| Definition | Burkholderia sp. 383 chromosome 1, complete genome. |
|---|---|
| Accession | NC_007510 |
| Length | 3,694,126 |
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The map label for this gene is cpnA [H]
Identifier: 78065182
GI number: 78065182
Start: 595042
End: 595848
Strand: Direct
Name: cpnA [H]
Synonym: Bcep18194_A3706
Alternate gene names: 78065182
Gene position: 595042-595848 (Clockwise)
Preceding gene: 78065181
Following gene: 78065183
Centisome position: 16.11
GC content: 69.89
Gene sequence:
>807_bases ATGACCATCGACACTTCCGCGCACGACCCGCACGCCGCGAGCCATGCGCGCTATGCACGGTATCCGAGCCTCCAGGATCG CGCGGTGCTGATCACGGGCGGCGCGACCGGCATCGGCGCGGCGTTCGTCGAACACTTCGCCGAACAGGGCGCACGCGTCG CGTTCGTCGACCTCGACGCGGCGGCCGGTACCGCGCTGGCGGACAGCCTCGCGCACGTCCGTCATGCGCCGCTGTTCCTC CAGTGCGACCTGACCGACATCGATGCGCTGCGCCATGCGATCGACGCGATCCGCGCGCGCATCGGCGCGATCGCGGTGCT CGTGAACAACGCGGCGAACGACACGCGCCACGCGATCGGCGACGTGACGCCCGAATCGTTCGACGCGGGCATCGCGGTGA ACCTGCGCCACCAGTTCTTCGCCGCGCAGGCGGTGATCGACGACATGAAGCAGCAGGGCGGCGGCGCGATCATCAATCTC GGCTCGATCAGCTGGATGCTGAAGAACGGCGGCTATCCCGTCTACGTGATGGCGAAGGCCGCCGTGCAGGGGCTGACGCG CGGTCTCGCGCGCGACCTCGGCCCGTTCGGTATCCGCGTGAATTCGCTGGTGCCCGGCTGGGTGATGACCGACAAGCAGC GCCGGCTGTGGCTCGACGACGCGGGCCGCGCGTCGATCAAGGCCGGCCAGTGCCTCGATGCCGAGCTGCTGCCCGCCGAT CTCGCGCGGATGGCGCTGTTCCTCGCGGCCGACGACAGCCGGATGATCACCGCGCAGGACGTGATCGTCGACGGCGGCTG GGCCTGA
Upstream 100 bases:
>100_bases TCGTGCGCGGCGCGATCCTGCTCGCGGCCGTGCTGCTCGACCAGTTGAAGAACCGCGGCGTCCGCGACTGACCCGATCCG CTCTTACGGAGACGAACCGC
Downstream 100 bases:
>100_bases CCGTTCGCACGACCCGCATCGTTTCTTCGACGAAGGAAAGGAGTTCACCATGACCGCCACGTCCTCGCGCGCATCGTCGT CCACCAGCCAGTCGCGCCGC
Product: Short-chain dehydrogenase/reductase SDR
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 268; Mature: 267
Protein sequence:
>268_residues MTIDTSAHDPHAASHARYARYPSLQDRAVLITGGATGIGAAFVEHFAEQGARVAFVDLDAAAGTALADSLAHVRHAPLFL QCDLTDIDALRHAIDAIRARIGAIAVLVNNAANDTRHAIGDVTPESFDAGIAVNLRHQFFAAQAVIDDMKQQGGGAIINL GSISWMLKNGGYPVYVMAKAAVQGLTRGLARDLGPFGIRVNSLVPGWVMTDKQRRLWLDDAGRASIKAGQCLDAELLPAD LARMALFLAADDSRMITAQDVIVDGGWA
Sequences:
>Translated_268_residues MTIDTSAHDPHAASHARYARYPSLQDRAVLITGGATGIGAAFVEHFAEQGARVAFVDLDAAAGTALADSLAHVRHAPLFL QCDLTDIDALRHAIDAIRARIGAIAVLVNNAANDTRHAIGDVTPESFDAGIAVNLRHQFFAAQAVIDDMKQQGGGAIINL GSISWMLKNGGYPVYVMAKAAVQGLTRGLARDLGPFGIRVNSLVPGWVMTDKQRRLWLDDAGRASIKAGQCLDAELLPAD LARMALFLAADDSRMITAQDVIVDGGWA >Mature_267_residues TIDTSAHDPHAASHARYARYPSLQDRAVLITGGATGIGAAFVEHFAEQGARVAFVDLDAAAGTALADSLAHVRHAPLFLQ CDLTDIDALRHAIDAIRARIGAIAVLVNNAANDTRHAIGDVTPESFDAGIAVNLRHQFFAAQAVIDDMKQQGGGAIINLG SISWMLKNGGYPVYVMAKAAVQGLTRGLARDLGPFGIRVNSLVPGWVMTDKQRRLWLDDAGRASIKAGQCLDAELLPADL ARMALFLAADDSRMITAQDVIVDGGWA
Specific function: Reduces cyclopentanol to cyclopentanone. The enzyme also shows considerable activity toward cyclohexanol [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI32483357, Length=266, Percent_Identity=31.5789473684211, Blast_Score=114, Evalue=7e-26, Organism=Homo sapiens, GI15277342, Length=256, Percent_Identity=32.8125, Blast_Score=97, Evalue=2e-20, Organism=Homo sapiens, GI7705925, Length=253, Percent_Identity=33.9920948616601, Blast_Score=93, Evalue=3e-19, Organism=Homo sapiens, GI31542939, Length=191, Percent_Identity=32.4607329842932, Blast_Score=91, Evalue=9e-19, Organism=Homo sapiens, GI40254992, Length=247, Percent_Identity=28.7449392712551, Blast_Score=89, Evalue=3e-18, Organism=Homo sapiens, GI19923817, Length=256, Percent_Identity=26.5625, Blast_Score=89, Evalue=3e-18, Organism=Homo sapiens, GI126723750, Length=257, Percent_Identity=25.6809338521401, Blast_Score=87, Evalue=2e-17, Organism=Homo sapiens, GI59889578, Length=233, Percent_Identity=28.3261802575107, Blast_Score=84, Evalue=2e-16, Organism=Homo sapiens, GI66933014, Length=232, Percent_Identity=28.8793103448276, Blast_Score=80, Evalue=3e-15, Organism=Homo