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The map label for this gene is polC [H]

Identifier: 78066765

GI number: 78066765

Start: 2349073

End: 2349690

Strand: Direct

Name: polC [H]

Synonym: Bcep18194_A5296

Alternate gene names: 78066765

Gene position: 2349073-2349690 (Clockwise)

Preceding gene: 78066764

Following gene: 78066773

Centisome position: 63.59

GC content: 63.11

Gene sequence:

>618_bases
ATGCAAACCGTTGCGGTACTGGACTTCGAAACAACCGGACTGTCGCCGAATATGGGCGACCGAGCGACCGAAATCGCCGT
CATCCTGCTCCGGGACGGACAAGTCGTCGACCGTTTCCAGAGTCTGATGAATGCAGGCAGACGGATACCGTCGGATGTCG
TCGCGCTGACGGGCATCACGAACGAGATGATCGCAGCGGCGCCGCCGGCGTCGAACGTCATGAAGGAAGCCGCGGCGTTC
GTCGGCAAGCATGCCGTCGTCGCCCACAACGCTGGTTTCGACAAGCGGTTCTGGCAGTCGGAACTCGGGATTCTCGGCAT
GTCGGCCGAGCATGCCTTCGCGTGCACGATGCTCGTGGCGCGACGTATCTACCCGGATGCCCAGAGTCACCGCTTGTCGA
GCCTGGTGGATATGCTGCGGTTGCCCAAATCGGGCCGTGCGCACCGGGCGATGGTCGATGCCGAGATGGCCGGTCACCTG
TGGTGCCGGTTGCAGCACGACATTGCGCGGACTTACGGACTGGATCGCATCGATCACGCGCTCATGACGCGTGTGCAGGC
CACGGCCAAGGCAAAAGTGCCGACGTACCTGCGTTCGCTCGTGGGCTCGCACGCGTGA

Upstream 100 bases:

>100_bases
CGGATGGCCGTTTCCCGGGCTGAACGAGCCTGTCGCGGGCCGGGAGATGCTACCCTCTCGGCCACTCTAACGACACCGCG
TGAAGCAACAGGATTCAACC

Downstream 100 bases:

>100_bases
ATATCCGAGTCGCGATGGTTCTGACTCGCGCAATCCATTGATGCAAAACGGCTTGGCAACCTGCCAAGCCGTTTGCTTGT
CGCGACAGTCTTCCGGTTGA

Product: DNA-directed DNA polymerase

Products: NA

Alternate protein names: PolIII [H]

Number of amino acids: Translated: 205; Mature: 205

Protein sequence:

>205_residues
MQTVAVLDFETTGLSPNMGDRATEIAVILLRDGQVVDRFQSLMNAGRRIPSDVVALTGITNEMIAAAPPASNVMKEAAAF
VGKHAVVAHNAGFDKRFWQSELGILGMSAEHAFACTMLVARRIYPDAQSHRLSSLVDMLRLPKSGRAHRAMVDAEMAGHL
WCRLQHDIARTYGLDRIDHALMTRVQATAKAKVPTYLRSLVGSHA

Sequences:

>Translated_205_residues
MQTVAVLDFETTGLSPNMGDRATEIAVILLRDGQVVDRFQSLMNAGRRIPSDVVALTGITNEMIAAAPPASNVMKEAAAF
VGKHAVVAHNAGFDKRFWQSELGILGMSAEHAFACTMLVARRIYPDAQSHRLSSLVDMLRLPKSGRAHRAMVDAEMAGHL
WCRLQHDIARTYGLDRIDHALMTRVQATAKAKVPTYLRSLVGSHA
>Mature_205_residues
MQTVAVLDFETTGLSPNMGDRATEIAVILLRDGQVVDRFQSLMNAGRRIPSDVVALTGITNEMIAAAPPASNVMKEAAAF
VGKHAVVAHNAGFDKRFWQSELGILGMSAEHAFACTMLVARRIYPDAQSHRLSSLVDMLRLPKSGRAHRAMVDAEMAGHL
WCRLQHDIARTYGLDRIDHALMTRVQATAKAKVPTYLRSLVGSHA

Specific function: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity [H]

COG id: COG2176

COG function: function code L; DNA polymerase III, alpha subunit (gram-positive type)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 exonuclease domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011708
- InterPro:   IPR006054
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR016027
- InterPro:   IPR004365
- InterPro:   IPR004013
- InterPro:   IPR003141
- InterPro:   IPR006308
- InterPro:   IPR012337 [H]

Pfam domain/function: PF07733 DNA_pol3_alpha; PF00929 Exonuc_X-T; PF02811 PHP; PF01336 tRNA_anti [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 22388; Mature: 22388

Theoretical pI: Translated: 9.65; Mature: 9.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTVAVLDFETTGLSPNMGDRATEIAVILLRDGQVVDRFQSLMNAGRRIPSDVVALTGIT
CCEEEEEEEECCCCCCCCCCCCEEEEEEEEECCHHHHHHHHHHHHCCCCCHHHHHHHCCC
NEMIAAAPPASNVMKEAAAFVGKHAVVAHNAGFDKRFWQSELGILGMSAEHAFACTMLVA
HHHHHCCCCHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHCEECCCCHHHHHHHHHHH
RRIYPDAQSHRLSSLVDMLRLPKSGRAHRAMVDAEMAGHLWCRLQHDIARTYGLDRIDHA
HHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
LMTRVQATAKAKVPTYLRSLVGSHA
HHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQTVAVLDFETTGLSPNMGDRATEIAVILLRDGQVVDRFQSLMNAGRRIPSDVVALTGIT
CCEEEEEEEECCCCCCCCCCCCEEEEEEEEECCHHHHHHHHHHHHCCCCCHHHHHHHCCC
NEMIAAAPPASNVMKEAAAFVGKHAVVAHNAGFDKRFWQSELGILGMSAEHAFACTMLVA
HHHHHCCCCHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHCEECCCCHHHHHHHHHHH
RRIYPDAQSHRLSSLVDMLRLPKSGRAHRAMVDAEMAGHLWCRLQHDIARTYGLDRIDHA
HHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
LMTRVQATAKAKVPTYLRSLVGSHA
HHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721630 [H]