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The map label for this gene is mdtP [H]

Identifier: 78066116

GI number: 78066116

Start: 1630970

End: 1632466

Strand: Reverse

Name: mdtP [H]

Synonym: Bcep18194_A4646

Alternate gene names: 78066116

Gene position: 1632466-1630970 (Counterclockwise)

Preceding gene: 78066117

Following gene: 78066115

Centisome position: 44.19

GC content: 68.34

Gene sequence:

>1497_bases
ATGAAATCCTCCCCGTTGTCCGTGCGCGCCGGGTCGTGCCGCGCCGCCGTCGCCGCCGCGGTCGCCGCACTGGCGCTGGC
GGGCTGCGCGAACTACATCGGCATCAAGAGCGACAAGCAGATCGCTCCCGCGTCGCAATTCGAATCCGCCCAGAGCCTGC
CGGCCCAGGGCGGCCAGTGGCCGGCGCTCGACTGGGCCAGCCAGTTCGGCGATCCGCAGCTGCCGAAGCTGATCGACGAG
GCCCTGCAGGGCAATCCGTCGATCGCGCAGGCGCAGGCGCGCATCGCAAAGGCGTCGTCGTACATCGAATCGTCGCGATC
GAGCCTGATGCCGAAGGCGGAAGCCAGCTATTCGTGGACGCGCGAGCTGTATTCGGGGAACGCCCTGTTCCCGCCCCCGT
ACGGCGGCCAGTGGTACAGCGAGAACAACGCACTGGCGAGCGCGTCGTGGGAACTCGACCTGTGGGGCAAGAACCGCGAA
CGCCTGCACACCGCCGTGTCGCAGGAAAAGGCAGCCGAAGCCGACATGCAGCAGGCACGCATCACGCTCGCGTCGTCGGT
CGCACGCACCTACAACTCGCTCGCGCAACTCTATGCGCTGCGCGATATCGCGCAGCGCGAGATCACCAACCGCGAGACGG
TCGGCAAGATCACCGACGGCCGCGTGTCGGCCGGTCTCGACACCAACGTCGAACGCCAGACGGCGCGCGGCAATATCGCG
ACGACCCAGGCTTCGCTGTCGGATCTCGATGGCCAGATCACGACGGTGCGCTACCAGCTCGCCGCGCTGCTCGGCAAGGG
TCCGGATCGCGGGCTGCAGATCGCGGCGCCCGTGCTGAACCCGAGCGGCGAAGTCGCGCTGCCCGGCAACCTGCCGGCCG
ATCTCGTCGCGCGCCGCCCCGACATCGTCGCCGCGCGCTGGCAAGTCGAAGCCGCGATGCACGACGTGAAGGAAGCGAAG
GCCGAGTTCTATCCCGACGTGAACCTCGCGGCCGGCTTCGGCTTCGATGCGTTCGGCTGGGGCAAATTCCTGAACTTCGC
GAGCCGTCAGGCGCAGTTCGGCCCGGCGATCCACCTGCCGATTTTCGACGCCGGCGCGCTGCGCGCGCAGCTCAAGGGCC
GCTATGCGGACTTCGACCTGTCGGTGGCGAACTACAACCAGACGCTGATCAGTGCGCTGAACGACGTCGCGACGCAGGTC
GCGTCGATCCGCGCGGTCGATCGCCAGATGGGCGATGCGCAACGCGCACTCGACGCATCGACGCGCGCCTATGACCTCGC
GGTCATCCGCTACAAGGCCGGCCTGTCGCCGCAGCTGCAGGTGCTGACCGCGGACAGCAACCGCCTCGCATCGGAGCAGA
CGGTGACCAACCTGAAGATGCGCCGCCGCGACATGCAGCTCGCGCTGATCAAGGCGCTGGGTGGCGGGTTCGACGCGACC
GGCACGCCGCTCGCCGCACCCGATGCCGACAAGCCGACAAAACAGGCCGCCAACTGA

Upstream 100 bases:

>100_bases
CAGCATCACGTAATAGTTGCCATAACAATTACTTTTGACAGATTAATGTAAGGAAATCCTTGCAGTGTCCATCATTCATT
CCGAGTCAGGGATCAGCGCG

Downstream 100 bases:

>100_bases
TCCGGCGCCACCACTACGCAGACACTCGAAATAACGGACGGAGAAAATCGCCATGAGCGACCAACAAAACGCCGCCGGCG
CGCAGCCGCAGAACAACGGC

Product: RND efflux system outer membrane lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 498; Mature: 498

Protein sequence:

>498_residues
MKSSPLSVRAGSCRAAVAAAVAALALAGCANYIGIKSDKQIAPASQFESAQSLPAQGGQWPALDWASQFGDPQLPKLIDE
ALQGNPSIAQAQARIAKASSYIESSRSSLMPKAEASYSWTRELYSGNALFPPPYGGQWYSENNALASASWELDLWGKNRE
RLHTAVSQEKAAEADMQQARITLASSVARTYNSLAQLYALRDIAQREITNRETVGKITDGRVSAGLDTNVERQTARGNIA
TTQASLSDLDGQITTVRYQLAALLGKGPDRGLQIAAPVLNPSGEVALPGNLPADLVARRPDIVAARWQVEAAMHDVKEAK
AEFYPDVNLAAGFGFDAFGWGKFLNFASRQAQFGPAIHLPIFDAGALRAQLKGRYADFDLSVANYNQTLISALNDVATQV
ASIRAVDRQMGDAQRALDASTRAYDLAVIRYKAGLSPQLQVLTADSNRLASEQTVTNLKMRRRDMQLALIKALGGGFDAT
GTPLAAPDADKPTKQAAN

Sequences:

