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The map label for this gene is engD [H]

Identifier: 78065087

GI number: 78065087

Start: 484708

End: 485802

Strand: Reverse

Name: engD [H]

Synonym: Bcep18194_A3611

Alternate gene names: 78065087

Gene position: 485802-484708 (Counterclockwise)

Preceding gene: 78065092

Following gene: 78065082

Centisome position: 13.15

GC content: 64.2

Gene sequence:

>1095_bases
ATGAGTCTCAAATGCGGCATCGTCGGCTTGCCCAACGTCGGCAAGTCCACCCTGTTCAATGCGCTGACCAAGGCCGGCAT
CGCCGCCGAGAACTACCCGTTCTGCACGATCGAGCCGAACGTCGGCATCGTCGAAGTGCCCGATACGCGCCTGAAGGCGC
TCTCCGAGATCGTCAAGCCGGAGCGTGTCGTGCCGGCCGTCGTCGAATTCGTCGACATCGCGGGCCTCGTCGCGGGCGCG
AGCAAGGGTGAAGGCCTCGGCAACCAGTTCCTCGCGAACATCCGCGAAACCGACGCGATCACGCACGTCGTGCGCTGCTT
CGAAGACGAGAACGTCATTCACGTCGCCGGCAAGGTCAGCCCGATCGACGACATCGAAGTGATCAACACGGAACTCGCGC
TCGCCGACCTCGGCACCGTCGAGAAGGCGCTCACGCGTTATTCGAAGGCGGCGAAGTCGGGCAACGACAAGGAAGCGGGC
AAGCTCGTCGCCGTGCTCGAGAAGGTGCGCGCGCAACTCGACCAGGGCAAGGCCGTGCGCGGCCTCACGCTGTCGGACGA
CGAAGAGGCGCTGCTCAAGCCGTTCTGCCTGATTACCGCGAAGCCGACGATGTATGTCGCCAACGTGAAGGACGACGGTT
TCGAGAACAACCCGCACCTCGACGCGGTCCGCAAGTACGCGGAAAGCGAGAATGCGCCGGTCGTGGCCGTGTGCGCGGCG
ATCGAGGCGGAAATCGCCGATCTCGACGATGCGGACAAGGAAGCGTTCCTCGCCGACATGGGCATGCAGGAGCCGGGCCT
CGACCGCGTGATCCGCGCGGGCTTCAAGCTGCTCGGCCTGCAGACCTACTTCACCGCGGGTGTGAAGGAAGTCCGTGCGT
GGACGATCCATATCGGCGACACGGCACCGCAGGCGGCCGGCGTGATCCACACCGACTTCGAGCGCGGCTTCATCCGCGCG
CAGACGATCGCGTTCGACGACTACGTCACGTTCAAGGGCGAGCAAGGCGCGAAGGAAGCCGGCAAGATGCGCGCGGAAGG
GAAGGAATATGTCGTGCACGACGGCGACGTGATGAACTTCCTGTTCAACGTCTGA

Upstream 100 bases:

>100_bases
TTTGACCGTCGGCCCGCCGCGCCCCAAGCGCCGGCCGCCCTTTTTTCCCGCGCCGCCGTGCCCTGTCCGGCCGCGCCGCC
TTACCCGTCCGAAGGATTCC

Downstream 100 bases:

>100_bases
GCGTCGCGTTATCGTCTCAGTGAAAAGCCCGCTTATGCGGGCTTTTTTCTTTTCGGTGCACCGGCCTTGTCATGACTGGC
TCCGATGACCGGATTTCGAT

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 364; Mature: 363

Protein sequence:

>364_residues
MSLKCGIVGLPNVGKSTLFNALTKAGIAAENYPFCTIEPNVGIVEVPDTRLKALSEIVKPERVVPAVVEFVDIAGLVAGA
SKGEGLGNQFLANIRETDAITHVVRCFEDENVIHVAGKVSPIDDIEVINTELALADLGTVEKALTRYSKAAKSGNDKEAG
KLVAVLEKVRAQLDQGKAVRGLTLSDDEEALLKPFCLITAKPTMYVANVKDDGFENNPHLDAVRKYAESENAPVVAVCAA
IEAEIADLDDADKEAFLADMGMQEPGLDRVIRAGFKLLGLQTYFTAGVKEVRAWTIHIGDTAPQAAGVIHTDFERGFIRA
QTIAFDDYVTFKGEQGAKEAGKMRAEGKEYVVHDGDVMNFLFNV

Sequences:

>Translated_364_residues
MSLKCGIVGLPNVGKSTLFNALTKAGIAAENYPFCTIEPNVGIVEVPDTRLKALSEIVKPERVVPAVVEFVDIAGLVAGA
SKGEGLGNQFLANIRETDAITHVVRCFEDENVIHVAGKVSPIDDIEVINTELALADLGTVEKALTRYSKAAKSGNDKEAG
KLVAVLEKVRAQLDQGKAVRGLTLSDDEEALLKPFCLITAKPTMYVANVKDDGFENNPHLDAVRKYAESENAPVVAVCAA
IEAEIADLDDADKEAFLADMGMQEPGLDRVIRAGFKLLGLQTYFTAGVKEVRAWTIHIGDTAPQAAGVIHTDFERGFIRA
QTIAFDDYVTFKGEQGAKEAGKMRAEGKEYVVHDGDVMNFLFNV
>Mature_363_residues
SLKCGIVGLPNVGKSTLFNALTKAGIAAENYPFCTIEPNVGIVEVPDTRLKALSEIVKPERVVPAVVEFVDIAGLVAGAS
KGEGLGNQFLANIRETDAITHVVRCFEDENVIHVAGKVSPIDDIEVINTELALADLGTVEKALTRYSKAAKSGNDKEAGK
LVAVLEKVRAQLDQGKAVRGLTLSDDEEALLKPFCLITAKPTMYVANVKDDGFENNPHLDAVRKYAESENAPVVAVCAAI
EAEIADLDDADKEAFLADMGMQEPGLDRVIRAGFKLLGLQTYFTAGVKEVRAWTIHIGDTAPQAAGVIHTDFERGFIRAQ
TIAFDDYVTFKGEQGAKEAGKMRAEGKEYVVHDGDVMNFLFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=369, Percent_Identity=42.5474254742547, Blast_Score=296, Evalue=2e-80,
Organism=Homo sapiens, GI58761502, Length=227, Percent_Identity=35.2422907488987, Blast_Score=143, Evalue=3e-34,
Organism=Escherichia coli, GI1787454, Length=364, Percent_Identity=69.7802197802198, Blast_Score=531, Evalue=1e-152,
Organism=Escherichia coli, GI1789574, Length=141, Percent_Identity=29.0780141843972, Blast_Score=61, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17509631, Length=366, Percent_Identity=40.7103825136612, Blast_Score=288, Evalue=3e-78,
Organism=Saccharomyces cerevisiae, GI6319499, Length=369, Percent_Identity=39.2953929539295, Blast_Score=248, Evalue=1e-66,
Organism=Saccharomyces cerevisiae, GI6321773, Length=380, Percent_Identity=34.4736842105263, Blast_Score=199, Evalue=7e-52,
Organism=Saccharomyces cerevisiae, GI6321649, Length=206, Percent_Identity=34.4660194174757, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24640873, Length=367, Percent_Identity=41.6893732970027, Blast_Score=288, Evalue=3e-78,
Organism=Drosophila melanogaster, GI24640877, Length=367, Percent_Identity=41.6893732970027, Blast_Score=288, Evalue=3e-78,
Organism=Drosophila melanogaster, GI24640875, Length=367, Percent_Identity=41.6893732970027, Blast_Score=288, Evalue=3e-78,
Organism=Drosophila melanogaster, GI24640879, Length=325, Percent_Identity=39.0769230769231, Blast_Score=230, Evalue=9e-61,
Organism=Drosophila melanogaster, GI24585318, Length=144, Percent_Identity=30.5555555555556, Blast_Score=68, Evalue=9e-12,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 39194; Mature: 39063

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLKCGIVGLPNVGKSTLFNALTKAGIAAENYPFCTIEPNVGIVEVPDTRLKALSEIVKP
CCCEECEEECCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCEEECCCHHHHHHHHHHCC
ERVVPAVVEFVDIAGLVAGASKGEGLGNQFLANIRETDAITHVVRCFEDENVIHVAGKVS
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
PIDDIEVINTELALADLGTVEKALTRYSKAAKSGNDKEAGKLVAVLEKVRAQLDQGKAVR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCEEE
GLTLSDDEEALLKPFCLITAKPTMYVANVKDDGFENNPHLDAVRKYAESENAPVVAVCAA
CCCCCCCHHHHHCCEEEEEECCEEEEEECCCCCCCCCCCHHHHHHHHCCCCCCEEEEEHH
IEAEIADLDDADKEAFLADMGMQEPGLDRVIRAGFKLLGLQTYFTAGVKEVRAWTIHIGD
HHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECC
TAPQAAGVIHTDFERGFIRAQTIAFDDYVTFKGEQGAKEAGKMRAEGKEYVVHDGDVMNF
CCCCCCCCEEECCCCCEEEEEEEEEECEEEECCCCCCHHHHHHHCCCCEEEEECCHHHHH
LFNV
HHCC
>Mature Secondary Structure 
SLKCGIVGLPNVGKSTLFNALTKAGIAAENYPFCTIEPNVGIVEVPDTRLKALSEIVKP
CCEECEEECCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCEEECCCHHHHHHHHHHCC
ERVVPAVVEFVDIAGLVAGASKGEGLGNQFLANIRETDAITHVVRCFEDENVIHVAGKVS
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
PIDDIEVINTELALADLGTVEKALTRYSKAAKSGNDKEAGKLVAVLEKVRAQLDQGKAVR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCEEE
GLTLSDDEEALLKPFCLITAKPTMYVANVKDDGFENNPHLDAVRKYAESENAPVVAVCAA
CCCCCCCHHHHHCCEEEEEECCEEEEEECCCCCCCCCCCHHHHHHHHCCCCCCEEEEEHH
IEAEIADLDDADKEAFLADMGMQEPGLDRVIRAGFKLLGLQTYFTAGVKEVRAWTIHIGD
HHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECC
TAPQAAGVIHTDFERGFIRAQTIAFDDYVTFKGEQGAKEAGKMRAEGKEYVVHDGDVMNF
CCCCCCCCEEECCCCCEEEEEEEEEECEEEECCCCCCHHHHHHHCCCCEEEEECCHHHHH
LFNV
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]