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The map label for this gene is cysQ [H]

Identifier: 78048756

GI number: 78048756

Start: 3637884

End: 3638684

Strand: Reverse

Name: cysQ [H]

Synonym: XCV3200

Alternate gene names: 78048756

Gene position: 3638684-3637884 (Counterclockwise)

Preceding gene: 78048757

Following gene: 78048755

Centisome position: 70.27

GC content: 67.92

Gene sequence:

>801_bases
ATGATCCGCATCCCGATGGAGCTGCGCGAAACCGTGATCGCCATCGCGCGCGATGCCGGCGCCGCAATCATGGAGGTCTA
CGCCCAGGACTTTTCGGTGGAGATCAAGGACGACGCCAGCCCGCTGACCCAGGCCGACCTGGTAGCCAACCGCGTCATCG
TCGAAGGCCTGCGCCGTGTCACCCCGGACGTGCCGGTGCTGTCGGAAGAGTCTGCGCATGTGGCCTGGGAACAACGCCAG
TACTGGACCAGTTACTGGTTGGTCGATCCGCTCGATGGCACCCGCGAATTCGTCAAGCGCAATGGCGAGTTCAGCGTCAA
CATCGCACTCATCCATATGGGCGCACCGGTGCTCGGGGTGGTGCAGGCGCCGGTCGACGGGCGGGTCTGGTACGCCGCGC
GCGGCGAGAATGCCTTCCGCCGCGATGGCGACCGCGACGAGATGCTGCACACGCGCACCCCGGCCGCCACGCCATTGCGG
GTGGCGGCCAGCCGTTCGCATCGCGACGCGCGTACGGCCGCCGCGCTGGAGCGGATGGGCGAGATCGACGTGGTCGCGCA
AGGGTCGTCGTTGAAGTTCTGCCGCATCGCCGAAGGCGATCTGGACGTGTATCCCCGCTTCGGCCCCACCTCCGAGTGGG
ACACCGCCGCCGGCCAGTGCGTGCTGCATGCGGCCGGTGGCGTGTTGCTGGCCGGCGCCAGCGGCAAACCGTTCCGCTAC
AACCGCCGCGACACCTTGCTCAACGGCGACTTCATCGCACTGGGCGACCCCAATCTGCCCTGGCGCGATTGGCTGGCCTG
A

Upstream 100 bases:

>100_bases
CGATCGCACGTCTGGACGAATTGATGCTGCGCGAAGATTTCTCCGAAGGCCGCTCGCTGGCCGCCTTGTTCATTGCGCGC
GAGTGGCTGGAGCGCAATCC

Downstream 100 bases:

>100_bases
GCGGCATGCGTGCCGTCTTGGCGACGGCATGGCTGTGCAAGGCCCTGACGCCCTGAAAGGTACACTCCGGTATCCCAGCA
CGCGCTTGCGTGCCGCGCGC

Product: sulfite synthesis pathway protein

Products: NA

Alternate protein names: 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; DPNPase [H]

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MIRIPMELRETVIAIARDAGAAIMEVYAQDFSVEIKDDASPLTQADLVANRVIVEGLRRVTPDVPVLSEESAHVAWEQRQ
YWTSYWLVDPLDGTREFVKRNGEFSVNIALIHMGAPVLGVVQAPVDGRVWYAARGENAFRRDGDRDEMLHTRTPAATPLR
VAASRSHRDARTAAALERMGEIDVVAQGSSLKFCRIAEGDLDVYPRFGPTSEWDTAAGQCVLHAAGGVLLAGASGKPFRY
NRRDTLLNGDFIALGDPNLPWRDWLA

Sequences:

>Translated_266_residues
MIRIPMELRETVIAIARDAGAAIMEVYAQDFSVEIKDDASPLTQADLVANRVIVEGLRRVTPDVPVLSEESAHVAWEQRQ
YWTSYWLVDPLDGTREFVKRNGEFSVNIALIHMGAPVLGVVQAPVDGRVWYAARGENAFRRDGDRDEMLHTRTPAATPLR
VAASRSHRDARTAAALERMGEIDVVAQGSSLKFCRIAEGDLDVYPRFGPTSEWDTAAGQCVLHAAGGVLLAGASGKPFRY
NRRDTLLNGDFIALGDPNLPWRDWLA
>Mature_266_residues
MIRIPMELRETVIAIARDAGAAIMEVYAQDFSVEIKDDASPLTQADLVANRVIVEGLRRVTPDVPVLSEESAHVAWEQRQ
YWTSYWLVDPLDGTREFVKRNGEFSVNIALIHMGAPVLGVVQAPVDGRVWYAARGENAFRRDGDRDEMLHTRTPAATPLR
VAASRSHRDARTAAALERMGEIDVVAQGSSLKFCRIAEGDLDVYPRFGPTSEWDTAAGQCVLHAAGGVLLAGASGKPFRY
NRRDTLLNGDFIALGDPNLPWRDWLA

Specific function: Converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP. May also convert adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) [H]

COG id: COG1218

COG function: function code P; 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI5031789, Length=247, Percent_Identity=25.9109311740891, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI221625487, Length=245, Percent_Identity=24.8979591836735, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI7657236, Length=247, Percent_Identity=27.5303643724696, Blast_Score=72, Evalue=5e-13,
Organism=Escherichia coli, GI1790659, Length=246, Percent_Identity=50, Blast_Score=208, Evalue=3e-55,
Organism=Escherichia coli, GI1788882, Length=259, Percent_Identity=27.7992277992278, Blast_Score=73, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71995897, Length=237, Percent_Identity=27.8481012658228, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI71995905, Length=237, Percent_Identity=27.8481012658228, Blast_Score=81, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6320493, Length=246, Percent_Identity=25.609756097561, Blast_Score=78, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24641722, Length=261, Percent_Identity=24.904214559387, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006240
- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 29383; Mature: 29383

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS00629 IMP_1 ; PS00630 IMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRIPMELRETVIAIARDAGAAIMEVYAQDFSVEIKDDASPLTQADLVANRVIVEGLRRV
CEECCHHHHHHHHHHHHCCCHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHHHHHHC
TPDVPVLSEESAHVAWEQRQYWTSYWLVDPLDGTREFVKRNGEFSVNIALIHMGAPVLGV
CCCCCCCCCCCCCEEHHHHHHEEEEEEECCCCHHHHHHHCCCCEEEEEEEEEECCCEEEE
VQAPVDGRVWYAARGENAFRRDGDRDEMLHTRTPAATPLRVAASRSHRDARTAAALERMG
EECCCCCEEEEEECCCCHHHCCCCHHHHEECCCCCCCCEEEECCCCCCHHHHHHHHHHCC
EIDVVAQGSSLKFCRIAEGDLDVYPRFGPTSEWDTAAGQCVLHAAGGVLLAGASGKPFRY
CEEEEECCCCCEEEEEECCCCEECCCCCCCCCCCCCCCCEEEEECCCEEEECCCCCCEEE
NRRDTLLNGDFIALGDPNLPWRDWLA
CCCCEEECCCEEEECCCCCCHHHHCC
>Mature Secondary Structure
MIRIPMELRETVIAIARDAGAAIMEVYAQDFSVEIKDDASPLTQADLVANRVIVEGLRRV
CEECCHHHHHHHHHHHHCCCHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHHHHHHC
TPDVPVLSEESAHVAWEQRQYWTSYWLVDPLDGTREFVKRNGEFSVNIALIHMGAPVLGV
CCCCCCCCCCCCCEEHHHHHHEEEEEEECCCCHHHHHHHCCCCEEEEEEEEEECCCEEEE
VQAPVDGRVWYAARGENAFRRDGDRDEMLHTRTPAATPLRVAASRSHRDARTAAALERMG
EECCCCCEEEEEECCCCHHHCCCCHHHHEECCCCCCCCEEEECCCCCCHHHHHHHHHHCC
EIDVVAQGSSLKFCRIAEGDLDVYPRFGPTSEWDTAAGQCVLHAAGGVLLAGASGKPFRY
CEEEEECCCCCEEEEEECCCCEECCCCCCCCCCCCCCCCEEEEECCCEEEECCCCCCEEE
NRRDTLLNGDFIALGDPNLPWRDWLA
CCCCEEECCCEEEECCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]