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The map label for this gene is yybE [H]

Identifier: 78065980

GI number: 78065980

Start: 1474040

End: 1474936

Strand: Reverse

Name: yybE [H]

Synonym: Bcep18194_A4509

Alternate gene names: 78065980

Gene position: 1474936-1474040 (Counterclockwise)

Preceding gene: 78065984

Following gene: 78065977

Centisome position: 39.93

GC content: 72.35

Gene sequence:

>897_bases
ATGGATCTGAATCTTCGCGACATTCGCGCGTTCGTCACCGTCGCGCAGGCCGGCAACTTCACGCGTGCGGCCGCGCGCCT
GCACCTGTCGCAGCCGGCGCTGACCGTGCAGATCCGCCGGCTCGAGGAAATCGTCGGCGCGCGCCTGTTCGACCGCAACA
GCCGCAGCGTCGCGCTCACGCAGACCGGGCGCGAGCTGCTGCCGCTGCTGCAACGCTCGCTCGACGACATGGAGCGTGTG
CTGCGTGACGCGCGCGCGCTCGGCGAAGGCACGAGCGGCACGGTGCGGCTCGCGTGCCTGCCGACCTTCGCGTCCAGCGT
GCTGCCCGAGCTGATCCAGTCGTTCCGGCGCGACGTGCCGCGCGCGGGCTTCGAGATCCGCGACGGCGTCGCGAGCCTCG
TCACCGCGCTCGTGCGCAACGAGGAAGCCGATCTCGGCTTGACCGGCGGCGACACGTTCGATGCGTCGCTGGAGGTGCTG
TATGCGGGCGCCGACCGGCTCGTCGCCGTGTGCCCGAAGGATCATCCGCTCGCGCGCAAGCGCCGCGTGACCACGGCCGA
CGTCGCGGCCGTGCCGCTCGTGCTCACCGCGCGAGGCACGAGCGTGCGCAGCGTCGTCGATGCCGCGCTGGACGCGGCCG
GCTGCACGCCCGACATCGCGTGCGAGCCGACCTACATGATGACGGCGGTCGCGATGGTGCGCGGCGGCCTCGGCGTGACG
ATCCTGCCGGCGACCGCGCGCGAGGTGCGCGCCGAGCCCGAGCTGGTCGCAATGCCGATCGACGACCCCGCGTTCGTGCG
GCCGATCGCGCTCGTCACGAAGCGCGGCCGCACGCTGCCGCGCGTCGCGCAGGCGTTCGCCGAAACCATGCTGATGGAAT
TGAACAGGCGCGCGTGA

Upstream 100 bases:

>100_bases
CATCCGTGTCTCCTACCTTGTCTTTTGTTGGAGACGAGCGTAAGGTCGGCGCAGCGATAGCACAATTGAAATGATTTGAT
CGCAGCAATCACGAACCGTT

Downstream 100 bases:

>100_bases
GCCGCGCGCCCGGATCGGCGGAACCGTCAGCCCGCCCGACGCTTACTTCGCGTCCGGATCGACGTGCAGCGATTCGCCGA
TCGCATAGAAATTTCCGCCT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MDLNLRDIRAFVTVAQAGNFTRAAARLHLSQPALTVQIRRLEEIVGARLFDRNSRSVALTQTGRELLPLLQRSLDDMERV
LRDARALGEGTSGTVRLACLPTFASSVLPELIQSFRRDVPRAGFEIRDGVASLVTALVRNEEADLGLTGGDTFDASLEVL
YAGADRLVAVCPKDHPLARKRRVTTADVAAVPLVLTARGTSVRSVVDAALDAAGCTPDIACEPTYMMTAVAMVRGGLGVT
ILPATAREVRAEPELVAMPIDDPAFVRPIALVTKRGRTLPRVAQAFAETMLMELNRRA

Sequences:

