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The map label for this gene is ung [H]

Identifier: 78065092

GI number: 78065092

Start: 490813

End: 491718

Strand: Reverse

Name: ung [H]

Synonym: Bcep18194_A3616

Alternate gene names: 78065092

Gene position: 491718-490813 (Counterclockwise)

Preceding gene: 78065093

Following gene: 78065087

Centisome position: 13.31

GC content: 71.08

Gene sequence:

>906_bases
ATGGCAACCCGCAAGACTCCCCGCGCGCCGCAACAGGCGTCGCTGTTCGACGATCCCGTGCCGGAAACGGCACCGGCCGA
TATTCCGTCCCCGGCGCCCGACGCGCCCGCGGCCGGACGCAAGCCCGCAAAGAAAGCCGCTGCTCCGGCTGCGGCCCCGA
CGGCGCCACAGCCCGCTGCCGCCGACGTTCCGCACCTCGCCGCGCAATTCGACGCGCTGCCGACCGTCTGGCGCGACGTG
CTGAAGCCCTTTACCGACAGCGACGCGTACGCGCCGCTGTGTCGCTTCGTCGATGACGAGCGTGCGGCCGGCAAGACGGT
CTACCCGACCGACGTGTTCCGCGCGCTGCGCCTGACGAGCCCGGACGACGTCAAAGTCGTGATCCTCGGCCAGGATCCGT
ACCACGGCGACGATCGCGGCACGCCGCAGGCGCACGGGCTCGCGTTCTCGGTGCCGCCGGCCGTGCGCACCCCGCCGTCG
CTGCGCAACATCTTCAAGGAAATCGCCGCGAACTTCGGTCATGACACGCCGCGCCACGGCTGCCTCGACACCTGGGCACG
CCAGGGCGTGCTGCTGCTCAACACGGTGCTCACGGTCGAGCGCGGTGCCGCAGCGAGCCATGCGAAGCGCGGCTGGGAGC
AGTGCACGGACACGCTGATCCGCGAACTCGCCGGCCGCCATCGCGGGCTCGTCTTCATGCTGTGGGGCGCACACGCGCAG
GCGAAGCGCGCGCTGTTCGACGCGAGCGCGCACTGCGTGCTCGAGGCGCCGCATCCGTCGCCGCTGTCCGCGCACCGTGG
CTTCCTCGGCTGCCGCCATTTCGCGCTCGCGAACGACTATCTGGTCGAGGCAGACCGCGAACCGATCGACTGGCGCCTGC
CGGAAGTGGCCGAAACGCTCGCATAG

Upstream 100 bases:

>100_bases
CGCCGCCGAACTGCAGCAAGCGCTGCCGGGCCTCGCTCCCGACAACATCAGCAAGGCGCAGCGCGGCTACCGGCTGCGCG
CGCAATAACCCGCATCACGC

Downstream 100 bases:

>100_bases
CGGCCGCGCCGCCGATTCTTTCGGCCACGCCAGCCGGCATGCAAAAACGCCGCGCCCCTTTCGGGACGCGGCGTTTTTTT
ATCGGGCGATGCTGCGGGTG

Product: uracil-DNA glycosylase

Products: NA

Alternate protein names: UDG [H]

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MATRKTPRAPQQASLFDDPVPETAPADIPSPAPDAPAAGRKPAKKAAAPAAAPTAPQPAAADVPHLAAQFDALPTVWRDV
LKPFTDSDAYAPLCRFVDDERAAGKTVYPTDVFRALRLTSPDDVKVVILGQDPYHGDDRGTPQAHGLAFSVPPAVRTPPS
LRNIFKEIAANFGHDTPRHGCLDTWARQGVLLLNTVLTVERGAAASHAKRGWEQCTDTLIRELAGRHRGLVFMLWGAHAQ
AKRALFDASAHCVLEAPHPSPLSAHRGFLGCRHFALANDYLVEADREPIDWRLPEVAETLA

Sequences:

>Translated_301_residues
MATRKTPRAPQQASLFDDPVPETAPADIPSPAPDAPAAGRKPAKKAAAPAAAPTAPQPAAADVPHLAAQFDALPTVWRDV
LKPFTDSDAYAPLCRFVDDERAAGKTVYPTDVFRALRLTSPDDVKVVILGQDPYHGDDRGTPQAHGLAFSVPPAVRTPPS
LRNIFKEIAANFGHDTPRHGCLDTWARQGVLLLNTVLTVERGAAASHAKRGWEQCTDTLIRELAGRHRGLVFMLWGAHAQ
AKRALFDASAHCVLEAPHPSPLSAHRGFLGCRHFALANDYLVEADREPIDWRLPEVAETLA
>Mature_300_residues
ATRKTPRAPQQASLFDDPVPETAPADIPSPAPDAPAAGRKPAKKAAAPAAAPTAPQPAAADVPHLAAQFDALPTVWRDVL
KPFTDSDAYAPLCRFVDDERAAGKTVYPTDVFRALRLTSPDDVKVVILGQDPYHGDDRGTPQAHGLAFSVPPAVRTPPSL
RNIFKEIAANFGHDTPRHGCLDTWARQGVLLLNTVLTVERGAAASHAKRGWEQCTDTLIRELAGRHRGLVFMLWGAHAQA
KRALFDASAHCVLEAPHPSPLSAHRGFLGCRHFALANDYLVEADREPIDWRLPEVAETLA

Specific function: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine [H]

COG id: COG0692

COG function: function code L; Uracil DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uracil-DNA glycosylase family [H]

Homologues:

Organism=Homo sapiens, GI19718751, Length=221, Percent_Identity=48.868778280543, Blast_Score=198, Evalue=4e-51,
Organism=Homo sapiens, GI6224979, Length=221, Percent_Identity=48.868778280543, Blast_Score=197, Evalue=1e-50,
Organism=Escherichia coli, GI1788934, Length=218, Percent_Identity=54.5871559633027, Blast_Score=234, Evalue=6e-63,
Organism=Caenorhabditis elegans, GI17556304, Length=219, Percent_Identity=42.9223744292237, Blast_Score=184, Evalue=4e-47,
Organism=Saccharomyces cerevisiae, GI6323620, Length=250, Percent_Identity=41.2, Blast_Score=158, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002043
- InterPro:   IPR018085
- InterPro:   IPR005122 [H]

Pfam domain/function: PF03167 UDG [H]

EC number: =3.2.2.27 [H]

Molecular weight: Translated: 32483; Mature: 32352

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: PS00130 U_DNA_GLYCOSYLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATRKTPRAPQQASLFDDPVPETAPADIPSPAPDAPAAGRKPAKKAAAPAAAPTAPQPAA
CCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCC
ADVPHLAAQFDALPTVWRDVLKPFTDSDAYAPLCRFVDDERAAGKTVYPTDVFRALRLTS
CCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHCCCCCCCHHHHHHHHHCCC
PDDVKVVILGQDPYHGDDRGTPQAHGLAFSVPPAVRTPPSLRNIFKEIAANFGHDTPRHG
CCCEEEEEECCCCCCCCCCCCCHHCCEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCH
CLDTWARQGVLLLNTVLTVERGAAASHAKRGWEQCTDTLIRELAGRHRGLVFMLWGAHAQ
HHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHH
AKRALFDASAHCVLEAPHPSPLSAHRGFLGCRHFALANDYLVEADREPIDWRLPEVAETL
HHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCHHEECCCCCCCCCCHHHHHHC
A
C
>Mature Secondary Structure 
ATRKTPRAPQQASLFDDPVPETAPADIPSPAPDAPAAGRKPAKKAAAPAAAPTAPQPAA
CCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCC
ADVPHLAAQFDALPTVWRDVLKPFTDSDAYAPLCRFVDDERAAGKTVYPTDVFRALRLTS
CCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHCCCCCCCHHHHHHHHHCCC
PDDVKVVILGQDPYHGDDRGTPQAHGLAFSVPPAVRTPPSLRNIFKEIAANFGHDTPRHG
CCCEEEEEECCCCCCCCCCCCCHHCCEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCH
CLDTWARQGVLLLNTVLTVERGAAASHAKRGWEQCTDTLIRELAGRHRGLVFMLWGAHAQ
HHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHH
AKRALFDASAHCVLEAPHPSPLSAHRGFLGCRHFALANDYLVEADREPIDWRLPEVAETL
HHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCHHEECCCCCCCCCCHHHHHHC
A
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA