| Definition | Burkholderia sp. 383 chromosome 1, complete genome. |
|---|---|
| Accession | NC_007510 |
| Length | 3,694,126 |
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The map label for this gene is polS [H]
Identifier: 78067398
GI number: 78067398
Start: 3053305
End: 3054081
Strand: Reverse
Name: polS [H]
Synonym: Bcep18194_A5929
Alternate gene names: 78067398
Gene position: 3054081-3053305 (Counterclockwise)
Preceding gene: 78067403
Following gene: 78067397
Centisome position: 82.67
GC content: 69.37
Gene sequence:
>777_bases GTGAGACTGGAAGACAAGGTCGCGATCCTGACGGGCGCCGCAAGCGGCATCGGCGAGGCGGTCGCGCAACGCTATCTGGA CGAGGGCGCACGCTGCGTGCTCGTCGACCTGAAGCCGGCAGGCGGCTCGCTCGCGCGGCTCATCGAGGCGAACCCCGGCC GCGCGGTGGCCGTCACCGCGGACGTCACGCGCCGCGACGACATCGAGCGGATCGTCGCGACGACGGTCGAGCGCTTCGGC GGCGTCGACATCCTGTTCAACAACGCGGCGCTGTTCGACATGCGCCCGATCCTCGACGAATCGTGGGACGTGTTCGACCG GCTGTTCTCGGTCAACGTGAAAGGGCTGTTCTTCCTGATGCAGGCCGTCGCGCAGCGGATGGTCGAGCAGGGGCGCGGCG GCAAGATCGTCAACATGTCGTCGCAGGCCGGGCGTCGTGGCGAGGCACTCGTTTCGCACTACTGCGCGACCAAGGCCGCG GTGATCAGCTATACGCAGTCGGCCGCGCTCGCGCTCGCGCCGCACCGGATCAACGTGAACGGCATCGCGCCGGGCGTCGT CGACACGCCGATGTGGGAGCAGGTCGATGCGCTGTTCGCGCGCTACGAGAACCGGCCGCTCGGCGAGAAGAAGCGGCTCG TCGGCGAAGCCGTGCCGCTCGGCCGCATGGGCGTGCCGGGCGACCTGACCGGCGCGGCGCTGTTCCTCGCGTCGTCCGAC GCCGACTACGTTACCGCCCAGACGCTGAACGTCGACGGCGGCAACTGGATGAGCTGA
Upstream 100 bases:
>100_bases GCGTATCCGATCATTCGATCACTAACAGAGCAATTGATCGGTTGGCGAGCGTTCGCTCACCTCGCGGCCGTCGTGAAGCA GAACGAACCGGAGACAGCCA
Downstream 100 bases:
>100_bases TATGGTGCCGCTCGCACGCGCCATTTGCCGGCCGGCTCGCGACGCAGCGGTGTCGCCGCACGCCGCGGCCGCCGTCGAAC GAGGAGGGGCCGCCTGATGG
Product: sorbitol dehydrogenase
Products: NA
Alternate protein names: L-iditol 2-dehydrogenase; Polyol dehydrogenase [H]
Number of amino acids: Translated: 258; Mature: 258
Protein sequence:
>258_residues MRLEDKVAILTGAASGIGEAVAQRYLDEGARCVLVDLKPAGGSLARLIEANPGRAVAVTADVTRRDDIERIVATTVERFG GVDILFNNAALFDMRPILDESWDVFDRLFSVNVKGLFFLMQAVAQRMVEQGRGGKIVNMSSQAGRRGEALVSHYCATKAA VISYTQSAALALAPHRINVNGIAPGVVDTPMWEQVDALFARYENRPLGEKKRLVGEAVPLGRMGVPGDLTGAALFLASSD ADYVTAQTLNVDGGNWMS
Sequences:
>Translated_258_residues MRLEDKVAILTGAASGIGEAVAQRYLDEGARCVLVDLKPAGGSLARLIEANPGRAVAVTADVTRRDDIERIVATTVERFG GVDILFNNAALFDMRPILDESWDVFDRLFSVNVKGLFFLMQAVAQRMVEQGRGGKIVNMSSQAGRRGEALVSHYCATKAA VISYTQSAALALAPHRINVNGIAPGVVDTPMWEQVDALFARYENRPLGEKKRLVGEAVPLGRMGVPGDLTGAALFLASSD ADYVTAQTLNVDGGNWMS >Mature_258_residues MRLEDKVAILTGAASGIGEAVAQRYLDEGARCVLVDLKPAGGSLARLIEANPGRAVAVTADVTRRDDIERIVATTVERFG GVDILFNNAALFDMRPILDESWDVFDRLFSVNVKGLFFLMQAVAQRMVEQGRGGKIVNMSSQAGRRGEALVSHYCATKAA VISYTQSAALALAPHRINVNGIAPGVVDTPMWEQVDALFARYENRPLGEKKRLVGEAVPLGRMGVPGDLTGAALFLASSD ADYVTAQTLNVDGGNWMS
Specific function: Catalyzes the oxidation of D-glucitol (sorbitol) to D- fructose, galactitol to D-tagatose and of L-iditol [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI15277342, Length=268, Percent_Identity=34.3283582089552, Blast_Score=126, Evalue=2e-29, Organism=Homo sapiens, GI32483357, Length=259, Percent_Identity=33.976833976834, Blast_Score=124, Evalue=1e-28, Organism=Homo sapiens, GI7705925, Length=254, Percent_Identity=34.251968503937, Blast_Score=120, Evalue=1e-27, Organism=Homo