>Translated_298_residues
MDLNLRDIRAFVTVAQAGNFTRAAARLHLSQPALTVQIRRLEEIVGARLFDRNSRSVALTQTGRELLPLLQRSLDDMERV
LRDARALGEGTSGTVRLACLPTFASSVLPELIQSFRRDVPRAGFEIRDGVASLVTALVRNEEADLGLTGGDTFDASLEVL
YAGADRLVAVCPKDHPLARKRRVTTADVAAVPLVLTARGTSVRSVVDAALDAAGCTPDIACEPTYMMTAVAMVRGGLGVT
ILPATAREVRAEPELVAMPIDDPAFVRPIALVTKRGRTLPRVAQAFAETMLMELNRRA
>Mature_298_residues
MDLNLRDIRAFVTVAQAGNFTRAAARLHLSQPALTVQIRRLEEIVGARLFDRNSRSVALTQTGRELLPLLQRSLDDMERV
LRDARALGEGTSGTVRLACLPTFASSVLPELIQSFRRDVPRAGFEIRDGVASLVTALVRNEEADLGLTGGDTFDASLEVL
YAGADRLVAVCPKDHPLARKRRVTTADVAAVPLVLTARGTSVRSVVDAALDAAGCTPDIACEPTYMMTAVAMVRGGLGVT
ILPATAREVRAEPELVAMPIDDPAFVRPIALVTKRGRTLPRVAQAFAETMLMELNRRA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693105, Length=287, Percent_Identity=26.8292682926829, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI1787879, Length=293, Percent_Identity=33.1058020477816, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1788748, Length=292, Percent_Identity=31.8493150684932, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI1788887, Length=248, Percent_Identity=33.8709677419355, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI157672245, Length=286, Percent_Identity=28.6713286713287, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1789204, Length=254, Percent_Identity=31.8897637795276, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI1790399, Length=297, Percent_Identity=29.96632996633, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI87081904, Length=280, Percent_Identity=30, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1787530, Length=264, Percent_Identity=27.6515151515151, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1788481, Length=246, Percent_Identity=28.8617886178862, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1788296, Length=278, Percent_Identity=28.4172661870504, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI2367136, Length=243, Percent_Identity=28.8065843621399, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1790208, Length=253, Percent_Identity=28.8537549407115, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1787589, Length=203, Percent_Identity=31.5270935960591, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1788297, Length=245, Percent_Identity=26.1224489795918, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1790262, Length=256, Percent_Identity=25.390625, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI87082132, Length=270, Percent_Identity=26.2962962962963, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787806, Length=278, Percent_Identity=23.3812949640288, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1787601, Length=182, Percent_Identity=26.3736263736264, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1786508, Length=176, Percent_Identity=26.7045454545455, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1786448, Length=192, Percent_Identity=29.1666666666667, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789639, Length=126, Percent_Identity=27.7777777777778, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1786713, Length=245, Percent_Identity=25.3061224489796, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788626, Length=243, Percent_Identity=25.1028806584362, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32164; Mature: 32164

Theoretical pI: Translated: 8.67; Mature: 8.67

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLNLRDIRAFVTVAQAGNFTRAAARLHLSQPALTVQIRRLEEIVGARLFDRNSRSVALT
CCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEE
QTGRELLPLLQRSLDDMERVLRDARALGEGTSGTVRLACLPTFASSVLPELIQSFRRDVP
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCC
RAGFEIRDGVASLVTALVRNEEADLGLTGGDTFDASLEVLYAGADRLVAVCPKDHPLARK
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCEEEECCCCCCHHHH
RRVTTADVAAVPLVLTARGTSVRSVVDAALDAAGCTPDIACEPTYMMTAVAMVRGGLGVT
HCCCHHHHHHHCEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEE
ILPATAREVRAEPELVAMPIDDPAFVRPIALVTKRGRTLPRVAQAFAETMLMELNRRA
EECCCHHHHCCCCCEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDLNLRDIRAFVTVAQAGNFTRAAARLHLSQPALTVQIRRLEEIVGARLFDRNSRSVALT
CCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEE
QTGRELLPLLQRSLDDMERVLRDARALGEGTSGTVRLACLPTFASSVLPELIQSFRRDVP
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCC
RAGFEIRDGVASLVTALVRNEEADLGLTGGDTFDASLEVLYAGADRLVAVCPKDHPLARK
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCEEEECCCCCCHHHH
RRVTTADVAAVPLVLTARGTSVRSVVDAALDAAGCTPDIACEPTYMMTAVAMVRGGLGVT
HCCCHHHHHHHCEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEE
ILPATAREVRAEPELVAMPIDDPAFVRPIALVTKRGRTLPRVAQAFAETMLMELNRRA
EECCCHHHHCCCCCEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]