGCCGATGAGCATCGCCGTCACCTATCTGGTCGCAAAGACGATCGCGAACGGC
CCGTTCGATCGCGCGCTCGAAACCAACGCCTATGTGCTCGCCCGCCAGATTCACCCGGTGAACGGTGTCGCCGAGCTGAC
GCTGCCGGAGCAGACCCGTGACTTCCTGCGCGCGGACAACGTCGACAGTGTTTACTTCCAGGTACTCGGCACGCGCGGCG
AGCTGGTCGCGGGCGAAGCCGACATGCCGCTGCCGCGCGACGAGGACCGCCCGCCGCCAGGCGTCGTGATGTTTCGCGAC
GACCTGCTGCGCGGCAACGACGTGCGCGTCGCGTATACGACGGTCGCGCTGCCGCAATCGGGCAGCCCGCAGCCCGTGCT
CGTGCAGGTCGGCGAAACGCTGGACAAGCGCAACGCGCTCGCGAACGACATCATCAAGGGCGTGATCCTGCCGCAGTTCG
TGATCCTGCCGCTCGCGATCCTGCTGGTCTGGTTCGGGCTGTCGCGCGGGCTCGCGCCGCTCAACGCGCTGCAGGCGCAC
ATCCGCGCGCGGCGGCCCGACGACCTGTCGCCGGTCGAGGCGCAGCGCGCGCCGCCCGAGATCGAGCCGCTCGTCACGTC
GTTCAACGACCTGCTCGCCCGTCTCGAACAGAACATGGCGCTGCAGAAGCGCTTCATCGCCGACGCCGCCCATCAGATGA
AGACGCCGCTCGCGGGCCTGCGCACGCAGGCCGAGTTCGCGCTGCGCCACCCCGTCCCGCCCGACGTGCAGCGCTCGCTC
GAGCAGATCGCGACGAGCTCCGAGCAGGCCGCGCGGCTTGTCACGCAACTGCTCGCACTCGCGCGCGCCGAGAACCGTGC
GAGCGGGCTGACGTTCGAGCCGGTCGAGATCGCCGCGCTCGCGCGACGCGCGGTGCGCGACTGGGTGCAGGCCGCGCTCG
CGAAACGGATGGATCTCGGCTACGAAGGCCCGCCGGACGATACGCCGCTCGACGTCGACGGCAATCCGGTGATGCTGCGC
GAGATGCTCGGCAACCTGATCGACAACGCGATCCGCTATACGCCGGACGGCGGCCGCATCACGGTGCGCGTGCGCGCCGA
GCCCGCGGCACGGCGCGTGCATCTCGAGGTCGAGGACACGGGGCCGGGCATCCCGGCCGCCGAACGCGAGCGCGTCGTCG
AGCGCTTCTACCGGATCCTCGGCCGCGAAGGCGACGGCAGCGGCCTCGGGCTCGCGATCGTGCGCGAGATCGCCACGCAG
CACGGCGGCACGCTGATGCTCGACGATCACGTCTACCAGCACGCACCGCGCCTCGCCGGCACGCTCGTGCGTGTCAGCCT
GCCGCTGACCGAAGCGGCCCCGGATTAA

Upstream 100 bases:

>100_bases
ATTGCCTCGAGAAGGTCGCGCCCGCCGCGCCGGCCGACACGGCCGCGCCCCAGCCCGCGGTGGCCGGCACGCCGCTGCGC
TGAACCCGGGCGTCGCCGCG

Downstream 100 bases:

>100_bases
CCCTGACGCGCACCACCGCGGCACGACGAGATTGCGCCGAAATCGGCAATTTGCCGGACGTTAAAAGCACTTCGCAGCAC
GATAGGCACACAAAACAACC

Product: periplasmic sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 515; Mature: 514

Protein sequence:

>515_residues
MATPAHPRHPTGAPSSAADEARDARYENPFAPPDETDAPEAPRPRSLFGEILDWMLAPLLLLWPMSIAVTYLVAKTIANG
PFDRALETNAYVLARQIHPVNGVAELTLPEQTRDFLRADNVDSVYFQVLGTRGELVAGEADMPLPRDEDRPPPGVVMFRD
DLLRGNDVRVAYTTVALPQSGSPQPVLVQVGETLDKRNALANDIIKGVILPQFVILPLAILLVWFGLSRGLAPLNALQAH
IRARRPDDLSPVEAQRAPPEIEPLVTSFNDLLARLEQNMALQKRFIADAAHQMKTPLAGLRTQAEFALRHPVPPDVQRSL
EQIATSSEQAARLVTQLLALARAENRASGLTFEPVEIAALARRAVRDWVQAALAKRMDLGYEGPPDDTPLDVDGNPVMLR
EMLGNLIDNAIRYTPDGGRITVRVRAEPAARRVHLEVEDTGPGIPAAERERVVERFYRILGREGDGSGLGLAIVREIATQ
HGGTLMLDDHVYQHAPRLAGTLVRVSLPLTEAAPD

Sequences:

>Translated_515_residues
MATPAHPRHPTGAPSSAADEARDARYENPFAPPDETDAPEAPRPRSLFGEILDWMLAPLLLLWPMSIAVTYLVAKTIANG
PFDRALETNAYVLARQIHPVNGVAELTLPEQTRDFLRADNVDSVYFQVLGTRGELVAGEADMPLPRDEDRPPPGVVMFRD
DLLRGNDVRVAYTTVALPQSGSPQPVLVQVGETLDKRNALANDIIKGVILPQFVILPLAILLVWFGLSRGLAPLNALQAH
IRARRPDDLSPVEAQRAPPEIEPLVTSFNDLLARLEQNMALQKRFIADAAHQMKTPLAGLRTQAEFALRHPVPPDVQRSL
EQIATSSEQAARLVTQLLALARAENRASGLTFEPVEIAALARRAVRDWVQAALAKRMDLGYEGPPDDTPLDVDGNPVMLR
EMLGNLIDNAIRYTPDGGRITVRVRAEPAARRVHLEVEDTGPGIPAAERERVVERFYRILGREGDGSGLGLAIVREIATQ
HGGTLMLDDHVYQHAPRLAGTLVRVSLPLTEAAPD
>Mature_514_residues
ATPAHPRHPTGAPSSAADEARDARYENPFAPPDETDAPEAPRPRSLFGEILDWMLAPLLLLWPMSIAVTYLVAKTIANGP
FDRALETNAYVLARQIHPVNGVAELTLPEQTRDFLRADNVDSVYFQVLGTRGELVAGEADMPLPRDEDRPPPGVVMFRDD
LLRGNDVRVAYTTVALPQSGSPQPVLVQVGETLDKRNALANDIIKGVILPQFVILPLAILLVWFGLSRGLAPLNALQAHI
RARRPDDLSPVEAQRAPPEIEPLVTSFNDLLARLEQNMALQKRFIADAAHQMKTPLAGLRTQAEFALRHPVPPDVQRSLE
QIATSSEQAARLVTQLLALARAENRASGLTFEPVEIAALARRAVRDWVQAALAKRMDLGYEGPPDDTPLDVDGNPVMLRE
MLGNLIDNAIRYTPDGGRITVRVRAEPAARRVHLEVEDTGPGIPAAERERVVERFYRILGREGDGSGLGLAIVREIATQH
GGTLMLDDHVYQHAPRLAGTLVRVSLPLTEAAPD

