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The map label for this gene is tctD [H]

Identifier: 78067449

GI number: 78067449

Start: 3110075

End: 3110896

Strand: Direct

Name: tctD [H]

Synonym: Bcep18194_A5980

Alternate gene names: 78067449

Gene position: 3110075-3110896 (Clockwise)

Preceding gene: 78067439

Following gene: 78067450

Centisome position: 84.19

GC content: 67.76

Gene sequence:

>822_bases
TTGTGCAAGCCCGCAATGCAGGCTACGTTGTACACGAATAACTTCGGAGACAGCCGGCCGGCGCAAACGCCCTGCCGGCC
ATCGGTCAGCACCATGCGAATTCTCATCGCGGAAGACGACAGCATACTCGCGGACGGCCTCACCCGGTCACTCCGCCAAT
CGGGCTATGCAGTCGACCACGTGAAGACCGGTGTCGACGCCGATACCGCGTTGTCGATGCAGACATTCGACCTGCTGATC
CTCGATCTCGGGCTCCCGAAAATGCCAGGGCTCGACGTGCTCAAGCGCCTGCGCGCCCGCAATTCCAACCTCCCCGTGCT
GATCCTGACGGCCGCCGACAGCGTCGACGAGCGCGTGAAGGGGCTCGACCTCGGCGCCGACGACTACATGGCCAAGCCGT
TCGCGCTCAACGAGCTCGAAGCGCGCGTGCGCGCGCTGACCCGGCGCGGCGCGGGCGGCGGCCCGACCGTCGTGCGCCAC
GGCTCGCTCGCGTTCGACCAGGTCGGCCGGATCGCGTATGCGAACGATCACGTGCTCGACCTCTCCGCGCGCGAGCTCGG
CCTGCTCGAGGTGCTACTGCAGCGGATCGGCCGGCTCGTGTCGAAGGAGCAGCTCGTCGACCATCTCTGCGAATGGGGCG
AGGAAGTCAGCAACAACGCGATCGAAGTCTACGTGCACCGGCTGCGCAAGAAGATCGAACCCAGCGGTGTACGGATCTCG
ACCGTGCGCGGCCTCGGCTATTGCCTCGAGAAGGTCGCGCCCGCCGCGCCGGCCGACACGGCCGCGCCCCAGCCCGCGGT
GGCCGGCACGCCGCTGCGCTGA

Upstream 100 bases:

>100_bases
CCATGAATCGTCCTTTGCTATGATGAGCAGCGTCTGTTAGAGGCGCGCCCGCTTTCAAGCGCCGCCCACGAATGCAGACA
CTGTATAAAAAAACAGTGTT

Downstream 100 bases:

>100_bases
ACCCGGGCGTCGCCGCGATGGCCACGCCGGCCCATCCCCGCCACCCGACCGGCGCGCCGTCGTCGGCCGCCGACGAGGCG
CGCGACGCGCGCTACGAGAA

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MCKPAMQATLYTNNFGDSRPAQTPCRPSVSTMRILIAEDDSILADGLTRSLRQSGYAVDHVKTGVDADTALSMQTFDLLI
LDLGLPKMPGLDVLKRLRARNSNLPVLILTAADSVDERVKGLDLGADDYMAKPFALNELEARVRALTRRGAGGGPTVVRH
GSLAFDQVGRIAYANDHVLDLSARELGLLEVLLQRIGRLVSKEQLVDHLCEWGEEVSNNAIEVYVHRLRKKIEPSGVRIS
TVRGLGYCLEKVAPAAPADTAAPQPAVAGTPLR

Sequences:

>Translated_273_residues
MCKPAMQATLYTNNFGDSRPAQTPCRPSVSTMRILIAEDDSILADGLTRSLRQSGYAVDHVKTGVDADTALSMQTFDLLI
LDLGLPKMPGLDVLKRLRARNSNLPVLILTAADSVDERVKGLDLGADDYMAKPFALNELEARVRALTRRGAGGGPTVVRH
GSLAFDQVGRIAYANDHVLDLSARELGLLEVLLQRIGRLVSKEQLVDHLCEWGEEVSNNAIEVYVHRLRKKIEPSGVRIS
TVRGLGYCLEKVAPAAPADTAAPQPAVAGTPLR
>Mature_273_residues
MCKPAMQATLYTNNFGDSRPAQTPCRPSVSTMRILIAEDDSILADGLTRSLRQSGYAVDHVKTGVDADTALSMQTFDLLI
LDLGLPKMPGLDVLKRLRARNSNLPVLILTAADSVDERVKGLDLGADDYMAKPFALNELEARVRALTRRGAGGGPTVVRH
GSLAFDQVGRIAYANDHVLDLSARELGLLEVLLQRIGRLVSKEQLVDHLCEWGEEVSNNAIEVYVHRLRKKIEPSGVRIS
TVRGLGYCLEKVAPAAPADTAAPQPAVAGTPLR

Specific function: Transcriptional activator of the tctI tricarboxylate transport system operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=218, Percent_Identity=44.954128440367, Blast_Score=181, Evalue=4e-47,
Organism=Escherichia coli, GI1790552, Length=218, Percent_Identity=43.1192660550459, Blast_Score=170, Evalue=1e-43,
Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=38.8392857142857, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1787375, Length=222, Percent_Identity=38.2882882882883, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1790860, Length=221, Percent_Identity=36.1990950226244, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI87082012, Length=224, Percent_Identity=35.2678571428571, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1789809, Length=229, Percent_Identity=34.061135371179, Blast_Score=117, Evalue=5e-28,
Organism=Escherichia coli, GI1786599, Length=222, Percent_Identity=33.3333333333333, Blast_Score=117, Evalue=8e-28,
Organism=Escherichia coli, GI1788394, Length=233, Percent_Identity=31.7596566523605, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1786911, Length=221, Percent_Identity=32.1266968325792, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI2367329, Length=231, Percent_Identity=33.3333333333333, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1788713, Length=115, Percent_Identity=40, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1787229, Length=226, Percent_Identity=29.2035398230088, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1790863, Length=238, Percent_Identity=26.0504201680672, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1790299, Length=144, Percent_Identity=31.9444444444444, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790437, Length=108, Percent_Identity=37.962962962963, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI145693140, Length=235, Percent_Identity=27.2340425531915, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1787487, Length=114, Percent_Identity=35.0877192982456, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=31.7757009345794, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 29557; Mature: 29557

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCKPAMQATLYTNNFGDSRPAQTPCRPSVSTMRILIAEDDSILADGLTRSLRQSGYAVDH
CCCCHHEEEEEECCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCHHH
VKTGVDADTALSMQTFDLLILDLGLPKMPGLDVLKRLRARNSNLPVLILTAADSVDERVK
HHCCCCCHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHCCCCCCEEEEECCCCHHHHHH
GLDLGADDYMAKPFALNELEARVRALTRRGAGGGPTVVRHGSLAFDQVGRIAYANDHVLD
CCCCCCHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCEEECCCCCHHHHCCEEECCCCEEE
LSARELGLLEVLLQRIGRLVSKEQLVDHLCEWGEEVSNNAIEVYVHRLRKKIEPSGVRIS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEE
TVRGLGYCLEKVAPAAPADTAAPQPAVAGTPLR
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MCKPAMQATLYTNNFGDSRPAQTPCRPSVSTMRILIAEDDSILADGLTRSLRQSGYAVDH
CCCCHHEEEEEECCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCHHH
VKTGVDADTALSMQTFDLLILDLGLPKMPGLDVLKRLRARNSNLPVLILTAADSVDERVK
HHCCCCCHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHCCCCCCEEEEECCCCHHHHHH
GLDLGADDYMAKPFALNELEARVRALTRRGAGGGPTVVRHGSLAFDQVGRIAYANDHVLD
CCCCCCHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCEEECCCCCHHHHCCEEECCCCEEE
LSARELGLLEVLLQRIGRLVSKEQLVDHLCEWGEEVSNNAIEVYVHRLRKKIEPSGVRIS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEE
TVRGLGYCLEKVAPAAPADTAAPQPAVAGTPLR
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2666399; 11083839; 11677609 [H]