>Translated_498_residues
MKSSPLSVRAGSCRAAVAAAVAALALAGCANYIGIKSDKQIAPASQFESAQSLPAQGGQWPALDWASQFGDPQLPKLIDE
ALQGNPSIAQAQARIAKASSYIESSRSSLMPKAEASYSWTRELYSGNALFPPPYGGQWYSENNALASASWELDLWGKNRE
RLHTAVSQEKAAEADMQQARITLASSVARTYNSLAQLYALRDIAQREITNRETVGKITDGRVSAGLDTNVERQTARGNIA
TTQASLSDLDGQITTVRYQLAALLGKGPDRGLQIAAPVLNPSGEVALPGNLPADLVARRPDIVAARWQVEAAMHDVKEAK
AEFYPDVNLAAGFGFDAFGWGKFLNFASRQAQFGPAIHLPIFDAGALRAQLKGRYADFDLSVANYNQTLISALNDVATQV
ASIRAVDRQMGDAQRALDASTRAYDLAVIRYKAGLSPQLQVLTADSNRLASEQTVTNLKMRRRDMQLALIKALGGGFDAT
GTPLAAPDADKPTKQAAN
>Mature_498_residues
MKSSPLSVRAGSCRAAVAAAVAALALAGCANYIGIKSDKQIAPASQFESAQSLPAQGGQWPALDWASQFGDPQLPKLIDE
ALQGNPSIAQAQARIAKASSYIESSRSSLMPKAEASYSWTRELYSGNALFPPPYGGQWYSENNALASASWELDLWGKNRE
RLHTAVSQEKAAEADMQQARITLASSVARTYNSLAQLYALRDIAQREITNRETVGKITDGRVSAGLDTNVERQTARGNIA
TTQASLSDLDGQITTVRYQLAALLGKGPDRGLQIAAPVLNPSGEVALPGNLPADLVARRPDIVAARWQVEAAMHDVKEAK
AEFYPDVNLAAGFGFDAFGWGKFLNFASRQAQFGPAIHLPIFDAGALRAQLKGRYADFDLSVANYNQTLISALNDVATQV
ASIRAVDRQMGDAQRALDASTRAYDLAVIRYKAGLSPQLQVLTADSNRLASEQTVTNLKMRRRDMQLALIKALGGGFDAT
GTPLAAPDADKPTKQAAN

Specific function: Could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI2367348, Length=465, Percent_Identity=31.1827956989247, Blast_Score=198, Evalue=8e-52,
Organism=Escherichia coli, GI1786785, Length=466, Percent_Identity=27.6824034334764, Blast_Score=129, Evalue=5e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 53279; Mature: 53279

Theoretical pI: Translated: 8.86; Mature: 8.86

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSSPLSVRAGSCRAAVAAAVAALALAGCANYIGIKSDKQIAPASQFESAQSLPAQGGQW
CCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCCC
PALDWASQFGDPQLPKLIDEALQGNPSIAQAQARIAKASSYIESSRSSLMPKAEASYSWT
CCHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
RELYSGNALFPPPYGGQWYSENNALASASWELDLWGKNRERLHTAVSQEKAAEADMQQAR
HHHHCCCCCCCCCCCCCCCCCCCCEEECEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
ITLASSVARTYNSLAQLYALRDIAQREITNRETVGKITDGRVSAGLDTNVERQTARGNIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCEECCCCCCCHHHHCCCCCE
TTQASLSDLDGQITTVRYQLAALLGKGPDRGLQIAAPVLNPSGEVALPGNLPADLVARRP
ECHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCEEECCCCCHHHHHCCC
DIVAARWQVEAAMHDVKEAKAEFYPDVNLAAGFGFDAFGWGKFLNFASRQAQFGPAIHLP
CEEEHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCHHHHHHHHHHHHHHHHCCCEEEEE
IFDAGALRAQLKGRYADFDLSVANYNQTLISALNDVATQVASIRAVDRQMGDAQRALDAS
ECCCHHHHHHHCCCCCCEEEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TRAYDLAVIRYKAGLSPQLQVLTADSNRLASEQTVTNLKMRRRDMQLALIKALGGGFDAT
CCCEEEEEEEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GTPLAAPDADKPTKQAAN
CCCCCCCCCCCCHHHCCC
>Mature Secondary Structure
MKSSPLSVRAGSCRAAVAAAVAALALAGCANYIGIKSDKQIAPASQFESAQSLPAQGGQW
CCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCCC
PALDWASQFGDPQLPKLIDEALQGNPSIAQAQARIAKASSYIESSRSSLMPKAEASYSWT
CCHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
RELYSGNALFPPPYGGQWYSENNALASASWELDLWGKNRERLHTAVSQEKAAEADMQQAR
HHHHCCCCCCCCCCCCCCCCCCCCEEECEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
ITLASSVARTYNSLAQLYALRDIAQREITNRETVGKITDGRVSAGLDTNVERQTARGNIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCEECCCCCCCHHHHCCCCCE
TTQASLSDLDGQITTVRYQLAALLGKGPDRGLQIAAPVLNPSGEVALPGNLPADLVARRP
ECHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCEEECCCCCHHHHHCCC
DIVAARWQVEAAMHDVKEAKAEFYPDVNLAAGFGFDAFGWGKFLNFASRQAQFGPAIHLP
CEEEHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCHHHHHHHHHHHHHHHHCCCEEEEE
IFDAGALRAQLKGRYADFDLSVANYNQTLISALNDVATQVASIRAVDRQMGDAQRALDAS
ECCCHHHHHHHCCCCCCEEEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TRAYDLAVIRYKAGLSPQLQVLTADSNRLASEQTVTNLKMRRRDMQLALIKALGGGFDAT
CCCEEEEEEEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GTPLAAPDADKPTKQAAN
CCCCCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]