sapiens, GI10190704, Length=250, Percent_Identity=29.2, Blast_Score=78, Evalue=9e-15, Organism=Homo sapiens, GI224922801, Length=169, Percent_Identity=31.3609467455621, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI4758504, Length=200, Percent_Identity=33, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI126723191, Length=223, Percent_Identity=28.2511210762332, Blast_Score=73, Evalue=2e-13, Organism=Homo sapiens, GI302344755, Length=126, Percent_Identity=33.3333333333333, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI83715985, Length=188, Percent_Identity=31.9148936170213, Blast_Score=65, Evalue=4e-11, Organism=Escherichia coli, GI1787335, Length=247, Percent_Identity=31.5789473684211, Blast_Score=106, Evalue=2e-24, Organism=Escherichia coli, GI87082100, Length=251, Percent_Identity=29.0836653386454, Blast_Score=97, Evalue=7e-22, Organism=Escherichia coli, GI1790717, Length=244, Percent_Identity=29.5081967213115, Blast_Score=97, Evalue=9e-22, Organism=Escherichia coli, GI1789208, Length=246, Percent_Identity=29.2682926829268, Blast_Score=97, Evalue=1e-21, Organism=Escherichia coli, GI1787905, Length=256, Percent_Identity=29.296875, Blast_Score=92, Evalue=4e-20, Organism=Escherichia coli, GI87082160, Length=258, Percent_Identity=29.4573643410853, Blast_Score=89, Evalue=3e-19, Organism=Escherichia coli, GI1786812, Length=248, Percent_Identity=29.4354838709677, Blast_Score=85, Evalue=5e-18, Organism=Escherichia coli, GI2367365, Length=246, Percent_Identity=29.6747967479675, Blast_Score=79, Evalue=4e-16, Organism=Escherichia coli, GI1789378, Length=253, Percent_Identity=28.0632411067194, Blast_Score=77, Evalue=2e-15, Organism=Escherichia coli, GI2367175, Length=188, Percent_Identity=30.3191489361702, Blast_Score=71, Evalue=7e-14, Organism=Escherichia coli, GI1788459, Length=246, Percent_Identity=27.6422764227642, Blast_Score=68, Evalue=6e-13, Organism=Escherichia coli, GI1788891, Length=194, Percent_Identity=30.4123711340206, Blast_Score=64, Evalue=1e-11, Organism=Caenorhabditis elegans, GI115534694, Length=246, Percent_Identity=30.8943089430894, Blast_Score=102, Evalue=1e-22, Organism=Caenorhabditis elegans, GI25147288, Length=250, Percent_Identity=30.4, Blast_Score=97, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17555706, Length=246, Percent_Identity=28.0487804878049, Blast_Score=88, Evalue=6e-18, Organism=Caenorhabditis elegans, GI72000259, Length=266, Percent_Identity=29.6992481203008, Blast_Score=87, Evalue=7e-18, Organism=Caenorhabditis elegans, GI17561402, Length=251, Percent_Identity=27.4900398406374, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17562904, Length=272, Percent_Identity=29.7794117647059, Blast_Score=81, Evalue=7e-16, Organism=Caenorhabditis elegans, GI17559104, Length=267, Percent_Identity=28.4644194756554, Blast_Score=80, Evalue=9e-16, Organism=Caenorhabditis elegans, GI17567345, Length=190, Percent_Identity=27.8947368421053, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI71994600, Length=246, Percent_Identity=26.4227642276423, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17563726, Length=262, Percent_Identity=28.2442748091603, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17560332, Length=272, Percent_Identity=29.0441176470588, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI71994604, Length=244, Percent_Identity=26.2295081967213, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17560150, Length=265, Percent_Identity=27.5471698113208, Blast_Score=74, Evalue=8e-14, Organism=Caenorhabditis elegans, GI17560676, Length=254, Percent_Identity=25.1968503937008, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI193204405, Length=271, Percent_Identity=29.1512915129151, Blast_Score=70, Evalue=8e-13, Organism=Caenorhabditis elegans, GI17562910, Length=276, Percent_Identity=25.3623188405797, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17560220, Length=268, Percent_Identity=29.1044776119403, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17508651, Length=245, Percent_Identity=25.7142857142857, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17562906, Length=263, Percent_Identity=26.615969581749, Blast_Score=68, Evalue=6e-12, Organism=Caenorhabditis elegans, GI17562908, Length=263, Percent_Identity=26.615969581749, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17538480, Length=266, Percent_Identity=27.0676691729323, Blast_Score=65, Evalue=3e-11, Organism=Caenorhabditis elegans, GI17531453, Length=270, Percent_Identity=27.037037037037, Blast_Score=64, Evalue=5e-11, Organism=Caenorhabditis elegans, GI17562990, Length=273, Percent_Identity=27.1062271062271, Blast_Score=64, Evalue=9e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=190, Percent_Identity=27.3684210526316, Blast_Score=68, Evalue=1e-12, Organism=Drosophila melanogaster, GI28571526, Length=250, Percent_Identity=30.4, Blast_Score=100, Evalue=1e-21, Organism=Drosophila melanogaster, GI21357041, Length=250, Percent_Identity=30, Blast_Score=97, Evalue=8e-21, Organism=Drosophila melanogaster, GI24643142, Length=246, Percent_Identity=29.2682926829268, Blast_Score=92, Evalue=3e-19, Organism=Drosophila melanogaster, GI23397609, Length=199, Percent_Identity=33.1658291457286, Blast_Score=92, Evalue=3e-19, Organism=Drosophila melanogaster, GI24639444, Length=248, Percent_Identity=28.6290322580645, Blast_Score=87, Evalue=8e-18, Organism=Drosophila melanogaster, GI21355319, Length=260, Percent_Identity=26.9230769230769, Blast_Score=87, Evalue=1e-17, Organism=Drosophila melanogaster, GI281364892, Length=182, Percent_Identity=30.7692307692308, Blast_Score=82, Evalue=4e-16, Organism=Drosophila melanogaster, GI24644337, Length=245, Percent_Identity=30.2040816326531, Blast_Score=78, Evalue=5e-15, Organism=Drosophila melanogaster, GI24644339, Length=246, Percent_Identity=27.6422764227642, Blast_Score=75, Evalue=5e-14, Organism=Drosophila melanogaster, GI17737361, Length=199, Percent_Identity=29.1457286432161, Blast_Score=68, Evalue=5e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.163 [H]
Molecular weight: Translated: 28416; Mature: 28284
Theoretical pI: Translated: 6.23; Mature: 6.23
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.7 %Cys (Translated Protein) 2.6 %Met (Translated Protein) 3.4 %Cys+Met (Translated Protein) 0.7 %Cys (Mature Protein) 2.2 %Met (Mature Protein) 3.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTIDTSAHDPHAASHARYARYPSLQDRAVLITGGATGIGAAFVEHFAEQGARVAFVDLDA CCCCCCCCCCCCHHCCHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCC AAGTALADSLAHVRHAPLFLQCDLTDIDALRHAIDAIRARIGAIAVLVNNAANDTRHAIG CCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHEEEEEEECCCCCHHHHHC DVTPESFDAGIAVNLRHQFFAAQAVIDDMKQQGGGAIINLGSISWMLKNGGYPVYVMAKA CCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCEEEEECCEEEEEECCCCEEEEEHHH AVQGLTRGLARDLGPFGIRVNSLVPGWVMTDKQRRLWLDDAGRASIKAGQCLDAELLPAD HHHHHHHHHHHCCCCCCEEECCCCCCEEEECCCCEEEECCCCCCCCCCCCCCCCCCCHHH LARMALFLAADDSRMITAQDVIVDGGWA HHHHEEEEECCCCCEEEEEEEEECCCCC >Mature Secondary Structure TIDTSAHDPHAASHARYARYPSLQDRAVLITGGATGIGAAFVEHFAEQGARVAFVDLDA CCCCCCCCCCCHHCCHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCC AAGTALADSLAHVRHAPLFLQCDLTDIDALRHAIDAIRARIGAIAVLVNNAANDTRHAIG CCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHEEEEEEECCCCCHHHHHC DVTPESFDAGIAVNLRHQFFAAQAVIDDMKQQGGGAIINLGSISWMLKNGGYPVYVMAKA CCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCEEEEECCEEEEEECCCCEEEEEHHH AVQGLTRGLARDLGPFGIRVNSLVPGWVMTDKQRRLWLDDAGRASIKAGQCLDAELLPAD HHHHHHHHHHHCCCCCCEEECCCCCCEEEECCCCEEEECCCCCCCCCCCCCCCCCCCHHH LARMALFLAADDSRMITAQDVIVDGGWA HHHHEEEEECCCCCEEEEEEEEECCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 12406764 [H]