sapiens, GI59889578, Length=235, Percent_Identity=34.8936170212766, Blast_Score=119, Evalue=3e-27, Organism=Homo sapiens, GI19923817, Length=260, Percent_Identity=28.8461538461538, Blast_Score=106, Evalue=2e-23, Organism=Homo sapiens, GI10190704, Length=261, Percent_Identity=31.0344827586207, Blast_Score=104, Evalue=7e-23, Organism=Homo sapiens, GI126723750, Length=265, Percent_Identity=31.3207547169811, Blast_Score=102, Evalue=3e-22, Organism=Homo sapiens, GI5031737, Length=253, Percent_Identity=30.8300395256917, Blast_Score=100, Evalue=1e-21, Organism=Homo sapiens, GI66933014, Length=257, Percent_Identity=33.852140077821, Blast_Score=95, Evalue=6e-20, Organism=Homo sapiens, GI31542939, Length=202, Percent_Identity=32.1782178217822, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI4758504, Length=264, Percent_Identity=29.1666666666667, Blast_Score=93, Evalue=2e-19, Organism=Homo sapiens, GI40254992, Length=256, Percent_Identity=29.296875, Blast_Score=92, Evalue=5e-19, Organism=Homo sapiens, GI33667109, Length=245, Percent_Identity=31.0204081632653, Blast_Score=89, Evalue=5e-18, Organism=Homo sapiens, GI4504505, Length=194, Percent_Identity=31.4432989690722, Blast_Score=81, Evalue=1e-15, Organism=Homo sapiens, GI83715985, Length=180, Percent_Identity=32.2222222222222, Blast_Score=80, Evalue=1e-15, Organism=Homo sapiens, GI126723191, Length=184, Percent_Identity=32.0652173913043, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI224922801, Length=173, Percent_Identity=31.7919075144509, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI20149619, Length=196, Percent_Identity=31.1224489795918, Blast_Score=78, Evalue=1e-14, Organism=Homo sapiens, GI109715829, Length=198, Percent_Identity=32.3232323232323, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI40807363, Length=195, Percent_Identity=27.6923076923077, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI4503817, Length=220, Percent_Identity=26.8181818181818, Blast_Score=73, Evalue=2e-13, Organism=Homo sapiens, GI310128830, Length=200, Percent_Identity=29, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI310115468, Length=200, Percent_Identity=29, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI7706318, Length=193, Percent_Identity=29.5336787564767, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI4503301, Length=229, Percent_Identity=24.4541484716157, Blast_Score=67, Evalue=2e-11, Organism=Escherichia coli, GI1789208, Length=256, Percent_Identity=35.15625, Blast_Score=145, Evalue=3e-36, Organism=Escherichia coli, GI87082100, Length=262, Percent_Identity=34.7328244274809, Blast_Score=125, Evalue=4e-30, Organism=Escherichia coli, GI87082160, Length=254, Percent_Identity=33.8582677165354, Blast_Score=121, Evalue=4e-29, Organism=Escherichia coli, GI1788459, Length=251, Percent_Identity=32.2709163346614, Blast_Score=118, Evalue=5e-28, Organism=Escherichia coli, GI1790717, Length=255, Percent_Identity=31.7647058823529, Blast_Score=117, Evalue=1e-27, Organism=Escherichia coli, GI1787335, Length=263, Percent_Identity=32.6996197718631, Blast_Score=116, Evalue=2e-27, Organism=Escherichia