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The map label for this gene is erg3 [H]

Identifier: 78067420

GI number: 78067420

Start: 3080160

End: 3081074

Strand: Direct

Name: erg3 [H]

Synonym: Bcep18194_A5951

Alternate gene names: 78067420

Gene position: 3080160-3081074 (Clockwise)

Preceding gene: 78067419

Following gene: 78067421

Centisome position: 83.38

GC content: 64.59

Gene sequence:

>915_bases
ATGCGATTCGACGTCGAATTGCTTCTGCTCGCGCTGGCGCCCGTCTTCCTGCTCTGCATCGCGTGGGAGGCCTGGCACCT
CGCCCGCACTCGTGCGCAGGACCACGTCTATGCGTGGCGCGACACGCTGTGCAACGCGGCGCTCGCCCTGATGCACCAGG
GCGCCGACAAGATCGCGTGGCTGTTCGTGATCCCCGTCTATGCGTACTGCTACCAGCACTATCGCCTGTTCACTTGGCAC
GACAGTTGGCTGTCGTTCGCGGTGCTGTTCGTCGCGCAGGATTTCCTCTACTACGTATTCCATCGCGCCAGCCATCGCGT
GCGCTGGCTGTGGGCCGCGCACGTCGTGCACCACTCGTCCGAGCGGATGAATTTCTCGACCGCGTTCCGCCAGAGCCTGA
TGTACCCGGTCGCGGGGATGTGGGTGTTCTGGCTGCCGCTCGCGTTCGTCGGCTTTCCGCCGCAACAGGTCGTCGGCATC
GTGCTGATCAACCTCGCGTTCCAGTTCTTCGTGCATACGCAGGCAATCGGCAAGCTCGGCTGGCTCGAATACGTGCTGAA
CACGCCGTCGATCCACCGCGCGCACCATGCGCGCAACCCGCGCTACATCGACCGCAATTACGCAGGCGTCCTTGTGATCT
GGGATCGCCTGTTCGGCAGCTATGTCGAGGAAACGCCCGATGATCCGCCGCAGTACGGGATCGTCGAGCGGCTCGGCTCG
AACAACCCGCTCGTCGCGACGTTCCACGAGTGGGTGTCGATGGCCGGCGACGCGTTGCGCGTCGACGGCTGGCGCAACAA
GCTGCGCGCGATTTTCGGCCCGCCCGAATGGGCGAGCGCTTATCATGCGCAGATTGCCGAGGCCGCGAACCCCGATCCGC
GCATCGTGCCGCTTGCGGCTGCGCGAGACCAATAA

Upstream 100 bases:

>100_bases
CTAGCGCGTGGCGATTGCGTAGGCTGTTGGCCTGACTGATATCTACAACGGGCCATACGCCCGGCCTCAAGGCTTGCAGG
GGAAAGAAGGAGACACGCCC

Downstream 100 bases:

>100_bases
ACCGTTTCAGCCAACGGCCGCCGCGCAGCCCGGAACCGAGCAGGCACGCGGCAGATGAGAAACACATCAGGCCATATCTA
CGAGGAGATCGAACGATGCA

Product: sterol desaturase-like

Products: NA

Alternate protein names: Sterol-C5-desaturase [H]

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MRFDVELLLLALAPVFLLCIAWEAWHLARTRAQDHVYAWRDTLCNAALALMHQGADKIAWLFVIPVYAYCYQHYRLFTWH
DSWLSFAVLFVAQDFLYYVFHRASHRVRWLWAAHVVHHSSERMNFSTAFRQSLMYPVAGMWVFWLPLAFVGFPPQQVVGI
VLINLAFQFFVHTQAIGKLGWLEYVLNTPSIHRAHHARNPRYIDRNYAGVLVIWDRLFGSYVEETPDDPPQYGIVERLGS
NNPLVATFHEWVSMAGDALRVDGWRNKLRAIFGPPEWASAYHAQIAEAANPDPRIVPLAAARDQ

Sequences:

>Translated_304_residues
MRFDVELLLLALAPVFLLCIAWEAWHLARTRAQDHVYAWRDTLCNAALALMHQGADKIAWLFVIPVYAYCYQHYRLFTWH
DSWLSFAVLFVAQDFLYYVFHRASHRVRWLWAAHVVHHSSERMNFSTAFRQSLMYPVAGMWVFWLPLAFVGFPPQQVVGI
VLINLAFQFFVHTQAIGKLGWLEYVLNTPSIHRAHHARNPRYIDRNYAGVLVIWDRLFGSYVEETPDDPPQYGIVERLGS
NNPLVATFHEWVSMAGDALRVDGWRNKLRAIFGPPEWASAYHAQIAEAANPDPRIVPLAAARDQ
>Mature_304_residues
MRFDVELLLLALAPVFLLCIAWEAWHLARTRAQDHVYAWRDTLCNAALALMHQGADKIAWLFVIPVYAYCYQHYRLFTWH
DSWLSFAVLFVAQDFLYYVFHRASHRVRWLWAAHVVHHSSERMNFSTAFRQSLMYPVAGMWVFWLPLAFVGFPPQQVVGI
VLINLAFQFFVHTQAIGKLGWLEYVLNTPSIHRAHHARNPRYIDRNYAGVLVIWDRLFGSYVEETPDDPPQYGIVERLGS
NNPLVATFHEWVSMAGDALRVDGWRNKLRAIFGPPEWASAYHAQIAEAANPDPRIVPLAAARDQ

Specific function: Unknown

COG id: COG3000

COG function: function code I; Sterol desaturase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sterol desaturase family [H]

Homologues:

Organism=Homo sapiens, GI51972212, Length=246, Percent_Identity=39.0243902439024, Blast_Score=164, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI25144659, Length=252, Percent_Identity=35.3174603174603, Blast_Score=146, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006694 [H]

Pfam domain/function: PF04116 FA_hydroxylase [H]

EC number: NA

Molecular weight: Translated: 35216; Mature: 35216

Theoretical pI: Translated: 7.82; Mature: 7.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCC
>Mature Secondary Structure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CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]