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC. May activate qseB by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=435, Percent_Identity=29.8850574712644, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1786783, Length=305, Percent_Identity=32.7868852459016, Blast_Score=142, Evalue=7e-35,
Organism=Escherichia coli, GI1790551, Length=288, Percent_Identity=32.9861111111111, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI1790861, Length=310, Percent_Identity=31.2903225806452, Blast_Score=112, Evalue=7e-26,
Organism=Escherichia coli, GI1786600, Length=224, Percent_Identity=32.1428571428571, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1788393, Length=282, Percent_Identity=28.3687943262411, Blast_Score=102, Evalue=8e-23,
Organism=Escherichia coli, GI145693157, Length=229, Percent_Identity=29.2576419213974, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1790346, Length=260, Percent_Identity=28.8461538461538, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1788279, Length=289, Percent_Identity=25.6055363321799, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI48994928, Length=206, Percent_Identity=28.6407766990291, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI1789149, Length=214, Percent_Identity=27.5700934579439, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI87082128, Length=239, Percent_Identity=30.1255230125523, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1790436, Length=221, Percent_Identity=27.6018099547511, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787374, Length=293, Percent_Identity=27.9863481228669, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI87081816, Length=239, Percent_Identity=27.6150627615063, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788713, Length=257, Percent_Identity=23.3463035019455, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1787894, Length=267, Percent_Identity=28.4644194756554, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1786912, Length=241, Percent_Identity=29.045643153527, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1789808, Length=233, Percent_Identity=28.3261802575107, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1788549, Length=226, Percent_Identity=22.5663716814159, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 56363; Mature: 56232

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATPAHPRHPTGAPSSAADEARDARYENPFAPPDETDAPEAPRPRSLFGEILDWMLAPLL
CCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
LLWPMSIAVTYLVAKTIANGPFDRALETNAYVLARQIHPVNGVAELTLPEQTRDFLRADN
HHHHHHHHHHHHHHHHHCCCCHHHHHCCCCEEEEECCCCCCCCEEECCCHHHHHHHHCCC
VDSVYFQVLGTRGELVAGEADMPLPRDEDRPPPGVVMFRDDLLRGNDVRVAYTTVALPQS
CHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEEEEEEECCCC
GSPQPVLVQVGETLDKRNALANDIIKGVILPQFVILPLAILLVWFGLSRGLAPLNALQAH
CCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
IRARRPDDLSPVEAQRAPPEIEPLVTSFNDLLARLEQNMALQKRFIADAAHQMKTPLAGL
HHCCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
RTQAEFALRHPVPPDVQRSLEQIATSSEQAARLVTQLLALARAENRASGLTFEPVEIAAL
HHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
ARRAVRDWVQAALAKRMDLGYEGPPDDTPLDVDGNPVMLREMLGNLIDNAIRYTPDGGRI
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEECCCCCEE
TVRVRAEPAARRVHLEVEDTGPGIPAAERERVVERFYRILGREGDGSGLGLAIVREIATQ
EEEEECCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
HGGTLMLDDHVYQHAPRLAGTLVRVSLPLTEAAPD
CCCEEEECCHHHHHCHHHHHEEEEEECCCCCCCCC
>Mature Secondary Structure 
ATPAHPRHPTGAPSSAADEARDARYENPFAPPDETDAPEAPRPRSLFGEILDWMLAPLL
CCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
LLWPMSIAVTYLVAKTIANGPFDRALETNAYVLARQIHPVNGVAELTLPEQTRDFLRADN
HHHHHHHHHHHHHHHHHCCCCHHHHHCCCCEEEEECCCCCCCCEEECCCHHHHHHHHCCC
VDSVYFQVLGTRGELVAGEADMPLPRDEDRPPPGVVMFRDDLLRGNDVRVAYTTVALPQS
CHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEEEEEEECCCC
GSPQPVLVQVGETLDKRNALANDIIKGVILPQFVILPLAILLVWFGLSRGLAPLNALQAH
CCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
IRARRPDDLSPVEAQRAPPEIEPLVTSFNDLLARLEQNMALQKRFIADAAHQMKTPLAGL
HHCCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
RTQAEFALRHPVPPDVQRSLEQIATSSEQAARLVTQLLALARAENRASGLTFEPVEIAAL
HHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
ARRAVRDWVQAALAKRMDLGYEGPPDDTPLDVDGNPVMLREMLGNLIDNAIRYTPDGGRI
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEECCCCCEE
TVRVRAEPAARRVHLEVEDTGPGIPAAERERVVERFYRILGREGDGSGLGLAIVREIATQ
EEEEECCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
HGGTLMLDDHVYQHAPRLAGTLVRVSLPLTEAAPD
CCCEEEECCHHHHHCHHHHHEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796; 11929534 [H]