coli, GI1787905, Length=260, Percent_Identity=35.3846153846154, Blast_Score=112, Evalue=2e-26, Organism=Escherichia coli, GI1789057, Length=261, Percent_Identity=30.2681992337165, Blast_Score=99, Evalue=3e-22, Organism=Escherichia coli, GI1789378, Length=263, Percent_Identity=29.277566539924, Blast_Score=99, Evalue=3e-22, Organism=Escherichia coli, GI1786812, Length=261, Percent_Identity=33.3333333333333, Blast_Score=93, Evalue=2e-20, Organism=Escherichia coli, GI2367175, Length=257, Percent_Identity=28.7937743190661, Blast_Score=79, Evalue=3e-16, Organism=Escherichia coli, GI2367365, Length=249, Percent_Identity=28.9156626506024, Blast_Score=75, Evalue=4e-15, Organism=Escherichia coli, GI1787820, Length=182, Percent_Identity=29.6703296703297, Blast_Score=73, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17561402, Length=256, Percent_Identity=33.59375, Blast_Score=135, Evalue=2e-32, Organism=Caenorhabditis elegans, GI25147288, Length=256, Percent_Identity=32.03125, Blast_Score=123, Evalue=7e-29, Organism=Caenorhabditis elegans, GI17555706, Length=262, Percent_Identity=33.206106870229, Blast_Score=119, Evalue=2e-27, Organism=Caenorhabditis elegans, GI17560332, Length=278, Percent_Identity=30.9352517985612, Blast_Score=117, Evalue=6e-27, Organism=Caenorhabditis elegans, GI17560220, Length=278, Percent_Identity=29.8561151079137, Blast_Score=115, Evalue=2e-26, Organism=Caenorhabditis elegans, GI71994600, Length=264, Percent_Identity=32.5757575757576, Blast_Score=115, Evalue=2e-26, Organism=Caenorhabditis elegans, GI17538480, Length=266, Percent_Identity=31.5789473684211, Blast_Score=108, Evalue=2e-24, Organism=Caenorhabditis elegans, GI17562906, Length=271, Percent_Identity=29.8892988929889, Blast_Score=108, Evalue=2e-24, Organism=Caenorhabditis elegans, GI71994604, Length=255, Percent_Identity=32.5490196078431, Blast_Score=108, Evalue=4e-24, Organism=Caenorhabditis elegans, GI17562990, Length=275, Percent_Identity=29.0909090909091, Blast_Score=106, Evalue=1e-23, Organism=Caenorhabditis elegans, GI17560150, Length=276, Percent_Identity=28.9855072463768, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI17562904, Length=274, Percent_Identity=29.5620437956204, Blast_Score=104, Evalue=4e-23, Organism=Caenorhabditis elegans, GI17544670, Length=271, Percent_Identity=28.7822878228782, Blast_Score=103, Evalue=1e-22, Organism=Caenorhabditis elegans, GI72000259, Length=271, Percent_Identity=28.7822878228782, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17531453, Length=278, Percent_Identity=28.0575539568345, Blast_Score=102, Evalue=3e-22, Organism=Caenorhabditis elegans, GI17560676, Length=258, Percent_Identity=31.7829457364341, Blast_Score=101, Evalue=3e-22, Organism=Caenorhabditis elegans, GI17559104, Length=272, Percent_Identity=30.5147058823529, Blast_Score=100, Evalue=1e-21, Organism=Caenorhabditis elegans, GI17562908, Length=271, Percent_Identity=28.4132841328413, Blast_Score=99, Evalue=3e-21, Organism=Caenorhabditis elegans, GI17563726, Length=276, Percent_Identity=27.8985507246377, Blast_Score=98, Evalue=4e-21, Organism=Caenorhabditis elegans, GI193204405, Length=278, Percent_Identity=27.3381294964029, Blast_Score=98, Evalue=5e-21, Organism=Caenorhabditis elegans, GI17551412, Length=270, Percent_Identity=29.6296296296296, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17562910, Length=274, Percent_Identity=28.1021897810219, Blast_Score=95, Evalue=4e-20, Organism=Caenorhabditis elegans, GI115534694, Length=254, Percent_Identity=30.7086614173228, Blast_Score=93, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17565030, Length=276, Percent_Identity=29.7101449275362, Blast_Score=90, Evalue=9e-19, Organism=Caenorhabditis elegans, GI17538486, Length=271, Percent_Identity=28.0442804428044, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17564282, Length=198, Percent_Identity=28.7878787878788, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17508895, Length=195, Percent_Identity=29.2307692307692, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI193203117, Length=198, Percent_Identity=28.7878787878788, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI193203115, Length=193, Percent_Identity=29.5336787564767, Blast_Score=80, Evalue=7e-16, Organism=Caenorhabditis elegans, GI17568967, Length=217, Percent_Identity=32.258064516129, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17508651, Length=259, Percent_Identity=27.4131274131274, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17538182, Length=267, Percent_Identity=26.5917602996255, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17567345, Length=193, Percent_Identity=26.4248704663212, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17561272, Length=173, Percent_Identity=26.0115606936416, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI71982365, Length=192, Percent_Identity=26.5625, Blast_Score=66, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17536025, Length=255, Percent_Identity=21.1764705882353, Blast_Score=65, Evalue=3e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=195, Percent_Identity=30.2564102564103, Blast_Score=81, Evalue=1e-16, Organism=Saccharomyces cerevisiae, GI6323882, Length=198, Percent_Identity=35.3535353535354, Blast_Score=76, Evalue=6e-15, Organism=Saccharomyces cerevisiae, GI6324126, Length=260, Percent_Identity=25.3846153846154, Blast_Score=74, Evalue=2e-14, Organism=Drosophila melanogaster, GI23397609, Length=261, Percent_Identity=35.2490421455939, Blast_Score=124, Evalue=4e-29, Organism=Drosophila melanogaster, GI24639444, Length=256, Percent_Identity=34.375, Blast_Score=119, Evalue=1e-27, Organism=Drosophila melanogaster, GI21355319, Length=259, Percent_Identity=33.2046332046332, Blast_Score=119, Evalue=2e-27, Organism=Drosophila melanogaster, GI21357041, Length=258, Percent_Identity=32.1705426356589, Blast_Score=117, Evalue=6e-27, Organism=Drosophila melanogaster, GI28571526, Length=260, Percent_Identity=33.0769230769231, Blast_Score=114, Evalue=9e-26, Organism=Drosophila melanogaster, GI24644339, Length=263, Percent_Identity=29.6577946768061, Blast_Score=107, Evalue=7e-24, Organism=Drosophila melanogaster, GI24643142, Length=256, Percent_Identity=30.46875, Blast_Score=93, Evalue=2e-19, Organism=Drosophila melanogaster, GI24644337, Length=207, Percent_Identity=31.8840579710145, Blast_Score=88, Evalue=4e-18, Organism=Drosophila melanogaster, GI17737361, Length=268, Percent_Identity=27.9850746268657, Blast_Score=87, Evalue=1e-17, Organism=Drosophila melanogaster, GI281364892, Length=200, Percent_Identity=30.5, Blast_Score=86, Evalue=2e-17, Organism=Drosophila melanogaster, GI24640492, Length=189, Percent_Identity=26.984126984127, Blast_Score=82, Evalue=5e-16, Organism=Drosophila melanogaster, GI221331218, Length=197, Percent_Identity=28.9340101522843, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI24665243, Length=197, Percent_Identity=28.9340101522843, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI221331216, Length=198, Percent_Identity=28.7878787878788, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI24665247, Length=198, Percent_Identity=28.7878787878788, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI18859837, Length=196, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI221510726, Length=201, Percent_Identity=25.8706467661692, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI24665268, Length=223, Percent_Identity=26.457399103139, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI24665264, Length=201, Percent_Identity=27.363184079602, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI21358495, Length=196, Percent_Identity=28.0612244897959, Blast_Score=65, Evalue=3e-11, Organism=Drosophila melanogaster, GI281364494, Length=216, Percent_Identity=25.9259259259259, Blast_Score=65, Evalue=3e-11, Organism=Drosophila melanogaster, GI24649181, Length=189, Percent_Identity=26.4550264550265, Blast_Score=64, Evalue=9e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.14 [H]
Molecular weight: Translated: 27652; Mature: 27652
Theoretical pI: Translated: 5.40; Mature: 5.40
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 3.1 %Met (Translated Protein) 3.9 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 3.1 %Met (Mature Protein) 3.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MRLEDKVAILTGAASGIGEAVAQRYLDEGARCVLVDLKPAGGSLARLIEANPGRAVAVTA CCCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHEECCCCCEEEEEE DVTRRDDIERIVATTVERFGGVDILFNNAALFDMRPILDESWDVFDRLFSVNVKGLFFLM CCCCHHHHHHHHHHHHHHHCCEEEEECCEEEEECCHHHCCHHHHHHHHHHCCHHHHHHHH QAVAQRMVEQGRGGKIVNMSSQAGRRGEALVSHYCATKAAVISYTQSAALALAPHRINVN HHHHHHHHHCCCCCEEEEECHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCEEEEC GIAPGVVDTPMWEQVDALFARYENRPLGEKKRLVGEAVPLGRMGVPGDLTGAALFLASSD CCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCC ADYVTAQTLNVDGGNWMS CCEEEEEEEECCCCCCCC >Mature Secondary Structure MRLEDKVAILTGAASGIGEAVAQRYLDEGARCVLVDLKPAGGSLARLIEANPGRAVAVTA CCCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHEECCCCCEEEEEE DVTRRDDIERIVATTVERFGGVDILFNNAALFDMRPILDESWDVFDRLFSVNVKGLFFLM CCCCHHHHHHHHHHHHHHHCCEEEEECCEEEEECCHHHCCHHHHHHHHHHCCHHHHHHHH QAVAQRMVEQGRGGKIVNMSSQAGRRGEALVSHYCATKAAVISYTQSAALALAPHRINVN HHHHHHHHHCCCCCEEEEECHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCEEEEC GIAPGVVDTPMWEQVDALFARYENRPLGEKKRLVGEAVPLGRMGVPGDLTGAALFLASSD CCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCC ADYVTAQTLNVDGGNWMS CCEEEEEEEECCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 7551049 [H]