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The map label for this gene is pncB [H]

Identifier: 78049203

GI number: 78049203

Start: 4198243

End: 4199421

Strand: Reverse

Name: pncB [H]

Synonym: XCV3647

Alternate gene names: 78049203

Gene position: 4199421-4198243 (Counterclockwise)

Preceding gene: 78049204

Following gene: 78049202

Centisome position: 81.09

GC content: 63.95

Gene sequence:

>1179_bases
ATGATCATCCATTCGCTGCTCGACACCGACCTGTACAAATTCACCATGATGCAGGCAGTGCTGCACCAGCACCCGGCAGC
GCAGGTGGATTACCGCTTCAAGTGCCGCACCCCCGGCGTGGATCTGGCGCAGTTCGTCGATGAGATCTCGCGCGAGATCG
ATGCGCTGTGCCGGTTGCGGCTGCGCGAGGACGAAGTGGATTACCTGCGCAGCCTGCGCTTCATCAAGCCGGACTTCGCC
GACTTCCTGGCGCTGTTCCATCTGGATCGCAAGTATCTGAGCCTGACCGCATCGGCCACCCATCCGGGCGAGATCGAGCT
GACCATCCGCGGCCCCTGGCTGCACACCATCCTGTTCGAGGTGCCGCTGCTGGCGATCATCAACGAGGTGTGGTTTCGCA
ATACCTCCGAGCCGGATTTCGAAGAGGGCCGCAGCCGCCTGCGCGAGAAGGTGGCGAGCCTGCGCAGCATGCCGGCCGGC
TGCAAGATCGCCGACTACGGCACCCGGCGGCGCTACTCGCGGCAATGGCATGGCGAGTTGCTGCCGCTGCTGCGCGATGG
CCTGGGCGAACAGTTCGTCGGCACCAGTAACGTGTATTTCGCCAAGCAGTACGGGCTGACCCCGCTGGGCACGATGGCGC
ACGAGTATCTGCAGGCGTTCCAGGCGTTGGGGCCGCGGCTGCGCGATTCGCAGGTGGCGGCGCTGGAATCGTGGGCGCGC
GAATACCGTGGCGATCTGGGCATTGCGTTGTCGGACGTGGTTGGGCTGGATGCGTTCCTGCGCGATTTCGATCTGTATTT
CTGCAAGTTGTTCGATGGCATGCGCCACGATTCGGGTGACCCGTTCGAATGGGGCGAGCGCGTCATCGCGCATCTGGAAG
CGCACCGCGTCGATCCCCGGACCAAGGTGCTGGTGTTCAGCGACGGGCTCAATATCGACAAGGTGATGCGGCTGTACCAG
CACTTCCACACGCGCTGCCGGCTGGCCTTCGGGGTGGGCACCAGCCTGACCAACGATCTGGGGCCGACGCCGCTGCAGAT
CGTGATCAAAATGGTCCGCTGCAATGGCCAGCCGGTGGCCAAGCTCAGCGACTCGCCCGGCAAGAGCATGTGCGAGGACA
TCGGGTATCTGCGCTATCTGCGCGACGTGTTCGGACTGCCGCCGATGGCAGAGGGATGA

Upstream 100 bases:

>100_bases
CAATCGCGGCTGTCTACCTGACGACACAGGTGCGCTGCGTTCTCACGCGGCTTGCGCACTGCACGCGCTGTCATCGCCGC
CAAGGGCATAATCCGGCGGC

Downstream 100 bases:

>100_bases
TCGCTCGGGGCGATGCCGGCGGGGACTGACGGGCGGGCGTCGCCACCCGCTACAGAAATTCCCTACACGCTGTCGGGGAA
TGCCCGAAAAAAGTGAGACG

Product: nicotinate phosphoribosyltransferase

Products: NA

Alternate protein names: NAPRTase [H]

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MIIHSLLDTDLYKFTMMQAVLHQHPAAQVDYRFKCRTPGVDLAQFVDEISREIDALCRLRLREDEVDYLRSLRFIKPDFA
DFLALFHLDRKYLSLTASATHPGEIELTIRGPWLHTILFEVPLLAIINEVWFRNTSEPDFEEGRSRLREKVASLRSMPAG
CKIADYGTRRRYSRQWHGELLPLLRDGLGEQFVGTSNVYFAKQYGLTPLGTMAHEYLQAFQALGPRLRDSQVAALESWAR
EYRGDLGIALSDVVGLDAFLRDFDLYFCKLFDGMRHDSGDPFEWGERVIAHLEAHRVDPRTKVLVFSDGLNIDKVMRLYQ
HFHTRCRLAFGVGTSLTNDLGPTPLQIVIKMVRCNGQPVAKLSDSPGKSMCEDIGYLRYLRDVFGLPPMAEG

Sequences:

>Translated_392_residues
MIIHSLLDTDLYKFTMMQAVLHQHPAAQVDYRFKCRTPGVDLAQFVDEISREIDALCRLRLREDEVDYLRSLRFIKPDFA
DFLALFHLDRKYLSLTASATHPGEIELTIRGPWLHTILFEVPLLAIINEVWFRNTSEPDFEEGRSRLREKVASLRSMPAG
CKIADYGTRRRYSRQWHGELLPLLRDGLGEQFVGTSNVYFAKQYGLTPLGTMAHEYLQAFQALGPRLRDSQVAALESWAR
EYRGDLGIALSDVVGLDAFLRDFDLYFCKLFDGMRHDSGDPFEWGERVIAHLEAHRVDPRTKVLVFSDGLNIDKVMRLYQ
HFHTRCRLAFGVGTSLTNDLGPTPLQIVIKMVRCNGQPVAKLSDSPGKSMCEDIGYLRYLRDVFGLPPMAEG
>Mature_392_residues
MIIHSLLDTDLYKFTMMQAVLHQHPAAQVDYRFKCRTPGVDLAQFVDEISREIDALCRLRLREDEVDYLRSLRFIKPDFA
DFLALFHLDRKYLSLTASATHPGEIELTIRGPWLHTILFEVPLLAIINEVWFRNTSEPDFEEGRSRLREKVASLRSMPAG
CKIADYGTRRRYSRQWHGELLPLLRDGLGEQFVGTSNVYFAKQYGLTPLGTMAHEYLQAFQALGPRLRDSQVAALESWAR
EYRGDLGIALSDVVGLDAFLRDFDLYFCKLFDGMRHDSGDPFEWGERVIAHLEAHRVDPRTKVLVFSDGLNIDKVMRLYQ
HFHTRCRLAFGVGTSLTNDLGPTPLQIVIKMVRCNGQPVAKLSDSPGKSMCEDIGYLRYLRDVFGLPPMAEG

Specific function: NAD biosynthesis; nicotinamide to NaMN; second step. [C]

COG id: COG1488

COG function: function code H; Nicotinic acid phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAPRTase family [H]

Homologues:

Organism=Escherichia coli, GI1787162, Length=398, Percent_Identity=43.7185929648241, Blast_Score=336, Evalue=1e-93,
Organism=Saccharomyces cerevisiae, GI6324783, Length=407, Percent_Identity=28.992628992629, Blast_Score=189, Evalue=8e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006406
- InterPro:   IPR015977
- InterPro:   IPR007229
- InterPro:   IPR002638 [H]

Pfam domain/function: PF04095 NAPRTase [H]

EC number: =2.4.2.11 [H]

Molecular weight: Translated: 44862; Mature: 44862

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIHSLLDTDLYKFTMMQAVLHQHPAAQVDYRFKCRTPGVDLAQFVDEISREIDALCRLR
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
LREDEVDYLRSLRFIKPDFADFLALFHLDRKYLSLTASATHPGEIELTIRGPWLHTILFE
CCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEEEECCCCCCEEEEEEECCHHHHHHHH
VPLLAIINEVWFRNTSEPDFEEGRSRLREKVASLRSMPAGCKIADYGTRRRYSRQWHGEL
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHH
LPLLRDGLGEQFVGTSNVYFAKQYGLTPLGTMAHEYLQAFQALGPRLRDSQVAALESWAR
HHHHHHCCCCHHCCCCCEEEEHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
EYRGDLGIALSDVVGLDAFLRDFDLYFCKLFDGMRHDSGDPFEWGERVIAHLEAHRVDPR
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCC
TKVLVFSDGLNIDKVMRLYQHFHTRCRLAFGVGTSLTNDLGPTPLQIVIKMVRCNGQPVA
CEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHHCCCCCCC
KLSDSPGKSMCEDIGYLRYLRDVFGLPPMAEG
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MIIHSLLDTDLYKFTMMQAVLHQHPAAQVDYRFKCRTPGVDLAQFVDEISREIDALCRLR
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
LREDEVDYLRSLRFIKPDFADFLALFHLDRKYLSLTASATHPGEIELTIRGPWLHTILFE
CCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEEEECCCCCCEEEEEEECCHHHHHHHH
VPLLAIINEVWFRNTSEPDFEEGRSRLREKVASLRSMPAGCKIADYGTRRRYSRQWHGEL
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHH
LPLLRDGLGEQFVGTSNVYFAKQYGLTPLGTMAHEYLQAFQALGPRLRDSQVAALESWAR
HHHHHHCCCCHHCCCCCEEEEHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
EYRGDLGIALSDVVGLDAFLRDFDLYFCKLFDGMRHDSGDPFEWGERVIAHLEAHRVDPR
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCC
TKVLVFSDGLNIDKVMRLYQHFHTRCRLAFGVGTSLTNDLGPTPLQIVIKMVRCNGQPVA
CEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHHCCCCCCC
KLSDSPGKSMCEDIGYLRYLRDVFGLPPMAEG
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA