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The map label for this gene is pilA [H]

Identifier: 78048909

GI number: 78048909

Start: 3840484

End: 3840912

Strand: Reverse

Name: pilA [H]

Synonym: XCV3353

Alternate gene names: 78048909

Gene position: 3840912-3840484 (Counterclockwise)

Preceding gene: 78048920

Following gene: 78048908

Centisome position: 74.17

GC content: 59.21

Gene sequence:

>429_bases
ATGAAGAAGCAAAACGGCTTTACCCTTATCGAACTGATGATCGTTGTCGCGATCATCGCAATCCTTGCCGCCATCGCGTT
GCCGGCCTACCAGGACTACACCGTTCGCGGCCGCGTCTCTGAAGCGATGGTTGCCGCGTCTGCCGCCAAGACGGTGGTGG
CCGAAAATGCCGCCAACGGCTCTGCCCTGAATAGCGGGTGGACCGCTCCTACGGCGACCAATAATGTTGCCAGCGTAGCC
GTTGCTGCCGCTACGGGCAATATTACTGTGACCACTACCGATAAGGCCGGCGGCGGCACGATCATTTTTGCTCCCACCGC
TAACGGCGCTGCGCTGACTTCCGGCACCGTTCCTACCGATCGCATTTCGTGGGATTGCAAGGGTGGCACCTTGGTTGCCA
AGTACCGTCCGGCTGAATGCCGTACCTAA

Upstream 100 bases:

>100_bases
TGGCACGTAACCTGCTTGATCCCACTTGCACGACCACCGCGGACCGGTTCCAACACACCTACGTCCGCCTCGATTACCAC
AACCTCTTGGGGATGCATCT

Downstream 100 bases:

>100_bases
TCTGCTGATTTGTATCGCAGCTACAGCTAAGCTATTTGCCAAGCCCGCAGATGCGGGCTTGGTTTTTTGTCTTTCTGTTG
GCGAAAAGATAGGAAGTAGT

Product: Tfp pilus assembly protein major pilin

Products: NA

Alternate protein names: L-pilin [H]

Number of amino acids: Translated: 142; Mature: 142

Protein sequence:

>142_residues
MKKQNGFTLIELMIVVAIIAILAAIALPAYQDYTVRGRVSEAMVAASAAKTVVAENAANGSALNSGWTAPTATNNVASVA
VAAATGNITVTTTDKAGGGTIIFAPTANGAALTSGTVPTDRISWDCKGGTLVAKYRPAECRT

Sequences:

>Translated_142_residues
MKKQNGFTLIELMIVVAIIAILAAIALPAYQDYTVRGRVSEAMVAASAAKTVVAENAANGSALNSGWTAPTATNNVASVA
VAAATGNITVTTTDKAGGGTIIFAPTANGAALTSGTVPTDRISWDCKGGTLVAKYRPAECRT
>Mature_142_residues
MKKQNGFTLIELMIVVAIIAILAAIALPAYQDYTVRGRVSEAMVAASAAKTVVAENAANGSALNSGWTAPTATNNVASVA
VAAATGNITVTTTDKAGGGTIIFAPTANGAALTSGTVPTDRISWDCKGGTLVAKYRPAECRT

Specific function: This protein is the predominant Neisseria surface antigen, which allows adhesion of the bacterium to various host cells [H]

COG id: COG4969

COG function: function code NU; Tfp pilus assembly protein, major pilin PilA

Gene ontology:

Cell location: Fimbrium [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N-Me-Phe pilin family [H]

Homologues:

Organism=Escherichia coli, GI1786297, Length=118, Percent_Identity=35.5932203389831, Blast_Score=67, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001082
- InterPro:   IPR012902
- InterPro:   IPR001120 [H]

Pfam domain/function: PF07963 N_methyl; PF00114 Pilin [H]

EC number: NA

Molecular weight: Translated: 14344; Mature: 14344

Theoretical pI: Translated: 9.23; Mature: 9.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKQNGFTLIELMIVVAIIAILAAIALPAYQDYTVRGRVSEAMVAASAAKTVVAENAANG
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHEECCCCCC
SALNSGWTAPTATNNVASVAVAAATGNITVTTTDKAGGGTIIFAPTANGAALTSGTVPTD
CCCCCCCCCCCCCCCCEEEEEEEECCCEEEEECCCCCCCEEEEEECCCCCEEECCCCCCC
RISWDCKGGTLVAKYRPAECRT
CEEEECCCCEEEEEECCCCCCC
>Mature Secondary Structure
MKKQNGFTLIELMIVVAIIAILAAIALPAYQDYTVRGRVSEAMVAASAAKTVVAENAANG
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHEECCCCCC
SALNSGWTAPTATNNVASVAVAAATGNITVTTTDKAGGGTIIFAPTANGAALTSGTVPTD
CCCCCCCCCCCCCCCCEEEEEEEECCCEEEEECCCCCCCEEEEEECCCCCEEECCCCCCC
RISWDCKGGTLVAKYRPAECRT
CEEEECCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1906968 [H]